EE04916B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Info

Publication number
EE04916B1
EE04916B1 EEP200000664A EEP200000664A EE04916B1 EE 04916 B1 EE04916 B1 EE 04916B1 EE P200000664 A EEP200000664 A EE P200000664A EE P200000664 A EEP200000664 A EE P200000664A EE 04916 B1 EE04916 B1 EE 04916B1
Authority
EE
Estonia
Prior art keywords
rididine
imidazop
derivatives
gastric acid
acid secretion
Prior art date
Application number
EEP200000664A
Other languages
English (en)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000664A publication Critical patent/EE200000664A/et
Publication of EE04916B1 publication Critical patent/EE04916B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000664A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni EE04916B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000663 WO1999055706A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000664A EE200000664A (et) 2002-04-15
EE04916B1 true EE04916B1 (et) 2007-10-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Country Status (34)

Country Link
US (2) US6313136B1 (et)
EP (4) EP1491543B1 (et)
JP (2) JP3692034B2 (et)
KR (3) KR100595806B1 (et)
CN (2) CN1174980C (et)
AR (2) AR015768A1 (et)
AT (4) ATE307130T1 (et)
AU (2) AU769108B2 (et)
BR (2) BR9909996B1 (et)
CA (2) CA2329921A1 (et)
CZ (2) CZ293977B6 (et)
DE (4) DE69928792T2 (et)
DK (2) DK1073657T3 (et)
EE (2) EE04676B1 (et)
ES (2) ES2249913T3 (et)
HK (5) HK1033457A1 (et)
HU (2) HUP0102425A3 (et)
ID (2) ID26819A (et)
IL (4) IL139297A0 (et)
IS (2) IS5683A (et)
MY (2) MY121389A (et)
NO (2) NO318203B1 (et)
NZ (2) NZ507639A (et)
PL (2) PL195000B1 (et)
RU (2) RU2238271C2 (et)
SA (2) SA99200065B1 (et)
SE (1) SE9801526D0 (et)
SI (1) SI1073656T1 (et)
SK (2) SK285768B6 (et)
TR (4) TR200102612T2 (et)
TW (2) TWI250159B (et)
UA (2) UA67769C2 (et)
WO (2) WO1999055706A1 (et)
ZA (2) ZA200005797B (et)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
CA2434835A1 (en) * 2001-02-13 2002-08-22 Astrazeneca Ab Novel modified released formulation
US20040082605A1 (en) * 2001-03-08 2004-04-29 Arne Eek Use
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
KR20050052500A (ko) 2002-09-19 2005-06-02 쉐링 코포레이션 사이클린 의존성 키나제 억제제로서의 이미다조피리딘
JP2006508142A (ja) 2002-11-19 2006-03-09 アルタナ　ファルマ　アクチエンゲゼルシャフト ８−置換イミダゾピリジン
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
NZ541861A (en) * 2003-02-26 2009-05-31 Sugen Inc Aminoheteroaryl compounds as protein kinase inhibitors
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2591412A1 (en) * 2004-12-17 2006-06-22 Pfizer Inc. Chromane derivatives useful as acid pump antagonists
ES2421916T3 (es) 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
KR101300831B1 (ko) * 2005-03-21 2013-08-30 에스*바이오 피티이 리미티드 이미다조[1,2-ａ]피리딘 유도체, 이의 제조 방법 및 그의약학적 용도
JP2008536817A (ja) * 2005-03-24 2008-09-11 グラクソ グループ リミテッド 胃腸疾患の処置用医薬として有用なイミダゾ（１，２−ａ）ピリジン誘導体
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
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PT1963302E (pt) * 2005-12-05 2013-04-09 Pfizer Prod Inc Polimorfos de um inibidor de c-met/hgfr
WO2007107827A1 (en) * 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
WO2008013785A2 (en) 2006-07-24 2008-01-31 Singh-Broemer And Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
WO2009122435A2 (en) * 2008-03-31 2009-10-08 Council Of Scientific & Industrial Research A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
CN105919998B (zh) * 2009-07-09 2021-08-24 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂
BR112015030288B1 (pt) * 2013-06-25 2022-10-18 Ptc Therapeutics, Inc. Compostos e seu uso no tratamento de atrofia muscular espinhal
KR20220112867A (ko) 2013-12-16 2022-08-11 에이비에스 디벨롭먼트 원 인코포레이티드 P2x3 및/또는 p2x2/3 화합물 및 방법
TWI662033B (zh) * 2014-03-24 2019-06-11 美商亞闊股份有限公司 製備３－（３－（４－（１－胺基環丁基）苯基）－５－苯基－３Ｈ－咪唑並［４，５－ｂ］吡啶－２－基）吡啶－２－胺之方法
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
US11666888B2 (en) 2018-02-05 2023-06-06 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
JP7353295B2 (ja) * 2018-04-10 2023-09-29 バイエル・アクチエンゲゼルシヤフト ２，６－ジアルキルフェニル酢酸の製造方法
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
AU2020377451A1 (en) 2019-11-04 2022-05-26 Cinclus Pharma Holding AB Oral formulation of X842
MX2024005463A (es) 2021-11-05 2024-05-22 Cinclus Pharma Holding Ab Publ Polimorfos de la sal de mesilato de glurato de linaprazan.
IL312564A (en) 2021-11-05 2024-07-01 Cinclus Pharma Holding Ab Publ Polymorphs of the hydrochloride salt of linfarezan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
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ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
SA99200065A (ar) 2005-12-03
CN1174980C (zh) 2004-11-10
SK14922000A3 (sk) 2001-06-11
CN1307577A (zh) 2001-08-08
HK1036984A1 (en) 2002-01-25
EE200000626A (et) 2002-04-15
NO317262B1 (no) 2004-09-27
AU4300699A (en) 1999-11-16
HK1033457A1 (en) 2001-08-31
CA2329922C (en) 2006-04-11
DE69927803T2 (de) 2006-07-06
IS5683A (is) 2000-10-25
DE69937076D1 (de) 2007-10-18
NO20005450D0 (no) 2000-10-27
CN1165535C (zh) 2004-09-08
BR9909995B1 (pt) 2010-07-13
JP2002513025A (ja) 2002-05-08
UA66846C2 (uk) 2004-06-15
CZ20003982A3 (cs) 2001-02-14
AU4300799A (en) 1999-11-16
HK1033317A1 (en) 2001-08-24
IL139200A0 (en) 2001-11-25
NO318203B1 (no) 2005-02-14
BR9909996A (pt) 2000-12-26
NO20005451D0 (no) 2000-10-27
ATE372340T1 (de) 2007-09-15
EP1073657B1 (en) 2005-12-07
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
DE69928792D1 (de) 2006-01-12
EP1073656B1 (en) 2005-10-19
EE04676B1 (et) 2006-08-15
BR9909995A (pt) 2000-12-26
MY121379A (en) 2006-01-28
BR9909996B1 (pt) 2010-08-24
TW490466B (en) 2002-06-11
KR20010043133A (ko) 2001-05-25
DE69927803D1 (de) 2006-03-02
ZA200005797B (en) 2002-01-18
EP1073656A1 (en) 2001-02-07
HK1036981A1 (en) 2002-01-25
PL343801A1 (en) 2001-09-10
SK285768B6 (sk) 2007-07-06
ES2252975T3 (es) 2006-05-16
CZ20003981A3 (cs) 2001-03-14
JP3883383B2 (ja) 2007-02-21
PL195000B1 (pl) 2007-07-31
NZ507639A (en) 2004-01-30
SA99200065B1 (ar) 2006-11-07
CA2329922A1 (en) 1999-11-04
CA2329921A1 (en) 1999-11-04
EP1491542A2 (en) 2004-12-29
CZ293977B6 (cs) 2004-09-15
SA99200064B1 (ar) 2006-10-11
US6313136B1 (en) 2001-11-06
TR200003149T2 (tr) 2001-03-21
DE69937077D1 (de) 2007-10-18
NZ507638A (en) 2003-10-31
ES2249913T3 (es) 2006-04-01
IL139297A0 (en) 2001-11-25
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
TR200102728T2 (tr) 2002-06-21
DE69937077T2 (de) 2008-05-29
SE9801526D0 (sv) 1998-04-29
HUP0102425A3 (en) 2002-12-28
ATE312101T1 (de) 2005-12-15
ATE372339T1 (de) 2007-09-15
UA67769C2 (uk) 2004-07-15
NO20005451L (no) 2000-12-27
AR015768A1 (es) 2001-05-16
EP1073657A1 (en) 2001-02-07
RU2235725C2 (ru) 2004-09-10
WO1999055705A1 (en) 1999-11-04
DK1073657T3 (da) 2006-03-13
ATE307130T1 (de) 2005-11-15
SK14912000A3 (sk) 2001-06-11
AR015769A1 (es) 2001-05-16
MY121389A (en) 2006-01-28
TR200102612T2 (tr) 2002-06-21
RU2238271C2 (ru) 2004-10-20
HK1071139A1 (en) 2005-07-08
ID26819A (id) 2001-02-15
KR100595806B1 (ko) 2006-07-03
EP1491542A3 (en) 2005-01-05
DE69937076T2 (de) 2008-05-29
ID27530A (id) 2001-04-12
TR200003176T2 (tr) 2001-03-21
EP1491543B1 (en) 2007-09-05
WO1999055706A9 (en) 2000-03-16
CN1306533A (zh) 2001-08-01
JP3692034B2 (ja) 2005-09-07
AU769190B2 (en) 2004-01-22
ZA200005796B (en) 2002-01-18
EP1491543A1 (en) 2004-12-29
HUP0102313A2 (hu) 2001-12-28
TWI250159B (en) 2006-03-01
KR100595805B1 (ko) 2006-07-03
US6313137B1 (en) 2001-11-06
IL139297A (en) 2007-06-03
HUP0102425A2 (hu) 2001-11-28
KR100650472B1 (ko) 2006-11-28
IL139200A (en) 2010-04-29
JP2002513024A (ja) 2002-05-08
IS5684A (is) 2000-10-25
NO20005450L (no) 2000-12-22
PL343797A1 (en) 2001-09-10
KR20010043134A (ko) 2001-05-25
DK1073656T3 (da) 2006-01-16
KR20050121760A (ko) 2005-12-27
AU769108B2 (en) 2004-01-15
HUP0102313A3 (en) 2002-10-28
CZ292567B6 (cs) 2003-10-15
DE69928792T2 (de) 2006-07-20

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