BR9909995B1 - composto, processo para a preparação de um composto, formulação farmacêutica, e, uso de um composto. - Google Patents

composto, processo para a preparação de um composto, formulação farmacêutica, e, uso de um composto.

Info

Publication number
BR9909995B1
BR9909995B1 BRPI9909995-0A BR9909995A BR9909995B1 BR 9909995 B1 BR9909995 B1 BR 9909995B1 BR 9909995 A BR9909995 A BR 9909995A BR 9909995 B1 BR9909995 B1 BR 9909995B1
Authority
BR
Brazil
Prior art keywords
compound
preparing
pharmaceutical formulation
formulation
pharmaceutical
Prior art date
Application number
BRPI9909995-0A
Other languages
English (en)
Other versions
BR9909995A (pt
Inventor
Kosrat Amin
Dahlstroem Michael
Peter Nordberg
Ingemar Starke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9909995A publication Critical patent/BR9909995A/pt
Publication of BR9909995B1 publication Critical patent/BR9909995B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
BRPI9909995-0A 1998-04-29 1999-04-23 composto, processo para a preparação de um composto, formulação farmacêutica, e, uso de um composto. BR9909995B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
BR9909995A BR9909995A (pt) 2000-12-26
BR9909995B1 true BR9909995B1 (pt) 2010-07-13

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9909995-0A BR9909995B1 (pt) 1998-04-29 1999-04-23 composto, processo para a preparação de um composto, formulação farmacêutica, e, uso de um composto.
BRPI9909996-9A BR9909996B1 (pt) 1998-04-29 1999-04-23 composto derivado de imidazo piridina, processo para a preparaÇço de um composto, formulaÇço farmacÊutica, e, uso de um composto.

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI9909996-9A BR9909996B1 (pt) 1998-04-29 1999-04-23 composto derivado de imidazo piridina, processo para a preparaÇço de um composto, formulaÇço farmacÊutica, e, uso de um composto.

Country Status (34)

Country Link
US (2) US6313137B1 (pt)
EP (4) EP1491542B1 (pt)
JP (2) JP3692034B2 (pt)
KR (3) KR100650472B1 (pt)
CN (2) CN1165535C (pt)
AR (2) AR015769A1 (pt)
AT (4) ATE372339T1 (pt)
AU (2) AU769190B2 (pt)
BR (2) BR9909995B1 (pt)
CA (2) CA2329921A1 (pt)
CZ (2) CZ293977B6 (pt)
DE (4) DE69928792T2 (pt)
DK (2) DK1073656T3 (pt)
EE (2) EE04916B1 (pt)
ES (2) ES2249913T3 (pt)
HK (5) HK1033457A1 (pt)
HU (2) HUP0102313A3 (pt)
ID (2) ID26819A (pt)
IL (4) IL139297A0 (pt)
IS (2) IS5683A (pt)
MY (2) MY121379A (pt)
NO (2) NO318203B1 (pt)
NZ (2) NZ507639A (pt)
PL (2) PL343797A1 (pt)
RU (2) RU2235725C2 (pt)
SA (2) SA99200065B1 (pt)
SE (1) SE9801526D0 (pt)
SI (1) SI1073656T1 (pt)
SK (2) SK14912000A3 (pt)
TR (4) TR200003176T2 (pt)
TW (2) TW490466B (pt)
UA (2) UA66846C2 (pt)
WO (2) WO1999055706A1 (pt)
ZA (2) ZA200005796B (pt)

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US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
DE60211130T2 (de) * 2001-02-13 2006-11-30 Astrazeneca Ab Neue formulierung mit modifizierter freisetzung
MXPA03007888A (es) * 2001-03-08 2003-12-04 Astrazeneca Ab Compuestos para tratamiento y prevencion de ulcera gastrica inducida por medicamentos.
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
AU2003295332B2 (en) 2002-09-19 2007-01-18 Merck Sharp & Dohme Corp. Imidazopyridines as cyclin dependent kinase inhibitors
WO2004046144A1 (en) 2002-11-19 2004-06-03 Altana Pharma Ag 8-substituted imidazopyridines
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
DK2476667T3 (da) * 2003-02-26 2014-09-15 Sugen Inc Aminoheteroaryl-forbindelser som proteinkinase-inhibitorer
RS52908B (en) 2003-03-10 2014-02-28 Takeda Gmbh NEW PROCEDURE FOR OBTAINING ROFLUMILAST
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20080280944A1 (en) * 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1838309B1 (en) * 2004-12-17 2008-08-20 Pfizer, Inc. Chromane derivatives useful as acid pump antagonists
WO2006097456A1 (en) 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
AR056187A1 (es) * 2005-03-21 2007-09-26 S Bio Pte Ltd Derivados de imidazo[1,2-a)piridina: preparacion, composiciones farmaceuticas y uso para preparar medicamentos
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
AR055321A1 (es) * 2005-03-24 2007-08-15 Glaxo Group Ltd Compuestos de imidazopiridina uso para a fabricacion de un medicamento para el tratamiento o profilaxis de enfermedades o trastornos en los que se requiere un antagonista de una bomba de acido y composicion farmaceutica que lo comprende
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
KR101026676B1 (ko) * 2005-12-05 2011-04-04 화이자 프로덕츠 인코포레이티드 비정상 세포 성장의 치료 방법
PL1963302T3 (pl) * 2005-12-05 2013-06-28 Pfizer Prod Inc Polimorfy inhibitora c-Met/HGFR
CA2645007A1 (en) * 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
US8728527B2 (en) 2006-07-24 2014-05-20 Luminus Biosciences, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
CN102066396B (zh) * 2008-03-31 2014-03-12 科学与工业研究委员会 用作抗胃液分泌或抗溃疡剂的药物组合物
FI20086158A0 (fi) 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
AR096684A1 (es) * 2013-06-25 2016-01-27 Ptc Therapeutics Inc Compuestos para tratar atrofia muscular espinal
CN106029660B (zh) 2013-12-16 2019-11-15 阿萨纳生物科技有限责任公司 P2x3和/或p2x2/3化合物和方法
CN106459036B (zh) * 2014-03-24 2021-07-16 艾科尔公司 制备3-(3-(4-(1-氨基环丁基)苯基)-5-苯基-3H-咪唑并[4,5-b]吡啶-2-基)吡啶-2-胺的方法
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
EP3749697A4 (en) 2018-02-05 2021-11-03 Bio-Rad Laboratories, Inc. CHROMATOGRAPHIC RESIN WITH A LIGAND WITH ANION EXCHANGE-HYDROPHOBIC MIXED MODE
JP7353295B2 (ja) * 2018-04-10 2023-09-29 バイエル・アクチエンゲゼルシヤフト ２，６－ジアルキルフェニル酢酸の製造方法
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
US20220362223A1 (en) 2019-11-04 2022-11-17 Cinclus Pharma Holding AB Oral formulation of x842
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
WO2023079094A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrochloride salt of linaprazan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법

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Also Published As

Publication number Publication date
HUP0102425A2 (hu) 2001-11-28
RU2235725C2 (ru) 2004-09-10
AU4300799A (en) 1999-11-16
BR9909996A (pt) 2000-12-26
CZ293977B6 (cs) 2004-09-15
IS5684A (is) 2000-10-25
US6313137B1 (en) 2001-11-06
NO20005451L (no) 2000-12-27
HUP0102313A3 (en) 2002-10-28
HK1033317A1 (en) 2001-08-24
HK1071139A1 (en) 2005-07-08
EP1491542A2 (en) 2004-12-29
TR200003149T2 (tr) 2001-03-21
CZ292567B6 (cs) 2003-10-15
TWI250159B (en) 2006-03-01
HK1036981A1 (en) 2002-01-25
RU2238271C2 (ru) 2004-10-20
CZ20003982A3 (cs) 2001-02-14
CA2329922A1 (en) 1999-11-04
JP3883383B2 (ja) 2007-02-21
EE04916B1 (et) 2007-10-15
EP1073657B1 (en) 2005-12-07
BR9909996B1 (pt) 2010-08-24
HUP0102425A3 (en) 2002-12-28
AR015768A1 (es) 2001-05-16
JP3692034B2 (ja) 2005-09-07
NO317262B1 (no) 2004-09-27
DE69928792T2 (de) 2006-07-20
CN1174980C (zh) 2004-11-10
DE69927803D1 (de) 2006-03-02
ATE372340T1 (de) 2007-09-15
IL139297A (en) 2007-06-03
NO318203B1 (no) 2005-02-14
CN1165535C (zh) 2004-09-08
UA67769C2 (uk) 2004-07-15
CA2329921A1 (en) 1999-11-04
EE200000626A (et) 2002-04-15
EE04676B1 (et) 2006-08-15
AR015769A1 (es) 2001-05-16
EP1491542A3 (en) 2005-01-05
CA2329922C (en) 2006-04-11
KR100595805B1 (ko) 2006-07-03
SA99200065B1 (ar) 2006-11-07
PL195000B1 (pl) 2007-07-31
NO20005450D0 (no) 2000-10-27
DE69927803T2 (de) 2006-07-06
US6313136B1 (en) 2001-11-06
NO20005450L (no) 2000-12-22
PL343801A1 (en) 2001-09-10
EP1491542B1 (en) 2007-09-05
KR100650472B1 (ko) 2006-11-28
WO1999055706A9 (en) 2000-03-16
PL343797A1 (en) 2001-09-10
AU769108B2 (en) 2004-01-15
TW490466B (en) 2002-06-11
ATE312101T1 (de) 2005-12-15
DK1073657T3 (da) 2006-03-13
SA99200065A (ar) 2005-12-03
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
SK285768B6 (sk) 2007-07-06
JP2002513024A (ja) 2002-05-08
ID26819A (id) 2001-02-15
KR20010043133A (ko) 2001-05-25
NO20005451D0 (no) 2000-10-27
KR20010043134A (ko) 2001-05-25
AU769190B2 (en) 2004-01-22
HK1033457A1 (en) 2001-08-31
MY121389A (en) 2006-01-28
IL139297A0 (en) 2001-11-25
DK1073656T3 (da) 2006-01-16
CZ20003981A3 (cs) 2001-03-14
CN1307577A (zh) 2001-08-08
KR100595806B1 (ko) 2006-07-03
JP2002513025A (ja) 2002-05-08
EP1073656A1 (en) 2001-02-07
DE69928792D1 (de) 2006-01-12
ES2249913T3 (es) 2006-04-01
EE200000664A (et) 2002-04-15
EP1073657A1 (en) 2001-02-07
HK1036984A1 (en) 2002-01-25
ATE307130T1 (de) 2005-11-15
DE69937076D1 (de) 2007-10-18
ID27530A (id) 2001-04-12
SK14922000A3 (sk) 2001-06-11
EP1491543B1 (en) 2007-09-05
CN1306533A (zh) 2001-08-01
IL139200A0 (en) 2001-11-25
MY121379A (en) 2006-01-28
NZ507639A (en) 2004-01-30
TR200003176T2 (tr) 2001-03-21
EP1491543A1 (en) 2004-12-29
HUP0102313A2 (hu) 2001-12-28
TR200102612T2 (tr) 2002-06-21
AU4300699A (en) 1999-11-16
IS5683A (is) 2000-10-25
ES2252975T3 (es) 2006-05-16
UA66846C2 (uk) 2004-06-15
KR20050121760A (ko) 2005-12-27
SA99200064B1 (ar) 2006-10-11
ATE372339T1 (de) 2007-09-15
DE69937077T2 (de) 2008-05-29
SK14912000A3 (sk) 2001-06-11
IL139200A (en) 2010-04-29
NZ507638A (en) 2003-10-31
WO1999055705A1 (en) 1999-11-04
EP1073656B1 (en) 2005-10-19
SE9801526D0 (sv) 1998-04-29
DE69937077D1 (de) 2007-10-18
TR200102728T2 (tr) 2002-06-21
ZA200005797B (en) 2002-01-18
DE69937076T2 (de) 2008-05-29
BR9909995A (pt) 2000-12-26
ZA200005796B (en) 2002-01-18

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
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