PL1963302T3 - Polimorfy inhibitora c-Met/HGFR - Google Patents
Polimorfy inhibitora c-Met/HGFRInfo
- Publication number
- PL1963302T3 PL1963302T3 PL06820988T PL06820988T PL1963302T3 PL 1963302 T3 PL1963302 T3 PL 1963302T3 PL 06820988 T PL06820988 T PL 06820988T PL 06820988 T PL06820988 T PL 06820988T PL 1963302 T3 PL1963302 T3 PL 1963302T3
- Authority
- PL
- Poland
- Prior art keywords
- polymorphs
- met
- hgfr inhibitor
- hgfr
- inhibitor
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74267605P | 2005-12-05 | 2005-12-05 | |
| PCT/IB2006/003383 WO2007066185A2 (en) | 2005-12-05 | 2006-11-23 | Polymorphs of a c-met/hgfr inhibitor |
| EP06820988A EP1963302B1 (en) | 2005-12-05 | 2006-11-23 | Polymorphs of a c-met/hgfr inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1963302T3 true PL1963302T3 (pl) | 2013-06-28 |
Family
ID=38123249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06820988T PL1963302T3 (pl) | 2005-12-05 | 2006-11-23 | Polimorfy inhibitora c-Met/HGFR |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8217057B2 (pl) |
| EP (1) | EP1963302B1 (pl) |
| JP (1) | JP4663619B2 (pl) |
| KR (1) | KR101146852B1 (pl) |
| CN (1) | CN101326175B (pl) |
| AR (1) | AR057964A1 (pl) |
| AU (1) | AU2006323025B2 (pl) |
| CA (1) | CA2632283C (pl) |
| DK (1) | DK1963302T3 (pl) |
| ES (1) | ES2402419T3 (pl) |
| IL (1) | IL191971A (pl) |
| NZ (1) | NZ568289A (pl) |
| PL (1) | PL1963302T3 (pl) |
| PT (1) | PT1963302E (pl) |
| RU (1) | RU2387650C2 (pl) |
| SI (1) | SI1963302T1 (pl) |
| TW (1) | TWI389902B (pl) |
| WO (1) | WO2007066185A2 (pl) |
| ZA (1) | ZA200804374B (pl) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4242911B2 (ja) | 2004-08-26 | 2009-03-25 | ファイザー・インク | プロテインキナーゼ阻害薬としてのエナンチオピュアなアミノヘテロアリール化合物 |
| DE602006018354D1 (de) * | 2005-12-05 | 2010-12-30 | Pfizer Prod Inc | Verfahren zur behandlung von abnormalem zellwachstum |
| JP2011511005A (ja) * | 2008-02-04 | 2011-04-07 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | ２−アミノピリジン系キナーゼ阻害薬 |
| AR070317A1 (es) * | 2008-02-06 | 2010-03-31 | Osi Pharm Inc | Furo (3,2-c) piridina y tieno (3,2-c) piridinas |
| EP2356116A1 (en) * | 2008-11-20 | 2011-08-17 | OSI Pharmaceuticals, Inc. | Substituted pyrroloý2,3-b¨-pyridines and-pyrazines |
| CA2796967C (en) | 2010-05-04 | 2015-12-01 | Pfizer Inc. | Heterocyclic derivatives as alk inhibitors |
| US20130072495A1 (en) | 2010-05-14 | 2013-03-21 | OSI Pharmaceuticals, LLC | Fused bicyclic kinase inhibitors |
| AR081039A1 (es) | 2010-05-14 | 2012-05-30 | Osi Pharmaceuticals Llc | Inhibidores biciclicos fusionados de quinasa |
| EP2606886B1 (en) | 2010-08-20 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Composition comprising tetracyclic compound |
| WO2012042421A1 (en) | 2010-09-29 | 2012-04-05 | Pfizer Inc. | Method of treating abnormal cell growth |
| JP2014513724A (ja) | 2011-05-16 | 2014-06-05 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 融合二環キナーゼ阻害剤 |
| RU2013155695A (ru) | 2011-06-30 | 2015-08-10 | Дженентек, Инк. | Препараты антител против с-мет |
| EP2620140A1 (en) | 2012-01-26 | 2013-07-31 | ratiopharm GmbH | Crizotinib containing compositions |
| CA2863892C (en) | 2012-03-06 | 2016-08-30 | Pfizer Inc. | Macrocyclic derivatives for the treatment of proliferative diseases |
| WO2013181251A1 (en) | 2012-05-29 | 2013-12-05 | Ratiopharm Gmbh | Crizotinib hydrochloride salt in crystalline |
| WO2014046730A1 (en) | 2012-09-24 | 2014-03-27 | Ventana Medical Systems, Inc. | Method of identifying treatment responsive non-small cell lung cancer using anaplastic lymphoma kinase (alk) as a marker |
| WO2014115169A2 (en) * | 2013-01-24 | 2014-07-31 | Hetero Research Foundation | Crizotinib solid dispersion |
| EP3066118B1 (en) | 2013-11-06 | 2020-01-08 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Alk antibodies, conjugates, and chimeric antigen receptors, and their use |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| WO2015163448A1 (ja) | 2014-04-25 | 2015-10-29 | 中外製薬株式会社 | ４環性化合物を高用量含有する製剤 |
| US10695426B2 (en) | 2014-08-25 | 2020-06-30 | Pfizer Inc. | Combination of a PD-1 antagonist and an ALK inhibitor for treating cancer |
| WO2016169030A1 (zh) * | 2015-04-23 | 2016-10-27 | 正大天晴药业集团股份有限公司 | 吡啶胺化合物的富马酸盐及其晶体 |
| CN106220644B (zh) | 2015-04-24 | 2020-07-31 | 广州再极医药科技有限公司 | 稠环嘧啶氨基衍生物﹑其制备方法、中间体、药物组合物及应用 |
| JP2018529719A (ja) | 2015-09-30 | 2018-10-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ａｌｋ陰性がんを処置するためのｐｄ−１系結合アンタゴニストおよびａｌｋ阻害剤の組合せ |
| HRP20220237T1 (hr) | 2016-05-20 | 2022-04-29 | Biohaven Therapeutics Ltd. | Primjena riluzola, prolijekova riluzola ili analoga riluzola sa imunoterapijama za liječenje raka |
| TWI646094B (zh) * | 2016-06-01 | 2019-01-01 | 大陸商貝達藥業股份有限公司 | Crystal form of inhibitory protein kinase active compound and application thereof |
| CN108727337A (zh) * | 2018-07-03 | 2018-11-02 | 无锡富泽药业有限公司 | 一种克唑替尼中间体的制备方法 |
| CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| CA3149796A1 (en) | 2019-08-02 | 2021-02-11 | Onehealthcompany, Inc. | Anti-cancer agents for the treatment of canine cancers |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| WO2023086671A1 (en) * | 2021-11-15 | 2023-05-19 | The Broad Institute, Inc. | Compounds, compositions, and methods for inducing antimicrobial intracellular activity and for preventing and treating microbial infections |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4725601A (en) | 1985-06-04 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers |
| GB9201693D0 (en) | 1992-01-27 | 1992-03-11 | Smithkline Beecham Intercredit | Compounds |
| JPH07109260A (ja) | 1993-10-12 | 1995-04-25 | Fuji Photo Film Co Ltd | ５−アミノ−２−ニトロピリジン誘導体及び２，５−ジアミノ−３−ヒドロキシピリジン誘導体の製造方法 |
| SE9700661D0 (sv) | 1997-02-25 | 1997-02-25 | Astra Ab | New compounds |
| SE9801526D0 (sv) | 1998-04-29 | 1998-04-29 | Astra Ab | New compounds |
| GB9908410D0 (en) | 1999-04-13 | 1999-06-09 | Pfizer Ltd | Pyridines |
| EP1206265B1 (en) | 1999-06-30 | 2003-11-12 | Merck & Co., Inc. | Src kinase inhibitor compounds |
| ATE307121T1 (de) | 2000-02-16 | 2005-11-15 | Neurogen Corp | Substituierte arylpyrazine |
| HUP0700086A2 (en) * | 2000-08-11 | 2007-05-29 | Eisai Co Ltd | 2-aminopyridine compounds, use thereof as drugs and pharmaceutical compositions containing them |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| US6825198B2 (en) | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| US6992087B2 (en) | 2001-11-21 | 2006-01-31 | Pfizer Inc | Substituted aryl 1,4-pyrazine derivatives |
| PT2476667E (pt) | 2003-02-26 | 2014-09-18 | Sugen Inc | Compostos de aminoheteroarilo como inibidores da proteína quinase |
| JP4242911B2 (ja) * | 2004-08-26 | 2009-03-25 | ファイザー・インク | プロテインキナーゼ阻害薬としてのエナンチオピュアなアミノヘテロアリール化合物 |
| CA2577937C (en) * | 2004-08-26 | 2010-12-21 | Pfizer Inc. | Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors |
| EP1786777A1 (en) | 2004-08-26 | 2007-05-23 | Pfizer, Inc. | Aminoheteroaryl compounds as protein tyrosine kinase inhibitors |
| DE602006018354D1 (de) * | 2005-12-05 | 2010-12-30 | Pfizer Prod Inc | Verfahren zur behandlung von abnormalem zellwachstum |
-
2006
- 2006-11-23 PT PT68209881T patent/PT1963302E/pt unknown
- 2006-11-23 ES ES06820988T patent/ES2402419T3/es active Active
- 2006-11-23 WO PCT/IB2006/003383 patent/WO2007066185A2/en not_active Ceased
- 2006-11-23 NZ NZ568289A patent/NZ568289A/en unknown
- 2006-11-23 CA CA2632283A patent/CA2632283C/en active Active
- 2006-11-23 PL PL06820988T patent/PL1963302T3/pl unknown
- 2006-11-23 SI SI200631544T patent/SI1963302T1/sl unknown
- 2006-11-23 EP EP06820988A patent/EP1963302B1/en active Active
- 2006-11-23 CN CN2006800458831A patent/CN101326175B/zh active Active
- 2006-11-23 RU RU2008120338/04A patent/RU2387650C2/ru active Protection Beyond IP Right Term
- 2006-11-23 DK DK06820988.1T patent/DK1963302T3/da active
- 2006-11-23 KR KR1020087013452A patent/KR101146852B1/ko active Active
- 2006-11-23 US US12/095,116 patent/US8217057B2/en active Active
- 2006-11-23 AU AU2006323025A patent/AU2006323025B2/en active Active
- 2006-12-04 AR ARP060105349A patent/AR057964A1/es not_active Application Discontinuation
- 2006-12-04 JP JP2006326483A patent/JP4663619B2/ja active Active
- 2006-12-04 TW TW095144946A patent/TWI389902B/zh active
-
2008
- 2008-05-21 ZA ZA200804374A patent/ZA200804374B/xx unknown
- 2008-06-05 IL IL191971A patent/IL191971A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US20080293769A1 (en) | 2008-11-27 |
| ES2402419T3 (es) | 2013-05-03 |
| NZ568289A (en) | 2011-06-30 |
| RU2008120338A (ru) | 2010-01-20 |
| JP2007153893A (ja) | 2007-06-21 |
| KR101146852B1 (ko) | 2012-05-16 |
| EP1963302A2 (en) | 2008-09-03 |
| DK1963302T3 (da) | 2013-04-02 |
| US8217057B2 (en) | 2012-07-10 |
| HK1126477A1 (en) | 2009-09-04 |
| CN101326175B (zh) | 2012-07-18 |
| EP1963302B1 (en) | 2013-02-27 |
| BRPI0619420A2 (pt) | 2011-10-04 |
| AR057964A1 (es) | 2007-12-26 |
| IL191971A0 (en) | 2011-08-01 |
| PT1963302E (pt) | 2013-04-09 |
| ZA200804374B (en) | 2009-12-30 |
| CA2632283A1 (en) | 2007-06-14 |
| AU2006323025B2 (en) | 2012-07-05 |
| WO2007066185A3 (en) | 2008-01-24 |
| IL191971A (en) | 2013-05-30 |
| TWI389902B (zh) | 2013-03-21 |
| KR20080074950A (ko) | 2008-08-13 |
| JP4663619B2 (ja) | 2011-04-06 |
| RU2387650C2 (ru) | 2010-04-27 |
| SI1963302T1 (sl) | 2013-04-30 |
| TW200730522A (en) | 2007-08-16 |
| CN101326175A (zh) | 2008-12-17 |
| WO2007066185A2 (en) | 2007-06-14 |
| AU2006323025A1 (en) | 2007-06-14 |
| CA2632283C (en) | 2011-06-21 |
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