AR015769A1 - Derivados de imidazo piridina que inhiben la secrecion de acido gastrico, procedimiento para la preparacion de dichos derivados, composicion farmaceutica, uso de dichos derivados para la preparacion de medicamentos, y compuestos intermediarios. - Google Patents
Derivados de imidazo piridina que inhiben la secrecion de acido gastrico, procedimiento para la preparacion de dichos derivados, composicion farmaceutica, uso de dichos derivados para la preparacion de medicamentos, y compuestos intermediarios.Info
- Publication number
- AR015769A1 AR015769A1 ARP990101777A ARP990101777A AR015769A1 AR 015769 A1 AR015769 A1 AR 015769A1 AR P990101777 A ARP990101777 A AR P990101777A AR P990101777 A ARP990101777 A AR P990101777A AR 015769 A1 AR015769 A1 AR 015769A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- preparation
- alkyl
- medicines
- inhibit
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Derivados de imidazo piridina que comprenden la formula I o una sal farmacéuticamente aceptable del mismo, donde R1 es (a)H, (b)CH3, o (c)CH2OH; R2 es(a)CH3, (b)CH2CH3, R3 es (a)H, (b)alquilo C1-6, (c)alquilo C1-6 hidroxilado, (d)halogeno, R4 es(a)H , (b)alquilo C1-6, (c)alquilo C1-6 hidroxilado, (d)halogenoR5 es (a)H, (d)halogeno, R6, R7 son iguales o diferentes son sustituyentes independientemetne seleccionados, que comprenden átomos de C, H, N, O, S, Se, P yhalogeno, que proporcionancompuest os de formula I de un peso molecular de [600, con la condicion de que por lo menos uno de R6 y R7 no sea H, alquilo C1-6,alquilo C1-6 hidroxilado, o alquilo C1-6 sustituido con alcoxi C1-6 y X es (a)NH, o (b)O; que inhiben en forma exogenao endogena la secrecion estimulada deácido gástrico y que puede usarse por lo tanto para la prevencion y tratamiento de enfermedades inflamatorias intestinales. Productos que los contienen,procedimientos para la preparacion de dichos derivados,formulacion far macéutica, uso de dichos derivados para la preparacion de medicamentos y compuestosintermediarios.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9801526A SE9801526D0 (sv) | 1998-04-29 | 1998-04-29 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR015769A1 true AR015769A1 (es) | 2001-05-16 |
Family
ID=20411154
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990101776A AR015768A1 (es) | 1998-04-29 | 1999-04-16 | DERIVADOS DE IMIDAZO PIRIDINA QUE INHIBEN LA SECRECIoN DE ÁCIDO GÁSTRICO, COMPOSICIoN FARMACÉUTICA, PROCEDIMIENTOS PARA SU PREPARACIoN, FORMULACIoN FARMACÉUTICA, USO DE DICHOS DERIVADOS PARA PREPARAR MEDICAMENTOS Y COMPUESTOS INTERMEDIARIOS uTILES EN EL PROCEDIMIENTO PARA LA PREPARACIoN DE DICHOS DE |
ARP990101777A AR015769A1 (es) | 1998-04-29 | 1999-04-16 | Derivados de imidazo piridina que inhiben la secrecion de acido gastrico, procedimiento para la preparacion de dichos derivados, composicion farmaceutica, uso de dichos derivados para la preparacion de medicamentos, y compuestos intermediarios. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990101776A AR015768A1 (es) | 1998-04-29 | 1999-04-16 | DERIVADOS DE IMIDAZO PIRIDINA QUE INHIBEN LA SECRECIoN DE ÁCIDO GÁSTRICO, COMPOSICIoN FARMACÉUTICA, PROCEDIMIENTOS PARA SU PREPARACIoN, FORMULACIoN FARMACÉUTICA, USO DE DICHOS DERIVADOS PARA PREPARAR MEDICAMENTOS Y COMPUESTOS INTERMEDIARIOS uTILES EN EL PROCEDIMIENTO PARA LA PREPARACIoN DE DICHOS DE |
Country Status (34)
Country | Link |
---|---|
US (2) | US6313136B1 (es) |
EP (4) | EP1491543B1 (es) |
JP (2) | JP3692034B2 (es) |
KR (3) | KR100595806B1 (es) |
CN (2) | CN1174980C (es) |
AR (2) | AR015768A1 (es) |
AT (4) | ATE307130T1 (es) |
AU (2) | AU769108B2 (es) |
BR (2) | BR9909996B1 (es) |
CA (2) | CA2329921A1 (es) |
CZ (2) | CZ293977B6 (es) |
DE (4) | DE69928792T2 (es) |
DK (2) | DK1073657T3 (es) |
EE (2) | EE04676B1 (es) |
ES (2) | ES2249913T3 (es) |
HK (5) | HK1033457A1 (es) |
HU (2) | HUP0102425A3 (es) |
ID (2) | ID26819A (es) |
IL (4) | IL139297A0 (es) |
IS (2) | IS5683A (es) |
MY (2) | MY121389A (es) |
NO (2) | NO318203B1 (es) |
NZ (2) | NZ507639A (es) |
PL (2) | PL195000B1 (es) |
RU (2) | RU2238271C2 (es) |
SA (2) | SA99200065B1 (es) |
SE (1) | SE9801526D0 (es) |
SI (1) | SI1073656T1 (es) |
SK (2) | SK285768B6 (es) |
TR (4) | TR200102612T2 (es) |
TW (2) | TWI250159B (es) |
UA (2) | UA67769C2 (es) |
WO (2) | WO1999055706A1 (es) |
ZA (2) | ZA200005797B (es) |
Families Citing this family (61)
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US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
SE9802794D0 (sv) * | 1998-08-21 | 1998-08-21 | Astra Ab | New compounds |
US6900324B2 (en) | 2000-09-07 | 2005-05-31 | Astrazeneca Ab | Process for preparing a substituted imidazopyridine compound |
SE0003186D0 (sv) * | 2000-09-07 | 2000-09-07 | Astrazeneca Ab | New process |
UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
SE0100296D0 (sv) * | 2001-02-01 | 2001-02-01 | Astrazeneca Ab | New compounds |
SE0100297D0 (sv) * | 2001-02-01 | 2001-02-01 | Astrazeneca Ab | New compounds |
SE0100295D0 (sv) * | 2001-02-01 | 2001-02-01 | Astrazeneca Ab | New compounds |
CA2434835A1 (en) * | 2001-02-13 | 2002-08-22 | Astrazeneca Ab | Novel modified released formulation |
US20040082605A1 (en) * | 2001-03-08 | 2004-04-29 | Arne Eek | Use |
SE0102808D0 (sv) * | 2001-08-22 | 2001-08-22 | Astrazeneca Ab | New compounds |
MY140561A (en) * | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
SE0201939D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination |
SE0201940D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination II |
KR20050052500A (ko) | 2002-09-19 | 2005-06-02 | 쉐링 코포레이션 | 사이클린 의존성 키나제 억제제로서의 이미다조피리딘 |
JP2006508142A (ja) | 2002-11-19 | 2006-03-09 | アルタナ ファルマ アクチエンゲゼルシャフト | 8−置換イミダゾピリジン |
AR043002A1 (es) * | 2003-02-18 | 2005-07-13 | Altana Pharma Ag | Imidazopirazinas 6-substituidos |
NZ541861A (en) * | 2003-02-26 | 2009-05-31 | Sugen Inc | Aminoheteroaryl compounds as protein kinase inhibitors |
US7470791B2 (en) | 2003-03-10 | 2008-12-30 | Nycomed Gmbh | Process for the preparation of roflumilast |
SE525349C2 (sv) * | 2003-06-23 | 2005-02-08 | Volvo Penta Ab | Utombordsdrev för båtar |
SE0301903D0 (sv) * | 2003-06-26 | 2003-06-26 | Astrazeneca Ab | Novel imidazopyridine compound III with therapeutic effect |
SE0301905D0 (sv) * | 2003-06-26 | 2003-06-26 | Astrazeneca Ab | Novel imidazopyridine compound I with therapeutic effect |
SE0301904D0 (sv) * | 2003-06-26 | 2003-06-26 | Astrazeneca Ab | Novel imidazopyridine compound II with therapeutic effect |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
EP1974730A1 (en) | 2003-11-03 | 2008-10-01 | AstraZeneca AB | Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux |
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WO2005070927A2 (en) * | 2004-01-26 | 2005-08-04 | Altana Pharma Ag | 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors |
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NZ568654A (en) * | 2005-12-05 | 2012-02-24 | Pfizer Prod Inc | Method of treating abnormal cell growth |
PT1963302E (pt) * | 2005-12-05 | 2013-04-09 | Pfizer Prod Inc | Polimorfos de um inibidor de c-met/hgfr |
WO2007107827A1 (en) * | 2006-03-17 | 2007-09-27 | Raqualia Pharma Inc. | Chromane derivatives |
WO2008013785A2 (en) | 2006-07-24 | 2008-01-31 | Singh-Broemer And Company, Inc. | Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening |
WO2008059373A1 (es) * | 2006-11-17 | 2008-05-22 | Raqualia Pharma Inc. | Vacuna contra la malaria, basada en la subunidad 200l de la proteína msp1 de plasmodium vivax. |
EP1974729A1 (en) * | 2007-03-28 | 2008-10-01 | Santhera Pharmaceuticals (Schweiz) AG | Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists |
WO2009122435A2 (en) * | 2008-03-31 | 2009-10-08 | Council Of Scientific & Industrial Research | A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine |
AU2014201644B2 (en) * | 2008-12-03 | 2015-05-21 | Cinclus Pharma Holding AB (publ) | Imidazopyridine derivatives which inhibit the secretion of gastric acid |
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KR20190057569A (ko) * | 2017-11-20 | 2019-05-29 | 제일약품주식회사 | 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도 |
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JP7353295B2 (ja) * | 2018-04-10 | 2023-09-29 | バイエル・アクチエンゲゼルシヤフト | 2,6-ジアルキルフェニル酢酸の製造方法 |
RU2732297C2 (ru) * | 2018-11-14 | 2020-09-15 | Общество с ограниченной ответственностью "Гурус БиоФарм" | Производные нестероидных противовоспалительных средств |
AU2020377451A1 (en) | 2019-11-04 | 2022-05-26 | Cinclus Pharma Holding AB | Oral formulation of X842 |
MX2024005463A (es) | 2021-11-05 | 2024-05-22 | Cinclus Pharma Holding Ab Publ | Polimorfos de la sal de mesilato de glurato de linaprazan. |
IL312564A (en) | 2021-11-05 | 2024-07-01 | Cinclus Pharma Holding Ab Publ | Polymorphs of the hydrochloride salt of linfarezan glurate |
KR102496869B1 (ko) * | 2022-07-29 | 2023-02-07 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법 |
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ZA81219B (en) * | 1980-01-23 | 1982-01-27 | Schering Corp | Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them |
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1998
- 1998-04-29 SE SE9801526A patent/SE9801526D0/xx unknown
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1999
- 1999-04-16 TW TW088106128A patent/TWI250159B/zh not_active IP Right Cessation
- 1999-04-16 AR ARP990101776A patent/AR015768A1/es active IP Right Grant
- 1999-04-16 AR ARP990101777A patent/AR015769A1/es active IP Right Grant
- 1999-04-16 TW TW088106129A patent/TW490466B/zh not_active IP Right Cessation
- 1999-04-23 TR TR2001/02612T patent/TR200102612T2/xx unknown
- 1999-04-23 DE DE69928792T patent/DE69928792T2/de not_active Expired - Lifetime
- 1999-04-23 BR BRPI9909996-9A patent/BR9909996B1/pt not_active IP Right Cessation
- 1999-04-23 NZ NZ507639A patent/NZ507639A/en unknown
- 1999-04-23 CN CNB998077992A patent/CN1174980C/zh not_active Expired - Fee Related
- 1999-04-23 CZ CZ20003981A patent/CZ293977B6/cs not_active IP Right Cessation
- 1999-04-23 AT AT99947037T patent/ATE307130T1/de not_active IP Right Cessation
- 1999-04-23 HU HU0102425A patent/HUP0102425A3/hu unknown
- 1999-04-23 DE DE69937077T patent/DE69937077T2/de not_active Expired - Lifetime
- 1999-04-23 WO PCT/SE1999/000663 patent/WO1999055706A1/en not_active Application Discontinuation
- 1999-04-23 TR TR2000/03176T patent/TR200003176T2/xx unknown
- 1999-04-23 ES ES99947037T patent/ES2249913T3/es not_active Expired - Lifetime
- 1999-04-23 DK DK99947038T patent/DK1073657T3/da active
- 1999-04-23 CN CNB998078026A patent/CN1165535C/zh not_active Expired - Fee Related
- 1999-04-23 NZ NZ507638A patent/NZ507638A/en unknown
- 1999-04-23 EE EEP200000626A patent/EE04676B1/xx not_active IP Right Cessation
- 1999-04-23 US US09/319,890 patent/US6313136B1/en not_active Expired - Fee Related
- 1999-04-23 HU HU0102313A patent/HUP0102313A3/hu unknown
- 1999-04-23 ID IDW20002206A patent/ID26819A/id unknown
- 1999-04-23 EP EP04023091A patent/EP1491543B1/en not_active Expired - Lifetime
- 1999-04-23 KR KR1020007012027A patent/KR100595806B1/ko not_active IP Right Cessation
- 1999-04-23 IL IL13929799A patent/IL139297A0/xx active IP Right Grant
- 1999-04-23 AU AU43006/99A patent/AU769108B2/en not_active Ceased
- 1999-04-23 WO PCT/SE1999/000662 patent/WO1999055705A1/en not_active Application Discontinuation
- 1999-04-23 JP JP2000545865A patent/JP3692034B2/ja not_active Expired - Fee Related
- 1999-04-23 DE DE69937076T patent/DE69937076T2/de not_active Expired - Lifetime
- 1999-04-23 RU RU2000127019/04A patent/RU2238271C2/ru active
- 1999-04-23 SK SK1492-2000A patent/SK285768B6/sk not_active IP Right Cessation
- 1999-04-23 TR TR2000/03149T patent/TR200003149T2/xx unknown
- 1999-04-23 SI SI9930850T patent/SI1073656T1/sl unknown
- 1999-04-23 DK DK99947037T patent/DK1073656T3/da active
- 1999-04-23 AT AT99947038T patent/ATE312101T1/de not_active IP Right Cessation
- 1999-04-23 US US09/319,973 patent/US6313137B1/en not_active Expired - Fee Related
- 1999-04-23 UA UA2000106033A patent/UA67769C2/uk unknown
- 1999-04-23 CA CA002329921A patent/CA2329921A1/en not_active Abandoned
- 1999-04-23 KR KR1020007012028A patent/KR100650472B1/ko not_active IP Right Cessation
- 1999-04-23 PL PL343801A patent/PL195000B1/pl not_active IP Right Cessation
- 1999-04-23 KR KR1020057022787A patent/KR100595805B1/ko not_active IP Right Cessation
- 1999-04-23 EP EP99947037A patent/EP1073656B1/en not_active Expired - Lifetime
- 1999-04-23 EP EP99947038A patent/EP1073657B1/en not_active Expired - Lifetime
- 1999-04-23 CZ CZ20003982A patent/CZ292567B6/cs not_active IP Right Cessation
- 1999-04-23 DE DE69927803T patent/DE69927803T2/de not_active Expired - Lifetime
- 1999-04-23 AT AT04023090T patent/ATE372339T1/de not_active IP Right Cessation
- 1999-04-23 JP JP2000545864A patent/JP3883383B2/ja not_active Expired - Fee Related
- 1999-04-23 BR BRPI9909995-0A patent/BR9909995B1/pt not_active IP Right Cessation
- 1999-04-23 PL PL99343797A patent/PL343797A1/xx unknown
- 1999-04-23 ID IDW20002205A patent/ID27530A/id unknown
- 1999-04-23 EP EP04023090A patent/EP1491542B1/en not_active Expired - Lifetime
- 1999-04-23 IL IL13920099A patent/IL139200A0/xx unknown
- 1999-04-23 UA UA2000106034A patent/UA66846C2/uk unknown
- 1999-04-23 AT AT04023091T patent/ATE372340T1/de not_active IP Right Cessation
- 1999-04-23 AU AU43007/99A patent/AU769190B2/en not_active Ceased
- 1999-04-23 CA CA002329922A patent/CA2329922C/en not_active Expired - Fee Related
- 1999-04-23 TR TR2001/02728T patent/TR200102728T2/xx unknown
- 1999-04-23 RU RU2000127020/04A patent/RU2235725C2/ru active
- 1999-04-23 SK SK1491-2000A patent/SK14912000A3/sk unknown
- 1999-04-23 ES ES99947038T patent/ES2252975T3/es not_active Expired - Lifetime
- 1999-04-23 EE EEP200000664A patent/EE04916B1/xx not_active IP Right Cessation
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- 1999-05-01 SA SA99200065A patent/SA99200065B1/ar unknown
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2000
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2001
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