EE200000626A - Imidasopüridiini derivaadid, mis inhibeerivad maohappesekretsiooni - Google Patents

Imidasopüridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Info

Publication number
EE200000626A
EE200000626A EEP200000626A EEP200000626A EE200000626A EE 200000626 A EE200000626 A EE 200000626A EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 200000626 A EE200000626 A EE 200000626A
Authority
EE
Estonia
Prior art keywords
gastric acid
acid secretion
imidazopyridine derivatives
inhibit gastric
inhibit
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/et
Publication of EE04676B1 publication Critical patent/EE04676B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A true EE200000626A (et) 2002-04-15
EE04676B1 EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (34)

Country Link
US (2) US6313137B1 (et)
EP (4) EP1491542B1 (et)
JP (2) JP3692034B2 (et)
KR (3) KR100650472B1 (et)
CN (2) CN1174980C (et)
AR (2) AR015768A1 (et)
AT (4) ATE312101T1 (et)
AU (2) AU769190B2 (et)
BR (2) BR9909995B1 (et)
CA (2) CA2329921A1 (et)
CZ (2) CZ292567B6 (et)
DE (4) DE69937076T2 (et)
DK (2) DK1073657T3 (et)
EE (2) EE04676B1 (et)
ES (2) ES2252975T3 (et)
HK (5) HK1033457A1 (et)
HU (2) HUP0102313A3 (et)
ID (2) ID27530A (et)
IL (4) IL139200A0 (et)
IS (2) IS5683A (et)
MY (2) MY121389A (et)
NO (2) NO318203B1 (et)
NZ (2) NZ507638A (et)
PL (2) PL195000B1 (et)
RU (2) RU2238271C2 (et)
SA (2) SA99200065B1 (et)
SE (1) SE9801526D0 (et)
SI (1) SI1073656T1 (et)
SK (2) SK14912000A3 (et)
TR (4) TR200102612T2 (et)
TW (2) TWI250159B (et)
UA (2) UA66846C2 (et)
WO (2) WO1999055706A1 (et)
ZA (2) ZA200005796B (et)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
NZ526993A (en) * 2001-02-13 2005-01-28 Astrazeneca Ab Pharmaceutical formulation of a drug substance that has a pH-dependent solubility in water
JP2004520422A (ja) * 2001-03-08 2004-07-08 アストラゼネカ・アクチエボラーグ 新しい用途
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
US6992080B2 (en) 2002-09-19 2006-01-31 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
JP2006508142A (ja) 2002-11-19 2006-03-09 アルタナ　ファルマ　アクチエンゲゼルシャフト ８−置換イミダゾピリジン
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
CN103265477B (zh) * 2003-02-26 2017-01-11 苏根公司 作为蛋白激酶抑制剂的氨基杂芳基化合物
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AP2007004023A0 (en) * 2004-12-17 2007-06-30 Pfizer Chromane derivatives useful as acid pump antagonists
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
KR101300831B1 (ko) * 2005-03-21 2013-08-30 에스*바이오 피티이 리미티드 이미다조[1,2-ａ]피리딘 유도체, 이의 제조 방법 및 그의약학적 용도
TW200700064A (en) * 2005-03-24 2007-01-01 Glaxo Group Ltd Novel compounds
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007066185A2 (en) 2005-12-05 2007-06-14 Pfizer Products Inc. Polymorphs of a c-met/hgfr inhibitor
SI1959955T1 (sl) * 2005-12-05 2011-02-28 Pfizer Prod Inc Postopek zdravljenja abnormalne celične rasti
KR20080108129A (ko) * 2006-03-17 2008-12-11 라퀄리아 파마 인코포레이티드 크로메인 유도체
EP2054036B1 (en) 2006-07-24 2019-12-18 Singh-Broemer and Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
WO2009122435A2 (en) * 2008-03-31 2009-10-08 Council Of Scientific & Industrial Research A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
WO2011004882A1 (ja) * 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
CN105358151B (zh) * 2013-06-25 2019-04-12 豪夫迈·罗氏有限公司 用于治疗脊髓性肌萎缩的化合物
AU2014365823B2 (en) 2013-12-16 2019-05-02 Abs Development 1, Inc. P2X3 and/or P2X2/3 compounds and methods
JP6578298B2 (ja) * 2014-03-24 2019-09-18 アークル インコーポレイテッド ３−（３−（４−（１−アミノシクロブチル）フェニル）−５−フェニル−３ｈ−イミダゾ［４，５−ｂ］ピリジン−２−イル）ピリジン−２−アミンを調製する方法
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
WO2019152977A2 (en) 2018-02-05 2019-08-08 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
WO2019197232A1 (de) * 2018-04-10 2019-10-17 Bayer Aktiengesellschaft Verfahren zur herstellung von 2,6-dialkylphenyl-essigsäuren
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
KR20220097431A (ko) 2019-11-04 2022-07-07 싱클루스 파마 홀딩 에이비 X842의 경구용 제제
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
CN118201927A (zh) 2021-11-05 2024-06-14 辛克鲁斯制药控股有限公司(Publ) 戊二酸利那拉赞的盐酸盐的多晶型物
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
CN1307577A (zh) 2001-08-08
CA2329922A1 (en) 1999-11-04
BR9909995A (pt) 2000-12-26
CZ292567B6 (cs) 2003-10-15
AU4300799A (en) 1999-11-16
TW490466B (en) 2002-06-11
EP1073656A1 (en) 2001-02-07
UA67769C2 (uk) 2004-07-15
BR9909995B1 (pt) 2010-07-13
CZ293977B6 (cs) 2004-09-15
HUP0102313A2 (hu) 2001-12-28
DE69937077T2 (de) 2008-05-29
KR100595806B1 (ko) 2006-07-03
TR200102728T2 (tr) 2002-06-21
DE69927803D1 (de) 2006-03-02
AR015768A1 (es) 2001-05-16
JP2002513024A (ja) 2002-05-08
DE69928792D1 (de) 2006-01-12
NO20005450D0 (no) 2000-10-27
TR200102612T2 (tr) 2002-06-21
TWI250159B (en) 2006-03-01
SE9801526D0 (sv) 1998-04-29
JP2002513025A (ja) 2002-05-08
NZ507639A (en) 2004-01-30
TR200003149T2 (tr) 2001-03-21
CA2329922C (en) 2006-04-11
AU769108B2 (en) 2004-01-15
HK1071139A1 (en) 2005-07-08
CZ20003982A3 (cs) 2001-02-14
AR015769A1 (es) 2001-05-16
EE04676B1 (et) 2006-08-15
PL195000B1 (pl) 2007-07-31
HK1033317A1 (en) 2001-08-24
HUP0102425A2 (hu) 2001-11-28
IL139200A (en) 2010-04-29
KR100595805B1 (ko) 2006-07-03
SA99200064B1 (ar) 2006-10-11
WO1999055706A9 (en) 2000-03-16
KR20010043133A (ko) 2001-05-25
ATE312101T1 (de) 2005-12-15
US6313136B1 (en) 2001-11-06
ES2249913T3 (es) 2006-04-01
RU2238271C2 (ru) 2004-10-20
JP3692034B2 (ja) 2005-09-07
DE69937076T2 (de) 2008-05-29
CN1174980C (zh) 2004-11-10
IL139200A0 (en) 2001-11-25
DK1073656T3 (da) 2006-01-16
AU769190B2 (en) 2004-01-22
PL343797A1 (en) 2001-09-10
HK1033457A1 (en) 2001-08-31
KR100650472B1 (ko) 2006-11-28
CZ20003981A3 (cs) 2001-03-14
ATE372340T1 (de) 2007-09-15
DE69937077D1 (de) 2007-10-18
TR200003176T2 (tr) 2001-03-21
HUP0102313A3 (en) 2002-10-28
CN1306533A (zh) 2001-08-01
HUP0102425A3 (en) 2002-12-28
DE69927803T2 (de) 2006-07-06
EP1491543A1 (en) 2004-12-29
EP1073657A1 (en) 2001-02-07
MY121389A (en) 2006-01-28
JP3883383B2 (ja) 2007-02-21
IS5684A (is) 2000-10-25
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
BR9909996B1 (pt) 2010-08-24
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
HK1036981A1 (en) 2002-01-25
UA66846C2 (uk) 2004-06-15
PL343801A1 (en) 2001-09-10
NO20005451D0 (no) 2000-10-27
ES2252975T3 (es) 2006-05-16
IL139297A (en) 2007-06-03
HK1036984A1 (en) 2002-01-25
US6313137B1 (en) 2001-11-06
WO1999055705A1 (en) 1999-11-04
NO20005450L (no) 2000-12-22
KR20050121760A (ko) 2005-12-27
NO317262B1 (no) 2004-09-27
ATE307130T1 (de) 2005-11-15
KR20010043134A (ko) 2001-05-25
NZ507638A (en) 2003-10-31
EP1073657B1 (en) 2005-12-07
ID27530A (id) 2001-04-12
SK14912000A3 (sk) 2001-06-11
CN1165535C (zh) 2004-09-08
ID26819A (id) 2001-02-15
SA99200065B1 (ar) 2006-11-07
SK14922000A3 (sk) 2001-06-11
BR9909996A (pt) 2000-12-26
EE04916B1 (et) 2007-10-15
ZA200005796B (en) 2002-01-18
SK285768B6 (sk) 2007-07-06
NO20005451L (no) 2000-12-27
AU4300699A (en) 1999-11-16
EP1073656B1 (en) 2005-10-19
CA2329921A1 (en) 1999-11-04
SA99200065A (ar) 2005-12-03
EP1491543B1 (en) 2007-09-05
ATE372339T1 (de) 2007-09-15
NO318203B1 (no) 2005-02-14
EP1491542A3 (en) 2005-01-05
IL139297A0 (en) 2001-11-25
IS5683A (is) 2000-10-25
MY121379A (en) 2006-01-28
DE69928792T2 (de) 2006-07-20
DE69937076D1 (de) 2007-10-18
DK1073657T3 (da) 2006-03-13
ZA200005797B (en) 2002-01-18
RU2235725C2 (ru) 2004-09-10
EP1491542A2 (en) 2004-12-29

Similar Documents

Publication Publication Date Title
EE200000664A (et) Imidasopüridiini derivaadid, mis inhibeerivad maohappesekretsiooni
IT1312018B1 (it) Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina.
ATE305470T1 (de) Naphthyridinverbindungen
EE04016B1 (et) Ühendid maohappesekretsiooni inhibeerimiseks
NO20004722L (no) Faste, hurtigdesintegrerende cetirizin-formuleringer
MX234484B (es) Aditivo de cemento.
IT1317741B1 (it) Metodo per la preparazione di 5-cianoftalide.
IT1319251B1 (it) Metodo per la preparazione di 5-carbossiftalide.
NO20031830D0 (no) Polysubstituerte imidazopyridiner som gastriske sekresjonshemmere
ATE309220T1 (de) Substituierte 1,2,3,4-tetrahydrochinolin-2- carbonsäurederivate
EE200200204A (et) Asendatud bensimidasooli preparaat
ZA200110127B (en) Substituted benzimidazole.
ZA200006045B (en) Gastric acid secretion.
NO20020485D0 (no) Heterocykliske forbindelser som inhiberer angiogenese
PL358585A1 (en) N-substituted-1-amino-1,1-dialkylcarboxylic acid derivatives
SI1073657T1 (sl) Imidazo piridinski derivati, ki inhibirajo izlocanje zelodcne kisline
IT1312000B1 (it) Procedimento per la preparazione di composti semiconduttori.
ITBO990455A1 (it) Corpo nudo di fantocci per bambini .
ITTS990002A3 (it) Progetto rem
ITTS990003U3 (it) Progetto rem
ITRM20000199A0 (it) Formulazione.
IT1307914B1 (it) Apparecchiatura per la produzione di yogurt.

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20100423