BR9712058B1 - formulações para uso de ivermectina, processo para sua preparação e uso. - Google Patents

formulações para uso de ivermectina, processo para sua preparação e uso.

Info

Publication number
BR9712058B1
BR9712058B1 BRPI9712058-8A BR9712058A BR9712058B1 BR 9712058 B1 BR9712058 B1 BR 9712058B1 BR 9712058 A BR9712058 A BR 9712058A BR 9712058 B1 BR9712058 B1 BR 9712058B1
Authority
BR
Brazil
Prior art keywords
ivermectin
formulations
preparation
Prior art date
Application number
BRPI9712058-8A
Other languages
English (en)
Other versions
BR9712058A (pt
Inventor
Michael Dr Grosse-Bley
Richard Dr Kujanek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to BRPI9715298A priority Critical patent/BRPI9715298B8/pt
Publication of BR9712058A publication Critical patent/BR9712058A/pt
Publication of BR9712058B1 publication Critical patent/BR9712058B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
BRPI9712058-8A 1996-09-18 1997-09-08 formulações para uso de ivermectina, processo para sua preparação e uso. BR9712058B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI9715298A BRPI9715298B8 (pt) 1996-09-18 1997-09-08 formulações para injeção de avermectinas ou milbemicinas para uso veterinário, processo para sua preparação e uso

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19638045A DE19638045A1 (de) 1996-09-18 1996-09-18 Injektionsformulierungen von Avermectinen und Milbemycinen
PCT/EP1997/004867 WO1998011902A1 (de) 1996-09-18 1997-09-08 Injektionsformulierungen von avermectinen und milbemycinen

Publications (2)

Publication Number Publication Date
BR9712058A BR9712058A (pt) 1999-08-24
BR9712058B1 true BR9712058B1 (pt) 2009-05-05

Family

ID=7806009

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9712058-8A BR9712058B1 (pt) 1996-09-18 1997-09-08 formulações para uso de ivermectina, processo para sua preparação e uso.
BRPI9715298A BRPI9715298B8 (pt) 1996-09-18 1997-09-08 formulações para injeção de avermectinas ou milbemicinas para uso veterinário, processo para sua preparação e uso

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI9715298A BRPI9715298B8 (pt) 1996-09-18 1997-09-08 formulações para injeção de avermectinas ou milbemicinas para uso veterinário, processo para sua preparação e uso

Country Status (18)

Country Link
US (1) US6617314B2 (pt)
EP (1) EP0939638B1 (pt)
JP (1) JP4822196B2 (pt)
KR (1) KR20000035978A (pt)
CN (1) CN1130203C (pt)
AR (1) AR008844A1 (pt)
AT (1) ATE228845T1 (pt)
AU (1) AU750874B2 (pt)
BR (2) BR9712058B1 (pt)
CA (1) CA2265952C (pt)
DE (2) DE19638045A1 (pt)
DK (1) DK0939638T3 (pt)
ES (1) ES2184135T3 (pt)
HK (1) HK1022845A1 (pt)
NZ (1) NZ334673A (pt)
PL (1) PL332137A1 (pt)
WO (1) WO1998011902A1 (pt)
ZA (1) ZA978352B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
KR20000025762A (ko) * 1998-10-14 2000-05-06 유충식 이버멕틴류의 가용화 조성물
GB9827727D0 (en) * 1998-12-16 1999-02-10 Pfizer Ltd Antiparasitic formulations
GB0000313D0 (en) 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
AU781682B2 (en) * 2000-03-20 2005-06-09 Zoetis Services Llc Sustained-release compositions for parenteral administration
US6872708B2 (en) * 2001-09-10 2005-03-29 Mitsukazu Matsumoto Local injection prescription
US7396819B2 (en) * 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
US7582612B2 (en) 2004-03-12 2009-09-01 Hartz Mountain Corporation Multi-action anthelmintic formulations
NZ590141A (en) * 2008-06-24 2012-05-25 Merial Ltd Anthelminthic formulations including castor oil and another vegetable oil
CA2750626C (en) * 2009-02-16 2013-10-01 Pfizer Inc. High dosage doramectin formulation
CN101773467B (zh) * 2010-01-20 2015-09-09 北京大北农动物保健科技有限责任公司 一种美贝霉素或美贝霉素肟的兽用缓释注射液及制备方法
US20110223208A1 (en) * 2010-03-09 2011-09-15 Beth Hill Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations
US9072668B2 (en) 2010-03-09 2015-07-07 Janssen Biotech, Inc. Non-aqueous high concentration reduced viscosity suspension formulations of antibodies
WO2011112669A1 (en) * 2010-03-09 2011-09-15 Centocor Ortho Biotech Inc. Non-aqueous high concentration reduced viscosity suspension formulations
CA2867079A1 (en) 2012-03-13 2013-09-19 Bayer New Zealand Limited Long acting compositions
CN103417478B (zh) * 2012-05-18 2014-09-10 中国农业科学院兰州畜牧与兽药研究所 一种以水为基质的伊维菌素o/w型注射液及其制备方法
WO2017119928A1 (en) * 2016-01-08 2017-07-13 Abon Pharmaceuticals, Llc Long acting injectable formulations
US20210137960A1 (en) 2018-02-01 2021-05-13 Yale University Compositions and methods for inhibition of nuclear-penetrating antibodies
CN114107097B (zh) * 2021-11-10 2024-03-05 河北兴柏农业科技股份有限公司 一种阿佛曼链霉菌活性孢子的固体发酵工艺

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA06863A (fr) * 1980-08-04 1983-02-28 Merck & Co Inc Solubilisation de l'invermectine dans l'eau.
NZ210505A (en) * 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
EP0393890B1 (en) * 1989-04-11 1992-08-12 Pfizer Limited Injectable compositions containing 25-cyclohexyl-avermectin b1
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
NZ234802A (en) * 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US5055486A (en) 1989-12-22 1991-10-08 American Cyanamid Company 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5030650A (en) 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
DE69208765T2 (de) * 1991-07-23 1996-09-26 American Cyanamid Co Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
ES2131515T3 (es) * 1991-09-30 1999-08-01 Merck & Co Inc Formulados inyectables de accion prolongada que contienen aceite de ricino hidrogenado.
GB2275193A (en) * 1993-02-17 1994-08-24 Merck & Co Inc Formulations for the topical delivery of avermectins
DE4443888A1 (de) * 1994-12-09 1996-06-13 Bayer Ag Dermal applizierbare Formulierungen von Parasitiziden
DE69636706T2 (de) * 1995-09-25 2007-10-11 Ashmont Holdings Ltd., Takapuna Makrocyclische lacton anthelmintika
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
RU2140737C1 (ru) * 1998-09-22 1999-11-10 Мосин Владимир Александрович Средство для профилактики и лечения паразитарных заболеваний животных
CN1219393A (zh) * 1998-11-13 1999-06-16 王玉万 一种含阿维菌素或伊维菌素的兽用抗寄生虫油剂口服液及其制备方法

Also Published As

Publication number Publication date
DE19638045A1 (de) 1998-03-19
ZA978352B (en) 1998-03-24
ES2184135T3 (es) 2003-04-01
HK1022845A1 (en) 2000-08-25
JP2001503029A (ja) 2001-03-06
CN1230890A (zh) 1999-10-06
ATE228845T1 (de) 2002-12-15
US6617314B2 (en) 2003-09-09
EP0939638A1 (de) 1999-09-08
AU750874B2 (en) 2002-08-01
AU4621597A (en) 1998-04-14
KR20000035978A (ko) 2000-06-26
JP4822196B2 (ja) 2011-11-24
CA2265952A1 (en) 1998-03-26
BRPI9715298B8 (pt) 2016-04-26
EP0939638B1 (de) 2002-12-04
WO1998011902A1 (de) 1998-03-26
CA2265952C (en) 2009-11-17
US20020160967A1 (en) 2002-10-31
AR008844A1 (es) 2000-02-23
DK0939638T3 (da) 2003-03-24
BR9712058A (pt) 1999-08-24
CN1130203C (zh) 2003-12-10
BR9715298B1 (pt) 2014-10-14
DE59708905D1 (de) 2003-01-16
PL332137A1 (en) 1999-08-30
NZ334673A (en) 2000-10-27

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/06/2009, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: BAYER ANIMAL HEALTH GMBH (DE)

Free format text: TRANSFERIDO DE: BAYER AKTIENGESELLSCHAFT

B25A Requested transfer of rights approved

Owner name: BAYER INTELLECTUAL PROPERTY GMBH (DE)

B15K Others concerning applications: alteration of classification

Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: A61K 31/71; A61K 47/10; A61K 47/14; A61K 47/44.

Ipc: A61K 31/7048 (2006.01), A61K 9/00 (2006.01), A61K

Ipc: A61K 31/7048 (2006.01), A61K 9/00 (2006.01), A61K

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 30.06.2019