ZA978352B - Injection formulations of avermectins and milbemycins. - Google Patents
Injection formulations of avermectins and milbemycins.Info
- Publication number
- ZA978352B ZA978352B ZA9708352A ZA978352A ZA978352B ZA 978352 B ZA978352 B ZA 978352B ZA 9708352 A ZA9708352 A ZA 9708352A ZA 978352 A ZA978352 A ZA 978352A ZA 978352 B ZA978352 B ZA 978352B
- Authority
- ZA
- South Africa
- Prior art keywords
- milbemycins
- avermectins
- injection formulations
- formulations
- injection
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19638045A DE19638045A1 (de) | 1996-09-18 | 1996-09-18 | Injektionsformulierungen von Avermectinen und Milbemycinen |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA978352B true ZA978352B (en) | 1998-03-24 |
Family
ID=7806009
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9708352A ZA978352B (en) | 1996-09-18 | 1997-09-17 | Injection formulations of avermectins and milbemycins. |
Country Status (18)
Country | Link |
---|---|
US (1) | US6617314B2 (xx) |
EP (1) | EP0939638B1 (xx) |
JP (1) | JP4822196B2 (xx) |
KR (1) | KR20000035978A (xx) |
CN (1) | CN1130203C (xx) |
AR (1) | AR008844A1 (xx) |
AT (1) | ATE228845T1 (xx) |
AU (1) | AU750874B2 (xx) |
BR (2) | BRPI9715298B8 (xx) |
CA (1) | CA2265952C (xx) |
DE (2) | DE19638045A1 (xx) |
DK (1) | DK0939638T3 (xx) |
ES (1) | ES2184135T3 (xx) |
HK (1) | HK1022845A1 (xx) |
NZ (1) | NZ334673A (xx) |
PL (1) | PL332137A1 (xx) |
WO (1) | WO1998011902A1 (xx) |
ZA (1) | ZA978352B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458373B1 (en) | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
US7030155B2 (en) | 1998-06-05 | 2006-04-18 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
KR20000025762A (ko) * | 1998-10-14 | 2000-05-06 | 유충식 | 이버멕틴류의 가용화 조성물 |
GB9827727D0 (en) * | 1998-12-16 | 1999-02-10 | Pfizer Ltd | Antiparasitic formulations |
GB0000313D0 (en) | 2000-01-10 | 2000-03-01 | Astrazeneca Uk Ltd | Formulation |
AU781682B2 (en) | 2000-03-20 | 2005-06-09 | Zoetis Services Llc | Sustained-release compositions for parenteral administration |
US6872708B2 (en) * | 2001-09-10 | 2005-03-29 | Mitsukazu Matsumoto | Local injection prescription |
US7396819B2 (en) * | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
WO2005094210A2 (en) | 2004-03-12 | 2005-10-13 | The Hartz Mountain Corporation | Multi-action anthelmintic formulations |
NZ590141A (en) * | 2008-06-24 | 2012-05-25 | Merial Ltd | Anthelminthic formulations including castor oil and another vegetable oil |
PL2396006T3 (pl) | 2009-02-16 | 2013-06-28 | Zoetis Llc | Preparat zawierający doramektynę w dużej dawce |
CN101773467B (zh) * | 2010-01-20 | 2015-09-09 | 北京大北农动物保健科技有限责任公司 | 一种美贝霉素或美贝霉素肟的兽用缓释注射液及制备方法 |
CA2792517C (en) * | 2010-03-09 | 2020-03-24 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations |
US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
AU2013201479C1 (en) * | 2012-03-13 | 2017-11-09 | Elanco New Zealand | Long Acting Compositions |
CN103417478B (zh) * | 2012-05-18 | 2014-09-10 | 中国农业科学院兰州畜牧与兽药研究所 | 一种以水为基质的伊维菌素o/w型注射液及其制备方法 |
US20170196802A1 (en) * | 2016-01-08 | 2017-07-13 | Abon Pharmaceuticals, Llc | Long Acting Injectable Formulations |
WO2019152808A1 (en) | 2018-02-01 | 2019-08-08 | Yale University | Compositions and methods for inhibition of nuclear-penetrating antibodies |
CN114107097B (zh) * | 2021-11-10 | 2024-03-05 | 河北兴柏农业科技股份有限公司 | 一种阿佛曼链霉菌活性孢子的固体发酵工艺 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
OA06863A (fr) * | 1980-08-04 | 1983-02-28 | Merck & Co Inc | Solubilisation de l'invermectine dans l'eau. |
NZ210505A (en) * | 1983-12-22 | 1988-06-30 | Merck & Co Inc | Parasiticidal compositions containing avermectin or milbemycin derivatives |
ES2052173T3 (es) * | 1989-04-11 | 1994-07-01 | Pfizer | Composiciones inyectables que contienen 25-cyclohexil-avermectina b1. |
US6001822A (en) * | 1989-04-11 | 1999-12-14 | Pfizer Inc. | Antiparasitic formulations |
NZ234802A (en) * | 1989-08-14 | 1992-11-25 | Merck & Co Inc | Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals |
US5055486A (en) | 1989-12-22 | 1991-10-08 | American Cyanamid Company | 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents |
US5030650A (en) | 1989-09-11 | 1991-07-09 | American Cyanamid Company | 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents |
ES2086022T3 (es) * | 1991-07-23 | 1996-06-16 | American Cyanamid Co | Composiciones estables para administracion parenteral y su uso. |
ATE180671T1 (de) * | 1991-09-30 | 1999-06-15 | Merck & Co Inc | Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe |
GB2275193A (en) * | 1993-02-17 | 1994-08-24 | Merck & Co Inc | Formulations for the topical delivery of avermectins |
DE4443888A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermal applizierbare Formulierungen von Parasitiziden |
WO1997011709A1 (en) * | 1995-09-25 | 1997-04-03 | Ashmont Holdings Limited | Anthelmintic macrocyclic lactone compositions |
DE19613972A1 (de) * | 1996-04-09 | 1997-10-16 | Bayer Ag | Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl |
RU2140737C1 (ru) * | 1998-09-22 | 1999-11-10 | Мосин Владимир Александрович | Средство для профилактики и лечения паразитарных заболеваний животных |
CN1219393A (zh) * | 1998-11-13 | 1999-06-16 | 王玉万 | 一种含阿维菌素或伊维菌素的兽用抗寄生虫油剂口服液及其制备方法 |
-
1996
- 1996-09-18 DE DE19638045A patent/DE19638045A1/de not_active Withdrawn
-
1997
- 1997-09-08 BR BRPI9715298A patent/BRPI9715298B8/pt active IP Right Grant
- 1997-09-08 AU AU46215/97A patent/AU750874B2/en not_active Ceased
- 1997-09-08 NZ NZ334673A patent/NZ334673A/xx not_active IP Right Cessation
- 1997-09-08 KR KR1019997001893A patent/KR20000035978A/ko not_active Application Discontinuation
- 1997-09-08 BR BRPI9712058-8A patent/BR9712058B1/pt not_active IP Right Cessation
- 1997-09-08 AT AT97944849T patent/ATE228845T1/de active
- 1997-09-08 EP EP97944849A patent/EP0939638B1/de not_active Expired - Lifetime
- 1997-09-08 DE DE59708905T patent/DE59708905D1/de not_active Expired - Lifetime
- 1997-09-08 ES ES97944849T patent/ES2184135T3/es not_active Expired - Lifetime
- 1997-09-08 DK DK97944849T patent/DK0939638T3/da active
- 1997-09-08 CA CA002265952A patent/CA2265952C/en not_active Expired - Lifetime
- 1997-09-08 JP JP51423798A patent/JP4822196B2/ja not_active Expired - Fee Related
- 1997-09-08 US US09/254,615 patent/US6617314B2/en not_active Expired - Lifetime
- 1997-09-08 PL PL97332137A patent/PL332137A1/xx unknown
- 1997-09-08 CN CN97198028A patent/CN1130203C/zh not_active Expired - Fee Related
- 1997-09-08 WO PCT/EP1997/004867 patent/WO1998011902A1/de active IP Right Grant
- 1997-09-17 ZA ZA9708352A patent/ZA978352B/xx unknown
- 1997-09-18 AR ARP970104297A patent/AR008844A1/es active IP Right Grant
-
2000
- 2000-03-31 HK HK00101987A patent/HK1022845A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4822196B2 (ja) | 2011-11-24 |
DE19638045A1 (de) | 1998-03-19 |
CN1130203C (zh) | 2003-12-10 |
AU750874B2 (en) | 2002-08-01 |
BR9712058A (pt) | 1999-08-24 |
AU4621597A (en) | 1998-04-14 |
ATE228845T1 (de) | 2002-12-15 |
BR9712058B1 (pt) | 2009-05-05 |
EP0939638A1 (de) | 1999-09-08 |
CA2265952A1 (en) | 1998-03-26 |
US6617314B2 (en) | 2003-09-09 |
ES2184135T3 (es) | 2003-04-01 |
DE59708905D1 (de) | 2003-01-16 |
BR9715298B1 (pt) | 2014-10-14 |
KR20000035978A (ko) | 2000-06-26 |
CA2265952C (en) | 2009-11-17 |
US20020160967A1 (en) | 2002-10-31 |
BRPI9715298B8 (pt) | 2016-04-26 |
EP0939638B1 (de) | 2002-12-04 |
PL332137A1 (en) | 1999-08-30 |
HK1022845A1 (en) | 2000-08-25 |
DK0939638T3 (da) | 2003-03-24 |
CN1230890A (zh) | 1999-10-06 |
JP2001503029A (ja) | 2001-03-06 |
WO1998011902A1 (de) | 1998-03-26 |
AR008844A1 (es) | 2000-02-23 |
NZ334673A (en) | 2000-10-27 |
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