ATE180671T1 - Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe - Google Patents

Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe

Info

Publication number
ATE180671T1
ATE180671T1 AT92202940T AT92202940T ATE180671T1 AT E180671 T1 ATE180671 T1 AT E180671T1 AT 92202940 T AT92202940 T AT 92202940T AT 92202940 T AT92202940 T AT 92202940T AT E180671 T1 ATE180671 T1 AT E180671T1
Authority
AT
Austria
Prior art keywords
injectable formulations
oil
cascin
hydrated
extended
Prior art date
Application number
AT92202940T
Other languages
English (en)
Inventor
Elinor H Chen
James B Williams
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE180671T1 publication Critical patent/ATE180671T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
AT92202940T 1991-09-30 1992-09-24 Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe ATE180671T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76879791A 1991-09-30 1991-09-30

Publications (1)

Publication Number Publication Date
ATE180671T1 true ATE180671T1 (de) 1999-06-15

Family

ID=25083508

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92202940T ATE180671T1 (de) 1991-09-30 1992-09-24 Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe

Country Status (10)

Country Link
EP (1) EP0535734B1 (de)
JP (1) JPH0672108B2 (de)
AT (1) ATE180671T1 (de)
AU (1) AU2603792A (de)
CA (1) CA2079255A1 (de)
DE (1) DE69229318T2 (de)
DK (1) DK0535734T3 (de)
ES (1) ES2131515T3 (de)
GR (1) GR3030403T3 (de)
ZA (1) ZA927457B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9300883D0 (en) * 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5981500A (en) * 1994-01-12 1999-11-09 Pfizer Inc. Antiparasitic agents related to the milbemycins and avermectins
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen
WO1999027906A1 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated castor oil
US6174540B1 (en) 1998-09-14 2001-01-16 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated caster oil
GB9827727D0 (en) 1998-12-16 1999-02-10 Pfizer Ltd Antiparasitic formulations
KR100355116B1 (ko) * 2000-02-17 2002-10-11 주식회사 엘지씨아이 애버멕틴 유도체를 포함하는 기생충 박멸용 사료 프레믹스조성물 및 그 제조방법
KR20020067781A (ko) * 2001-02-19 2002-08-24 주식회사 엘지씨아이 구충용 이버멕틴 주사제 조성물 및 그 제조방법
US6653288B1 (en) 2002-09-30 2003-11-25 Virbac S.A. Injectable anthelmintic compositions and methods for using same
WO2004045581A1 (fr) * 2002-11-18 2004-06-03 Yuwan Wang Injection d'une suspension d'un antiparasite veterinaire
US7648711B2 (en) * 2003-05-25 2010-01-19 Yuwan Wang Dimethicone-containing sustained release injection formulation
WO2005084688A1 (fr) * 2004-03-04 2005-09-15 Yuwan Wang Poudre injectable contenant un vermifuge
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
EP2825154A4 (de) * 2012-03-13 2015-11-11 Bayer New Zealand Ltd Lang wirkende zusammensetzungen
CN103705445A (zh) * 2014-01-06 2014-04-09 王玉万 含乙酰甲喹/氢化蓖麻油的原位胶凝注射剂
CN103721266A (zh) * 2014-01-06 2014-04-16 王玉万 含阿维菌素类药物/氢化蓖麻油的原位胶凝注射剂
CN113563395B (zh) * 2021-08-09 2023-06-02 河北威远生物化工有限公司 一种阿维菌素b2衍生物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
NZ234802A (en) * 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals

Also Published As

Publication number Publication date
JPH0672108B2 (ja) 1994-09-14
EP0535734A1 (de) 1993-04-07
EP0535734B1 (de) 1999-06-02
ZA927457B (en) 1993-04-07
CA2079255A1 (en) 1993-03-31
GR3030403T3 (en) 1999-09-30
DE69229318T2 (de) 1999-11-18
DE69229318D1 (de) 1999-07-08
ES2131515T3 (es) 1999-08-01
DK0535734T3 (da) 1999-08-09
AU2603792A (en) 1993-04-01
JPH05246893A (ja) 1993-09-24

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Legal Events

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UEP Publication of translation of european patent specification