ZA927457B - Long acting injectable formulations containing hydrogenated castor oil. - Google Patents
Long acting injectable formulations containing hydrogenated castor oil. Download PDFInfo
- Publication number
- ZA927457B ZA927457B ZA927457A ZA927457A ZA927457B ZA 927457 B ZA927457 B ZA 927457B ZA 927457 A ZA927457 A ZA 927457A ZA 927457 A ZA927457 A ZA 927457A ZA 927457 B ZA927457 B ZA 927457B
- Authority
- ZA
- South Africa
- Prior art keywords
- fot
- bee
- fad
- see
- oer
- Prior art date
Links
- 239000004359 castor oil Substances 0.000 title abstract 3
- 235000019438 castor oil Nutrition 0.000 title abstract 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 title abstract 3
- 239000007972 injectable composition Substances 0.000 title abstract 3
- 241000220317 Rosa Species 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims 2
- CKPWHLGHHXSVJI-UHFFFAOYSA-N 3-fluoroethamphetamine Chemical compound CCNC(C)CC1=CC=CC(F)=C1 CKPWHLGHHXSVJI-UHFFFAOYSA-N 0.000 claims 1
- 101100276977 Caenorhabditis elegans dapk-1 gene Proteins 0.000 claims 1
- 101100373139 Caenorhabditis elegans mig-14 gene Proteins 0.000 claims 1
- 101150034459 Parpbp gene Proteins 0.000 claims 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims 1
- 244000046052 Phaseolus vulgaris Species 0.000 claims 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- 239000004576 sand Substances 0.000 claims 1
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract 3
- 239000005660 Abamectin Substances 0.000 abstract 2
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 avermectin compound Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002687 nonaqueous vehicle Substances 0.000 abstract 1
- 210000002683 foot Anatomy 0.000 description 7
- 101001091379 Homo sapiens Kallikrein-5 Proteins 0.000 description 2
- 241000257303 Hymenoptera Species 0.000 description 2
- 102100034868 Kallikrein-5 Human genes 0.000 description 2
- 102100039028 Protein SPO16 homolog Human genes 0.000 description 2
- 101150108548 SPO16 gene Proteins 0.000 description 2
- 101100020619 Arabidopsis thaliana LATE gene Proteins 0.000 description 1
- 101000608750 Arachis hypogaea Alpha-methyl-mannoside-specific lectin Proteins 0.000 description 1
- 101000916289 Ctenocephalides felis Salivary antigen 1 Proteins 0.000 description 1
- 102000017914 EDNRA Human genes 0.000 description 1
- 101150062404 EDNRA gene Proteins 0.000 description 1
- 240000000731 Fagus sylvatica Species 0.000 description 1
- 235000010099 Fagus sylvatica Nutrition 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 101150094793 Hes3 gene Proteins 0.000 description 1
- 101000941450 Lasioglossum laticeps Lasioglossin-1 Proteins 0.000 description 1
- 101000651848 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Secreted effector protein SseJ Proteins 0.000 description 1
- 101710150104 Sensory rhodopsin-1 Proteins 0.000 description 1
- 101000771730 Tropidolaemus wagleri Waglerin-3 Proteins 0.000 description 1
- 101000870345 Vasconcellea cundinamarcensis Cysteine proteinase 1 Proteins 0.000 description 1
- MUXFZBHBYYYLTH-UHFFFAOYSA-N Zaltoprofen Chemical compound O=C1CC2=CC(C(C(O)=O)C)=CC=C2SC2=CC=CC=C21 MUXFZBHBYYYLTH-UHFFFAOYSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76879791A | 1991-09-30 | 1991-09-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA927457B true ZA927457B (en) | 1993-04-07 |
Family
ID=25083508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA927457A ZA927457B (en) | 1991-09-30 | 1992-09-29 | Long acting injectable formulations containing hydrogenated castor oil. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0535734B1 (de) |
| JP (1) | JPH0672108B2 (de) |
| AT (1) | ATE180671T1 (de) |
| AU (1) | AU2603792A (de) |
| CA (1) | CA2079255A1 (de) |
| DE (1) | DE69229318T2 (de) |
| DK (1) | DK0535734T3 (de) |
| ES (1) | ES2131515T3 (de) |
| GR (1) | GR3030403T3 (de) |
| ZA (1) | ZA927457B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9300883D0 (en) * | 1993-01-18 | 1993-03-10 | Pfizer Ltd | Antiparasitic agents |
| US5981500A (en) * | 1994-01-12 | 1999-11-09 | Pfizer Inc. | Antiparasitic agents related to the milbemycins and avermectins |
| DE19613972A1 (de) * | 1996-04-09 | 1997-10-16 | Bayer Ag | Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl |
| DE19638045A1 (de) * | 1996-09-18 | 1998-03-19 | Bayer Ag | Injektionsformulierungen von Avermectinen und Milbemycinen |
| WO1999027906A1 (en) * | 1997-12-03 | 1999-06-10 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated castor oil |
| US6174540B1 (en) | 1998-09-14 | 2001-01-16 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated caster oil |
| GB9827727D0 (en) | 1998-12-16 | 1999-02-10 | Pfizer Ltd | Antiparasitic formulations |
| KR100355116B1 (ko) * | 2000-02-17 | 2002-10-11 | 주식회사 엘지씨아이 | 애버멕틴 유도체를 포함하는 기생충 박멸용 사료 프레믹스조성물 및 그 제조방법 |
| KR20020067781A (ko) * | 2001-02-19 | 2002-08-24 | 주식회사 엘지씨아이 | 구충용 이버멕틴 주사제 조성물 및 그 제조방법 |
| US6653288B1 (en) | 2002-09-30 | 2003-11-25 | Virbac S.A. | Injectable anthelmintic compositions and methods for using same |
| AU2003234895A1 (en) * | 2002-11-18 | 2004-06-15 | Yuwan Wang | Veterinary antiparasite suspension injection |
| WO2004103343A1 (fr) * | 2003-05-25 | 2004-12-02 | Yuwan Wang | Formulation a liberation prolongee a base de dimethicone |
| WO2005084688A1 (fr) * | 2004-03-04 | 2005-09-15 | Yuwan Wang | Poudre injectable contenant un vermifuge |
| US8362086B2 (en) | 2005-08-19 | 2013-01-29 | Merial Limited | Long acting injectable formulations |
| NZ552040A (en) * | 2006-12-13 | 2009-04-30 | Bomac Research Ltd | Veterinary formulation comprising an anthelmintic compound and glyceryl acetate |
| CN104168886A (zh) * | 2012-03-13 | 2014-11-26 | 拜耳新西兰有限公司 | 长效组合物 |
| CN103705445A (zh) * | 2014-01-06 | 2014-04-09 | 王玉万 | 含乙酰甲喹/氢化蓖麻油的原位胶凝注射剂 |
| CN103721266A (zh) * | 2014-01-06 | 2014-04-16 | 王玉万 | 含阿维菌素类药物/氢化蓖麻油的原位胶凝注射剂 |
| CN113563395B (zh) * | 2021-08-09 | 2023-06-02 | 河北威远生物化工有限公司 | 一种阿维菌素b2衍生物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU596586B2 (en) * | 1985-04-30 | 1990-05-10 | American Cyanamid Company | Chemical derivatives of antibiotics S541 |
| NZ234802A (en) * | 1989-08-14 | 1992-11-25 | Merck & Co Inc | Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals |
-
1992
- 1992-09-24 AT AT92202940T patent/ATE180671T1/de active
- 1992-09-24 EP EP92202940A patent/EP0535734B1/de not_active Expired - Lifetime
- 1992-09-24 DK DK92202940T patent/DK0535734T3/da active
- 1992-09-24 ES ES92202940T patent/ES2131515T3/es not_active Expired - Lifetime
- 1992-09-24 DE DE69229318T patent/DE69229318T2/de not_active Expired - Lifetime
- 1992-09-28 CA CA002079255A patent/CA2079255A1/en not_active Abandoned
- 1992-09-28 JP JP4258050A patent/JPH0672108B2/ja not_active Expired - Lifetime
- 1992-09-29 ZA ZA927457A patent/ZA927457B/en unknown
- 1992-09-29 AU AU26037/92A patent/AU2603792A/en not_active Abandoned
-
1999
- 1999-06-03 GR GR990401373T patent/GR3030403T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0535734B1 (de) | 1999-06-02 |
| AU2603792A (en) | 1993-04-01 |
| ES2131515T3 (es) | 1999-08-01 |
| GR3030403T3 (en) | 1999-09-30 |
| JPH05246893A (ja) | 1993-09-24 |
| DK0535734T3 (da) | 1999-08-09 |
| EP0535734A1 (de) | 1993-04-07 |
| JPH0672108B2 (ja) | 1994-09-14 |
| DE69229318T2 (de) | 1999-11-18 |
| CA2079255A1 (en) | 1993-03-31 |
| ATE180671T1 (de) | 1999-06-15 |
| DE69229318D1 (de) | 1999-07-08 |
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