WO2008057967A2 - High-potency sweetener composition with preservative and compositions sweetened therewith - Google Patents

High-potency sweetener composition with preservative and compositions sweetened therewith Download PDF

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Publication number
WO2008057967A2
WO2008057967A2 PCT/US2007/083378 US2007083378W WO2008057967A2 WO 2008057967 A2 WO2008057967 A2 WO 2008057967A2 US 2007083378 W US2007083378 W US 2007083378W WO 2008057967 A2 WO2008057967 A2 WO 2008057967A2
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WIPO (PCT)
Prior art keywords
composition
sweet taste
taste improving
sweetener
rebaudioside
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Ceased
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PCT/US2007/083378
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English (en)
French (fr)
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WO2008057967A3 (en
Inventor
Indra Prakash
Grant E. Dubois
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Coca Cola Co
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Coca Cola Co
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Publication date
Application filed by Coca Cola Co filed Critical Coca Cola Co
Priority to AU2007317371A priority Critical patent/AU2007317371B9/en
Priority to CN2007800403231A priority patent/CN101562992B/zh
Priority to EP07854560.5A priority patent/EP2094112B1/en
Priority to JP2009535473A priority patent/JP2010508824A/ja
Priority to ES07854560.5T priority patent/ES2456956T3/es
Publication of WO2008057967A2 publication Critical patent/WO2008057967A2/en
Publication of WO2008057967A3 publication Critical patent/WO2008057967A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/84—Flavour masking or reducing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/34—Sugar alcohols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides

Definitions

  • 60/739,302 entitled “Natural High-Potency Sweetener Compositions With Improved Temporal Profile And/Or Flavor Profile, Methods For Their Formulations, and Uses,” filed on November 23, 2005
  • U.S. Provisional Application No. 60/739,124 entitled “Synthetic Sweetener Compositions With Improved Temporal Profile And/Or Flavor Profile, Methods For Their Formulations, and Uses,” filed on November 23, 2005
  • U.S. Provisional Application No. 60/805,209 entitled “Natural High-Potency Tabletop Sweetener Compositions with Improved Temporal and/or Flavor Profiles, Methods for Their Formulation, and Uses,” filed on June 19, 2006
  • U.S. Provisional Application No. 60/805,216 entitled “Rebaudioside A Composition and Method for Purifying Rebaudioside A,” filed on June 19, 2006.
  • the present invention relates generally to a preservative composition comprising a high-potency sweetener composition with improved temporal profile and/or flavor profile.
  • sucrose Natural caloric sugars, such as sucrose, fructose, and glucose are utilized heavily in beverage, food, pharmaceutical, and oral hygienic/cosmetic industries due to their pleasant taste.
  • sucrose imparts a desirable taste for consumers.
  • sucrose provides superior sweetness characteristics, it is caloric. While calories are necessary for proper bodily functions, there is a need in the market to provide alternative non-caloric or Jow-caloric sweeteners with sugar-like taste for consumers with sedentary lifestyles or those who are calorie conscious.
  • non-caloric or low caloric sweeteners have associated undesirable tastes to consumers such as delayed sweetness onset; lingering sweet aftertaste; bitter taste; metallic taste; astringent taste; cooling taste; licorice-like taste; and/or the like.
  • the sweet tastes of natural and/or synthetic high-potency sweeteners are slower in onset and longer in duration than the sweet taste produced by sugar and thus change the taste balance of a food composition. Because of these differences, use of a natural high-potency sweetener to replace a bulk sweetener, such as sugar, in a food or beverage, causes an unbalanced temporal profile and/or flavor profile. In addition to the difference in temporal profile, high-potency sweeteners generally exhibit (i) lower maximal response than sugar, (ii) off tastes including bitter, metallic, cooling, astringent, licorice-like taste, etc., and/or (iii) sweetness which diminishes on iterative tasting.
  • this invention addresses the above described need by providing a sweetener composition having improved temporal profile and/or flavor profile and a method for improving the temporal profile and/or flavor profile for sweetener compositions.
  • this invention improves the temporal profile and/or flavor profile by imparting a more sugar-like temporal profile and/or flavor profile.
  • this invention comprises a sweetener composition comprising at least one preservative; at least one high- potency sweetener; and at least one sweet taste improving composition.
  • Fig. 1 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 1 on a plot of the scattering intensity versus the scattering angle 2 ⁇ in accordance with an embodiment of this invention.
  • Fig. 2 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 2 on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention.
  • Fig. 3 is a powder x-ray diffraction scan of rebaudioside A polymorph Form
  • Fig. 4 is a powder x-ray diffraction scan of rebaudioside A polymorph Form
  • Fig. 5 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 4 on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention.
  • embodiments of the present invention provide sweetener compositions comprising at least one preservative, at least one natural and/or synthetic high- potency sweetener, and at least one sweet taste improving composition.
  • embodiments of the present invention also provide edible sweetened compositions comprising at least one edible material, at least one preservative, at least one high-potency sweetener, and at least one sweet taste improving composition.
  • Preservatives in accordance with the teachings of this invention, comprise chemicals that are added to foods or beverages in order to protect against spoilage, decay, discoloration, or food-borne illness. Chemical preservatives help to maintain a food's freshness, increase shelf life, and improve or retain the nutritional value of food. They also may enhance the flavor, texture, or color of food.
  • Preservatives generally may be categorized, based on their mode of action, as antimicrobials, antioxidants, or antienzymatics, although some preservatives may fall into multiple categories.
  • Antimicrobials prevent the growth of bacteria, molds, fungi, and yeasts.
  • Antioxidants suppress fat and lipid oxidation, which causes foods to become rancid or to discolor.
  • Antioxidants also may reduce damage to nutrients and functional ingredients such as amino acids, proteins, and vitamins.
  • Antienzymatics block the natural ripening and enzymatic processes that occur in fruits and vegetables after harvest.
  • Preservatives may be used alone or in combination with other methods of food preservation including, but not limited to, drying, smoking, freezing, vacuum packing, canning, bottling, irradiation, and thermal processing.
  • the at least one preservative comprises antimicrobials, antioxidants, antienzymatics, or a combination thereof.
  • antimicrobials include sulfites, propionates, benzoates, sorbates, nitrates, nitrites, bacteriocins, salts, sugars, acetic acid, dimethyl dicarbonate (DMDC), ethanol, and ozone.
  • the at least one preservative comprises a sulfite.
  • Sulfites include, but are not limited to, sulfur dioxide, sodium bisulfite, and potassium hydrogen sulfite. They are the most commonly used food preservative, and also operate as antioxidants and antienzymatics. Sulfites are commonly used in wine, wine vinegar, beer, beverages containing sweeteners, baked items, processed cheese, dairy products, fish, fruits and vegetables, salads, pickled items, and tofu.
  • the at least one preservative comprises a propionate.
  • Propionates include, but are not limited to, propionic acid, calcium propionate, and sodium propionate. They are common in bread and other flour products.
  • the at least one preservative comprises a benzoate. Benzoates include, but are not limited to, sodium benzoate and benzoic acid. Benzoates are found naturally in cranberries and often are added to beverages, jams, pickled products, cheese, salads, meats, and margarines.
  • the at least one preservative comprises a sorbate.
  • Sorbates include, but are not limited to, potassium sorbate, sodium sorbate, calcium sorbate, and sorbic acid. Like benzoates, sorbates often are added to beverages, jams, pickled products, cheese, salads, meats, and margarines.
  • the at least one preservative comprises a nitrate and/or a nitrite. Nitrates and nitrites include, but are not limited to, sodium nitrate and sodium nitrite. They often are found in cured and packaged meats.
  • the at least one preservative comprises a bacteriocin.
  • Bacteriocins are proteinaceous toxins produced by bacteria to inhibit the growth of similar bacterial strains.
  • a commonly-used bacteriocin preservative is nisin.
  • Nisin is an inhibitory polycyclic peptide with 34 amino acid residues that is produced by fermentation using the bacterium Lactococcus lactis. It often is used in processed cheese production to extend shelf-life by suppressing spoilage and pathogenic bacteria, although it also has applications in other food and beverage production.
  • the at least one preservative comprises a salt, a sugar, and/or an acetic acid.
  • Salts inhibit the growth of microorganisms, which cause spoilage, by drawing water out of microbial cells through osmosis.
  • suitable salts include sodium chloride and potassium chloride.
  • Salt for curing often contains nitrates or nitrites, which inhibit microbial growth and help to preserve the color of the cured meat.
  • Sugar generally is fermented by lactobacilli and reduces the ability of spoilage bacteria to cultivate in food.
  • suitable sugars include dextrose, sucrose, glucose, and fructose.
  • the at least one preservative comprises acetic acid.
  • Acetic acid is used to preserve food through the process of pickling.
  • Pickling is a the process of preserving a food by soaking and storing it in a brine containing salt and/or acid, such as acetic acid. Pickling often results in anaerobic fermentation by either yeast or lactic acid bacteria.
  • the at least one preservative comprises ethanol.
  • Ethanol also known as ethyl alcohol, is produced by the metabolism of carbohydrates by yeast in the absence of oxygen and is most often found in fermented beverages. It is toxic to many microbes.
  • the at least one preservative comprises ozone.
  • Ozone is a naturally occurring gas with strong oxidizing properties. It is readily soluble in water and destroys bacteria by rupturing their cellular membranes. Ozone generally is used as an antimicrobial treatment for bottled water.
  • the at least one preservative comprises an antioxidant.
  • antioxidants include butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tert-butyl hydroquinone, propyl gallate, ascorbic acid (vitamin C), and tocopherol (vitamin E).
  • BHT butylated hydroxytoluene
  • BHA butylated hydroxyanisole
  • vitamin C ascorbic acid
  • vitamin E tocopherol
  • Antioxidants suppress the oxidation of fats and lipids in the presence of oxygen, which causes foods to become rancid or to discolor. Unsaturated fatty acids in oils and lipids are particularly susceptible to auto- oxidation in the presence of oxygen, and therefore benefit from the addition of antioxidants. Antioxidants also may reduce damage to nutrients and functional ingredients such as amino acids, proteins, and vitamins.
  • Antioxidant preservatives function by controlling free radicals in the body. Free radicals are highly reactive atoms or molecules having an unpaired electron that can damage cells and tissues in the body. A buildup of free radicals may contribute to diseases such as Parkinson's disease, Alzheimer's, and some forms of cancer. By neutralizing free radicals within the body, antioxidants can lower the incidence of such diseases. The addition of antioxidant preservatives to food therefore serves multiple purposes and may provide health benefits to the consumer.
  • Non-limiting examples of antienzymatics suitable for use as preservatives in particular embodiments of the invention include ascorbic acid, citric acid, and metal chelating agents such as ethylenediaminetetraacetic acid (EDTA). These preservatives prevent enzymes from causing fruits and vegetables to over-ripen after harvest by lowering the pH of the food to a level where the enzymes cannot operate to cause the over-ripening. Mctal- chelating agents such as EDTA operate by removing the metal cofactors that many enzymes need to operate. Chelators also may inhibit the growth of microbes.
  • a sweetener composition comprises at least one preservative, at least one natural and/or synthetic high-potency sweetener, and at least one sweet taste improving composition.
  • the amount of preservative present in the sweetener composition varies widely depending on the particular type of preservative. Those of ordinary skill in the art can discern a suitable amount of preservative. A broad range of preservative concentrations falls within the scope of this invention.
  • the at least one preservative is present in the sweetener composition in an amount in the range of about 50 to about 1,000 ppm of the edible sweetened composition.
  • embodiments of the present invention also provide edible sweetened compositions comprising at least one edible material, at least one preservative, at least one high-potency sweetener, and at least one sweet taste improving composition.
  • Edible materials in accordance with the teachings of this invention, comprise any substance that is fit or able to be consumed by humans. Most often edible materials are food or beverage substances that provide nutrition, energy, and/or functional benefits.
  • the at least one edible material comprises a beverage, a fruit, a vegetable, a meat product, a meat by-product, a dairy product, a bread product, a confection, or a combination thereof.
  • the edible sweetened composition may comprise a sweetened dried fruit product comprising dried fruit, at least one preservative, at least one high-potency sweetener, and at least one sweet taste improving composition.
  • the edible sweetened composition may comprise sweetened cured meat comprising meat, at least one preservative, at least one high-potency sweetener, and at least one sweet taste improving composition.
  • the edible sweetened composition may comprise a sweetened beverage comprising a cola, at least one preservative, at least one high-potency sweetener, and at least one sweet taste improving composition.
  • Edible materials may be, but are not limited to, solids or liquids. A broad range of preservative concentrations falls within the scope of this invention.
  • the at least one preservative is present in the edible sweetened composition in an amount in the range of about 50 to about 1,000 ppm of the edible sweetened composition.
  • the sweetener compositions comprise at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition.
  • the combination of the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition comprises the "sweetener composition.”
  • preservative is synonymous with a “sweetcnable composition.”
  • the combination of the sweetener composition and at least one preservative comprises a "sweetened composition.”
  • the sweetener composition comprises at least one natural and/or synthetic high-potency sweetener.
  • natural high-potency sweetener NHPS
  • NHPS composition NHPS composition
  • natural high-potency sweetener composition any sweetener found in nature which may be in raw, extracted, purified, or any other form, singularly or in combination thereof and characteristically have a sweetness potency greater than sucrose, fructose, or glucose, yet have less calories.
  • Non-limiting examples of NHPSs suitable for embodiments of this invention include rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, dulcoside A, dulcoside B, rubusoside, stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, siamenoside, monatin and its salts (monatin SS, RR, RS, SR), curculin, glycyrrhizic acid and its salts, thaumatin, monellin, mabinlin, brazzein, hemandulcin, phyllodulcin, glycyphyllin, phloridzin, trilobatin, baiyunoside, osladin, polypodoside A, pterocaryoside A, pterocaryoside B, mukurozioside,
  • NHPS also includes modified NHPSs.
  • Modified NHPSs include NHPSs which have been altered naturally.
  • a modified NHPS includes, but is not limited to, NHPSs which have been fermented, contacted with enzyme, or derivatized or substituted on the NHPS.
  • at least one modified NHPS may be used in combination with at least one NHPS.
  • at least one modified NHPS may be used without a NHPS.
  • modified NHPSs may be substituted for a NHPS or may be used in combination with NHPSs for any of the embodiments described herein.
  • modified NHPS is not expressly described as an alternative to an unmodified NHPS, but it should be understood that modified NHPSs can be substituted for NHPSs in any embodiment disclosed herein.
  • extracts of a NHPS may be used in any purity percentage.
  • the purity of the NHPS may range for example from about 25% to about 100%. According to other embodiments, the purity of the NHPS may range from about 50% to about 100% from about 70% to about 100%; from about 80% to about 100%; from about 90% to about 100%; from about 95% to about 100%; from about 95% to about 99.5%; from about 96% to about 100%; from about 97% to about 100%; from about 98% to about 100%; and from about 99% to about 100%.
  • Purity represents the weight percentage of a respective NHPS compound present in a NHPS extract, in raw or purified form.
  • a steviolglycoside extract comprises a particular steviolglycoside in a particular purity, with the remainder of the stevioglycoside extract comprising a mixture of other steviolglycosides.
  • substantially pure rebaudioside A is crystallized in a single step from an aqueous organic solution comprising at least one organic solvent and water in an amount from about 10 % to about 25 % by weight, more particularly from about 15 % to about 20 % by weight.
  • Organic solvents desirably comprise alcohols, acetone, and acetonitile.
  • Alcohols include ethanol, methanol, isopranol, 1 - propanol, 1-butanol, 2-butanol, tert-butanol, and isobutanol.
  • the at least one organic solvent comprises a mixture of ethanol and methanol present in the aqueous organic solution in a weight ratio ranging from about 20 parts to about 1 part ethanol to 1 part methanol, more desirably from about 3 parts to about 1 part ethanol to 1 part methanol.
  • the weight ratio of the aqueous organic solvent and crude rebaudioside A ranges from about 10 to about 4 parts aqueous organic solvent to 1 part crude rebaudioside A, more particularly from about 5 to about 3 parts aqueous organic solvent to 1 part crude rebaudioside A.
  • the method of purifying rebaudioside A is carried out at approximately room temperature.
  • the method of purifying rebaudioside A further comprises the step of heating the rebaudioside A solution to a temperature in a range from about 20°C to about 40°C, or in another embodiment to a reflux temperature, for about 0.25 hours to about 8 hours.
  • the method for purifying rebaudioside A comprises the step of heating the rebaudioside A solution
  • the method further comprises the step of cooling the rebaudioside A solution to a temperature in the range from about 4°C to about 25 °C for about 0.5 hours to about 24 hours.
  • the purity of rebaudioside A may range from about 50% to about 100%; from about 70% to about 100%; from about 80% to about 100%; from about 90% to about 100%; from about 95% to about 100%; from about 95% to about 99.5%; about 96% to about 100%; from about 97% to about 100%; from about 98% to about 100%; and from about 99% to about 100%.
  • the substantially pure rebaudioside A composition upon crystallization of crude rebaudioside A, the substantially pure rebaudioside A composition comprises rebaudioside A in a purity greater than about 95 % by weight up to about 100% by weight on a dry basis.
  • substantially pure rebaudioside A comprises purity levels of rebaudioside A greater than about 97 % up to about 100% rebaudioside A by weight on a dry basis, greater than about 98 % up to about 100% by weight on a dry basis, or greater than about 99 % up to about 100% by weight on a dry basis.
  • the rebaudioside A solution during the single crystallization step may be stirred or unstirred.
  • the method of purifying rebaudioside A further comprises the step of seeding (optional step) the rebaudioside A solution at an appropriate temperature with high-purity crystals of rebaudioside A sufficient to promote crystallization of the rebaudioside A to form pure rebaudioside A.
  • An amount of rebaudioside A sufficient to promote crystallization of substantially pure rebaudioside A comprises an amount of rebaudioside A from about 0.0001 % to about 1 % by weight of the rebaudioside A present in the solution, more particularly from about 0.01 % to about 1 % by weight.
  • An appropriate temperature for the step of seeding comprises a temperature in a range from about ] 8°C to about 35"C.
  • the method of purifying rebaudioside A further comprises the steps of separating and washing the substantially pure rebaudioside A composition.
  • the substantially pure rebaudioside A composition may be separated from the aqueous organic solution by a variety of solid-liquid separation techniques that utilize centrifugal force, that include, without limitation, vertical and horizontal perforated basket centrifuge, solid bowl centrifuge, decanter centrifuge, peeler type centrifuge, pusher type centrifuge, Heinkel type centrifuge, disc stack centrifuge and cyclone separation.
  • separation may be enhanced by any of pressure, vacuum, and gravity filtration methods, that include, without limitation, the use of belt, drum, nutsche type, leaf, plate, Rosenmund type, sparkler type, and bag filters and filter press.
  • Operation of the rebaudioside A solid-liquid separation device may be continuous, semi-continuous or in batch mode.
  • the substantially pure rebaudioside A composition also may be washed on the separation device using various aqueous organic solvents and mixtures thereof.
  • the substantially pure rebaudioside A composition can be dried partially or totally on the separation device using any number of gases, including, without limitation, nitrogen and argon, to evaporate residual liquid solvent.
  • the substantially pure rebaudioside A composition may be removed automatically or manually from the separation device using liquids, gases or mechanical means by either dissolving the solid or maintaining the solid form.
  • A further comprises the step of drying the substantially pure rebaudioside A composition using techniques well known to those skilled in the art, non-limiting examples of which include the use of a rotary vacuum dryer, fluid bed dryer, rotary tunnel dryer, plate dryer, tray dryer, Nauta type dryer, spray dryer, flash dryer, micron dryer, pan dryer, high and low speed paddle dryer and microwave dryer.
  • the step of drying comprises drying the substantially pure rebaudioside A composition using a nitrogen or argon purge to remove the residual solvent at a temperature in a range from about 40°C to about 60°C for about 5 hours to about 100 hours.
  • the method of purifying rebaudioside A further comprises the step of slurrying the composition of substantially pure rebaudioside A with an aqueous organic solvent prior to the step of drying the substantially pure rebaudioside A composition.
  • the slurry is a mixture comprising a solid and an aqueous organic or organic solvent, wherein the solid comprises the substantially pure rebaudioside A composition and is only sparingly soluble in the aqueous organic or organic solvent.
  • the substantially pure rebaudioside A composition and aqueous organic solvent are present in the slurry in a weight ratio ranging from about 15 parts to 1 part aqueous organic solvent to 1 part substantially pure rebaudioside A composition.
  • the slurry is maintained at room temperature.
  • the step of slurrying comprises heating the slurry to a temperature in a range from about 20°C to about 40°C.
  • the substantially pure rebaudioside A composition is slurried for about 0.5 hours to about 24 hours.
  • the method of purifying rebaudioside A further comprises the steps of separating the substantially pure rebaudioside A composition from the aqueous organic or organic solvent of the slurry and washing the substantially pure rebaudioside A composition followed by the step of drying the substantially pure rebaudioside A composition.
  • the method of purifying rebaudioside A described herein may be repeated or the substantially pure rebaudioside A composition may be purified further using an alternative purification method, such as the column chromatography.
  • the purification of rebaudioside A by crystallization as described above results in the formation of at least three different polymorphs: Form 1 : a rebaudioside A hydrate; Form 2: an anhydrous rebaudioside A; and Form 3: a rebaudioside A solvate.
  • the purification of rebaudioside A may result in the formation of an amorphous form of rebaudioside A, Form 4.
  • the aqueous organic solution and temperature of the purification process influence the resulting polymorph and amorphous forms in the substantially pure rebaudioside A composition.
  • Figures 1-5 are exemplary powder x-ray diffraction (XRPD) scans of the polymorph and amorphous forms of rebaudioside A: Form 1 (hydrate), Form 2 (anhydrate), Form 3A (methanol solvate), Form 3B (ethanol solvate), and Form 4 (amorphous), respectively.
  • XRPD powder x-ray diffraction
  • the type of polymorph formed is dependent on the composition of the aqueous organic solution, the temperature of the crystallization step, and the temperature during the drying step.
  • Form 1 and Form 3 are formed during the single crystallization step while Form 2 is formed during the drying step after conversion from Form 1 or Form 3.
  • Low temperatures during the crystallization step in the range of about 20°C to about 50°C, and a low ratio of water to the organic solvent in the aqueous organic solvent results in the formation of Form 3.
  • High temperatures during the crystallization step in the range of about 50°C to about 8O 0 C, and a high ratio of water to the organic solvent in the aqueous organic solvent results in the formation of the Form 1.
  • Form 1 can be converted to Form 3 by slurrying in an anhydrous solvent at room temperature (2 -16 hours) or at reflux for approximately (0.5-3 hours).
  • Form 3 can be converted to Form 1 by slurrying the polymorph in water at room temperature for approximately 16 hours or at reflux for approximately 2-3 hours.
  • Form 3 can be converted to the Fo ⁇ n 2 during the drying process; however, increasing either the drying temperature above 70°C or the drying time of a substantially pure rebaudioside A composition can result in decomposition of the rebaudioside A and increase the remaining rebaudioside B impurity in the substantially pure rebaudioside A composition.
  • Form 2 can be converted to Form 1 with the addition of water.
  • Form 4 may be formed from Form 1 , 2, 3, or combinations thereof, using methods well known to those of ordinary skill in the art. Non-limiting examples of such methods include melt-processing, ball milling, crystallization, lyophilization, cryo-grinding, and spray-drying.
  • Form 4 can be prepared from a substantially pure rebaudioside A composition obtained by the purification methods described hereinabove by spray-drying a solution of the substantially pure rebaudioside A composition
  • synthetic sweetener refers to any compositions which are not found in nature and characteristically have a sweetness potency greater than sucrose, fructose, or glucose, yet have less calories.
  • synthetic sweeteners suitable for embodiments of this invention include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotame, N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L- ⁇ -asparty l]-L-pheny lalanine 1 - methyl ester, N-[N-[3-(3-hydroxy-4-methoxyphenyl)-3-methylbutyl]-L- ⁇ -aspartyl]-L- phenylalanine 1-methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl
  • the NHPS and synthetic sweeteners may be used individually or in combination with other NHPS and/or synthetic sweeteners.
  • the sweetener composition may comprise a single NHPS or a single synthetic sweetener; a single NHPS in combination with a single synthetic sweetener; one or more NHPSs in combination with a single synthetic sweetener; a single NHPS in combination with one or more synthetic sweeteners; or one or more NHPSs in combination with one or more synthetic sweeteners.
  • a plurality of natural and/or synthetic high-potency sweeteners may be used as long as the combined effect does not adversely affect the taste of the sweetener composition.
  • particular embodiments comprise combinations of NHPSs, such as steviolglycosides.
  • suitable stevioglycosides which may be combined include rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, dulcoside A, dulcoside B, rubusoside, stevioside, or steviolbioside.
  • the combination of high-potency sweeteners comprises rebaudioside A in combination with rebaudioside B, rebaudioside C, rebaudioside E, rebaudioside F, stevioside, steviolbioside, dulcoside A, or combinations thereof.
  • rebaudioside A is present in the combination of high-potency sweeteners in an amount in the range of about 50 to about
  • rebaudioside B is present in the combination of high-potency sweeteners in an amount in the range of about 1 to about 8 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 2 to about 5 weight percent, and still more desirably in the range of about 2 to about 3 weight percent.
  • rebaudioside C is present in the combination of high-potency sweeteners in an amount in the range of about 1 to about 10 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 3 to about 8 weight percent, and still more desirably in the range of about 4 to about 6 weight percent.
  • rebaudioside E is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about
  • rebaudioside F is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about
  • dulcoside A is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about
  • dulcoside B is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent.
  • stevioside is present in the combination of high-potency sweeteners in an amount in the range of about 0.5 to about 10 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 1 to about 6 weight percent, and still more desirably in the range of about 1 to about 4 weight percent.
  • steviolbioside is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent.
  • the high-potency sweetener composition comprises a combination of rebaudioside A, stevioside, rebaudioside B, rebaudioside C, and rebaudioside F; wherein rebaudioside A is present in the combination of high-potency sweeteners in an amount in the range of about 75 to about 85 weight percent based on the total weight of the combination of high-potency sweeteners, stevioside is present in an amount in the range of about 1 to about 6 weight percent, rebaudioside B is present in an amount in the range of about 2 to about 5 weight percent, rebaudioside C is present in an amount in the range of about 3 to about 8 weight percent, and rebaudioside F is present in an amount in the range of about 0.1 to about 2 weight percent.
  • rebaudioside A is present in the combination of high-potency sweeteners in an amount in the range of about 75 to about 85 weight percent based on the total weight of the combination of high-potency sweeteners
  • stevioside
  • the sweetener composition can be customized to obtain a desired calorie content.
  • a low-caloric or non-caloric NHPS may be combined with a caloric natural sweetener and/or other caloric additives to produce a sweetener composition with a preferred calorie content.
  • the sweetener composition also comprises a sweet taste improving composition, non-limiting examples of which include carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, nucleotides, organic acids, inorganic acids, organic salts including organic acid salts and organic base salts, inorganic salts, bitter compounds, flavorants and flavoring ingredients, astringent compounds, proteins or protein hydrolysates, surfactants, emulsifiers, flavonoids, alcohols, polymers, other sweet taste improving taste additives imparting such sugar-like characteristics, and combinations thereof.
  • a sweet taste improving composition include carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, nucleotides, organic acids, inorganic acids, organic salts including organic acid salts and organic base salts, inorganic salts, bitter compounds, flavorants and flavoring ingredients, astringent compounds, proteins or
  • a single sweet taste improving composition may be used in combination with a single natural and/or synthetic high-potency sweetener.
  • a single sweet taste improving composition may be used in combination with one or more natural and/or synthetic high-potency sweeteners.
  • one or more sweet taste improving compositions may be used in combination with a single natural and/or synthetic high-potency sweetener.
  • there may be a plurality of sweet taste improving combinations used in combination with one or more natural and/or synthetic high-potency sweeteners.
  • combinations of at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition suppress, reduce, or eliminate undesirable taste and impart sugar-like characteristics to the sweetener composition.
  • the phrase "undesirable taste” includes any taste property which is not imparted by sugars, e.g. glucose, sucrose, fructose, or similar saccharides.
  • Non-limiting examples of undesirable tastes include delayed sweetness onset, lingering sweet aftertaste, metallic taste, bitter taste, cooling sensation taste or menthol-like taste, licorice-like taste, and/or the like.
  • a sweetener composition exhibits a more sugar-like temporal and/or sugar-like flavor profile than a sweetener composition comprising at least one natural and/or synthetic high-potency sweetener, but without a sweet taste improving composition is provided.
  • sweetener composition comprising at least one natural and/or synthetic high-potency sweetener, but without a sweet taste improving composition.
  • sucrose-like characteristic “sugar-like taste,” “sugar-like sweet,” “sugary,” and “sugar-like” are synonymous.
  • Sugar-like characteristics include any characteristic similar to that of sucrose and include, but are not limited to, maximal response, flavor profile, temporal profile, adaptation behavior, mouthfeel, concentration/response function behavior, tastant and flavor/sweet taste interactions, spatial pattern selectivity, and temperature effects.
  • a characteristic is more sugar-like is determined by expert sensory panel assessments of sugar and compositions comprising at least one natural and/or synthetic high- potency sweetener, both with and without a sweet taste improving composition. Such assessments quantify similarities of the characteristics of compositions comprising at least one natural and/or synthetic high-potency sweetener, both with and without a sweet taste improving composition, with those comprising sugar. Suitable procedures for determining whether a composition has a more sugar-like taste are well known in the art. [0069] In a particular embodiment, a panel of assessors is used to measure the reduction of sweetness linger.
  • a panel of assessors (generally 8 to 12 individuals) is trained to evaluate sweetness perception and measure sweetness at several time points from when the sample is initially taken into the mouth until 3 minutes after it has been expectorated. Using statistical analysis, the results are compared between samples containing additives and samples that do not contain additives. A decrease in score for a time point measured after the sample has cleared the mouth indicates there has been a reduction in sweetness perception.
  • the panel of assessors may be trained using procedures well known to those of ordinary skill in the art.
  • the panel of assessors may be trained using the SpectrumTM Descriptive Analysis Method (Meilgaard et al, Sensory Evaluation Techniques. 3 rd edition, Chapter 11).
  • the focus of training should be the recognition of and the measure of the basic tastes; specifically, sweet.
  • each assessor should repeat the measure of the reduction of sweetness linger about three to about five times per sample, taking at least a five minute break between each repetition and/or sample and rinsing well with water to clear the mouth.
  • the method of measuring sweetness comprises taking a 1OmL sample into the mouth, holding the sample in the mouth for 5 seconds and gently swirling the sample in the mouth, rating the sweetness intensity perceived at 5 seconds, expectorating the sample (without swallowing following expectorating the sample), rinsing with one mouthful of water (e.g., vigorously moving water in mouth as if with mouth wash) and expectorating the rinse water, rating the sweetness intensity perceived immediately upon expectorating the rinse water, waiting 45 seconds and, while wating those 45 seconds, identifying the time of maximum perceived sweetness intensity and rating the sweetness intensity at that time (moving the mouth normally and swallowing as needed), rating the sweetness intensity after another 10 seconds, rating the sweetness intensity after another 60 seconds (cumulative 120 seconds after rinse), and rating the sweetness intensity after still another 60 seconds (cumulative 180 seconds after rinse). Between samples take a 5 minute break, rinsing well with water to clear the mouth.
  • one mouthful of water e.g., vigorously moving water in mouth as if with mouth wash
  • sweet taste improving compositions include carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, nucleotides, organic acids, inorganic acids, organic salts including organic acid salts and organic base salts, inorganic salts, bitter compounds, flavorants and flavoring ingredients, astringent compounds, proteins or protein hydrolysates, surfactants, emulsifiers, flavonoids, alcohols, polymers, other sweet taste improving taste additives imparting such sugar-like characteristics, and combinations thereof.
  • carbohydrate generally refers to aldehyde or ketone compounds substituted with multiple hydroxyl groups, of the general formula (CH2 ⁇ ) n , wherein n is 3-30, as well as their oligomers and polymers.
  • the carbohydrates of the present invention can, in addition, be substituted or deoxygenated at one or more positions.
  • Carbohydrates, as used herein, encompass unmodified carbohydrates, carbohydrate derivatives, substituted carbohydrates, and modified carbohydrates.
  • the phrases “carbohydrate derivatives", “substituted carbohydrate”, and “modified carbohydrates” are synonymous.
  • Modified carbohydrate means any carbohydrate wherein at least one atom has been added, removed, substituted, or combinations thereof.
  • carbohydrate derivatives or substituted carbohydrates include substituted and unsubstituted monosaccharides, disaccharides, oligosaccharides, and polysaccharides.
  • the carbohydrate derivatives or substituted carbohydrates optionally can be deoxygenated at any corresponding C-position, and/or substituted with one or more moieties such as hydrogen, halogen, haloalkyl, carboxyl, acyl, acyloxy, amino, amido, carboxyl derivatives, alkylamino, dialkylamino, arylamino, alkoxy, aryloxy, nitro, cyano, sulfo, mercapto, imino, sulfonyl, sulfenyl, sulfinyl, sulfamoyl, carboalkoxy, carboxamido, phosphonyl, phosphinyl, phosphoryl, phosphino, thioester, thioether, oximino, hydrazino, carbamyl, phospho, phosphonato, or any other viable functional group provided the carbohydrate derivative or substituted carbohydrate functions to improve the sweet taste
  • Non-limiting examples of carbohydrates in embodiments of this invention include tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., o-cyclodextrin, ⁇ - cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palati ⁇ ose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cell
  • the carbohydrates as used herein may be in either the D- or L- configuration.
  • polyol refers to a molecule that contains more than one hydroxyl group.
  • a polyol may be a diol, triol, or a tetraol which contain 2, 3, and 4 hydroxyl groups, respectively.
  • a polyol also may contain more than four hydroxyl groups, such as a pentaol, hexaol, heptaol, or the like, which contain, 5, 6, or 7 hydroxyl groups, respectively.
  • a polyol also may be a sugar alcohol, polyhydric alcohol, or polyalcohol which is a reduced form of carbohydrate, wherein the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group.
  • Non-limiting examples of sweet taste improving polyol additives in embodiments of this invention include erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio- oligosaccharides, reduced maltose syrup, reduced glucose syrup, and sugar alcohols or any other carbohydrates capable of being reduced which do not adversely affect the taste of the sweetener composition.
  • Suitable sweet taste improving amino acid additives for use in embodiments of this invention include, but are not limited to, aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, carnitine, aminobutyric acid (alpha-, beta-, or gamma- isomers), glutamine, hydroxy proline, taurine, norvaline, sarcosine, and their salt forms such as sodium or potassium salts or acid salts.
  • the sweet taste improving amino acid additives also may be in the D- or L- configuration and in the mono-, di-, or tri- form of the same or different amino acids. Additionally, the amino acids may be ⁇ -, ⁇ -, ⁇ -, ⁇ -, and ⁇ - isomers if appropriate. Combinations of the foregoing amino acids and their corresponding salts (e.g., sodium, potassium, calcium, magnesium salts or other alkali or alkaline earth metal salts thereof, or acid salts) also are suitable sweet taste improving additives in embodiments of this invention.
  • the amino acids may be natural or synthetic.
  • the amino acids also may be modified.
  • Modified amino acids refers to any amino acid wherein at least one atom has been added, removed, substituted, or combinations thereof (e.g., N-alkyl amino acid, N-acyl amino acid, or N-methyl amino acid).
  • modified amino acids include amino acid derivatives such as trimethyl glycine, N-methyl-glycine, and N-methyl-alanine.
  • amino acids encompass both modified and unmodified amino acids.
  • modified amino acid also may encompass peptides and polypeptides (e.g., dipeptides, tripeptides, tetrapeptides, and pentapeptides) such as glutathione and L-alanyl-L-glutamine.
  • Suitable sweet taste improving polyamino acid additives include poly-L- aspartic acid, poly-L-lysine (e.g., poly-L- ⁇ - lysine or poly-L- ⁇ -lysine), poly-L-ornithine (e.g., poly-L- ⁇ -ornithine or poly-L- ⁇ -omithine), poly-L-arginine, other polymeric fo ⁇ ns of amino acids, and salt forms thereof (e.g., magnesium, calcium, potassium, or sodium salts such as L- glutamic acid mono sodium salt).
  • the sweet taste improving polyamino acid additives also may be in the D- or L- configuration.
  • polyamino acids may be ⁇ -, ⁇ -, ⁇ -, ⁇ -, and ⁇ - isomers if appropriate.
  • Combinations of the foregoing polyamino acids and their corresponding salts e.g., sodium, potassium, calcium, magnesium salts or other alkali or alkaline earth metal salts thereof or acid salts
  • the polyamino acids described herein also may comprise co-polymers of different amino acids.
  • the polyamino acids may be natural or synthetic.
  • polyamino acids also may be modified, such that at least one atom has been added, removed, substituted, or combinations thereof (e.g., N-alkyl polyamino acid or N-acyl polyamino acid).
  • polyamino acids encompass both modified and unmodified polyamino acids.
  • modified polyamino acids include, but are not limited to polyamino acids of various molecular weights (MW), such as poly-L- ⁇ -lysine with a MW of 1,500, MW of 6,000, MW of 25,200, MW of 63,000, MW of 83,000, or MW of 300,000.
  • MW molecular weights
  • Suitable sweet taste improving sugar acid additives for use in embodiments of this invention include, but are not limited to, aldonic, uronic, aldaric, alginic, gluconic, glucuronic, glucaric, galactaric, galacturonic, and their salts (e.g., sodium, potassium, calcium, magnesium salts or other physiologically acceptable salts), and combinations thereof.
  • Suitable sweet taste improving nucleotide additives for use in embodiments of this invention include, but are not limited to, inosine monophosphate ("IMP"), guanosine monophosphate (“GMP”), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, and their alkali or alkaline earth metal salts, and combinations thereof.
  • IMP inosine monophosphate
  • GMP guanosine monophosphate
  • AMP adenosine monophosphate
  • CMP cytosine monophosphate
  • UMP uracil monophosphate
  • nucleotides described herein also may comprise nucleotide-related additives, such as nucleosides or nucleic acid bases (e.g., guanine, cytosine, adenine, thymine, uracil).
  • nucleosides or nucleic acid bases e.g., guanine, cytosine, adenine, thymine, uracil.
  • Suitable sweet taste improving organic acid additives include any compound which comprises a -COOH moiety.
  • Suitable sweet taste improving organic acid additives for use in embodiments of this invention include, but are not limited to, C2-C30 carboxylic acids, substituted hydroxyl C1-C30 carboxylic acids, benzoic acid, substituted benzoic acids (e.g.
  • 2,4-dihydroxybenzoic acid substituted cinnamic acids, hydroxyacids, substituted hydroxybenzoic acids, substituted cyclohexyl carboxylic acids, tannic acid, lactic acid, tartaric acid, citric acid, gluconic acid, glucoheptonic acids, adipic acid, hydroxycitric acid, malic acid, fruitaric acid (a blend of malic, fumaric, and tartaric acids), fumaric acid, maleic acid, succinic acid, chlorogenic acid, salicylic acid, creatine, glucosamine hydrochloride, glucono delta lactone, caffeic acid, bile acids, acetic acid, ascorbic acid, alginic acid, erythorbic acid, polyglutamic acid, and their alkali or alkaline earth metal salt derivatives thereof.
  • the sweet taste improving organic acid additives also may be in either the D- or L- configuration.
  • Suitable sweet taste improving organic acid salt additives include, but are not limited to, sodium, calcium, potassium, and magnesium salts of all organic acids, such as salts of citric acid, malic acid, tartaric acid, fumaric acid, lactic acid (e.g., sodium lactate), alginic acid (e.g., sodium alginate), ascorbic acid (e.g., sodium ascorbate), benzoic acid (e.g., sodium benzoate or potassium benzoate), and adipic acid.
  • organic acids such as salts of citric acid, malic acid, tartaric acid, fumaric acid, lactic acid (e.g., sodium lactate), alginic acid (e.g., sodium alginate), ascorbic acid (e.g., sodium ascorbate), benzoic acid (e.g., sodium benzoate or potassium benzoate), and adipic acid.
  • sweet taste improving organic acid salt additives described optionally may be substituted with one or more of the following moiety selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, halo, haloalkyl, carboxyl, acyl, acyloxy, amino, amido, carboxyl derivatives, alkylamino, dialkylamino, arylamino, alkoxy, aryloxy, nitro, cya ⁇ o, sulfo, thiol, imine, sulfonyl, sulfenyl, sulfinyl, sulfamyl, carboxalkoxy, carboxamido, phosphonyl, phosphinyl, phosphoryl, phosphino, thioester, thioether, anhydride, oximino, hydrazino, carbamyl, phospho, phosphonato, and any other viable functional group, provided the substitute
  • Suitable sweet taste improving inorganic acid additives for use in embodiments of this invention include, but are not limited to, phosphoric acid, phosphorous acid, polyphosphoric acid, hydrochloric acid, sulfuric acid, carbonic acid, sodium dihydrogen phosphate, and their corresponding alkali or alkaline earth metal salts thereof (e.g., inositol hexaphosphate Mg/Ca).
  • Suitable sweet taste improving bitter compound additives for use in embodiments of this invention include, but are not limited to, caffeine, quinine, urea, bitter orange oil, naringin, quassia, and salts thereof.
  • Suitable sweet taste improving flavorant and flavoring ingredient additives for use in embodiments of this invention include, but are not limited to, vanillin, vanilla extract, mango extract, cinnamon, citrus, coconut, ginger, viridiflorol, almond, menthol (including menthol without mint), grape skin extract, and grape seed extract.
  • "Flavorant” and “flavoring ingredient” are synonymous, and include natural or synthetic substances or combinations thereof. Flavorants also include any other substance which imparts flavor, and may include natural or non-natural (synthetic) substances which are safe for human or animals when used in a generally accepted range.
  • Non-limiting examples of proprietary flavorants include D ⁇ hlerTM Natural Flavoring Sweetness Enhancer K 14323 (D ⁇ hlerTM, Da ⁇ nstadt, Germany), SymriseTM Natural Flavor Mask for Sweeteners 161453 and 164126 (Symrisc, HolzmindenTM, Germany), Natural AdvantageTM Bitterness Blockers 1 , 2, 9 and 10 (Natural AdvantageTM, Freehold, New Jersey, U.S.A.), and SucramaskTM (Creative Research Management, Stockton, California, U.S.A.).
  • Suitable sweet taste improving polymer additives for use in embodiments of this invention include, but are not limited to, chitosan, pectin, pectic, pectinic, polyuronic, polygalacturonic acid, starch, food hydrocolloid or crude extracts thereof (e.g., gum acacia Senegal (FibergumTM), gum acacia seyal, carageenan), poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), poly-L-ornithine (e.g., poly-L- ⁇ -ornithine or poly-L- ⁇ -ornithine), polyarginine, polypropylene glycol, polyethylene glycol, polyethylene glycol methyl ether), polyaspartic acid, polyglutamic acid, polyethyleneimine, alginic acid, sodium alginate, propylene glycol alginate, sodium hexametaphosphate (SHMP
  • Suitable sweet taste improving protein or protein hydrolysate additives for use in embodiments of this invention include, but are not limited to, bovine serum albumin (BSA), whey protein (including fractions or concentrates thereof such as 90% instant whey protein isolate, 34% whey protein, 50% hydrolyzed whey protein, and 80% whey protein concentrate), soluble rice protein, soy protein, protein isolates, protein hydrolysatcs, reaction products of protein hydrolysates, glycoproteins, and/or proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, asparagine, glutamine, arginine, valine, isoleucine, leucine, norvaline, methionine, proline, tyrosine, hydroxyproline, and the like), collagen (e.g., gelatin), partially hydrolyzed collagen (e.g., hydrolyzed fish collagen), and collagen hydrolysates (e.g., B
  • Suitable sweet taste improving surfactant additives for use in embodiments of this invention include, but are not limited to, polysorbates (e.g., polyoxyethylene sorbitan monooleate (polysorbate 80), polysorbate 20, polysorbate 60), sodium dodecylbenzenesulfonate, dioctyl sulfosuccinate or dioctyl sulfosuccinate sodium, sodium dodecyl sulfate, cetylpyridinium chloride (hexadecylpyridinium chloride), hexadecyltrimethylammonium bromide, sodium cholate, carbamoyl, choline chloride, sodium glycocholate, sodium taurodeoxycholate, lauric arginate, sodium stearoyl lactylate, sodium taurocholate, lecithins, sucrose oleate esters, sucrose stearate esters, sucrose palmitate esters, sucrose laurate
  • Suitable sweet taste improving flavonoid additives for use in embodiments of this invention generally are classified as flavonols, flavones, flavanones, flavan-3-ols, isoflavones, or anthocyanidins.
  • flavonoid additives include catechins (e.g., green tea extracts such as PolyphenonTM 60, PolyphenonTM 30, and
  • PolyphenonTM 25 Mitsubishi Chemical Company, Ltd., Japan
  • polyphenols polyphenols
  • rutins e.g., enzyme modified rutin SanmelinTM AO (San-Ei Gen F.F.I., Inc., Osaka, Japan)
  • neohesperidin naringin
  • neohesperidin dihydrochalcone and the like.
  • Suitable sweet taste improving alcohol additives for use in embodiments of this invention include, but are not limited to, ethanol.
  • Suitable sweet taste improving astringent compound additives include, but are not limited to, tannic acid, europium chloride (EuCI 3 ), gadolinium chloride (GdCb), terbium chloride (TbCb), alum, tannic acid, and polyphenols (e.g., tea polyphenols).
  • Suitable sweet taste improving vitamins include nicotinamide (Vitamin B3) and pyridoxal hydrochloride (Vitamin B6).
  • the sweet taste improving compositions also may comprise natural and/or synthetic high-potency sweeteners.
  • the sweetener composition comprises at least one NHPS
  • the at least one sweet taste improving composition may comprise a synthetic high-potency sweetener, non-limiting examples of which include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotame, N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L- ⁇ - aspartyl]-L-phenylalanine 1 -methyl ester, N-[N-[3-(3-hydroxy-4-methoxyphenyl)-3- methylbutyl]-L- ⁇ -aspartyl]-L-phenylalanine 1 -methyl ester, N-[N-[3-(3-methoxy-4- hydroxyphe ⁇ yl)prop
  • the sweet taste improving compositions also may be in salt form which may be obtained using standard procedures well known in the art.
  • the term “salt” also refers to complexes that retain the desired chemical activity of the sweet taste improving compositions of the present invention and are safe for human or animal consumption in a generally acceptable range.
  • Alkali metal (for example, sodium or potassium) or alkaline earth metal (for example, calcium or magnesium) salts also can be made. Salts also may include combinations of alkali and alkaline earth metals.
  • Non-limiting examples of such salts are (a) acid addition salts formed with inorganic acids and salts formed with organic acids; (b) base addition salts formed with metal cations such as calcium, bismuth, barium, magnesium, aluminum, copper, cobalt, nickel, cadmium, sodium, potassium, and the like, or with a cation formed from ammonia, N,N-dibenzylethylenediamine, D-glucosamine, tetraethylammonium, or ethylenediamine; or (c) combinations of (a) and (b).
  • metal cations such as calcium, bismuth, barium, magnesium, aluminum, copper, cobalt, nickel, cadmium, sodium, potassium, and the like, or with a cation formed from ammonia, N,N-dibenzylethylenediamine, D-glucosamine, tetraethylammonium, or ethylenediamine
  • metal cations such as calcium, bismuth, bar
  • any salt forms which may be derived from the sweet taste improving compositions may be used with the embodiments of the present invention as long as the salts of the sweet taste improving additives do not adversely affect the taste of the sweetener compositions comprising the at least one natural and/or synthetic high-potency sweetener.
  • the salt forms of the additives can be added to the natural and/or synthetic sweetener composition in the same amounts as their acid or base forms.
  • suitable sweet taste improving inorganic salts useful as sweet taste improving additives include, but are not limited to, sodium chloride, potassium chloride, sodium sulfate, potassium citrate, europium chloride (EuCb), gadolinium chloride (GdCb), terbium chloride (TbCb), magnesium sulfate, alum, magnesium chloride, mono-, di-, tri-basic sodium or potassium salts of phosphoric acid (e.g., inorganic phosphates), salts of hydrochloric acid (e.g., inorganic chlorides), sodium carbonate, sodium bisulfate, and sodium bicarbonate.
  • EuCb europium chloride
  • GdCb gadolinium chloride
  • TbCb terbium chloride
  • magnesium sulfate alum
  • magnesium chloride mono-, di-, tri-basic sodium or potassium salts of phosphoric acid (e.g., inorganic phosphates), salts of hydrochloric
  • suitable organic salts useful as sweet taste improving additives include, but are not limited to, choline chloride, alginic acid sodium salt (sodium alginate), glucohepto ⁇ ic acid sodium salt, gluconic acid sodium salt (sodium gluconate), gluconic acid potassium salt (potassium gluconate), guanidine HCl, glucosamine HCI 1 amiloride HCI, monosodium glutamate (MSG), adenosine monophosphate salt, magnesium gluconate, potassium tartrate (monohydrate), and sodium tartrate (dihydrate).
  • choline chloride alginic acid sodium salt (sodium alginate), glucohepto ⁇ ic acid sodium salt, gluconic acid sodium salt (sodium gluconate), gluconic acid potassium salt (potassium gluconate), guanidine HCl, glucosamine HCI 1 amiloride HCI, monosodium glutamate (MSG), adeno
  • combinations of at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition improve the temporal profile and/or flavor profile, including the osmotic taste, to be more sugar-like.
  • One of ordinary skill in the art may arrive at all the possible combinations of natural and/or synthetic high-potency sweeteners and sweet taste improving compositions.
  • non-limiting combinations of the natural and/or synthetic high-potency sweetener and sweet taste improving compositions include:
  • At least one natural and/or synthetic high-potency sweetener at least one carbohydrate, at least one polyol, at least one amino acid, and at least one other sweet taste improving additive;
  • At least one natural and/or synthetic high-potency sweetener at least one carbohydrate, and at least one polyol;
  • At least one natural and/or synthetic high-potency sweetener at least one carbohydrate, and at least one amino acid;
  • At least one natural and/or synthetic high-potency sweetener at least one polyol, and at least one other sweet taste improving additive;
  • At least one natural and/or synthetic high-potency sweetener at least one amino acid, and at least one other sweet taste improving additive;
  • At least one natural and/or synthetic high-potency sweetener at least one carbohydrate, at least one polyol, and at least one amino acid
  • At least one natural and/or synthetic high-potency sweetener at least one polyol, at least one amino acid, and at least one other sweet taste improving additive;
  • At least one natural and/or synthetic high-potency sweetener at least one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive.
  • the sweet taste improving composition is selected from the group consisting of polyols, carbohydrates, amino acids, other sweet taste improving additives, and combinations thereof.
  • the other sweet taste improving additives useful in embodiments of this invention are described hereinabove.
  • a single sweet taste improving composition may be used with a single natural or synthetic high-potency sweetener and at least one preservative.
  • a single sweet taste improving composition may be used with one or more natural and/or synthetic high-potency sweeteners and at least one preservative.
  • one or more sweet taste improving compositions may be used with a single natural or synthetic high-potency sweetener and at least one preservative.
  • sweet taste improving compositions used in combination with one or more natural and/or synthetic high-potency sweeteners and at least one preservative.
  • sweet taste improving composition combinations for embodiments of this invention include: i. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive; ii. at least one polyol, at least one carbohydrate, and at least one other sweet taste improving additive; iii. at least one polyol and at least one other sweet taste improving additive; iv. at least one polyol and at least one carbohydrate; v. at least one carbohydrate and at least one other sweet taste improving additive; vi. at least one polyol and at least one amino acid; vii. at least one carbohydrate and at least one amino acid; viii. at least one amino acid and at least one other sweet taste improving additive.
  • sweet taste improving composition combinations in accordance with embodiments of this invention include:
  • 20 at least one polyol, at least one carbohydrate, and at least one nucleotide, and at least one other sweet taste improving additive;
  • 21 at least one polyol, at least one carbohydrate, and at least one organic acid, and at least one other sweet taste improving additive;
  • At least one polyol at least one carbohydrate, at least one amino acid, and at least one polyamino acid;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, and at least one sugar acid;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, and at least one nucleotide;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, and at least one organic acid;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, and at least one inorganic acid;
  • 35 at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, and at least one bitter compound; 36. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, and at least one polymer;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, and at least one protein or protein hydrolysate;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, and at least one surfactant;
  • At least one polyol at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, at least one flavonoid, and at least one alcohol;
  • At least one polyol at least one carbohydrate, at least one amino acid, and at least one organic acid;
  • At least one polyol at least one carbohydrate, at least one amino acid, and at least one inorganic acid;
  • At least one polyol at least one carbohydrate, at least one amino acid, and at least one alcohol;
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one nucleotide
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one inorganic acid;
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one protein or protein hydrolysate;
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one surfactant
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one flavonoid
  • At least one polyol at least one carbohydrate, at least one polyamino acid, and at least one alcohol;
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one nucleotide
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one organic acid;
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one inorganic acid
  • 64. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one bitter compound
  • 65 at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one polymer;
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one protein or protein hydrolysate;
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one surfactant
  • At least one polyol at least one carbohydrate, at least one sugar acid, and at least one alcohol
  • At least one polyol at least one carbohydrate, at least one nucleotide, and at least one inorganic acid
  • At least one polyol at least one carbohydrate, at least one nucleotide, and at least one polymer
  • At least one polyol at least one carbohydrate, at least one nucleotide, and at least one protein or protein hydrolysate;
  • At least one polyol at least one carbohydrate, at least one nucleotide, and at least one flavonoid
  • At least one polyol at least one carbohydrate, at least one nucleotide, and at least one alcohol;
  • At least one polyol at least one carbohydrate, at least one organic acid, and at least one surfactant
  • At least one polyol at least one carbohydrate, at least one organic acid, and at least one alcohol
  • At least one polyol at least one carbohydrate, at least one inorganic acid, and at least one alcohol;
  • At least one polyol at least one carbohydrate, at least one protein or protein hydrolysate, and at least one surfactant;
  • At least one polyol at least one carbohydrate, at least one flavonoid, and at least one alcohol.
  • sweet taste improving composition combinations in accordance with embodiments of this invention include:
  • At least one polyol and at least one organic salt 17. at least one polyol and at least one protein or protein hydrolysate or mixture of low molecular weight amino acids;
  • At least one polyol, at least one sugar acid, and at least one other sweet taste improving additive at least one polyol, at least one sugar acid, and at least one other sweet taste improving additive
  • At least one polyol, at least one nucleotide, and at least one other sweet taste improving additive at least one polyol, at least one nucleotide, and at least one other sweet taste improving additive
  • At least one polyol, at least one organic acid, and at least one other sweet taste improving additive at least one polyol, at least one organic acid, and at least one other sweet taste improving additive
  • At least one polyol, at least one inorganic acid, and at least one other sweet taste improving additive at least one polyol, at least one inorganic acid, and at least one other sweet taste improving additive
  • At least one polyol, at least one bitter compound, and at least one other sweet taste improving additive at least one polyol, at least one bitter compound, and at least one other sweet taste improving additive
  • At least one polyol at least one flavorant or flavoring ingredient, and at least one other sweet taste improving additive;
  • At least one polyol, at least one surfactant, and at least one other sweet taste improving additive are 28. at least one polyol, at least one surfactant, and at least one other sweet taste improving additive;
  • At least one polyol, at least one flavonoid, and at least one other sweet taste improving additive at least one polyol, at least one flavonoid, and at least one other sweet taste improving additive
  • At least one polyol, at least one alcohol, and at least one other sweet taste improving additive at least one polyol, at least one alcohol, and at least one other sweet taste improving additive
  • At least one polyol at least one amino acid, at least one polyamino acid, and at least one sugar acid;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, and at least one nucleotide
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, and at least one inorganic acid;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, and at least one bitter compound;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, and at least one polymer;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, and at least one protein or protein hydrolysate;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, and at least one surfactant;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, and at least one flavonoid;
  • At least one polyol at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, at least one flavonoid, and at least one alcohol;
  • At least one polyol, at least one polyamino acid, and at least one organic salt are 55. at least one polyol, at least one polyamino acid, and at least one organic salt
  • At least one polyol at least one polyamino acid, and at least one surfactant
  • At least one polyol, at least one sugar acid, and at least one surfactant at least one polyol, at least one sugar acid, and at least one surfactant
  • 77 at least one polyol, at least one nucleotide, and at least one protein or protein hydrolysate; 78. at least one polyol, at least one nucleotide, and at least one surfactant;
  • At least one polyol, at least one polymer, and at least one surfactant are 100. at least one polyol, at least one polymer, and at least one surfactant;
  • At least one polyol at least one protein or protein hydrolysate, and at least one surfactant
  • At least one polyol at least one protein or protein hydrolysate, and at least one flavonoid
  • 105 at least one polyol, at least one surfactant, and at least one flavonoid
  • 106 at least one polyol, at least one surfactant, and at least one alcohol
  • At least one sweet taste improving additive and erythritol at least one sweet taste improving additive and erythritol
  • At least one sweet taste improving additive and maltitol at least one sweet taste improving additive and maltitol
  • At least one sweet taste improving additive and lactitol At least one sweet taste improving additive and lactitol
  • At least one sweet taste improving additive and isomalt At least one sweet taste improving additive and isomalt
  • At least one sweet taste improving additive and glycerol at least one sweet taste improving additive and glycerol
  • At least one sweet taste improving additive and palatinose at least one sweet taste improving additive and palatinose
  • At least one sweet taste improving additive and reduced maltose syrup at least one sweet taste improving additive and reduced maltose syrup
  • At least one sweet taste improving additive at least one sweet taste improving additive, erythritol, and at least one other polyol
  • At least one sweet taste improving additive maltitol, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, mannitol, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, sorbitol, and at least one other polyol
  • At least one sweet taste improving additive lactitol, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, xylitol, and at least one other polyol
  • At least one sweet taste improving additive propylene glycol, and at least one other polyol
  • At least one sweet taste improving additive glycerol, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, palatinose, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, reduced isomalto-oligosaccharides, and at least one other polyol; 134. at least one sweet taste improving additive, reduced xylo-oligosaccharides, and at least one other polyol;
  • At least one sweet taste improving additive at least one sweet taste improving additive, reduced gentio-oligosaccharides, and at least one other polyol;
  • At least one sweet taste improving additive at least one sweet taste improving additive, reduced maltose syrup, and at least one other polyol
  • At least one sweet taste improving additive at least one sweet taste improving additive, reduced glucose syrup, and at least one other polyol.
  • sweet taste improving composition combinations in accordance with embodiments of this invention include:
  • At least one polyol and high fructose corn syrup e.g. HFCS55 and HFCS42
  • starch syrup e.g. HFCS55 and HFCS42
  • 1 19. at least one polyol, maltotetraose, and at least one other carbohydrate;
  • 129. at least one polyol, high fructose corn syrup (e.g. HFCS55 and HFCS42) or starch syrup, and at least one other carbohydrate;
  • high fructose corn syrup e.g. HFCS55 and HFCS42
  • starch syrup e.g. HFCS55 and HFCS42
  • At least one carbohydrate, mannitol, and at least one other polyol At least one carbohydrate, mannitol, and at least one other polyol
  • At least one carbohydrate, reduced glucose syrup, and at least one other polyol at least one carbohydrate, reduced glucose syrup, and at least one other polyol.
  • sweet taste improving composition combinations in accordance with embodiments of this invention include:
  • At least one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive are 17. at least one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive;
  • At least one carbohydrate, at least one nucleotide, and at least one other sweet taste improving additive at least one carbohydrate, at least one nucleotide, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one organic acid, and at least one other sweet taste improving additive at least one carbohydrate, at least one organic acid, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one inorganic acid, and at least one other sweet taste improving additive at least one carbohydrate, at least one inorganic acid, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one bitter compound, and at least one other sweet taste improving additive at least one carbohydrate, at least one bitter compound, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one polymer, and at least one other sweet taste improving additive are 25. at least one carbohydrate, at least one polymer, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one surfactant, and at least one other sweet taste improving additive at least one carbohydrate, at least one surfactant, and at least one other sweet taste improving additive
  • At least one carbohydrate, at least one alcohol, and at least one other sweet taste improving additive at least one carbohydrate, at least one alcohol, and at least one other sweet taste improving additive
  • At least one carbohydrate at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, and at least one inorganic acid
  • 35. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, and at least one bitter compound
  • At least one carbohydrate, at least one amino acid, and at least one flavonoid 50. at least one carbohydrate, at least one amino acid, and at least one alcohol;
  • At least one carbohydrate, at least one polyamino acid, and at least one bitter compound At least one carbohydrate, at least one polyamino acid, and at least one bitter compound
  • At least one carbohydrate, at least one sugar acid, and at least one bitter compound At least one carbohydrate, at least one sugar acid, and at least one bitter compound
  • 70 at least one carbohydrate, at least one nucleotide, and at least one organic acid;
  • At least one carbohydrate, at least one nucleotide, and at least one surfactant At least one carbohydrate, at least one nucleotide, and at least one surfactant
  • At least one sweet taste improving additive and trehalose at least one sweet taste improving additive and trehalose
  • At least one sweet taste improving additive and cyclodextrin at least one sweet taste improving additive and cyclodextrin
  • At least one sweet taste improving additive and ⁇ -cyclodextrin at least one sweet taste improving additive and ⁇ -cyclodextrin
  • At least one sweet taste improving additive and maltodextrin At least one sweet taste improving additive and maltodextrin
  • At least one sweet taste improving additive and fructose At least one sweet taste improving additive and fructose
  • At least one sweet taste improving additive and threose At least one sweet taste improving additive and threose
  • At least one sweet taste improving additive and lyxose at least one sweet taste improving additive and lyxose
  • At least one sweet taste improving additive and allose at least one sweet taste improving additive and allose
  • At least one sweet taste improving additive and idose at least one sweet taste improving additive and idose
  • At least one sweet taste improving additive and talose 125. at least one sweet taste improving additive and talose
  • At least one sweet taste improving additive and lactose at least one sweet taste improving additive and lactose
  • At least one sweet taste improving additive and maltose at least one sweet taste improving additive and maltose
  • At least one sweet taste improving additive and invert sugar At least one sweet taste improving additive and invert sugar
  • At least one sweet taste improving additive and isotrehalose at least one sweet taste improving additive and isotrehalose
  • At least one sweet taste improving additive and neotrehalose at least one sweet taste improving additive and neotrehalose
  • At least one sweet taste improving additive and galactose at least one sweet taste improving additive and galactose
  • At least one sweet taste improving additive and beet oligosaccharides at least one sweet taste improving additive and beet oligosaccharides
  • At least one sweet taste improving additive and isomalto-oligosaccharides at least one sweet taste improving additive and isomalto-oligosaccharides
  • At least one sweet taste improving additive and xylotriose at least one sweet taste improving additive and xylotriose
  • At least one sweet taste improving additive and xylobiose at least one sweet taste improving additive and xylobiose
  • At least one sweet taste improving additive and gentiobiose at least one sweet taste improving additive and gentiobiose
  • At least one sweet taste improving additive and gentiotriose at least one sweet taste improving additive and gentiotriose
  • At least one sweet taste improving additive and gentiotetraose at least one sweet taste improving additive and gentiotetraose
  • At least one sweet taste improving additive and sorbose at least one sweet taste improving additive and sorbose
  • At least one sweet taste improving additive and nigero-oligosaccharides 147. at least one sweet taste improving additive and nigero-oligosaccharides
  • At least one sweet taste improving additive and fructooligosaccharides At least one sweet taste improving additive and fructooligosaccharides
  • At least one sweet taste improving additive and kestose at least one sweet taste improving additive and kestose
  • At least one sweet taste improving additive and nystose at least one sweet taste improving additive and nystose
  • At least one sweet taste improving additive and maltotetraol at least one sweet taste improving additive and maltotetraol
  • At least one sweet taste improving additive and malto-oligosaccharides 155. at least one sweet taste improving additive and malto-oligosaccharides
  • At least one sweet taste improving additive and maltotetraose at least one sweet taste improving additive and maltotetraose
  • At least one sweet taste improving additive and maltopentaose at least one sweet taste improving additive and maltopentaose
  • At least one sweet taste improving additive and maltohexaose at least one sweet taste improving additive and maltohexaose
  • At least one sweet taste improving additive and maltoheptaose At least one sweet taste improving additive and maltoheptaose
  • At least one sweet taste improving additive and lactulose at least one sweet taste improving additive and lactulose
  • At least one sweet taste improving additive and melibiose at least one sweet taste improving additive and melibiose
  • At least one sweet taste improving additive and raffinose at least one sweet taste improving additive and raffinose
  • At least one sweet taste improving additive and rhamnose at least one sweet taste improving additive and rhamnose
  • At least one sweet taste improving additive and ribose at least one sweet taste improving additive and ribose
  • At least one sweet taste improving additive and high fructose corn syrup e.g., HFCS55 and HFCS42
  • high fructose corn syrup e.g., HFCS55 and HFCS42
  • starch syrup e.g., HFCS55 and HFCS42
  • At least one sweet taste improving additive and soybean oligosaccharides At least one sweet taste improving additive and glucose syrup;
  • At least one sweet taste improving additive D-tagatose, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, trehalose, and at least one other carbohydrate
  • At least one sweet taste improving additive D-galactose, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, rhamnose, and at least one other carbohydrate
  • At least one sweet taste improving additive, dextrin, and at least one other carbohydrate 17. at least one sweet taste improving additive, dextrin, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, cyclodextrin, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, ⁇ -cyclodextrin, and at least one other carbohydrate
  • At least one sweet taste improving additive maltodextrin, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, dextran, and at least one other carbohydrate
  • At least one sweet taste improving additive sucrose, and at least one other carbohydrate
  • At least one sweet taste improving additive glucose, and at least one other carbohydrate
  • At least one sweet taste improving additive fructose, and at least one other carbohydrate
  • At least one sweet taste improving additive threose, and at least one other carbohydrate
  • At least one sweet taste improving additive arabinose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, xylose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, lyxose, and at least one other carbohydrate; 187. at least one sweet taste improving additive, allose, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, altrose, and at least one other carbohydrate
  • At least one sweet taste improving additive idose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, talose, and at least one other carbohydrate;
  • At least one sweet taste improving additive lactose, and at least one other carbohydrate
  • At least one sweet taste improving additive maltose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, invert sugar, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, trehalose, and at least one other carbohydrate
  • At least one sweet taste improving additive isotrehalose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, neotrehalose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, palatinose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, galactose, and at least one other carbohydrate
  • At least one sweet taste improving additive beet oligosaccharides, and at least one other carbohydrate
  • At least one sweet taste improving additive isomalto-oligosaccharides, and at least one other carbohydrate
  • At least one sweet taste improving additive isomaltose, and at least one other carbohydrate
  • At least one sweet taste improving additive isomaltotriose, and at least one other carbohydrate
  • at least one sweet taste improving additive panose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, xylo-oligosaccharides, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, xylotriose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, xylobiose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, gentio-oligoscaccharides, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, gentiobiose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, gentiotriose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, gentiotetraose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, sorbose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, nigero-oligosaccharides, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, palatinose oligosaccharides, and at least one other carbohydrate;
  • At least one sweet taste improving additive, fucose, and at least one other carbohydrate at least one sweet taste improving additive, fucose, and at least one other carbohydrate
  • At least one sweet taste improving additive fructooligosaccharides, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, kestose, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, nystose, and at least one other carbohydrate
  • At least one sweet taste improving additive maltotetraol, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, maltotriol, and at least one other carbohydrate; 221. at least one sweet taste improving additive, malto-oligosaccharides, and at least one other carbohydrate;
  • At least one sweet taste improving additive maltotriose, and at least one other carbohydrate
  • At least one sweet taste improving additive maltotetraosc, and at least one other carbohydrate
  • At least one sweet taste improving additive maltopentaose, and at least one other carbohydrate
  • At least one sweet taste improving additive maltohexaose, and at least one other carbohydrate
  • At least one sweet taste improving additive maltoheptaose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, lactulose, and at least one other carbohydrate;
  • At least one sweet taste improving additive me ⁇ biose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, raffinose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, rhamnose, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, ribose, and at least one other carbohydrate;
  • At least one sweet taste improving additive isomerized liquid sugars, and at least one other carbohydrate
  • At least one sweet taste improving additive at least one sweet taste improving additive, high fructose corn syrup (e.g. HFCS5S and HFCS42) or starch syrup, and at least one other carbohydrate;
  • At least one sweet taste improving additive at least one sweet taste improving additive, coupling sugars, and at least one other carbohydrate;
  • At least one sweet taste improving additive soybean oligosaccharides, and at least one other carbohydrate
  • the sweetener composition comprises at least one natural and/or synthetic high-potency sweetener and at least one preservative in combination with a plurality of sweet taste improving additives, desirably 3 or more sweet taste improving additives, and even more desirably 4 or more sweet taste improving additives, wherein each sweet taste improving additive is present in an amount such that no one sweet taste improving additive imparts a substantial off taste to the sweetener composition.
  • the amounts of the sweet taste improving additives in the sweetener composition are balanced so that no one sweet taste improving additive imparts a substantial off taste to the sweetener composition.
  • the sweetener composition provided herein comprises at least one sweet taste improving composition in the sweetener composition in an amount effective for the sweetener composition to impart an osmolarity of at least 10 mOsmoles/L to an aqueous solution of the sweetener composition, wherein the at least one natural and/or synthetic high-potency sweetener is present in the aqueous solution in an amount sufficient to impart a maximum sweetness intensity equivalent to that of a 10% aqueous solution of sucrose by weight.
  • mOsmoles/L refers to milliosmoles per liter.
  • the sweetener composition comprises at least one sweet taste improving composition in an amount effective for the sweetener composition to impart an osmolarity of 10 to 500 mOsmoles/L, preferably 25 to 500 mOsmoles/L preferably, more preferably 100 to 500 mOsmoles/L, more preferably 200 to 500 mOsmoles/L, and still more preferably 300 to 500 mOsmoles/L to an aqueous solution of the sweetener composition, wherein the at least one natural and/or synthetic high- potency sweetener is present in the aqueous solution in an amount sufficient to impart a maximum sweetness intensity equivalent to that of a 10% aqueous solution of sucrose by weight.
  • Osmolarity refers to the measure of osmoles of solute per liter of solution, wherein osmole is equal to the number of moles of osmotically active particles in an ideal solution (e.g., a mole of glucose is one osmole), whereas a mole of sodium chloride is two osmoles (one mole of sodium and one mole of chloride).
  • suitable sweet taste improving carbohydrate additives for the present invention have a molecular weight less than or equal to 500 and desirably have a molecular weight from 50 to 500.
  • suitable carbohydrates with a molecular weight less than or equal to 500 include, but are not limited to, sucrose, fructose, glucose, maltose, lactose, mannose, galactose, and tagatose.
  • a sweet taste improving carbohydrate additive is present in the sweetener compositions in an amount from about 1,000 to about 100,000 ppm.
  • ppm means parts per million by weight or volume.
  • 500 ppm means 500 mg in a liter.
  • a sweet taste improving carbohydrate additive is present in the sweetened compositions in an amount from about 2,500 to about 10,000 ppm.
  • suitable sweet taste improving carbohydrate additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500.
  • suitable sweet taste improving polyol additives have a molecular weight less than or equal to 500 and desirably have a molecular weight from 76 to 500.
  • suitable sweet taste improving polyol additives with a molecular weight less than or equal to 500 include, but are not limited to, erythritol, glycerol, and propylene glycol.
  • a sweet taste improving polyol additive is present in the sweetener compositions in an amount from about 100 ppm to about 80,000 ppm.
  • a sweet taste improving polyol additive is present in sweetened compositions in an amount from about 400 to about 80,000 ppm.
  • suitable sweet taste improving polyol additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving polyol additives with a molecular weight ranging from about 76 to about 500.
  • a sweet taste improving polyol additive is present in sweetener compositions in an amount from about 400 to about 80,000 ppm of the total sweetener composition, more particularly from about about 5,000 to about 40,000 ppm, and still more particularly from about 10,000 to about 35,000 ppm.
  • the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving polyol additive are present in the sweetener composition in a ratio from about 1 :4 to about 1 :800, respectively; more particularly from about 1 :20 to about 1 :600; even more particularly from about 1:50 to about 1 :300; and still more particularly from about 1:75 to about 1 :150.
  • a suitable sweet taste improving alcohol additive is present in the sweetener compositions in an amount from about 625 to about 10,000 ppm.
  • suitable sweet taste improving alcohol additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving alcohol additives with a molecular weight ranging from about 46 to about 500.
  • a non-limiting example of sweet taste improving alcohol additive with a molecular weight ranging from about 46 to about 500 includes ethanol.
  • suitable sweet taste improving amino acid additives have a molecular weight of less than or equal to 250 and desirably have a molecular weight from 75 to 250.
  • suitable sweet taste improving amino acid additives with a molecular weight less than or equal to 250 include, but are not limited to, glycine, alanine, serine, valine, leucine, isoleucine, proline, theanine, and threonine.
  • Preferred sweet taste improving amino acid additives include those which are sweet tasting at high concentrations, but desirably are present in embodiments of this invention at amounts below or above their sweetness taste detection threshold. Even more preferred are mixtures of sweet taste improving amino acid additives at amounts below or above their sweetness taste detection threshold.
  • a sweet taste improving amino acid additive is present in the sweetener compositions in an amount from about 100 ppm to about 25,000 ppm, more particularly from about 1,000 to about 10,000 ppm, and stili more particularly from about 2,500 to about 5,000 ppm. In accordance with other desirable embodiments of this invention, a sweet taste improving amino acid additive is present in the sweetened compositions in an amount from about 250 ppm to about 7,500 ppm.
  • suitable sweet taste improving amino acid additives for imparting osmolarities ranging from about 10 inOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving amino acid additives with a molecular weight ranging from about 75 to about 250.
  • a suitable sweet taste improving amino acid salt additive is present in the sweetener compositions in an amount from about 25 to about 10,000 ppm, more particularly from about 1,000 to about 7,500 ppm, and still more particularly from about 2,500 to about 5,000 ppm.
  • suitable sweet taste improving amino acid salt additives for imparting osmolalities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300.
  • sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300 include salts of glycine, alanine, serine, theaninc, and threonine.
  • a suitable sweet taste improving protein or protein hydroyslate additive is present in the sweetener compositions in an amount from about 200 to about 50,000 ppm.
  • suitable sweet taste improving protein or protein hydrolysate additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300.
  • Non-limiting examples of sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300 include proteins or protein hydrolysates containing glycine, alanine, serine, and threonine.
  • a suitable sweet taste improving inorganic acid additive is present in the sweetener compositions in an amount from about 25 to about 5,000 ppm.
  • suitable sweet taste improving inorganic acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, phosphoric acid, HCI, and H 2 SO 4 and any other inorganic acid additives which are safe for human or animal consumption when used in a generally acceptable range.
  • suitable sweet taste improving inorganic acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving inorganic acid additives with a molecular weight range from about 36 to about 98.
  • a suitable sweet taste improving inorganic acid salt additive is present in the sweetener compositions in an amount from about 25 to about 5,000 ppm.
  • suitable sweet taste improving inorganic acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, salts of inorganic acids, for example sodium, potassium, calcium, and magnesium salts of phosphoric acid, and any other alkali or alkaline earth metal salts of other inorganic acids (e.g., sodium bisulfate) which are safe for human or animal consumption when used in a generally acceptable range.
  • suitable suitable sweet taste improving inorganic acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving inorganic acid salt additives with a molecular weight range from about 58 to about 120.
  • a suitable sweet taste improving organic acid additive is present in the sweetener compositions in an amount from about 10 to about 5,000 ppm.
  • suitable sweet taste improving organic acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, creatine, citric acid, malic acid, succinic acid, hydroxycitric acid, tartaric acid, fumaric acid, gluconic acid, glutaric acid, adipic acid, and any other sweet taste improving organic acid additives which are safe for human or animal consumption when used in a generally acceptable range.
  • the sweet taste improving organic acid additive comprises a molecular weight range from about 60 to about 208.
  • a suitable sweet taste improving organic acid salt additive is present in the sweetener compositions in an amount from about 20 to about 10,000 ppm.
  • suitable sweet taste improving organic acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, salts of sweet taste improving organic acid additives, such as sodium, potassium, calcium, magnesium, and other alkali or alkaline metal salts of citric acid, malic acid, tartaric acid, fumaric acid, gluconic acid, glutaric acid, adipic acid, hydroxycitric acid, succinic acid, and salts of any other sweet taste improving organic acid additives which are safe for human or animal consumption when used in a generally acceptable range.
  • the sweet taste improving organic acid salt additive comprises a molecular weight range from about ] 40 to about 208.
  • a suitable sweet taste improving organic base salt additive is present in the sweetener compositions in an amount from about 10 to about 5,000 ppm.
  • suitable sweet taste improving organic base salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, inorganic and organic acid salts of organic bases such as glucosamine salts, choline salts, and guanidine salts.
  • a suitable sweet taste improving astringent additive is present in the sweetener compositions in an amount from about 25 to about 1,000 ppm.
  • suitable sweet taste improving astringent additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, tannic acid, tea polyphenols, catechins, aluminum sulfate, AlNa(SO ⁇ , AlK(SO ⁇ and other forms of alum,
  • a suitable sweet taste improving nucleotide additive is present in the sweetener compositions in an amount from about 5 to about 1,000 ppm.
  • suitable sweet taste improving nucleotide additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, adenosine monophosphate.
  • a suitable sweet taste improving polyamino acid additive is present in the sweetener compositions in an amount from about 30 to about 2,000 ppm.
  • suitable sweet taste improving polyamino acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, poIy-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), poly-L- ornithine (e.g., poly-L- ⁇ -ornithine or poly-L- ⁇ -ornithine), and poly-L-arginine.
  • a suitable sweet taste improving polymer additive is present in the sweetener compositions in an amount from about 30 to about 2,000 ppm.
  • suitable sweet taste improving polymer additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, chitosan, sodium hexametaphosphate and its salts, pectin, hydrocolloids such as gum acacia Senegal, propylene glycol, polyethylene glycol, and polyethylene glycol methyl ether).
  • a suitable sweet taste improving surfactant additive is present in the sweetener compositions in an amount from about 1 to about 5,000 ppm.
  • suitable sweet taste improving surfactant additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but arc not limited to, polysorbates, choline chloride, sodium taurocholate, lecithins, sucrose oleate esters, sucrose stearate esters, sucrose palmitate esters, and sucrlose laurate esters.
  • a suitable sweet taste improving flavonoid additive is present in the sweetener compositions in an amount from about 0.1 to about 1,000 ppm.
  • suitable sweet taste improving flavonoid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, naringin, catechins, rutins, neohesperidin, and neohesperidin dihydrochalcone.
  • non-limiting examples of sweet taste improving compositions enhancing the natural and/or synthetic high-potency sweetener's osmotic taste to be more sugar-like include sweet taste improving carbohydrate additives, sweet taste improving alcohol additives, sweet taste improving polyol additives, sweet taste improving amino acid additives, sweet taste improving amino acid salt additives, sweet taste improving inorganic acid salt additives, sweet taste improving polymer additives, and sweet taste improving protein or protein hydrolysate additives.
  • suitable sweet taste improving carbohydrate additives for improving the osmotic taste of the natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500.
  • sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500 include sucrose, fructose, glucose, maltose, lactose, mannose, galactose, ribose, rhamnose, trehalose, HFCS, and tagatose.
  • suitable sweet taste improving polyol additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving polyol additives with a molecular weight ranging from about 76 to about 500.
  • sweet taste improving polyol additives with a molecular weight ranging from about 76 to about 500 include erythritol, glycerol, and propylene glycol.
  • other suitable sweet taste improving polyol additives include sugar alcohols.
  • suitable sweet taste improving alcohol additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving alcohol additives with a molecular weight ranging from about 46 to about 500.
  • sweet taste improving alcohol additive with a molecular weight ranging from about 46 to about 500 includes ethanol.
  • suitable sweet taste improving amino acid additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving amino acid additives with a molecular weight ranging from about 75 to about 250.
  • sweet taste improving amino acid additives with a molecular weight ranging from about 75 to about 250 include glycine, alanine, serine, leucine, valine, isoleucine, proline, hydroxyproline, glutamine, theanine, and threonine.
  • suitable sweet taste improving amino acid salt additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300.
  • sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300 include salts of glycine, alanine, serine, leucine, valine, isoleucine, proline, hydroxyproline, glutamine, theanine, and threonine.
  • suitable sweet taste improving protein or protein hydrolysate additives for improving the osmotic taste of natural and/or synthetic high- potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300.
  • suitable sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300 include protein or protein hydrolysates containing glycine, alanine, serine, leucine, valine, isoleucine, proline, and threonine.
  • suitable sweet taste improving inorganic acid salt additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sodium chloride, potassium chloride, magnesium chloride, KH 2 PO4 and NaH 2 P ⁇ 4.
  • Suitable sweet taste improving inorganic acid salt additives for improving the osmotic taste may comprise a molecular weight from about 58 to about 120.
  • suitable sweet taste improving bitter additives for improving the osmotic taste of the natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, caffeine, quinine, urea, quassia, tannic acid, and naringin.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive chosen from inosine monophosphate ("IMP"), guanosine monophosphate (“GMP”), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof.
  • nucleotide additive chosen from inosine monophosphate ("IMP"), guanosine monophosphate (“GMP”), adenosine monophosphate (“
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ -cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose,
  • carbohydrate additive chosen from taga
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo- oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup.
  • polyol additive chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving amino acid additive chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, carnitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or salts thereof.
  • amino acid additive chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leu
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyamino acid additive chosen from poly-L-aspartic acid, poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), poly-L- ornithine (e.g., poly-L- ⁇ -ornithine or poly-L- ⁇ -ornithine), poly-L-arginine, other polymeric forms of amino acids, or salts thereof.
  • polyamino acid additive chosen from poly-L-aspartic acid, poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), poly-L- ornithine (e.g., poly-L- ⁇ -ornithine or poly-L- ⁇ -ornithine), poly-L-arginine, other polymeric forms
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving sugar acid additive chosen from aldonic, uronic, aldaric, alginic, gluconic, glucuronic, glucaric, galactaric, galacturonic, or salts thereof.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving organic acid additive chosen from C2- C30 carboxylic acids, substituted hydroxyl C 1-C30 carboxylic acids, benzoic acid, substituted benzoic acids (e.g., 2,4-dihydroxybenzoic acid), substituted cinnamic acids, hydroxyacids, substituted hydroxybenzoic acids, substituted cyclohexyl carboxyJic acids, tannic acid, lactic acid, tartaric acid, citric acid, gluconic acid, glucoheptonic acids, glutaric acid, creatine, adipic acid, hydroxycitric acid, malic acid, fruitaric acid, fumaric acid, maleic acid, succinic acid, chlorogenic acid, salicylic acid, caffeic acid, bile acids, acetic acid, ascorbic acid, alginic
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving inorganic acid additive chosen from phosphoric acid, phosphorous acid, polyphosphoric acid, hydrochloric acid, sulfuric acid, carbonic acid, sodium dihydrogen phosphate, or salts thereof.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving bitter compound additive chosen from caffeine, quinine, urea, bitter orange oil, naringin, quassia, or salts thereof.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving flavorant additive chosen from vanillin, vanilla extract, mango extract, cinnamon, citrus, coconut, ginger, viridiflorol, almond, menthol, grape skin extract, or grape seed extract.
  • the at least one sweet taste improving flavorant additive comprises a proprietary sweetener chosen from DOhlerTM Natural Flavoring Sweetness Enhancer K 14323 (DOhlerTM, Darmstadt, Germany), SymriseTM Natural Flavor Mask for Sweeteners 161453 or 164126 (SymriseTM, Holzminden, Germany), Natural AdvantageTM Bitterness Blockers 1 , 2, 9 or 10 (Natural AdvantageTM, Freehold, New Jersey, U.S.A.), or SucramaskTM (Creative Research Management, Stockton, California, U.S.A.)
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polymer additive chosen from chitosan, pectin, pectic, pectinic, polyuronic, polygalacturonic acid, starch, food hydrocolloid or crude extracts thereof (e.g., gum acacia Senegal, gum acacia seyal, carageenan), poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), polyornithine (e.g., poly-L- ⁇ -ornithine or poly- ⁇ - ornithine), polypropylene glycol, polyethylene glycol, poly(ethylene glycol methyl ether), polyarginine, polyaspartic acid, polyglutamic acid, polyethyleneimine, alginic acid, sodium alginate, propylene glycol
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving protein hydrolysate additive chosen from bovine serum albumin (BSA), whey protein (including fractions or concentrates thereof such as 90% instant whey protein isolate, 34% whey protein, 50% hydrolyzed whey protein, and 80% whey protein concentrate), soluble rice protein, soy protein, protein isolates, protein hydrolysates, reaction products of protein hydrolysates, glycoproteins, and/or proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, theanine, asparagine, glutamine, arginine, valine, isoleucine, leucine, norvaline, methionine, proline, tyrosine, hydroxyproline, or the like).
  • BSA bovine serum albumin
  • whey protein including fractions or concentrates thereof such
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving surfactant additive chosen from polysorbates (e.g., polyoxyethylene sorbitan monooleate (polysorbate 80), polysorbate 20, polysorbate 60), sodium dodecylbenzenesulfonate, dioctyl sulfosuccinate or dioctyl sulfosuccinate sodium, sodium dodecyl sulfate, cetylpyridinium chloride, hexadecyltrimethylammonium bromide, sodium cholate, carbamoyl, choline chloride, sodium glycocholate, sodium taurocholate, sodium taurodeoxycholate, lauric arginate, sodium stearoyl lactylate, lecithins, sucrose oleate esters, sucrose stearate esters, suc
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving flavonoid additive chosen from catechins, polyphenols, rutins, neohesperidin, naringin, neohesperidin dihydrochalcone, or the like.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with ethanol.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving astringent compound additive chosen from tannic acid, europium chloride (EuCh), gadolinium chloride (GdCb), terbium chloride (TbCb), alum, tannic acid, and polyphenols (e.g., tea polyphenol).
  • astringent compound additive chosen from tannic acid, europium chloride (EuCh), gadolinium chloride (GdCb), terbium chloride (TbCb), alum, tannic acid, and polyphenols (e.g., tea polyphenol).
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving inorganic salt additive chosen from sodium chloride, potassium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium citrate, europium chloride (EuCb), gadolinium chloride (GdCb) 1 terbium chloride (TbCb), magnesium sulfate, magnesium phosphate, alum, magnesium chloride, mono-, di-, tri-basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium carbonate, sodium bisulfate, or sodium bicarbonate.
  • at least one sweet taste improving inorganic salt additive chosen from sodium chloride, potassium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium citrate, europium chloride (EuCb), gadolinium chloride (GdCb) 1 terbium chloride (TbCb), magnesium
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving organic salt additive chosen from choline chloride, gluconic acid sodium salt, gluconic acid potassium salt, guanidine HCI, amiloride HCl, glucosamine HCl, monosodium glutamate (MSG), adenosine monophosphate salt, magnesium gluconate, potassium tartrate, and sodium tartrate.
  • organic salt additive chosen from choline chloride, gluconic acid sodium salt, gluconic acid potassium salt, guanidine HCI, amiloride HCl, glucosamine HCl, monosodium glutamate (MSG), adenosine monophosphate salt, magnesium gluconate, potassium tartrate, and sodium tartrate.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive, at least one sweet taste improving carbohydrate additive, and at least one sweet taste improving amino acid additive; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof
  • IMP inosine mono
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive and at least one sweet taste improving carbohydrate additive; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate (“GMP”), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one carbohydrate
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive and at least one sweet taste improving polyol additive; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, gua ⁇ osine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one poly
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive and at least one sweet taste improving amino acid; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP”), adenosine monophosphate (“AMP”), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one amino acid additive is chosen
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive, at least one sweet taste improving polyol additive, and at least one sweet taste improving amino acid additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ -cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM).
  • the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ -cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (
  • dextran sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-Iactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving polyol additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ - cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving amino acid additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ - cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as FibersoI-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving amino acid additive; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one amino acid additive is chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving inorganic salt additive; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one inorganic salt additive is chosen from sodium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium citrate, euro
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving inorganic salt additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodextrin, ⁇ - cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive, at least one sweet taste improving amino acid additive, and at least one sweet taste improving inorganic salt additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., ⁇ -cyclodcxtrin, ⁇ -cyclodextrin, and ⁇ -cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose,
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving polyamino acid additive; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one polyamino acid additive is chosen from poly-L-aspartic acid, poly-L-lysine (e.g.
  • a sweetener composition comprising at least one preservative and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving protein or protein hydrolysate additive and at Jeast one sweet taste improving inorganic salt additive; wherein the at least one sweet taste improving protein or protein hydrolysate additive is chosen from bovine serum albumin (BSA), whey protein (including fractions or concentrates thereof such as 90% instant whey protein isolate, 34% whey protein, 50% hydrolyzed whey protein, and 80% whey protein concentrate), soluble rice protein, soy protein, protein isolates, protein hydrolysates, reaction products of protein hydrolysates, glycoproteins, and/or proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, theanine, asparagine, glutamine, arginine, valine, isoleucine, leucine, norvaline, methion
  • BSA bovine serum albumin
  • a sweetener composition comprising at least one preservative and rebaudioside A in combination with at least one natural and/or synthetic high-potency sweetener other than rebaudioside-A and at least one sweet taste improving composition.
  • a sweetener composition comprising at least one preservative and rebaudioside A in combination with at least one synthetic high-potency sweetener, wherein the at least one synthetic high-potency sweetener functions as a sweet taste improving composition.
  • Non-limiting examples of suitable sweet taste improving synthetic sweetener additives include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalco ⁇ e, cyclamate, neotame, N-[N-[3- (3-hydroxy-4-methoxyphenyl)propyl]-L- ⁇ -as ⁇ artyl]-L-phenylalanine 1 -methyl ester, N-[N- [3-(3-hydroxy-4-methoxyphenyl)-3-methylbutyl]-L- ⁇ -aspartyl]-L-phenylalanine 1 -methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L- ⁇ -aspartyl]-L-phenylalanine 1 -methyl ester, salts thereof, and the like.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, cyclamate, saccharin, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving polyo! additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 ppm to about 25,000 ppm of the composition, and the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • the at least one sweet taste improving amino acid additive is glycine or alanine
  • the at least one sweet taste improving polyol additive is erythritol.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curciilin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving protein or protein hydrolysate additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition, and the at least one sweet taste improving protein or protein hydrolysate additive is present in an amount from about 200 ppm to about 50,000 ppm of the composition.
  • the at least one sweet taste improving amino acid additive is glycine or lysine
  • the at least one sweet taste improving protein or protein hydrolysate additive is a protein, a hydrolysate, or a reaction product of a hydrolysate of a protein containing glycine, alanine, serine, leucine, valine, isoleucine, proline, or threonine.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving protein or protein hydrolysate additive and at least one sweet taste improving polyol additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving protein or protein hydrolysate additive is present in an amount from about 200 ppm to about 50,000 ppm of the composition, and at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • the at least one sweet taste improving protein or protein hydrolysate additive is a protein, a hydrolysate, or a reaction product of a hydrolysate of proteins containing glycine, alanine, serine, leucine, valine, isoleucine, proline, or threonine, and the at least one sweet taste improving polyol additive is erythritol.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving carbohydrate additive is provided.
  • the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition.
  • the sweetener composition comprises REBA and glucose, sucrose, HFCS, or D-fructose in an amount from about 10,000 ppm to about 80,000 ppm of the composition.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotamc, in combination with at least one sweet taste improving polyol additive is provided.
  • the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • the at least one sweet taste improving polyol additive is present in an amount from about 5,000 to about 60,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV 1 mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with propylene glycol, erythritol, or combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV 1 mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA) (with at least 50 % REBA in a steviol glycoside mixture) in combination with at least one sweet taste improving polyol additive is provided.
  • the at least one sweet taste improving polyol additive comprises erythritol.
  • rebaudioside A is present in an amount from about 100 to about 3,000 ppm and the erythritol is present in an amount from about 400 to about 80,000 ppm of the total sweetener composition.
  • rebaudioside A is present in an amount from about 100 to about 3,000 ppm and the erythritol is present in an amount from about 5,000 to about 40,000 ppm of the total sweetener composition.
  • rebaudioside A is present in an amount from about 100 to about 3,000 ppm and the erythritol is present in an amount from about 10,000 to about 35,000 ppm of the total sweetener composition.
  • rebaudioside A and erythritol are present in the sweetener composition in a ratio from about 1 :4 to about 1 :800, respectively.
  • rebaudioside A and erythritol are present in the sweetener composition in a ratio from about 1 :20 to about 1 :600, respectively; more particularly from about 1 :50 to about 1:300; and still more particularly from about 1 :75 to about 1:150.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stcvia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, or curculin, in combination with at least one sweet taste improving synthetic sweetener additive is provided.
  • the sweetener composition comprises at least one preservative and a sweetener comprising rebaudioside-A (REBA) in combination with saccharin or acesulfame potassium or other salts in an amount from about 10 ppm to about 100 ppm of the composition.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo s ⁇ veetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving polyol additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition and at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • Non- limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with tagatose, fructose or sucrose and erythritol.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with tagatose, fructose
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neolame, in combination with at least one sweet taste improving inorganic salt additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neolame in combination with at least one sweet taste improving inorganic salt additive
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with NaCl, KCI, NaHSO 4 .H2O, NaH2PC»4, MgSO 4 , KAI(SO ⁇ (alum), magnesium phosphate, magnesium chloride, KCl and KH 2 PO 4 , or other combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • a particularly desirable embodiment comprises at least one preservative and a sweetener composition
  • a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with a mixture of inorganic salt additives, such as chlorides, phosphates, and sulfates of sodium, magnesium, potassium, and calcium (e.g., sodium chloride and potassium chloride; potassium phosphate and potassium chloride; sodium chloride and sodium phosphate; calcium phosphate and calcium sulfate; magnesium chloride and magnesium phosphate; and calcium phosphate, calcium sulfate, and potassium sulfate).
  • REBA rebaudioside-A
  • stevia stevioside
  • a sweetener composition comprising at least one preservative and a sweetener composition comprises aspartame, acesfulame potassium or other salts, and sucralose in combination with at least one sweet taste improving inorganic salt additive.
  • the at least one sweet taste improving inorganic salt additive is present in an amount in the range of about 25 to about 5,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination with magnesium chloride; at least one preservative and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination with magnesium sulfate; or at least one preservative and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination with magnesium sulfate and sodium chloride.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving organic acid salt additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at least one sweet taste improving organic acid salt additive
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with choline chloride in citrate buffer, D-gluconic acid sodium salt, guanidine HCl, D-glucosamine HCI, amiloridc HCI, or combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving organic acid additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at least one sweet taste improving organic acid additive
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fumaric acid, malic acid, tartaric acid, citric acid, adipic acid, ascorbic acid, tannic acid, succinic acid, glutaric acid, or combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin cyclamate
  • aspartame acesulfame potassium or other salts
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside FV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive is provided.
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine, L-alanine, L-serine, L- threonine, ⁇ -alanine, aminobutyric acid (alpha-, beta-, or gamma-isomers), L-aspartic acid, L- glutamic acid, L-lysine, glycine and L-alanine mixture, salt derivatives or combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving surfactant additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at least one sweet taste improving surfactant additive
  • Non- limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with dioctyl sulfosuccinate sodium, cetylpyridinium chloride, hexadecyltrimethylammonium bromide, sucrose olcatc, polysorbate 20, polysorbate 80, lecithin, or combinations thereof.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving polymer additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at least one sweet taste improving polymer additive
  • Non- limiting examples include at least one preservative and a s ⁇ veetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with cationic polymer such as polyethyleneimine, poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), polyornithine (e.g., poly-L- ⁇ -omithine or poly- ⁇ -ornithine), chitosan, or combinations thereof.
  • cationic polymer such as polyethyleneimine, poly-L-lysine (e.g., poly-L- ⁇ -lysine or poly-L- ⁇ -lysine), polyorn
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving polymer additive and at least one sweet taste improving polyol additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving polymer additive is present in an amount from about 30 to about 2,000 ppm of the composition, and the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with a hydrocolloid, such as a gum acacia seyal, and erythritol.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with a hydrocolloid
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving protein or protein hydrolysate additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at least one sweet taste improving protein or protein hydrolysate additive
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with bovine serum albumin (BSA), whey protein or combinations thereof.
  • REBA rebaudioside-A
  • BSA bovine serum albumin
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving inorganic acid salt additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition and the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 25 to about 5,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and alum; at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and potassium chloride; at least one preservative and a sweetener composition comprising rebaudio
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving inorganic acid salt additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition and the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 25 ppm to about 5,000 ppm.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose and alum; at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose and potassium chloride; at least one preservative and
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving bitter additive and at least one sweet taste improving inorganic salt additive is provided.
  • REBA rebaudioside-A
  • a non-limiting example include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with urea and sodium chloride.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with urea and sodium chloride.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, L ⁇ o Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other sails, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving polyamino acid additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition and the at least one sweet taste improving polyamino acid additive is present in an amount from about 30 to about 2,000 ppm of the composition.
  • Non-limiting examples include at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and poly- ⁇ -L-lysine; and at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and poIy- ⁇ -L- lysine.
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving organic acid additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition and the at least one sweet taste improving organic acid additive is present in an amount from about 25 to about 5,000 ppm of the composition.
  • a non-limiting example includes at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and sodium gluconate.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving carbohydrate additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition and the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition.
  • a non-limiting example includes at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV 5 mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with L-alanine and fructose.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV 5 mogroside V mogroside IV 5 mogroside V
  • Luo Han Guo sweetener monatin, curculin, sucralose, saccharin, cyclamate
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive, at least one sweet taste improving polyol additive, at least one sweet taste improving inorganic salt additive, and at least one sweet taste improving organic acid salt additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition
  • the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition
  • the at least one sweet taste improving inorganic salt additive is present in an amount from about 50 to about 5,000 ppm of the composition
  • the at least one sweet taste improving organic acid salt additive is present in an amount from about 20 to about 10,000 ppm of the composition.
  • a non-limiting example includes at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with erythritol, glycine, KCl, KH 2 PO4, and choline chloride.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with eryth
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V 1 Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive, at least one sweet taste improving carbohydrate additive, and at least one sweet taste improving polyol additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside V 1 Luo Han Guo sweetener
  • monatin curculin
  • sucralose sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with at
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition
  • the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition
  • the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition.
  • a non-limiting example includes at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with L-alanine, fructose, and erythritol.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin sucralose
  • saccharin saccharin
  • cyclamate aspartame
  • aspartame acesulfame potassium or other salts
  • neotame in combination with L-alanine, fructose, and
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive, at least one sweet taste improving polyol additive, and at least one sweet taste improving inorganic acid salt additive is provided.
  • REBA rebaudioside-A
  • the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition
  • the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition
  • the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 50 to about 5,000 ppm of the composition.
  • a non-limiting example includes at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with erythritol, glycine, KCI, and KH 2 PO 4 .
  • REBA rebaudioside-A
  • a sweetener composition comprising at least one preservative and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, glvcvrrihizin such as mono-ammonium glycyrrhizic acid salt hydrate, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with a sweet taste improving inorganic acid salt additive is provided.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V Luo Han Guo sweetener
  • monatin curculin
  • glvcvrrihizin such as mono-ammonium glycyrrhizic acid salt hydrate
  • a non-limiting example includes at least one preservative and a sweetener composition
  • a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, glycyrrihizin such as mono-ammonium glycyrrhizic acid salt hydrate, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with sodium chloride.
  • REBA rebaudioside-A
  • stevia stevioside
  • mogroside IV mogroside IV
  • mogroside V mogroside V
  • Luo Han Guo sweetener monatin
  • curculin glycyrrihizin
  • glycyrrihizin such as mono-ammonium glycyrr
  • the desired weight ratio of the natural and/or synthetic high-potency sweetener to sweet taste improving composition(s) in the sweetener composition will depend on the particular natural and/or synthetic high-potency sweetener, and the sweetness and other characteristics desired in the final product. Natural and/or synthetic high-potency sweeteners vary greatly in their potency, ranging from about 30 times more potent than sucrose to about 8,000 times more potent than sucrose on a weight basis.
  • the weight ratio of the natural and/or synthetic high-potency sweetener to sweet taste improving composition may for example range from range between 10,000:1 and 1 :10,000; a further non-limiting example may range from about 9,000: 1 to about 1 :9,000; yet another example may range from about 8,000: 1 to about 1 :8,000; a further example may range from about 7,000:1 to about 1 :7,000; another example may range from about 6,000: 1 to about 1 :6000; in yet another example may range from about 5,000: 1 to about 1 :5,000; in yet another example may range from about 4,000: 1 to about 1 :4,000; in yet another example may range from about 3,000: 1 to about 1 :3,000; in yet another example may range from about 2,000:1 to about 1 :2,000; in yet another example may range from about 1,500: 1 to about 1 : 1 ,500; in yet another example may range from about 1,000:1 to about 1 : 1,000; in yet another example may range from about 900:1 to about 1 :900; in yet another
  • the combination of at least one natural and/or synthetic high-potency sweetener to at least one sweet taste improving composition may be carried out in any pH range that does not materially or adversely affect the taste of the sweetener composition.
  • a non-limiting example of the pH range may be from about 2 to about 8.
  • ⁇ farther example includes a pH range from about 2 to about 5.
  • One of ordinary skill in the art may combine at least one natural and/or synthetic high-potency sweetener, at least one sweet taste improving composition, and sweetenble composition in any manner.
  • at least one natural and/or synthetic high-potency sweetener may be added to the sweetenble composition before the at least one sweet taste improving composition.
  • at least one natural and/or synthetic high-potency sweetener may be added to the sweetenble composition after the at least one sweet taste improving composition.
  • at least one natural and/or synthetic high-potency sweetener may be added to the sweetenble composition simultaneously with the at least one sweet taste improving composition.
  • At least one natural and/or synthetic high-potency sweetener may be combined with the at least one sweet taste improving composition prior to being added to a sweetenble composition.
  • the at least one natural and/or synthetic high-potency sweetener may be in a pure, diluted, or concentrated form as a liquid (e.g., solut ion), solid (e.g., powder, chunk, pellet, grain, block, crystalline, or the like), suspension, gas state, or combinations thereof may be contacted with the at least one sweet taste improving composition which may be in a pure, diluted, or concentrated form as a liquid (e.g., solut ion), solid (e.g., powder, chunk, pellet, grain, block, crystalline, or the like), suspension, gas state, or combinations thereof before both are contacted with a sweetenble composition.
  • each component of the sweetenable composition may be added simultaneously, in an alternating pattern, in a random pattern, or any other pattern.
  • the amount of natural and/or synthetic high-potency sweetener present in a sweetened composition varies widely depending on the desired sweetness. Those of ordinary skill in the art can readily discern the appropriate amount of sweetener to put in the sweetened composition.
  • the at least one natural and/or synthetic high-potency sweetener is present in the sweetened composition in an amount in the range of about 1 to about 5,000 ppm of the sweetened composition and the at least one sweet taste improving composition is present in the sweetened composition in an amount in the range of about 0.1 to about 100,000 ppm of the sweetened composition.
  • suitable amounts of natural high- potency sweeteners for sweetened compositions comprise amounts in the range from about 100 ppm to about 3,000 ppm for rebaudioside A; from about 50 ppm to about 3,000 ppm for stevia; from about 50 ppm to about 3,000 ppm for stevioside; from about 50 ppm to about 3,000 ppm for mogroside IV; from about 50 ppm to about 3,000 ppm for mogroside V; from about 50 ppm to about 3,000 ppm for Luo Han Guo sweetener; from about 5 ppm to about 300 ppm for monatin, from about 5 ppm to about 200 ppm thaumatin; and from about 50 ppm to about 3,000 ppm for mono-ammonium glycyrrhizic acid salt hydrate.
  • suitable amounts of synthetic high-potency sweeteners for sweetened compositions comprise a range from about 1 ppm to about 60 ppm for alitame; from about 10 ppm to about 600 ppm for aspartame; from about 1 ppm to about 20 ppm for neotame; from about 10 ppm to about 500 ppm for acesulfame potassium; from about 50 ppm to about 5,000 ppm for cyclamate; from about 10 ppm to about 500 ppm for saccharin; from about 5 ppm to about 250 ppm for sucralose; from about 1 ppm to about 20 ppm for N-[N-[3-(3-hydroxy-4-methoxyphenyl)pro ⁇ yl]-L- ⁇ -aspartyl]-L- phenylalanine 1-methyl ester; from about 1 ppm to about 20 ppm for N-[N-[3-(3-hydroxy-4- methoxyphenyl)pro ⁇ yl]
  • a sweetened dried apricot composition is prepared with 100 ppm sulfur dioxide, 20 mg rebaudioside A, and 1.75 g erythritoi per 40 g serving of dried apricots.
  • a sweetened cured ham composition is prepared with 100 mg sodium nitrate,
  • Example A3 Sweetened Cola Beverage Composition
  • a sweetened diet cola beverage composition is prepared with 100 ppm sodium benzoate, 400 ppm rebaudioside A, and 3.5 % erythritoi per 240 mL serving of cola beverage.
  • Crude rebaudioside A (77.4% purity) mixture was obtained from a commercial source.
  • the impurities (6.2% stevioside, 5.6% rebaudioside C, 0.6 % rebauiodioside F, 1.0 % other steviolglycostdes, 3.0% rebaudioside D, 4.9% rebaudioside B, 0.3% steviolbioside) were identified and quantified using HPLC on dry basis, moisture content 4.7%.
  • Crude rebaudioside A (80.37 %) was obtained from a commercial source.
  • the impurities (6.22% stevioside, 2.28% rebaudioside C, 0.35% Dulcoside, 0.78 % rebaudioside
  • Crude rebaudioside A (80.37%) was obtained from a commercial source.
  • the impurities (6.22% stevioside, 2.28% rebaudioside C, 0.35% Dulcoside, 0.78 % rebaudioside F, 0.72 % other steviolglycosides, 3.33% rebaudioside B, 0.07% steviolbioside) were identified by HPLC on dry basis, moisture content 3.4%.
  • Crude rebaudioside A 50 g), ethanol (95%, 160 mL), methanol (99%, 60 mL) and water (25 mL) were combined and heated to approximately 30 0 C for 10 minutes. The clear solution was cooled to 22 0 C for 16 hours.
  • a mixture of crude rebaudioside A (41 % purity, 50 g), ethanol (95%, 160 mL), methanol (99.8 %, 60 mL) and water (25 mL) were combined by stirring at 22 0 C.
  • a white product crystallized out in 5-20 hours.
  • the mixture was stirred for additional 48 hours.
  • the white crystalline product was filtered and washed twice with ethanol (95%, 25 mL).
  • the wet cake of white crystalline product then was slurried in methanol (99.8 %, 200 mL) for 16 hours, filtered, washed twice with methanol (99.8 %, 25 mL), and dried in a vacuum oven at 60°C for 16-24 hours under reduced pressure (20 mm) to give 12.7 g of purified product (>97% by HPLC).
  • the wet cake of white crystalline product was slurried in methanol (99.8 %, 350 mL) for 16 hours, filtered, washed twice with methanol (99.8 %, 25 mL) and dried in a vacuum oven at 60 0 C for 16-24 hours under reduced pressure (20 mm) to give 22.2 g of purified product (>97% by HPLC).
  • a solution of rebaudioside A ( >97% pure by HPLC ) was prepared in double distilled water (12.5 gm in 50 mL, 25 % concentration) by stirring the mixture at 40 0 C for 5 minutes.
  • An amorphous form of rebaudioside A was formed by immediately using the clear solution for spray drying with the Lab-Plant spray drier SD-04 instrument (Lab-Plant Ltd., West Yorkshire, U.K.). The solution was fed through the feed pump into the nozzle atomizer which atomized it into a spray of droplets with the help of a constant flow of nitrogen / air.
  • This dry powder (11-12 g, H 2 O 6.74 %) was discharged continuously from the drying chamber and was collected in a bottle.
  • the solubility in water at room temperature was determined to be > 35.0 %.
  • Example Set G Sensory evaluation of the samples prepared in Example Set G was carried out under the following protocol, similar to that described hereinabove. In this test protocol, none of the samples were swallowed. All samples were expectorated and the mouth was rinsed with water after the tasting. Immediately upon sensing maximal sweetness, the sample was expectorated, the mouth was rinsed with water and the rate of sweetness decay ("Sweetness Linger") was measured, where attention was focused on the sweetness 3-4 min after the water rinse. After sample tasting was complete, a salty oyster cracker was chewed followed by a water rinse, and at least 5 minutes followed before tasting the next sample.
  • Sweetness Linger rate of sweetness decay
  • the "Sweetness Linger" rating for sucrose observed by this protocol is defined as 0.
  • the Sweetness Linger of a 500 ppm of REBA control sample is defined as 5.
  • REBA is a natural non-caloric sweetener with a very clean flavor profile (i.e., only sweet) and an acceptable sweetness onset rate but with a sweetness which lingers quite noticeably more than that of carbohydrate sweeteners.

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010025001A1 (en) * 2008-08-29 2010-03-04 Tropicana Products, Inc. Naturally sweetened juice beverage products
WO2011024471A1 (ja) * 2009-08-27 2011-03-03 小川香料株式会社 高甘味度甘味料の呈味改善剤
CN102146106A (zh) * 2010-02-10 2011-08-10 山东圣旺药业股份有限公司 一种95%含量莱鲍迪苷a的提取方法
US11524268B2 (en) 2016-11-09 2022-12-13 Pepsico, Inc. Carbonated beverage makers, methods, and systems

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8334006B2 (en) 2005-10-11 2012-12-18 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8337927B2 (en) * 2005-10-11 2012-12-25 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8790730B2 (en) 2005-10-11 2014-07-29 Purecircle Usa Process for manufacturing a sweetener and use thereof
US8257948B1 (en) 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US9392799B2 (en) 2011-02-17 2016-07-19 Purecircle Sdn Bhd Glucosyl stevia composition
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
BRPI0715752A2 (pt) * 2006-08-11 2013-10-15 Ajinomoto Co., Inc. bebida carbonatada contendo adoÇante de alta intensidade melhorada no sabor, e, mÉtodos de produzir a mesma, e de melhorar o sabor de uma bebida carbonatada contendo adoÇante de alta intensidade
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
US9877500B2 (en) * 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
US8029846B2 (en) * 2007-03-14 2011-10-04 The Concentrate Manufacturing Company Of Ireland Beverage products
US20080226802A1 (en) * 2007-03-14 2008-09-18 Concentrate Manufacturing Company Of Ireland Beverage having natural sweeteners with one or more stevia components and source of berry
US20080226788A1 (en) * 2007-03-14 2008-09-18 Concentrate Manufacturing Company Of Ireland Lhg compositions for reducing lingering bitter taste of steviol glycosides
US20080226803A1 (en) * 2007-03-14 2008-09-18 Concentrate Manufacturing Company Of Ireland Natural flavoring agent for sugar-sweetened tea beverage to taste like high fructose corn syrup-sweetened beverage
US8277862B2 (en) 2007-03-14 2012-10-02 Concentrate Manufacturing Company Of Ireland Beverage products having steviol glycosides and at least one acid
US8277861B2 (en) 2007-03-14 2012-10-02 Concentrate Manufacturing Company Of Ireland Beverage products having steviol glycosides and at least one acid
US8609069B2 (en) * 2009-05-18 2013-12-17 Redpoint Bio Corporation Rebaudioside C and its stereoisomers as natural product sweetness enhancers
US20110224311A1 (en) * 2009-07-17 2011-09-15 Palmer R Kyle Natural Product Sweetness Enhancers
US10758582B2 (en) 2009-08-17 2020-09-01 Xten Capital Group, Inc. Vaporized medicants and methods of use
US10918684B2 (en) 2009-08-17 2021-02-16 Cqens Technologies, Inc. Vaporized medicants and methods of use
US9254002B2 (en) * 2009-08-17 2016-02-09 Chong Corporation Tobacco solution for vaporized inhalation
US10098918B2 (en) 2009-08-17 2018-10-16 Chong Corporation Vaporized medicants and methods of use
US9770408B2 (en) 2009-08-17 2017-09-26 Chong Corporation Vaporized medicants and methods of use
US8524785B2 (en) * 2009-09-04 2013-09-03 International Flavors And Fragrances Inc. Methods for using rebaudioside C as a flavor enhancer
US8293299B2 (en) 2009-09-11 2012-10-23 Kraft Foods Global Brands Llc Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable Concentrated liquids
US20110070337A1 (en) * 2009-09-21 2011-03-24 Whitewave Services, Inc. Reduced Calorie Soy Beverage
US8568818B2 (en) * 2009-10-15 2013-10-29 Pure Circle Sdn Bhd High-purity Rebaudioside D and low-calorie carbonated drink containing the same
US8574656B2 (en) * 2009-10-15 2013-11-05 Purecircle Sdn Bhd High-purity Rebaudioside D and low-calorie fruit juice containing the same
US10888099B2 (en) 2009-11-12 2021-01-12 Purecircle Sdn Bhd. Granulation of a Stevia sweetener
MX353094B (es) 2009-11-12 2017-12-19 Purecircle Usa Inc Granulacion de un edulcorante de stevia.
RU2500301C1 (ru) * 2009-12-18 2013-12-10 Стукли-Ван Кэмп, Инк. Белковый восстанавливающий напиток
US20110189360A1 (en) * 2010-02-04 2011-08-04 Pepsico, Inc. Method to Increase Solubility Limit of Rebaudioside D in an Aqueous Solution
JP4848463B2 (ja) * 2010-03-05 2011-12-28 株式会社 伊藤園 カルシウム含有無果汁炭酸飲料
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
US10696706B2 (en) 2010-03-12 2020-06-30 Purecircle Usa Inc. Methods of preparing steviol glycosides and uses of the same
EP2544538B1 (en) 2010-03-12 2022-06-15 PureCircle USA Inc. High-purity steviol glycosides
CN101791005A (zh) * 2010-04-12 2010-08-04 陕西科技大学 一种延长魔芋豆腐保质期的方法
US20120021111A1 (en) * 2010-07-23 2012-01-26 Aexelon Therapeutics, Inc. Natural Low Caloric Sweetener Compositions for Use in Beverages, Foods and Pharmaceuticals, and Their Methods of Manufacture
US9101162B2 (en) * 2010-09-03 2015-08-11 Purecircle Sdn Bhd High-purity mogrosides and process for their purification
JP5859191B2 (ja) 2010-09-29 2016-02-10 松谷化学工業株式会社 高甘味度甘味料に対する呈味改良組成物およびその応用
CN102450624B (zh) * 2010-10-28 2015-04-01 纽威(武汉)生物科技有限公司 复合型天然无糖甜味剂
US9029426B2 (en) 2010-12-13 2015-05-12 Purecircle Sdn Bhd Highly soluble Rebaudioside D
US9510611B2 (en) 2010-12-13 2016-12-06 Purecircle Sdn Bhd Stevia composition to improve sweetness and flavor profile
CN102150775B (zh) * 2011-01-07 2012-12-19 陈显刚 一种甜味剂及其制备方法
MX362676B (es) 2011-02-10 2019-01-31 Purecircle Usa Composición de estevia.
US9603373B2 (en) 2011-02-17 2017-03-28 Purecircle Sdn Bhd Glucosyl stevia composition
US11690391B2 (en) 2011-02-17 2023-07-04 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US9474296B2 (en) 2011-02-17 2016-10-25 Purecircle Sdn Bhd Glucosyl stevia composition
US9894922B2 (en) 2011-05-18 2018-02-20 Purecircle Sdn Bhd Glucosyl rebaudioside C
PL2713763T3 (pl) 2011-05-31 2019-10-31 Purecircle Usa Inc Kompozycja stewiowa
ES2579827T3 (es) 2011-06-03 2016-08-17 Purecircle Usa Composición de estevia
BR122019003378B1 (pt) 2011-06-20 2020-07-28 Purecircle Usa Inc composição ingerível doce, produto alimentício ou de bebida, preparado de droga, farmacêutico ou cosmético, edulcorante e produto compreendendo a composição ingerível doce
US9771434B2 (en) 2011-06-23 2017-09-26 Purecircle Sdn Bhd Products from stevia rebaudiana
US10480019B2 (en) 2011-08-10 2019-11-19 Purecircle Sdn Bhd Process for producing high-purity rubusoside
US20140171520A1 (en) 2011-09-07 2014-06-19 Avetik Markosyan Highly soluble stevia sweetener
WO2013036768A1 (en) * 2011-09-09 2013-03-14 The Coca-Cola Company Improved sweetener blend compositions
ES2524151T3 (es) 2011-11-18 2014-12-04 International Flavors & Fragrances, Inc. Método para purificar rebaudiósido C
US20130136839A1 (en) * 2011-11-28 2013-05-30 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Taste-Masking Compositions, Sweetener Compositions and Consumable Product Compositions Containing the Same
CA3085086C (en) 2011-12-06 2023-08-08 Delta Faucet Company Ozone distribution in a faucet
EP4124245A1 (en) 2011-12-19 2023-02-01 The Coca-Cola Company Beverage comprising rebaudioside x
US20150004298A1 (en) * 2011-12-20 2015-01-01 Cargill, Incorporated Low level blend of monatin and rebaudioside a
US8877259B2 (en) 2012-02-09 2014-11-04 Mary Kay Inc. Cosmetic formulation
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
MX395285B (es) 2012-05-22 2025-03-25 Purecircle Sdn Bhd Glucosidos de esteviol de alta pureza.
US11013248B2 (en) 2012-05-25 2021-05-25 Kraft Foods Group Brands Llc Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings
CA2875401A1 (en) 2012-06-27 2014-01-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Taste-masking compositions, sweetener compositions and consumable product compositions containing the same
PL2934183T3 (pl) * 2012-12-20 2019-01-31 Cargill, Incorporated Kompozycja zawierająca glikozyd stewiolowy i maltozę
CN103242187B (zh) * 2013-04-28 2016-01-06 华南理工大学 抗菌防腐剂山梨酸氨基酸酯衍生物及其制备方法
US10952458B2 (en) 2013-06-07 2021-03-23 Purecircle Usa Inc Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
EP3714699B1 (en) 2013-06-07 2024-12-18 PureCircle USA Inc. Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
CN103284323B (zh) * 2013-06-19 2014-12-10 江苏中烟工业有限责任公司徐州卷烟厂 一种卷烟用烟草甜味剂及其使用方法
AU2014298430A1 (en) * 2013-07-31 2016-02-11 Dsm Ip Assets B.V. Steviol glycosides
WO2015023928A1 (en) * 2013-08-15 2015-02-19 Cargill, Incorporated Sweetener and sweetened compositions incorporating rebaudoside n
CN103653181B (zh) * 2013-12-05 2015-09-30 南通双和食品有限公司 一种肉类防腐抗氧剂
US10357052B2 (en) * 2014-06-16 2019-07-23 Sweet Green Fields USA LLC Rebaudioside A and stevioside with improved solubilities
US11202461B2 (en) 2014-09-02 2021-12-21 Purecircle Sdn Bhd Stevia extracts
CN104725444A (zh) * 2015-03-24 2015-06-24 杨健 高效能制备高纯度莱鲍迪甙a的方法
CN104711159A (zh) * 2015-04-02 2015-06-17 安靖东 一种用于鲜啤酒保鲜的自分解型冷杀菌技术
CA2985669C (en) 2015-05-20 2022-05-03 Cargill, Incorporated Glycoside compositions
US11647771B2 (en) 2015-10-26 2023-05-16 Purecircle Usa Inc. Steviol glycoside compositions
RU2764635C2 (ru) 2015-12-15 2022-01-19 ПЬЮРСЁРКЛ ЮЭсЭй ИНК. Композиция стевиол гликозида
CN108463437B (zh) 2015-12-21 2022-07-08 德尔塔阀门公司 包括消毒装置的流体输送系统
CN105725092A (zh) * 2016-02-26 2016-07-06 江凯 改善肉制品品质的组合物
SG11201906916PA (en) * 2017-01-31 2019-08-27 Suntory Holdings Ltd Non-alcoholic beer taste beverage packed in container
US11091597B2 (en) * 2017-05-23 2021-08-17 The Research Foundation For The State University Of New York Packaging material and methods of using the same
EP3691468A4 (en) 2017-10-06 2021-10-20 Cargill, Incorporated EASILY SOLUBLE STEVIOL GLYCOSIDE COMPOSITIONS
US10602758B2 (en) * 2018-04-16 2020-03-31 Almendra Pte. Ltd Methods and compositions for improved taste quality
CN109043468A (zh) * 2018-07-16 2018-12-21 南通市常海食品添加剂有限公司 一种高液态三氯蔗糖组合物及其制备方法
CN109730136A (zh) * 2019-02-26 2019-05-10 湖州周生记餐饮管理有限公司 一种卤肉熟食的储存方法
WO2020203655A1 (ja) * 2019-03-29 2020-10-08 サントリーホールディングス株式会社 カテキン類含有飲料、その製造方法及びカテキン類含有飲料の苦味を低減する方法
WO2020210118A1 (en) 2019-04-06 2020-10-15 Cargill, Incorporated Sensory modifiers
US20230077392A1 (en) * 2019-12-27 2023-03-16 Suntory Holdings Limited Oral composition with increased sweetness
JP2022093166A (ja) * 2020-12-11 2022-06-23 三栄源エフ・エフ・アイ株式会社 ミネラル用風味マスキング剤及びその使用
CN113892627B (zh) * 2021-09-28 2023-11-17 深圳市真味生物科技有限公司 一种多级复配甜味剂及其制备工艺
JP2024012919A (ja) 2022-07-19 2024-01-31 サントリーホールディングス株式会社 ステビオール配糖体およびアルコールを含む飲料
JP2024053439A (ja) 2022-10-03 2024-04-15 サントリーホールディングス株式会社 ステビオール配糖体を含む飲料の製造方法および飲料
CN116076694B (zh) * 2022-10-12 2024-06-28 四川盈嘉合生科技有限公司 一种甜菊糖苷甜味剂及其制备方法
CN116898876B (zh) * 2023-07-13 2025-07-04 浙江同伍生物医药有限公司 一种葡萄糖酸钙锌口服溶液组合物及其检测方法
CN117106000A (zh) * 2023-07-17 2023-11-24 华南理工大学 一种甜菊糖苷聚集体及其制备方法和应用

Family Cites Families (188)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3656973A (en) * 1968-07-18 1972-04-18 Allied Chem Non-nutritive functional sugar substitute
US3717477A (en) * 1970-01-16 1973-02-20 Ajinomoto Kk Sweetening agent containing tryptophane and saccharin
US3725453A (en) * 1970-10-16 1973-04-03 American Home Prod L-4{40 -cyano-3-(2,2,2-trihaloacetamido) succinanilic acids
JPS51142570A (en) * 1975-06-04 1976-12-08 Morita Kagaku Kogyo Method of imparting sweetness to food or pharmaceutical agent
US4256641A (en) * 1976-06-22 1981-03-17 Hoffmann-La Roche Inc. Novel syntheses of tryptophans
JPS53148575A (en) 1977-06-01 1978-12-25 Sanei Kagaku Kogyo Kk Stevia sweetening agent
JPS5550866A (en) 1978-10-06 1980-04-14 Maruzen Kasei Kk Propylene glycol composition for food additive
US4316847A (en) * 1979-07-30 1982-02-23 Hoffmann-La Roche Inc. Pyrroles and pyrrolidines
JPS5655174A (en) 1979-10-12 1981-05-15 Ougontou:Kk Method for improving taste of natural sweetening agent
US4797298A (en) * 1980-01-21 1989-01-10 Pfizer, Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4804782A (en) * 1980-01-21 1989-02-14 Pfizer, Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4894464A (en) * 1980-01-21 1990-01-16 Pfizer Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4528204A (en) 1981-08-27 1985-07-09 Dynagel, Incorporated Preparation of hydrolyzed collagen-containing products from non-gelled liquid hydrolyzed collagen concentrate and gelled products prepared therefrom
US4492755A (en) * 1982-06-30 1985-01-08 Nabisco Brands, Inc. Process for isomerizing L-mannose to L-fructose
US4440855A (en) * 1982-06-30 1984-04-03 Nabisco Brands, Inc. Process for preparing L-glucosone
CA1206370A (en) * 1982-08-17 1986-06-24 Ajinomoto Co., Inc. Stabilized aspartame compositions
JPS59183670A (ja) 1983-04-04 1984-10-18 Maruzen Kasei Kk 低カロリ−甘味料
JPS6075252A (ja) 1983-09-30 1985-04-27 Sekisui Chem Co Ltd 低カロリ−甘味料組成物
US4612942A (en) 1984-03-08 1986-09-23 Stevia Company, Inc. Flavor enhancing and modifying materials
JPS60188035A (ja) 1984-03-08 1985-09-25 Riken Vitamin Co Ltd ステビオサイドの呈味改善法
US4738854A (en) * 1984-12-04 1988-04-19 Nabisco Brands, Inc. Comestible containing moisture and shelf storage stabilized L-aspartic acid derivative
US4638071A (en) * 1984-12-27 1987-01-20 General Foods Corporation Cycloalkyl ethers and thioethers of dipeptides
US4652457A (en) * 1985-05-06 1987-03-24 General Foods Corporation L-aminodicarboxylic acid aminoalkenoic acid ester amides
US4654439A (en) * 1985-05-24 1987-03-31 General Foods Corporation L-aminodicarboxylic acid amides of alkoxyalkylamines
JPS6279752A (ja) 1985-10-03 1987-04-13 Dainippon Ink & Chem Inc ステビア甘味料及びその製造法
JPH0679547B2 (ja) 1985-10-16 1994-10-12 大日本インキ化学工業株式会社 ステビア甘味料及びその製造方法
US4814172A (en) * 1985-10-31 1989-03-21 Product Resources International, Inc. Liquid bran drink
US4731246A (en) * 1985-10-31 1988-03-15 Product Resources International, Inc. Liquid bran drink
US4737375A (en) * 1985-12-26 1988-04-12 The Procter & Gamble Company Beverages and beverage concentrates nutritionally supplemented with calcium
US5087460A (en) * 1986-12-10 1992-02-11 Warner-Lambert Company Reduced-calorie confectionery coated chewing gum compositions and methods for preparing same
JPH07100013B2 (ja) 1987-04-14 1995-11-01 三菱化学株式会社 味覚調整剤
US5387431A (en) * 1991-10-25 1995-02-07 Fuisz Technologies Ltd. Saccharide-based matrix
JPS63304964A (ja) 1987-06-04 1988-12-13 Ajinomoto Co Inc 甘味組成物
US5739409A (en) * 1987-06-19 1998-04-14 The Regents Of The University Of California Endogenously sweetened transgenic plant products
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
US4948609A (en) 1988-02-12 1990-08-14 Nabisco Brands, Inc. Fruit and vegetable dried food product
ES2065479T3 (es) 1989-03-08 1995-02-16 Pfizer Prevencion del mal sabor en ciertas bebidas edulcoradas con alitame.
JP3084530B2 (ja) 1989-03-30 2000-09-04 東和化成工業株式会社 脂肪代替物としてのマルチトールを含有する低脂肪食品の製造方法
US5080910A (en) * 1990-05-15 1992-01-14 Werner-Lambert Company Stabilized chlorodeoxysugar sweetening agents in powder form and methods for preparing same
JPH0491753A (ja) 1990-08-02 1992-03-25 Makise Sangyo Kk 液状甘味組成物
JPH04148659A (ja) 1990-10-09 1992-05-21 Dainippon Ink & Chem Inc 甘味料及び甘味食品
NZ240818A (en) 1990-12-14 1993-08-26 Mcneil Ppc Inc Liquid sucralose concentrate compositions containing preservative, buffer and liquid
US5108763A (en) * 1991-04-03 1992-04-28 Warner-Lambert Company Microencapsulated high intensity sweetening agents having prolonged sweetness release and methods for preparing same
US5484593A (en) * 1991-05-28 1996-01-16 Iwasaki; Kazuo Diet composition comprising gymnema inodrum and a method for suppressing the absorption of saccharides
DE69331839T2 (de) * 1992-01-29 2002-12-12 Takeda Chemical Industries, Ltd. Schnellösliche Tablette und ihre Herstellung
JP2654529B2 (ja) * 1992-03-27 1997-09-17 大塚製薬株式会社 健康飲料組成物
JPH05316960A (ja) * 1992-05-21 1993-12-03 Takasago Internatl Corp 飲食品の香味を改善する方法
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
US5298272A (en) * 1992-12-02 1994-03-29 The Regents Of The University Of California Bridged carboxylic ortho ester sweetener
JPH06192283A (ja) 1992-12-17 1994-07-12 Ikeda Pan:Kk 純粋なレバウディオサイドａを生産する方法
US5527555A (en) * 1993-02-16 1996-06-18 Wisconsin Alumni Research Foundation Brazzein sweetener
US5433965A (en) 1993-02-16 1995-07-18 The Procter & Gamble Company Beverage compositions and sweetening compositions which contain juice derived from botanical subfamily Cucurbitaceae
BE1007425A3 (nl) * 1993-08-30 1995-06-13 Holland Sweetener Co Werkwijze en inrichting voor de terugwinning van grondstoffen in het aspartaambereidingsproces.
JP3436317B2 (ja) 1993-11-24 2003-08-11 大日本インキ化学工業株式会社 ステビア甘味料の製造方法
US5498702A (en) * 1993-12-16 1996-03-12 California Natural Products Treated pectinic acid process and product
US5472722A (en) 1993-12-21 1995-12-05 Burgers' Ozark Country Cured Hams, Inc. Low salt curing process for preparing dry cured country ham
JPH08214A (ja) 1994-06-17 1996-01-09 Ikeda Pan:Kk レバウディオサイドａ系甘味料およびその製造方法
JP2783764B2 (ja) 1994-09-27 1998-08-06 三栄源エフ・エフ・アイ株式会社 低カロリー甘味製剤及びその製造方法
US5576039A (en) 1995-02-03 1996-11-19 Bush Boake Allen Inc. Colored jelly-type substance, method of preparation, and composition containing same
EP0751146B1 (en) * 1995-06-30 2002-03-13 Holland Sweetener Company V.o.F. Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester from aqueous solution
JP4051717B2 (ja) 1995-08-04 2008-02-27 大正製薬株式会社 ビオチン含有内服液剤
JP4726269B2 (ja) 1995-11-16 2011-07-20 大正製薬株式会社 内服液剤
JP3046763B2 (ja) 1995-12-26 2000-05-29 サラヤ株式会社 不正六面体低カロリー甘味料およびその製造方法
GB9604334D0 (en) 1996-02-29 1996-05-01 Cerestar Holding Bv Use of erythritol in soft drinks
US6822070B2 (en) * 1996-03-11 2004-11-23 David Baltimore Truncated CRAF1 inhibits CD40 signaling
WO1998004156A1 (en) 1996-07-26 1998-02-05 Bateman Kristine A Dietetic one-to-one sugar substitute composition for table top, baking and cooking applications
US5731025A (en) 1996-09-11 1998-03-24 Mitchell; David C. Method and composition for inhibiting decomposition of aspartame
US5962678A (en) * 1996-09-13 1999-10-05 Alberta Research Council Method of extracting selected sweet glycosides from the Stevia rebaudiana plant
JP3498502B2 (ja) 1996-11-06 2004-02-16 三菱化学株式会社 密封容器入り炭酸飲料
JP3498505B2 (ja) 1996-11-21 2004-02-16 三菱化学株式会社 酸性飲料
NZ336326A (en) * 1996-12-20 2001-02-23 Nutrinova Gmbh Method for increasing the sweetening power and enhancing the taste of a mixture of extremely powerful sweetening agents
JPH10271928A (ja) * 1997-01-30 1998-10-13 Morita Kagaku Kogyo Kk ステビア・レバウディアナ・ベルトニーに属する新植物
JPH10276712A (ja) 1997-04-08 1998-10-20 Nikken Kasei Kk 甘味組成物の製造方法
JP3588971B2 (ja) 1997-05-08 2004-11-17 三菱化学株式会社 低カロリー調製ココア
JP4034862B2 (ja) * 1997-06-02 2008-01-16 株式会社林原生物化学研究所 スクロースの後味改善方法とその用途
JP3505367B2 (ja) 1997-09-10 2004-03-08 三菱化学フーズ株式会社 甘味料組成物
JP3562785B2 (ja) 1997-10-21 2004-09-08 三菱化学フーズ株式会社 低カロリー酸性蛋白飲料およびその製造方法
US6682766B2 (en) * 1997-12-01 2004-01-27 The Procter & Gamble Company Beverage comprising an effective amount of flavanols as sweetness cutting composition
JPH11243906A (ja) 1998-03-05 1999-09-14 Morita Kagaku Kogyo Kk 甘味料
JP3763075B2 (ja) * 1998-04-24 2006-04-05 サンスター株式会社 歯周病の予防又は治療用の食品組成物、口腔用組成物及び医薬組成物
US6855360B2 (en) * 1998-05-18 2005-02-15 Kohjin Co., Ltd. Sweetness improving agent and foods containing the same
FR2778822B1 (fr) 1998-05-25 2000-08-04 Roquette Freres Composition edulcorante et ses utilisations
JPH11346708A (ja) 1998-06-04 1999-12-21 Nikken Chem Co Ltd エリスリトール含有液状甘味料組成物
AU4693999A (en) * 1998-06-18 2000-01-05 Kellogg Company An edible composition containing agglomerated fortificant particles and method of making and an edible agglomerated granule
TR200100345T2 (tr) * 1998-07-07 2001-08-21 Mcneil Specialty Products Company, Division Of Mcneil- Sükraloza tat vermenin geliştirilmesine ilişkin metod
US7186431B1 (en) 1998-08-27 2007-03-06 Barnard Stewart Silver Sweetening compositions and foodstuffs comprised thereof
US6214402B1 (en) * 1998-09-17 2001-04-10 The Nutrasweet Company Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l αaspartyl]-l-phenylalanine 1-methyl ester
NL1010135C2 (nl) 1998-09-21 2000-03-22 Sara Lee De Nv Zoetstoftablet.
US8236352B2 (en) * 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US6245373B1 (en) 1998-11-06 2001-06-12 Nutrinova, Inc. Acidified fruit and iced tea beverages incorporating high intensity sweetener blends
US20030008046A1 (en) * 1998-12-18 2003-01-09 Paula A. Gerlat Use of n-neohexyl-a-aspartyl-l-phenylalanine methyl ester as a flavor modifier
JP2000236842A (ja) 1998-12-24 2000-09-05 Nippon Paper Industries Co Ltd ステビア甘味料
US6048999A (en) * 1999-01-25 2000-04-11 The Nutrasweet Company N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester synergistic sweetener blends
US6180157B1 (en) * 1999-02-18 2001-01-30 The Nutrasweet Company Process for preparing an N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester agglomerate
JP3436706B2 (ja) 1999-03-26 2003-08-18 雪印乳業株式会社 高甘味度甘味料の苦味低減又は除去剤
WO2000057725A1 (en) * 1999-03-26 2000-10-05 The Nutrasweet Company PARTICLES OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
US6773716B2 (en) * 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
WO2000069283A1 (en) * 1999-05-13 2000-11-23 The Nutrasweet Company USE OF ADDITIVES TO MODIFY THE TASTE CHARACTERISTICS OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER
US20030161879A1 (en) 1999-06-29 2003-08-28 Shinji Ohmori Tablets quickly disintegrating in mouth
CA2278083A1 (en) 1999-07-20 2001-01-20 James Kenneth Laidler Method of extracting selected sweet glycosides from the stevia rebaudiana plant
NL1012701C2 (nl) 1999-07-26 2001-01-29 Sara Lee De Nv Zoetstof.
US6506434B1 (en) * 1999-08-06 2003-01-14 The Nutrasweet Company Process for coating N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester onto a carrier
AU7322100A (en) * 1999-10-04 2001-05-10 Ajinomoto Co., Inc. Sweetener compositions with high degree of sweetness having improved sweetness, corrigents and utilization thereof
KR20020034209A (ko) * 1999-10-05 2002-05-08 에가시라 구니오 고형상 감미료 조성물, 액상 감미료 조성물 및 이들의 사용
US20050042271A1 (en) * 1999-11-19 2005-02-24 Xel Herbaceuticals, Inc . Transdermal delivery system for alkaloids of aconitum species
JP4184558B2 (ja) 1999-12-03 2008-11-19 守田化学工業株式会社 甘味料組成物
US6783789B2 (en) * 1999-12-10 2004-08-31 Pepsico, Inc. Use of metal salts to improve the taste of low-calorie beverages sweetened with sucralose
DE19961338A1 (de) 1999-12-17 2001-06-21 Nutrinova Gmbh Feste Mischung von Lebensmittelinhalts- und Lebensmittelzusatzstoffen, Verfahren zu ihrer Herstellung und Verwendung derselben
US20020001651A1 (en) * 2000-01-24 2002-01-03 Norris Leslie Marie Method of altering and improving taste characteristics of edible consumables with monomeric or oligomeric polyphenolic compounds
JP2003521528A (ja) * 2000-02-01 2003-07-15 ステヴィア，エイプス 食事補強剤、又は非インシュリン依存性糖尿病、高血圧及び／又は代謝症候群の治療のための薬剤の調製に使用する物質
US20020004092A1 (en) 2000-02-02 2002-01-10 Riha William E. Low calorie beverages containing high intensity sweeteners and arabinogalactan
EP1125507A1 (en) * 2000-02-15 2001-08-22 Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.) Inulin products with improved nutritional properties
WO2001060842A2 (en) * 2000-02-16 2001-08-23 The Nutrasweet Company PROCESS FOR MAKING GRANULATED N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
US7115297B2 (en) * 2000-02-22 2006-10-03 Suzanne Jaffe Stillman Nutritionally fortified liquid composition with added value delivery systems/elements/additives
RU2251405C2 (ru) 2000-03-27 2005-05-10 Шотт Глас Композиции для косметических препаратов, средств личной гигиены, компонентов очищающего действия, пищевых добавок, способы их получения и применения
US20020150662A1 (en) * 2000-04-19 2002-10-17 Dewis Mark Lawrence Ethyl 3-mercaptobutyrate as a flavoring or fragrance agent and methods for preparing and using same
US6534107B1 (en) * 2000-05-12 2003-03-18 The Coca-Cola Company Quality fruit juice beverages having extended quality shelf-life and methods of making the same
US20020132780A1 (en) 2001-01-12 2002-09-19 Heisey Matthew Thomas Low carbohydrate compositions, kits thereof, and methods of use
US7678387B2 (en) * 2000-06-06 2010-03-16 Capricorn Pharma, Inc. Drug delivery systems
KR100831755B1 (ko) * 2000-11-17 2008-05-23 테이트 앤드 라일 퍼블릭 리미티드 컴파니 슈크랄로즈의 용융 가능한 형태
DE10063940A1 (de) * 2000-12-20 2002-07-04 Thomson Brandt Gmbh Aufzeichnungs- und/oder Wiedergabegerät für optische Aufzeichnungsträger
MXPA03008056A (es) * 2001-03-05 2004-10-15 Johnson & Johnson Composiciones farmaceuticas liquidas con sabor oculto.
US20030031772A1 (en) * 2001-03-28 2003-02-13 Zehner Lee R. Mixtures of fructose and lactose as a low-calorie bulk sweetener with reduced glyemic index
FR2822647B1 (fr) * 2001-03-30 2005-03-04 Roquette Freres Boissons enrichies en fibres
WO2002080704A1 (en) 2001-04-03 2002-10-17 Michigan Biotechnology Institute Composition for improving the taste and sweetness profile of beverages having intense sweeteners
DK1377280T3 (da) * 2001-04-09 2007-10-08 Danisco Usa Inc Fyldmidler som mæthedsfornemmelsesgivende midler
US7815956B2 (en) 2001-04-27 2010-10-19 Pepsico Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products
US20060068072A9 (en) * 2001-04-27 2006-03-30 Pepsico, Inc. Use of erythritol and D-tagatose in diet or reduced-calorie beverages
US20020192350A1 (en) * 2001-04-30 2002-12-19 Hynes Michael P. Food products
CA2446609C (en) 2001-05-01 2011-09-20 Pepsico, Inc. Use of erythritol and d-tagatose in zero- or low-calorie beverages and food products
US20030004211A1 (en) 2001-05-25 2003-01-02 Frank Corsini Carbohydrate modifying agent and drinks containing the modifying agent
US20030049352A1 (en) * 2001-05-31 2003-03-13 Haile Mehansho Fortified drinking water
US20030003212A1 (en) * 2001-06-13 2003-01-02 Givaudan Sa Taste modifiers
DE10130504B4 (de) * 2001-06-25 2005-02-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Xanthin- und Phenazon-Acesulfam-H-Komplexe mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung
US6685971B2 (en) 2001-06-28 2004-02-03 Rongxiang Xu Method and composition for repairing and promoting regeneration of mucosal tissue in the gastrointestinal tract
US20030021874A1 (en) * 2001-07-02 2003-01-30 The Procter & Gamble Co. Stabilized compositions and processes of their preparation
KR100851610B1 (ko) 2001-09-21 2008-08-12 디아이씨 가부시끼가이샤 감미료 및 그 제조 방법
JP2003093014A (ja) 2001-09-26 2003-04-02 Takeda-Kirin Foods Corp 液体甘味料
CA2467285C (en) * 2001-11-30 2011-08-16 Ajinomoto Co., Inc. Crystals of non-natural-type stereoisomer salt of monatin and use thereof
JP2003231622A (ja) 2001-12-04 2003-08-19 Kao Corp 口腔用組成物
JP3843009B2 (ja) 2001-12-19 2006-11-08 東洋精糖株式会社 呈味が改善された経口材、経口材の呈味の改善方法並びに酵素処理イチョウ葉エキスの使用方法
US6998480B2 (en) * 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US7067150B2 (en) 2002-04-16 2006-06-27 Scepter Holdings, Inc. Delivery systems for functional ingredients
WO2003103415A1 (en) 2002-06-07 2003-12-18 Ann De Wees Allen Novel sweetener compositions and methods of use
JP2004073197A (ja) 2002-07-31 2004-03-11 Unitika Ltd 甘味組成物およびそれを含有する食品
US20040058050A1 (en) 2002-09-25 2004-03-25 Peilin Guo Herbal sweetening composition
JP4482270B2 (ja) 2002-10-31 2010-06-16 花王株式会社 口腔用組成物
AU2003298659A1 (en) * 2002-11-15 2004-06-15 Cargill, Incorporated Soluble isoflavone compositions
US20040120900A1 (en) 2002-12-20 2004-06-24 Peter Arsenault Intraoral calculus dissolving gel composition
AU2003901230A0 (en) * 2003-03-18 2003-04-03 Wharton, Geoffrey Mr New generation of electrical plugs and socket systems
US6984732B2 (en) * 2003-03-31 2006-01-10 Mcneil-Ppc, Inc. High-intensity sweetener composition and delivery of same
EP1610627A1 (en) 2003-04-08 2006-01-04 Quest International B.V. Oxigen stable active containing compositions
AU2004202670A1 (en) 2003-06-20 2005-01-13 Kim Friemann Sweetener Composition
AU2003259532A1 (en) 2003-07-31 2005-02-14 Matthew Anthony Hartigan Ready-to-drink formulation containing an active ingredient
US20050037121A1 (en) 2003-08-11 2005-02-17 Susanne Rathjen Mixtures of high fructose corn syrup (HFCS) 42 or HFCS 55 and high-intensity sweeteners with a taste profile of pure sucrose
WO2005046702A1 (ja) 2003-09-19 2005-05-26 Sunstar Inc. 歯槽骨の吸収及び歯根膜喪失を抑制する方法及びそれに用いる内服組成物
US20050146255A1 (en) * 2004-01-06 2005-07-07 Irving Sabo Outdoor storage container having hinged and removable lids
JP4216208B2 (ja) 2004-02-26 2009-01-28 サラヤ株式会社 低エネルギーキャンディ
KR20050088031A (ko) 2004-02-28 2005-09-01 (주)아노니 건강음료 노니주스 혼합제조에 관한 방법
JP2005295953A (ja) 2004-04-15 2005-10-27 Gotoo Corporation:Kk 豆乳又は豆乳粉末を利用した栄養補助食品、ダイエット食品
JP2005304440A (ja) 2004-04-26 2005-11-04 Ajinomoto Co Inc 呈味性の改善された低カロリー飲料および甘味料組成物
US20060013842A1 (en) * 2004-07-15 2006-01-19 Matkin John R Natural mixture of long-chain fatty alcohols and long-chain fatty acids, its obtension from animal and vegetable waxes and its nutraceutical uses
US7641892B2 (en) * 2004-07-29 2010-01-05 Cadburry Adams USA, LLC Tooth whitening compositions and delivery systems therefor
US20060024245A1 (en) * 2004-07-29 2006-02-02 Cadbury Adams, Llc. Tooth whitening compositions and delivery systems therefor
DE602005019587D1 (de) 2004-07-30 2010-04-08 Vb Medicare Pvt Ltd Süssstoffzusammensetzung mit reduziertem kaloriengehalt
US20060034993A1 (en) 2004-08-10 2006-02-16 Katrin Saelzer Compositions for improved mouthfeel in reduced-sugar or sugar-free foodstuffs and associated methods and articles therefrom
BRPI0514283A (pt) * 2004-08-11 2008-06-10 Cadbury Adams Usa Llc composições para aquecimento e sistemas de liberação para as mesmas
WO2006018318A1 (en) * 2004-08-18 2006-02-23 Synthon B.V. Liquid paroxetine compositions
JP4504281B2 (ja) 2004-08-20 2010-07-14 小川香料株式会社 高甘味度甘味料の呈味改善剤
US7641926B2 (en) * 2004-08-25 2010-01-05 Cadbury Adams Usa, Llc Liquid-filled chewing gum composition
JP4783370B2 (ja) * 2004-08-25 2011-09-28 キャドバリー・アダムズ・ユーエスエイ・エルエルシー 液体充填チューインガム組成物
US20060062872A1 (en) * 2004-09-23 2006-03-23 Cadbury Adams Usa Llc Pressurized chewing gum compositions and dispensing method
US20060105021A1 (en) 2004-09-24 2006-05-18 Remington Direct Lp Cholesterol-reducing liquid
WO2006041216A1 (ja) 2004-10-15 2006-04-20 Ajinomoto Co., Inc. 甘味料組成物
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
US20060093720A1 (en) 2004-10-28 2006-05-04 Ed Tatz Pumpable, semi-solid low calorie sugar substitute compositions
JP4344334B2 (ja) 2005-03-04 2009-10-14 佐藤製薬株式会社 ステビア由来甘味物質を含有する甘味料
US7851005B2 (en) 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
MX2007016366A (es) 2005-06-27 2008-03-05 Cargill Inc Composiciones de sustituto de azucar y su uso en alimentos y bebidas.
CN101242807B (zh) 2005-08-12 2014-12-10 洲际大品牌有限责任公司 口腔润湿组合物，包含该组合物的递送系统及其制造方法
US7862845B2 (en) 2005-10-11 2011-01-04 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US20070104848A1 (en) 2005-11-10 2007-05-10 Donald Thrasher Carbonated drink compositions and methods of making the same
AU2006318781B2 (en) 2005-11-23 2012-11-01 The Coca-Cola Company Natural high-potency sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses
WO2007078293A1 (en) 2005-12-30 2007-07-12 Pepsico, Inc. A North Carolina Corporation Shelf-stable beverage composition
EP1806059A2 (en) 2006-01-07 2007-07-11 Nutrinova Nutrition Specialties & Food Ingredients GmbH Improving aspartame stability in edible compositions
KR100852258B1 (ko) 2006-05-18 2008-08-14 전현철 새콤달콤한 콜라겐 감귤 비타 녹차 조성물 및 그 제조방법
US7325585B1 (en) * 2006-05-23 2008-02-05 Giulio Benetti Dental prosthetic forming system
US20080085351A1 (en) * 2006-10-04 2008-04-10 Pepsico, Inc. Calorie reduced beverages employing a blend of neotame and acesulfame-K

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010025001A1 (en) * 2008-08-29 2010-03-04 Tropicana Products, Inc. Naturally sweetened juice beverage products
AU2009286000B2 (en) * 2008-08-29 2012-11-01 Tropicana Products, Inc. Naturally sweetened juice beverage products
EP2330928B1 (en) 2008-08-29 2016-02-24 Tropicana Products, Inc. Naturally sweetened juice beverage products
US9788562B2 (en) 2008-08-29 2017-10-17 Tropicana Products, Inc. Naturally sweetened juice beverage products
WO2011024471A1 (ja) * 2009-08-27 2011-03-03 小川香料株式会社 高甘味度甘味料の呈味改善剤
JP2011045305A (ja) * 2009-08-27 2011-03-10 Ogawa & Co Ltd 高甘味度甘味料の呈味改善剤
CN102146106A (zh) * 2010-02-10 2011-08-10 山东圣旺药业股份有限公司 一种95%含量莱鲍迪苷a的提取方法
US11524268B2 (en) 2016-11-09 2022-12-13 Pepsico, Inc. Carbonated beverage makers, methods, and systems
US12048905B2 (en) 2016-11-09 2024-07-30 Pepsico, Inc. Carbonation cup for carbonated beverage maker

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