|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
HU225496B1
(en)
|
1993-04-07 |
2007-01-29 |
Scios Inc |
Pharmaceutical compositions of prolonged delivery, containing peptides
|
|
US5424286A
(en)
|
1993-05-24 |
1995-06-13 |
Eng; John |
Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
|
|
US5641757A
(en)
|
1994-12-21 |
1997-06-24 |
Ortho Pharmaceutical Corporation |
Stable 2-chloro-2'-deoxyadenosine formulations
|
|
DE69739172D1
(de)
|
1996-08-08 |
2009-01-29 |
Amylin Pharmaceuticals Inc |
Regulation gastrointestinaler beweglichkeit
|
|
DK0944648T3
(da)
|
1996-08-30 |
2007-07-02 |
Novo Nordisk As |
GLP-1 derivater
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
PT1629849E
(pt)
|
1997-01-07 |
2013-07-09 |
Amylin Pharmaceuticals Llc |
Composições farmacêuticas que compreendem exendinas e seus agonistas
|
|
US7312196B2
(en)
|
1997-01-08 |
2007-12-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6410511B2
(en)
|
1997-01-08 |
2002-06-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6723530B1
(en)
|
1997-02-05 |
2004-04-20 |
Amylin Pharmaceuticals, Inc. |
Polynucleotides encoding proexendin, and methods and uses thereof
|
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
AU749914B2
(en)
|
1997-08-08 |
2002-07-04 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
NZ504258A
(en)
|
1997-11-14 |
2002-12-20 |
Amylin Pharmaceuticals Inc |
Exendin 3 and 4 agonist compounds for the treatment of diabetes
|
|
CA2309356C
(en)
|
1997-11-14 |
2010-09-21 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
US7223725B1
(en)
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
|
DK1044015T3
(da)
|
1998-01-09 |
2008-12-08 |
Amylin Pharmaceuticals Inc |
Formuleringer med amylinagonistpeptider og insulin
|
|
US6703359B1
(en)
|
1998-02-13 |
2004-03-09 |
Amylin Pharmaceuticals, Inc. |
Inotropic and diuretic effects of exendin and GLP-1
|
|
EP1056775B1
(en)
|
1998-02-27 |
2010-04-28 |
Novo Nordisk A/S |
Glp-1 derivatives of glp-1 and exendin with protracted profile of action
|
|
EP1950223A3
(en)
|
1998-03-09 |
2009-05-13 |
Zealand Pharma A/S |
Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
|
|
JP4072319B2
(ja)
|
1998-03-13 |
2008-04-09 |
ノヴォ ノルディスク アクティーゼルスカブ |
安定化水溶性ペプチド溶液
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
IL140223A0
(en)
|
1998-06-12 |
2002-02-10 |
Bionebraska Inc |
Compositions containing a compound which binds to glucagon-liked
|
|
DK1105460T3
(da)
|
1998-08-10 |
2010-02-08 |
Us Gov Health & Human Serv |
Differentiering af ikke-insulinproducerende celler til insulinproducerende celler med GLP-1 eller Exendin-4 og anvendelser deraf
|
|
WO2000015224A1
(en)
|
1998-09-17 |
2000-03-23 |
Eli Lilly And Company |
Protein formulations
|
|
US6429197B1
(en)
|
1998-10-08 |
2002-08-06 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
|
|
US6284725B1
(en)
|
1998-10-08 |
2001-09-04 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
|
|
US7259136B2
(en)
|
1999-04-30 |
2007-08-21 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating peripheral vascular disease
|
|
ATE307603T1
(de)
|
1998-12-22 |
2005-11-15 |
Lilly Co Eli |
Lagerstabile flüssige zusammensetzungen von glucagon-ähnlichem peptid-1
|
|
US20030087820A1
(en)
|
1999-01-14 |
2003-05-08 |
Young Andrew A. |
Novel exendin agonist formulations and methods of administration thereof
|
|
US6872700B1
(en)
|
1999-01-14 |
2005-03-29 |
Amylin Pharmaceuticals, Inc. |
Methods for glucagon suppression
|
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
|
EP1140145B2
(en)
|
1999-01-14 |
2019-05-15 |
Amylin Pharmaceuticals, LLC |
Novel exendin agonist formulations and methods of administration thereof
|
|
US6451974B1
(en)
|
1999-03-17 |
2002-09-17 |
Novo Nordisk A/S |
Method of acylating peptides and novel acylating agents
|
|
PL351326A1
(en)
|
1999-03-17 |
2003-04-07 |
Novo Nordisk As |
Method for acylating peptides and novel acylating agents
|
|
CA2372214A1
(en)
|
1999-04-30 |
2000-11-09 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
US6849714B1
(en)
|
1999-05-17 |
2005-02-01 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
CN1191273C
(zh)
|
1999-05-17 |
2005-03-02 |
康久化学公司 |
长效促胰岛肽
|
|
US6887470B1
(en)
|
1999-09-10 |
2005-05-03 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
US6482799B1
(en)
|
1999-05-25 |
2002-11-19 |
The Regents Of The University Of California |
Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
|
|
US6506724B1
(en)
|
1999-06-01 |
2003-01-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus
|
|
US6344180B1
(en)
|
1999-06-15 |
2002-02-05 |
Bionebraska, Inc. |
GLP-1 as a diagnostic test to determine β-cell function and the presence of the condition of IGT and type II diabetes
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US6972319B1
(en)
|
1999-09-28 |
2005-12-06 |
Bayer Pharmaceuticals Corporation |
Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
|
|
GB9930882D0
(en)
|
1999-12-30 |
2000-02-23 |
Nps Allelix Corp |
GLP-2 formulations
|
|
DE60105547T3
(de)
|
2000-01-10 |
2014-12-31 |
Amylin Pharmaceuticals, Llc |
Verwendung von exendinen und deren agonisten zur behandlung von hypertriglyceridämie
|
|
US6579851B2
(en)
|
2000-03-14 |
2003-06-17 |
Amylin Pharmaceuticals, Inc. |
Effects of glucagon-like peptide-1 (7-36) on antro-pyloro-duodenal motility
|
|
CA2380423A1
(en)
|
2000-05-17 |
2001-11-22 |
Bionebraska, Inc. |
Peptide pharmaceutical formulations
|
|
CN1462191B
(zh)
|
2000-05-19 |
2013-07-24 |
埃米林药品公司 |
Glp-1用于制备治疗急性冠脉综合征的药物的用途
|
|
EP1317412A1
(en)
|
2000-08-18 |
2003-06-11 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
|
US7507714B2
(en)
|
2000-09-27 |
2009-03-24 |
Bayer Corporation |
Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
|
|
CA2395165C
(en)
|
2000-10-20 |
2012-05-22 |
Mario Ehlers |
Treatment of hibernating myocardium and diabetic cardiomyopathy with a glp-1 peptide
|
|
US7271149B2
(en)
|
2000-12-07 |
2007-09-18 |
Eli Lilly And Company |
GLP-1 fusion proteins
|
|
MXPA03005135A
(es)
|
2000-12-13 |
2003-12-04 |
Lilly Co Eli |
Regimen de tratamiento cronico usando peptidos insulinotropicos similares al glucagon.
|
|
GB2371227A
(en)
|
2001-01-10 |
2002-07-24 |
Grandis Biotech Gmbh |
Crystallisation - resistant aqueous growth hormone formulations
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
CN1162446C
(zh)
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
|
EP1542712A2
(en)
|
2001-06-01 |
2005-06-22 |
Eli Lilly And Company |
Glp-1 formulations with protracted time action
|
|
WO2003002136A2
(en)
|
2001-06-28 |
2003-01-09 |
Novo Nordisk A/S |
Stable formulation of modified glp-1
|
|
CA2652991A1
(en)
|
2001-07-16 |
2003-11-13 |
Caprotec Bioanalytics Gmbh |
Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
|
|
AU2002317599B2
(en)
|
2001-07-31 |
2008-04-03 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
GLP-1 exendin-4 peptide analogs and uses thereof
|
|
EP1432430A4
(en)
|
2001-08-28 |
2006-05-10 |
Lilly Co Eli |
PREMIXTURES OF GLP-1 AND BASALINSULIN
|
|
EP1448222A4
(en)
|
2001-10-19 |
2006-05-17 |
Lilly Co Eli |
BIPHASIC MIXTURES OF GLP-1 AND INSULIN
|
|
WO2003059934A2
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
ES2500918T3
(es)
|
2001-12-21 |
2014-10-01 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina e interferón beta
|
|
US7105489B2
(en)
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
MXPA04008068A
(es)
|
2002-02-20 |
2004-11-26 |
Lilly Co Eli |
Metodo para administrar moleculas de glp-1.
|
|
JP4583762B2
(ja)
|
2002-02-27 |
2010-11-17 |
イミュネックス・コーポレーション |
ポリペプチド製剤
|
|
DE60325847D1
(de)
|
2002-03-11 |
2009-03-05 |
Caprotec Bioanalytics Gmbh |
Verbindungen und verfahren für die analyse des proteoms
|
|
US7141240B2
(en)
|
2002-03-12 |
2006-11-28 |
Cedars-Sinai Medical Center |
Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
|
|
JP2005535569A
(ja)
|
2002-04-04 |
2005-11-24 |
ノボ・ノルデイスク・エー／エス |
Ｇｌｐ−１アゴニスト及び心臓血管合併症
|
|
US6861236B2
(en)
|
2002-05-24 |
2005-03-01 |
Applied Nanosystems B.V. |
Export and modification of (poly)peptides in the lantibiotic way
|
|
US20040037826A1
(en)
|
2002-06-14 |
2004-02-26 |
Michelsen Birgitte Koch |
Combined use of a modulator of CD3 and a GLP-1 compound
|
|
WO2003105897A1
(en)
|
2002-06-14 |
2003-12-24 |
Novo Nordisk A/S |
Combined use of a modulator of cd3 and a glp-1 compound
|
|
DE10227232A1
(de)
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
|
JP5685355B2
(ja)
|
2002-07-04 |
2015-03-18 |
ジーランド ファーマ アクティーゼルスカブ |
Ｇｌｐ−１および糖尿病の処置方法
|
|
US20070065469A1
(en)
|
2002-07-09 |
2007-03-22 |
Michael Betz |
Liquid formulations with high concentration of human growth hormone (high) comprising glycine
|
|
MXPA05000412A
(es)
|
2002-07-09 |
2005-07-22 |
Sandoz Ag |
Formulacioneks liquidas con una alta concentracion de hormona de crecimiento humana (hgh) que comprenden glicina.
|
|
US20040038865A1
(en)
|
2002-08-01 |
2004-02-26 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
US8372804B2
(en)
|
2007-10-24 |
2013-02-12 |
Mannkind Corporation |
Delivery of active agents
|
|
US20080260838A1
(en)
|
2003-08-01 |
2008-10-23 |
Mannkind Corporation |
Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
|
|
US8377869B2
(en)
|
2007-10-24 |
2013-02-19 |
Mannkind Corporation |
Method of preventing adverse effects by GLP-1
|
|
EP2409686A1
(en)
|
2002-08-01 |
2012-01-25 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
PL403104A1
(pl)
|
2002-08-21 |
2013-05-13 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Sposób otrzymywania kompozycji farmaceutycznej zawierajacej pochodne 8-[3-aminopiperydyn-1-ylo]ksantyny
|
|
EP1546200A2
(en)
|
2002-10-02 |
2005-06-29 |
Zealand Pharma A/S |
Stabilized exendin-4 compounds
|
|
US6969702B2
(en)
|
2002-11-20 |
2005-11-29 |
Neuronova Ab |
Compounds and methods for increasing neurogenesis
|
|
US20050209142A1
(en)
|
2002-11-20 |
2005-09-22 |
Goran Bertilsson |
Compounds and methods for increasing neurogenesis
|
|
CA2506850C
(en)
|
2002-11-20 |
2014-05-13 |
Neuronova Ab |
Compounds and methods for increasing neurogenesis
|
|
US20040209803A1
(en)
|
2002-12-19 |
2004-10-21 |
Alain Baron |
Compositions for the treatment and prevention of nephropathy
|
|
EP1610811A4
(en)
|
2002-12-17 |
2008-03-26 |
Amylin Pharmaceuticals Inc |
PREVENTING AND TREATING CARDIAC ERRORS
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
JP4698579B2
(ja)
|
2003-04-08 |
2011-06-08 |
イエダ リサーチ アンド デベロップメント カンパニー リミテッド |
可逆的ｐｅｇ化薬物
|
|
WO2004089985A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Stable pharmaceutical compositions
|
|
US7259234B2
(en)
|
2003-05-15 |
2007-08-21 |
Trustees Of Tufts College |
Stable analogs of peptide and polypeptide therapeutics
|
|
WO2005000360A2
(en)
|
2003-05-23 |
2005-01-06 |
Nektar Therapeutics Al, Corporation |
Peg derivatives having an amidocarbonate linkage
|
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
|
US8008255B2
(en)
|
2003-05-30 |
2011-08-30 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
|
PL1633390T3
(pl)
|
2003-06-03 |
2012-06-29 |
Novo Nordisk As |
Stabilizowane kompozycje farmaceutyczne peptydu glp-1
|
|
PL1633391T3
(pl)
|
2003-06-03 |
2012-03-30 |
Novo Nordisk As |
Stabilizowane farmaceutycznie kompozycje peptydowe
|
|
ATE541582T1
(de)
|
2003-06-03 |
2012-02-15 |
Novo Nordisk As |
Stabilisierte pharmazeutische glp-1 peptid zusammensetzungen
|
|
ATE529126T1
(de)
|
2003-06-03 |
2011-11-15 |
Novo Nordisk As |
Stabilisierte pharmazeutische peptid zusammensetzungen
|
|
US8921311B2
(en)
|
2003-08-01 |
2014-12-30 |
Mannkind Corporation |
Method for treating hyperglycemia
|
|
EP1660531A2
(en)
|
2003-08-05 |
2006-05-31 |
Novo Nordisk A/S |
Novel insulin derivatives
|
|
EP1664108B1
(en)
|
2003-08-21 |
2009-10-14 |
Novo Nordisk A/S |
Separation of polypeptides comprising a racemized amino acid
|
|
EP1663295A2
(en)
|
2003-09-01 |
2006-06-07 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
US20060247167A1
(en)
|
2003-09-01 |
2006-11-02 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
TW200522976A
(en)
|
2003-09-19 |
2005-07-16 |
Novo Nordisk As |
Novel plasma protein affinity tags
|
|
EP1684793B1
(en)
|
2003-11-13 |
2011-09-21 |
Novo Nordisk A/S |
Pharmaceutical composition comprising an insulinotropic glp-1(7-37) analogue, asp(b28)-insulin, and a surfactant
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
US20050281879A1
(en)
|
2003-11-14 |
2005-12-22 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
US20050106214A1
(en)
|
2003-11-14 |
2005-05-19 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
CA2546843C
(en)
|
2003-11-20 |
2015-01-06 |
Neuronova Ab |
Compounds and methods for increasing neurogenesis
|
|
AU2004290862B2
(en)
|
2003-11-20 |
2010-06-03 |
Novo Nordisk A/S |
Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices
|
|
JP5697831B2
(ja)
|
2003-12-03 |
2015-04-08 |
ノヴォ ノルディスク アー／エス |
単鎖インシュリン
|
|
EP1691841B1
(en)
|
2003-12-10 |
2020-09-09 |
Nektar Therapeutics |
Compositions comprising two different populations of polymer-active agent conjugates
|
|
US20050143303A1
(en)
|
2003-12-26 |
2005-06-30 |
Nastech Pharmaceutical Company Inc. |
Intranasal administration of glucose-regulating peptides
|
|
US20060210614A1
(en)
|
2003-12-26 |
2006-09-21 |
Nastech Pharmaceutical Company Inc. |
Method of treatment of a metabolic disease using intranasal administration of exendin peptide
|
|
WO2007065156A2
(en)
|
2005-12-02 |
2007-06-07 |
Nastech Pharmaceutical Company Inc. |
Pharmaceutical formulation for increased epithelial permeability of glucose-regulating peptide
|
|
EP2417980A1
(en)
|
2004-02-11 |
2012-02-15 |
Amylin Pharmaceuticals Inc. |
Hybrid polypeptides with selectable properties
|
|
EP2335716A3
(en)
|
2004-02-11 |
2011-10-19 |
Amylin Pharmaceuticals Inc. |
Pancreatic polypeptide family motifs and polypeptides comprising the same
|
|
NZ571824A
(en)
|
2004-02-11 |
2010-04-30 |
Amylin Pharmaceuticals Inc |
Amylin family peptides and methods for making and using them
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
US7399744B2
(en)
|
2004-03-04 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Methods for affecting body composition
|
|
US7456254B2
(en)
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
|
US20060110423A1
(en)
|
2004-04-15 |
2006-05-25 |
Wright Steven G |
Polymer-based sustained release device
|
|
KR20100129799A
(ko)
|
2004-04-15 |
2010-12-09 |
알케르메스,인코포레이티드 |
중합체 기재 지속적 방출 방법
|
|
US20090069226A1
(en)
|
2004-05-28 |
2009-03-12 |
Amylin Pharmaceuticals, Inc. |
Transmucosal delivery of peptides and proteins
|
|
WO2005117584A2
(en)
|
2004-05-28 |
2005-12-15 |
Amylin Pharmaceuticals, Inc |
Improved transmucosal delivery of peptides and proteins
|
|
CN1950078A
(zh)
|
2004-06-11 |
2007-04-18 |
诺和诺德公司 |
使用glp－1激动剂抵抗药物诱发的肥胖
|
|
US7534763B2
(en)
*
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
BRPI0513508B1
(pt)
|
2004-07-19 |
2021-06-01 |
Biocon Limited |
Conjugados de insulina-oligômero, formulações e usos desses
|
|
CA2569381A1
(en)
|
2004-07-21 |
2006-08-31 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
EA200700391A1
(ru)
|
2004-08-03 |
2007-10-26 |
Байорексис Текнолоджи, Инк. |
Комбинированное лечение с применением слитых белков трансферрина, содержащих glp-1
|
|
US8710181B2
(en)
|
2004-08-31 |
2014-04-29 |
Novo Nordisk A/S |
Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
|
|
DE102004043153B4
(de)
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
|
EP1791554A2
(en)
|
2004-09-17 |
2007-06-06 |
Novo Nordisk A/S |
Pharmaceutical compositions containing insulin and insulinotropic peptide
|
|
KR101341359B1
(ko)
|
2004-10-01 |
2013-12-13 |
램스코르 인코포레이티드 |
편리하게 이식가능한 서방형 약물 조성물
|
|
EP2330126B1
(en)
|
2004-10-07 |
2015-12-23 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
|
US7595294B2
(en)
|
2004-10-08 |
2009-09-29 |
Transition Therapeutics, Inc. |
Vasoactive intestinal polypeptide pharmaceuticals
|
|
WO2006044531A2
(en)
|
2004-10-13 |
2006-04-27 |
Isis Parmaceuticals, Inc. |
Antisense modulation of ptp1b expression
|
|
US7442682B2
(en)
|
2004-10-19 |
2008-10-28 |
Nitto Denko Corporation |
Transepithelial delivery of peptides with incretin hormone activities
|
|
EP2494983B1
(en)
|
2004-11-12 |
2019-04-24 |
Novo Nordisk A/S |
Stable formulations of glp-1
|
|
CN101056650A
(zh)
|
2004-11-12 |
2007-10-17 |
诺和诺德公司 |
促胰岛素肽的稳定制剂
|
|
JP5248113B2
(ja)
|
2004-11-12 |
2013-07-31 |
ノヴォ ノルディスク アー／エス |
ペプチドの安定な処方
|
|
CN101128487B
(zh)
|
2004-12-02 |
2012-10-10 |
杜门蒂斯有限公司 |
靶向血清白蛋白和glp-1或pyy的双特异性结构域抗体
|
|
AU2005316524B2
(en)
|
2004-12-13 |
2012-01-12 |
Amylin Pharmaceuticals, Llc |
Pancreatic Polypeptide Family motifs, polypeptides and methods comprising the same
|
|
KR101320936B1
(ko)
|
2004-12-21 |
2013-10-23 |
넥타르 테라퓨틱스 |
안정화된 중합체성 티올 시약
|
|
SI1831252T1
(sl)
|
2004-12-22 |
2009-12-31 |
Lilly Co Eli |
Formulacije analogov glp-1 fuzijskih proteinov
|
|
CA2599594A1
(en)
|
2004-12-24 |
2006-07-13 |
Amylin Pharmaceuticals, Inc. |
Use of glp-1 and agonists thereof to prevent cardiac myocyte apoptosis
|
|
ES2541633T3
(es)
|
2005-01-14 |
2015-07-22 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Exendinas modificadas y usos de las mismas
|
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
US20080233053A1
(en)
|
2005-02-07 |
2008-09-25 |
Pharmalight Inc. |
Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
EP1853627A2
(en)
|
2005-02-11 |
2007-11-14 |
Amylin Pharmaceuticals, Inc. |
Gip analog and hybrid polypeptides with selectable properties
|
|
WO2006097535A2
(en)
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Peptide agonists of the glucagon family with secretin like activity
|
|
ATE550032T1
(de)
|
2005-04-11 |
2012-04-15 |
Amylin Pharmaceuticals Inc |
Verwendung von glp-1, exendin und agonisten davon zur verzögerung oder verhinderung von kardialer remodellierung
|
|
CN101163514B
(zh)
|
2005-04-24 |
2012-01-25 |
诺和诺德公司 |
注射装置
|
|
US8097584B2
(en)
|
2005-05-25 |
2012-01-17 |
Novo Nordisk A/S |
Stabilized formulations of insulin that comprise ethylenediamine
|
|
JP5198261B2
(ja)
|
2005-06-06 |
2013-05-15 |
カムルス エービー |
Ｇｌｐ−１類似体製剤
|
|
AU2006258841B2
(en)
|
2005-06-13 |
2012-05-03 |
Imperial Innovations Limited |
Oxyntomodulin analogues and their effects on feeding behaviour
|
|
GB0511986D0
(en)
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
WO2006138572A2
(en)
|
2005-06-16 |
2006-12-28 |
Nektar Therapeutics Al, Corporation |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
|
|
KR20080033439A
(ko)
|
2005-08-04 |
2008-04-16 |
넥타르 테라퓨틱스 에이엘, 코포레이션 |
Ｇ-ｃｓｆ 부분 및 중합체의 컨주게이트
|
|
EP1924293A4
(en)
|
2005-08-06 |
2008-12-24 |
Qinghua Wang |
COMPOSITION AND METHOD FOR THE PREVENTION AND TREATMENT OF DIABETES TYPE I
|
|
CA2617649A1
(en)
|
2005-08-11 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
|
CN105056211A
(zh)
|
2005-08-19 |
2015-11-18 |
安米林药品有限责任公司 |
治疗糖尿病和降低体重的毒蜥外泌肽
|
|
DK1928423T3
(en)
|
2005-09-14 |
2016-02-29 |
Mannkind Corp |
A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
|
|
AU2006292377B2
(en)
|
2005-09-20 |
2011-03-03 |
Emisphere Technologies, Inc. |
Use of a DPP-IV inhibitor to reduce hypoglycemic events
|
|
WO2007047834A2
(en)
|
2005-10-18 |
2007-04-26 |
Biocon Limited |
Oral peptide conjugates for metabolic diseases
|
|
US7687608B2
(en)
|
2005-10-19 |
2010-03-30 |
Smartcells, Inc. |
Methods for reducing the mitogenicity of lectin compositions
|
|
WO2007056362A2
(en)
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
|
US8039432B2
(en)
|
2005-11-09 |
2011-10-18 |
Conjuchem, Llc |
Method of treatment of diabetes and/or obesity with reduced nausea side effect
|
|
CA2632903C
(en)
|
2005-12-02 |
2015-11-24 |
Vianova Labs, Inc. |
Treatment of cancer and other diseases
|
|
JP2009520693A
(ja)
|
2005-12-08 |
2009-05-28 |
エムディーアールエヌエー，インコーポレイテッド |
安定化されたエキセンディン製剤の粘膜送達
|
|
JP5096363B2
(ja)
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Ｇｌｐ−１のポリマ複合体
|
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
|
CA2634034A1
(en)
|
2005-12-20 |
2007-06-28 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
MX2008009125A
(es)
|
2006-01-18 |
2008-10-23 |
Qps Llc |
Composiciones farmaceuticas con estabilidad mejorada.
|
|
EP1988922A4
(en)
|
2006-02-03 |
2010-06-02 |
Medimmune Llc |
PROTEIN FORMULATIONS
|
|
US7704953B2
(en)
|
2006-02-17 |
2010-04-27 |
Mdrna, Inc. |
Phage displayed cell binding peptides
|
|
WO2007109354A2
(en)
|
2006-03-21 |
2007-09-27 |
Amylin Pharmaceuticals, Inc. |
Peptide-peptidase inhibitor conjugates and methods of using same
|
|
CN101466394A
(zh)
|
2006-04-13 |
2009-06-24 |
科学研究和应用咨询股份公司 |
hGLP-1、胰高血糖素样肽的抑制剂-4及其类似物的药物组合物
|
|
MX2008013216A
(es)
|
2006-04-14 |
2008-10-27 |
Mannkind Corp |
Formulaciones farmaceuticas de peptido-1 tipo glucagon (glp-1).
|
|
DE202006006388U1
(de)
|
2006-04-20 |
2007-08-30 |
Tegometall (International) Ag |
Regal-Fachboden
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
WO2007133778A2
(en)
|
2006-05-12 |
2007-11-22 |
Amylin Pharmaceuticals, Inc. |
Methods to restore glycemic control
|
|
US20100022457A1
(en)
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
AU2007267833B2
(en)
|
2006-05-26 |
2012-07-26 |
Amylin Pharmaceuticals, Llc |
Composition and methods for treatment of congestive heart failure
|
|
DK2038423T3
(da)
|
2006-06-21 |
2013-04-02 |
Biocon Ltd |
Fremgangsmåde til fremstilling af biologisk aktive polypeptider med insulinotropisk aktivitet
|
|
ES2530390T3
(es)
|
2006-07-05 |
2015-03-02 |
Foamix Pharmaceuticals Ltd |
Vehículo espumante de ácido carboxílico y composiciones farmacéuticas del mismo
|
|
EP2046826B1
(en)
|
2006-07-24 |
2011-09-14 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
|
US7928186B2
(en)
|
2006-08-02 |
2011-04-19 |
Phoenix Pharmaceuticals, Inc. |
Cell permeable bioactive peptide conjugates
|
|
CA2660029A1
(en)
|
2006-08-04 |
2008-02-07 |
Nastech Pharmaceutical Company Inc. |
Compositions for intranasal delivery of human insulin and uses thereof
|
|
NZ574524A
(en)
|
2006-08-09 |
2011-07-29 |
Intarcia Therapeutics Inc |
Piston assembly for positioning lumen of a reservoir for an osmotic delivery having a columnar body and a spring
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
WO2008021560A2
(en)
|
2006-08-17 |
2008-02-21 |
Amylin Pharmaceuticals, Inc. |
Dpp-iv resistant gip hybrid polypeptides with selectable properties
|
|
WO2008023050A1
(en)
|
2006-08-25 |
2008-02-28 |
Novo Nordisk A/S |
Acylated exendin-4 compounds
|
|
CN102827284B
(zh)
|
2006-11-14 |
2015-07-29 |
上海仁会生物制药股份有限公司 |
带有聚乙二醇基团的Exendin或其类似物及其制剂和用途
|
|
US20100168011A1
(en)
|
2006-12-12 |
2010-07-01 |
Amylin Pharmaceuticals, Inc. |
Pharmaceutical Formulations and Methods for Making the Same
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
WO2008086086A2
(en)
|
2007-01-05 |
2008-07-17 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
|
US20090098130A1
(en)
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
|
RU2432361C2
(ru)
|
2007-01-05 |
2011-10-27 |
КовЭкс Текнолоджиз Айэлэнд Лимитед |
Соединения агонисты рецептора глюкагоноподобного белка-1 (glp-1r)
|
|
CN101663317A
(zh)
|
2007-01-05 |
2010-03-03 |
CovX科技爱尔兰有限公司 |
胰高血糖素样蛋白-1受体glp-1r激动剂化合物
|
|
WO2008098212A2
(en)
|
2007-02-08 |
2008-08-14 |
Diobex, Inc. |
Extended release formulations of glucagon and other peptides and proteins
|
|
EA017849B1
(ru)
|
2007-02-15 |
2013-03-29 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Соагонисты глюкагоновых/glp-1-рецепторов
|
|
WO2008130066A1
(en)
|
2007-04-20 |
2008-10-30 |
Kang Choon Lee |
Mono modified exendin with polyethylene glycol or its derivatives and uses thereof
|
|
AU2008244523B2
(en)
|
2007-04-23 |
2012-02-16 |
Intarcia Therapeutics, Inc. |
Suspension formulations of insulinotropic peptides and uses thereof
|
|
WO2008134425A1
(en)
|
2007-04-27 |
2008-11-06 |
Cedars-Sinai Medical Center |
Use of glp-1 receptor agonists for the treatment of gastrointestinal disorders
|
|
US7829664B2
(en)
|
2007-06-01 |
2010-11-09 |
Boehringer Ingelheim International Gmbh |
Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
|
|
CA2689909C
(en)
|
2007-06-08 |
2016-04-05 |
Ascendis Pharma As |
Long-acting polymeric prodrugs of exendin
|
|
JP5385266B2
(ja)
|
2007-06-15 |
2014-01-08 |
ジーランド ファーマ アクティーゼルスカブ |
グルカゴン類似体
|
|
WO2009009562A2
(en)
|
2007-07-10 |
2009-01-15 |
Eli Lilly And Company |
Glp-1-fc fusion protein formulation
|
|
WO2009020802A2
(en)
|
2007-08-03 |
2009-02-12 |
Eli Lilly And Company |
Treatment for obesity
|
|
CN101366692A
(zh)
|
2007-08-15 |
2009-02-18 |
江苏豪森药业股份有限公司 |
一种稳定的艾塞那肽制剂
|
|
NZ599755A
(en)
|
2007-08-30 |
2013-08-30 |
Curedm Group Holdings Llc |
Compositions and methods of using proislet peptides and analogs thereof
|
|
US20100261637A1
(en)
|
2007-09-05 |
2010-10-14 |
Novo Nordisk A/S |
Peptides derivatized with a-b-c-d- and their therapeutical use
|
|
US20100256056A1
(en)
|
2007-09-07 |
2010-10-07 |
Zheng Xin Dong |
Analogues of exendin-4 and exendin-3
|
|
US8785396B2
(en)
|
2007-10-24 |
2014-07-22 |
Mannkind Corporation |
Method and composition for treating migraines
|
|
ES2509883T3
(es)
|
2007-10-30 |
2014-10-20 |
Indiana University Research And Technology Corporation |
Antagonistas de glucagón
|
|
EP2214691B1
(en)
|
2007-10-30 |
2015-09-30 |
Indiana University Research and Technology Corporation |
Compounds exhibiting glucagon antagonist and glp-1 agonist activity
|
|
BRPI0820535B8
(pt)
|
2007-11-16 |
2021-05-25 |
Novo Nordisk As |
composições farmacêuticas contendo insulina e um peptídeo insulinotrópico
|
|
US8710002B2
(en)
|
2007-11-23 |
2014-04-29 |
Michael Rothkopf |
Methods of enhancing diabetes resolution
|
|
CN101444618B
(zh)
|
2007-11-26 |
2012-06-13 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
CA2708762A1
(en)
|
2007-12-11 |
2009-06-18 |
Conjuchem Biotechnologies Inc. |
Formulation of insulinotropic peptide conjugates
|
|
JP2011511778A
(ja)
|
2008-01-30 |
2011-04-14 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション |
エステルに基づいたペプチドプロドラッグ
|
|
PL2237799T3
(pl)
|
2008-02-01 |
2019-09-30 |
Ascendis Pharma A/S |
Prolek zawierający samorozszczepiający się łącznik
|
|
MY161108A
(en)
|
2008-02-06 |
2017-04-14 |
Biocon Ltd |
Fermentation medias and processes thereof
|
|
WO2009114959A1
(zh)
|
2008-03-20 |
2009-09-24 |
中国人民解放军军事医学科学院毒物药物研究所 |
可注射用缓释药物制剂及其制备方法
|
|
WO2009125423A2
(en)
|
2008-04-07 |
2009-10-15 |
National Institute Of Immunology |
Compositions useful for the treatment of diabetes and other chronic disorder
|
|
WO2009137080A1
(en)
|
2008-05-07 |
2009-11-12 |
Merrion Research Iii Limited |
Compositions of gnrh related compounds and processes of preparation
|
|
US20110263496A1
(en)
|
2008-05-21 |
2011-10-27 |
Amylin Pharmaceuticals, Inc. |
Exendins to lower cholesterol and triglycerides
|
|
WO2009143014A1
(en)
|
2008-05-23 |
2009-11-26 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist bioassays
|
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
|
PL2293833T3
(pl)
|
2008-06-13 |
2016-08-31 |
Mannkind Corp |
Inhalator proszkowy i układ do dostarczania leku
|
|
ES2579502T3
(es)
|
2008-06-17 |
2016-08-11 |
Indiana University Research And Technology Corporation |
Coagonistas de receptores de glucagón/GLP-1
|
|
ES2650038T3
(es)
|
2008-06-17 |
2018-01-16 |
Indiana University Research And Technology Corporation |
Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad
|
|
AU2009261441B2
(en)
|
2008-06-17 |
2013-01-10 |
Glytech, Inc. |
Oligosaccharide chain added glp-1 peptide
|
|
JP5753779B2
(ja)
|
2008-06-17 |
2015-07-22 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ |
生理学的ｐＨの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体
|
|
EP3412300A1
(en)
|
2008-06-27 |
2018-12-12 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
|
CA2731236A1
(en)
|
2008-07-21 |
2010-01-28 |
Transpharma Medical Ltd. |
Transdermal system for extended delivery of incretins and incretin mimetic peptides
|
|
WO2010013012A2
(en)
|
2008-08-01 |
2010-02-04 |
Lund University Bioscience Ab |
Novel polypeptides and uses thereof
|
|
CN101670096B
(zh)
|
2008-09-11 |
2013-01-16 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
PT2349324T
(pt)
|
2008-10-17 |
2017-12-06 |
Sanofi Aventis Deutschland |
Combinação de uma insulina e de um agonista do glp-1
|
|
SI2373681T1
(sl)
|
2008-12-10 |
2017-05-31 |
Glaxosmithkline Llc Corporation Service Company |
Farmacevtski sestavki albiglutida
|
|
CA2747109A1
(en)
|
2008-12-15 |
2010-06-24 |
Zealand Pharma A/S |
Glucagon analogues
|
|
EA020497B1
(ru)
|
2008-12-15 |
2014-11-28 |
Зилэнд Фарма А/С |
Аналоги глюкагона
|
|
PL2370462T3
(pl)
|
2008-12-15 |
2015-01-30 |
Zealand Pharma As |
Analogi glukagonu
|
|
US8642540B2
(en)
|
2008-12-15 |
2014-02-04 |
Zealand Pharma A/S |
Glucagon analogues
|
|
SG172291A1
(en)
|
2008-12-19 |
2011-07-28 |
Univ Indiana Res & Tech Corp |
Amide based glucagon superfamily peptide prodrugs
|
|
CN101538323B
(zh)
|
2009-01-13 |
2012-05-09 |
深圳翰宇药业股份有限公司 |
一种纯化艾塞那肽的方法
|
|
WO2010096052A1
(en)
|
2009-02-19 |
2010-08-26 |
Merck Sharp & Dohme Corp. |
Oxyntomodulin analogs
|
|
CN102438602B
(zh)
|
2009-03-04 |
2016-04-13 |
曼金德公司 |
改进的干燥粉末药物输送系统
|
|
JP5608686B2
(ja)
|
2009-03-05 |
2014-10-15 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
後退可能な針を備えた薬物送達デバイス
|
|
US8642544B2
(en)
|
2009-04-01 |
2014-02-04 |
Amylin Pharmaceuticals, Llc |
N-terminus conformationally constrained GLP-1 receptor agonist compounds
|
|
WO2010118034A2
(en)
|
2009-04-06 |
2010-10-14 |
Board Of Regents, The University Of Texas System |
Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells
|
|
RU2503688C2
(ru)
|
2009-04-22 |
2014-01-10 |
Алтеоген, Инк |
Слитый белок или пептид с увеличенным временем полужизни in vivo, поддерживаемый за счет замедленного высвобождения in vivo, и способ увеличения времени полужизни in vivo с его применением
|
|
CN101870728A
(zh)
|
2009-04-23 |
2010-10-27 |
派格生物医药(苏州)有限公司 |
新型Exendin变体及其缀合物
|
|
CN101559041B
(zh)
|
2009-05-19 |
2014-01-15 |
中国科学院过程工程研究所 |
粒径均一的多肽药物缓释微球或微囊制剂及制备方法
|
|
CN102438679B
(zh)
|
2009-05-20 |
2016-03-09 |
赛诺菲-安万特德国有限公司 |
用于药物递送装置中药物容纳筒的塞子
|
|
EP2432527B1
(en)
|
2009-05-20 |
2019-10-02 |
Sanofi-Aventis Deutschland GmbH |
A system comprising a drug delivery device and a cartridge provided with a bung and a method of identifying the cartridge
|
|
EP2435061A4
(en)
|
2009-05-28 |
2013-03-27 |
Amylin Pharmaceuticals Inc |
DAMPING GLP-1 RECEPTOR AGONIST COMPOUNDS
|
|
JP2012529463A
(ja)
|
2009-06-11 |
2012-11-22 |
ノヴォ ノルディスク アー／エス |
２型糖尿病を治療するための、ｇｌｐ−１とｆｇｆ２１との組合せ
|
|
JP5887265B2
(ja)
|
2009-06-16 |
2016-03-16 |
インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション |
Ｇｉｐ受容体活性グルカゴン化合物
|
|
IN2012DN00248A
(es)
|
2009-07-02 |
2015-05-01 |
Angiochem Inc |
|
|
EA022816B1
(ru)
|
2009-07-13 |
2016-03-31 |
Зилэнд Фарма А/С |
Ацилированные аналоги глюкагона
|
|
CN101601646B
(zh)
|
2009-07-22 |
2011-03-23 |
南京凯瑞尔纳米生物技术有限公司 |
治疗糖尿病的鼻腔滴剂及其制备方法
|
|
WO2011011675A1
(en)
|
2009-07-23 |
2011-01-27 |
Zelos Therapeutics, Inc. |
Pharmaceutically acceptable formulations/compositions for peptidyl drugs
|
|
KR20120089843A
(ko)
|
2009-07-31 |
2012-08-14 |
사노피-아벤티스 도이칠란트 게엠베하 |
인슐린 링커 접합체를 포함한 프로드럭
|
|
WO2011017835A1
(en)
|
2009-08-11 |
2011-02-17 |
Nanjing University |
Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding
|
|
CN101993485B
(zh)
|
2009-08-20 |
2013-04-17 |
重庆富进生物医药有限公司 |
促胰岛素分泌肽类似物同源二聚体及其用途
|
|
US20120148586A1
(en)
|
2009-08-27 |
2012-06-14 |
Joyce Ching Tsu Chou |
Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
|
|
SG10201406063XA
(en)
|
2009-09-30 |
2014-11-27 |
Glaxo Group Ltd |
Drug fusions and conjugates with extended half life
|
|
US20110097386A1
(en)
|
2009-10-22 |
2011-04-28 |
Biodel, Inc. |
Stabilized glucagon solutions
|
|
DK2490708T3
(da)
|
2009-10-22 |
2013-04-15 |
Biodel Inc |
Stabiliserede glucagon-opløsninger
|
|
US9610329B2
(en)
|
2009-10-22 |
2017-04-04 |
Albireo Pharma, Inc. |
Stabilized glucagon solutions
|
|
EP2495255A4
(en)
|
2009-10-30 |
2013-05-15 |
Otsuka Chemical Co Ltd |
GLYCOSYLATED FORM OF AN ANTIGENIC GLP-1 ANALOG
|
|
US20120294855A1
(en)
|
2009-11-03 |
2012-11-22 |
Eli Lilly & Company |
Glp-1 receptor agonist compounds for obstructive sleep apnea
|
|
PL2498802T3
(pl)
|
2009-11-13 |
2015-06-30 |
Sanofi Aventis Deutschland |
Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę
|
|
EP2498801B1
(de)
|
2009-11-13 |
2018-01-24 |
Sanofi-Aventis Deutschland GmbH |
HARMAZEUTISCHE ZUSAMMENSETZUNG UMFASSEND desPro36Exendin-4(1-39)-Lys6-NH2 UND METHIONIN
|
|
EP2512475A1
(en)
|
2009-12-15 |
2012-10-24 |
Metabolic Solutions Development Company LLC |
Ppar-sparing thiazolidinediones and combinations for the treatment of obesity and other metabolic diseases
|
|
RU2570424C2
(ru)
|
2009-12-15 |
2015-12-10 |
МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи |
Рапп-поддерживающие тиазолидиндионы и их комбинации для лечения нейродегенеративных заболеваний
|
|
PL2513070T3
(pl)
|
2009-12-15 |
2018-05-30 |
Cirius Therapeutics, Inc. |
Oszczędzające ppar sole tiazolidynodionu do leczenia chorób metabolicznych
|
|
AU2010340058A1
(en)
|
2009-12-15 |
2012-06-21 |
Metabolic Solutions Development Company, Llc |
PPAR-sparing thiazolidinediones and combinations for the treatment of diabetes mellitus and other metabolic diseases
|
|
CN102791731B
(zh)
|
2009-12-16 |
2016-04-20 |
诺沃—诺迪斯克有限公司 |
Glp-1类似物和衍生物
|
|
CN102933200B
(zh)
|
2009-12-18 |
2015-11-25 |
莱迪杜德制药公司 |
包含磷脂的单相凝胶组合物
|
|
EP2512503A4
(en)
|
2009-12-18 |
2013-08-21 |
Univ Indiana Res & Tech Corp |
COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR
|
|
CN101798588B
(zh)
|
2009-12-21 |
2015-09-09 |
上海仁会生物制药股份有限公司 |
Glp-1受体激动剂生物学活性测定方法
|
|
AR079345A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina
|
|
AR079344A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad
|
|
MX342409B
(es)
|
2010-01-20 |
2016-09-28 |
Zealand Pharma As |
Tratamiento de enfermedades cardiacas.
|
|
RU2012136450A
(ru)
|
2010-01-27 |
2014-03-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения
|
|
US9775949B2
(en)
|
2010-02-01 |
2017-10-03 |
Sanofi-Aventis Deutschland Gmbh |
Cartridge holder, drug delivery device and method for securing a cartridge in a cartridge holder
|
|
WO2011109784A1
(en)
|
2010-03-05 |
2011-09-09 |
Conjuchem, Llc |
Formulation of insulinotropic peptide conjugates
|
|
AR080592A1
(es)
|
2010-03-26 |
2012-04-18 |
Lilly Co Eli |
Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso
|
|
RU2559320C2
(ru)
|
2010-03-26 |
2015-08-10 |
Ново Нордиск А/С |
Новые аналоги глюкагона
|
|
CA2797095A1
(en)
|
2010-05-13 |
2011-11-17 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
|
|
BR112012028707A2
(pt)
|
2010-05-13 |
2019-09-24 |
Univ Indiana Res & Tech Corp |
composto de glucagon da superfamília de peptídeos exibindo atividade do receptor g com proteína acoplada, pró farmaco, dímero ou multímro, composição farmacêutica que o compreendem e método de administração do mesmo.
|
|
AU2011202239C1
(en)
|
2010-05-19 |
2017-03-16 |
Sanofi |
Long-acting formulations of insulins
|
|
BR112012029280A2
(pt)
|
2010-05-20 |
2016-11-29 |
Glaxo Group Ltd |
variante de domínio variável único de imunoglobulina antialbumina sérica, imunoglobulina anti-sa, ligando multiespecífico, proteína de fusão, composição, ácido nucleico, vetor, célula hospedeira isolada, e, uso de uma variante, ligando multiespecífico ou proteína de fusão
|
|
WO2011156407A2
(en)
|
2010-06-09 |
2011-12-15 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists to treat pancre-atitis
|
|
CN101891823B
(zh)
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
|
US8636711B2
(en)
|
2010-06-14 |
2014-01-28 |
Legacy Emanuel Hospital & Health Center |
Stabilized glucagon solutions and uses therefor
|
|
MX359281B
(es)
|
2010-06-21 |
2018-09-21 |
Mannkind Corp |
Sistema y metodos para suministrar un farmaco en polvo seco.
|
|
UY33462A
(es)
|
2010-06-23 |
2012-01-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
US9234023B2
(en)
|
2010-06-24 |
2016-01-12 |
Biousian Biosystems, Inc. |
Glucagon-like peptide-1 glycopeptides
|
|
KR20130102470A
(ko)
|
2010-06-24 |
2013-09-17 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
아미드계 글루카곤 슈퍼패밀리 펩티드 프로드러그
|
|
US20120046225A1
(en)
|
2010-07-19 |
2012-02-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Stable glucagon formulations for the treatment of hypoglycemia
|
|
WO2012012352A2
(en)
|
2010-07-19 |
2012-01-26 |
Amidebio, Llc |
Modified peptides and proteins
|
|
MX2013001131A
(es)
|
2010-07-28 |
2013-10-17 |
Amylin Pharmaceuticals Llc |
Compuestos agonistas del receptor del peptido similar al glucagon tipo 1 que tienen regiones estabilizadas.
|
|
CN102397558B
(zh)
|
2010-09-09 |
2013-08-14 |
中国人民解放军军事医学科学院毒物药物研究所 |
Exendin-4类似物的定位聚乙二醇化修饰物及其用途
|
|
EP2438930A1
(en)
|
2010-09-17 |
2012-04-11 |
Sanofi-Aventis Deutschland GmbH |
Prodrugs comprising an exendin linker conjugate
|
|
BR112013007442A2
(pt)
|
2010-09-28 |
2019-09-24 |
Amylin Pharmaceuticals Llc |
polipeptídeos construídos tendo duração de ação realçada
|
|
WO2012059764A1
(en)
|
2010-11-03 |
2012-05-10 |
Arecor Limited |
Novel composition comprising glucagon
|
|
EP2637657B1
(en)
|
2010-11-09 |
2019-05-22 |
MannKind Corporation |
Composition comprising a serotonin receptor agonist and a diketopiperazine for treating migraines
|
|
EP2460552A1
(en)
|
2010-12-06 |
2012-06-06 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device with locking arrangement for dose button
|
|
EP3326620B1
(en)
|
2010-12-16 |
2020-03-04 |
Novo Nordisk A/S |
Solid compositions comprising a glp-1 agonist and a salt of n-(8-(2- hydroxybenzoyl)amino)caprylic acid
|
|
EA201390941A1
(ru)
|
2010-12-22 |
2013-12-30 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Аналоги глюкагона, проявляющие активность на рецепторе gip
|
|
WO2012088157A2
(en)
|
2010-12-22 |
2012-06-28 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists for islet cell transplantation
|
|
CN102532301B
(zh)
|
2010-12-31 |
2014-09-03 |
上海医药工业研究院 |
一类新型的Exendin-4类似物及其制备方法
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
CN102100906A
(zh)
|
2011-02-18 |
2011-06-22 |
深圳翰宇药业股份有限公司 |
一种艾塞那肽的药用制剂及其制备方法
|
|
SG193389A1
(en)
|
2011-03-10 |
2013-10-30 |
Xeris Pharmaceuticals Inc |
Stable formulations for parenteral injection of peptide drugs
|
|
CN102718858B
(zh)
|
2011-03-29 |
2014-07-02 |
天津药物研究院 |
胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
|
|
CN106928341B
(zh)
|
2011-03-30 |
2021-06-01 |
上海仁会生物制药股份有限公司 |
定点单取代聚乙二醇化Exendin类似物及其制备方法
|
|
US9790262B2
(en)
|
2011-04-05 |
2017-10-17 |
Longevity Biotech, Inc. |
Compositions comprising glucagon analogs and methods of making and using the same
|
|
EP2696897A2
(en)
|
2011-04-11 |
2014-02-19 |
Yeda Research and Development Co. Ltd. |
Albumin binding probes and drug conjugates thereof
|
|
WO2012150503A2
(en)
|
2011-05-03 |
2012-11-08 |
Zealand Pharma A/S |
Glu-glp-1 dual agonist signaling-selective compounds
|
|
CN102766204B
(zh)
|
2011-05-05 |
2014-10-15 |
天津药物研究院 |
胰高血糖素样肽-1突变体多肽及其制备方法和其应用
|
|
KR102011924B1
(ko)
|
2011-05-18 |
2019-08-21 |
메더리스 다이어비티즈, 엘엘씨 |
인슐린 저항성에 대한 개선된 펩티드 제약
|
|
US20140221282A1
(en)
|
2011-05-25 |
2014-08-07 |
Astrazeneca Pharmaceuticals Lp |
Long duration dual hormone conjugates
|
|
DE102011102879B4
(de)
|
2011-05-31 |
2014-03-27 |
Pewag Schneeketten Gmbh & Co Kg |
Kettenglied für Gleitschutzketten für Fahrzeugreifen, sowie Gleitschutzkette umfassend solche Kettenglieder
|
|
UA113626C2
(xx)
*
|
2011-06-02 |
2017-02-27 |
|
Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
|
|
DK3434687T3
(da)
|
2011-06-10 |
2021-06-07 |
Hanmi Science Co Ltd |
Hidtil ukendte oxyntomodulinderivater og farmaceutisk præparat til behandling af fedme omfattende samme
|
|
US9453062B2
(en)
|
2011-06-10 |
2016-09-27 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof
|
|
PE20181268A1
(es)
|
2011-06-17 |
2018-08-03 |
Hanmi Science Co Ltd |
Un conjugado que comprende oxintomodulina y un fragmento de inmunoglobulina, y el uso del mismo
|
|
US9309301B2
(en)
|
2011-06-22 |
2016-04-12 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
|
GEP20176629B
(en)
|
2011-06-22 |
2017-02-27 |
Indiana Unversity Research And Tech Corporation |
Glucagon/glp-1 receptor co-agonists
|
|
US20140220134A1
(en)
|
2011-06-24 |
2014-08-07 |
Astrazeneca Pharamceuticals LP |
Method for treating diabetes with extended release formulation of glp-1 receptor agonists
|
|
KR101357117B1
(ko)
|
2011-06-28 |
2014-02-06 |
비앤엘델리팜 주식회사 |
폴리에틸렌글라이콜 또는 이의 유도체로 페길화된 엑센딘-4 유사체, 이의 제조방법 및 이를 유효성분으로 함유하는 당뇨병 예방 또는 치료용 약학적 조성물
|
|
WO2013004983A1
(en)
|
2011-07-04 |
2013-01-10 |
Imperial Innovations Limited |
Novel compounds and their effects on feeding behaviour
|
|
US9382304B2
(en)
|
2011-07-08 |
2016-07-05 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides having enhanced duration of action with reduced immunogenicity
|
|
AU2012293463B2
(en)
|
2011-08-10 |
2016-08-04 |
Adocia |
Injectable solution of at least one type of basal insulin
|
|
US20130084277A1
(en)
|
2011-08-24 |
2013-04-04 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
|
WO2013029279A1
(zh)
|
2011-09-03 |
2013-03-07 |
深圳市健元医药科技有限公司 |
新的glp-ⅰ类似物及其制备方法和用途
|
|
JP6352806B2
(ja)
|
2011-09-23 |
2018-07-04 |
ノヴォ ノルディスク アー／エス |
新規のグルカゴン類似体
|
|
US20130296236A1
(en)
|
2011-10-28 |
2013-11-07 |
Louise SILVESTRE |
Treatment protocol of diabetes type 2
|
|
CN102363633B
(zh)
|
2011-11-16 |
2013-11-20 |
天津拓飞生物科技有限公司 |
胰高血糖素样肽-1突变体多肽及其制备方法、药物组合物和其应用
|
|
CA2847246A1
(en)
|
2011-11-17 |
2013-05-23 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
|
|
EP3446692A1
(en)
|
2011-11-29 |
2019-02-27 |
Jurox Pty. Ltd. |
Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
|
|
LT2791160T
(lt)
|
2011-12-16 |
2022-06-10 |
Modernatx, Inc. |
Modifikuotos mrnr sudėtys
|
|
KR101640697B1
(ko)
|
2011-12-22 |
2016-07-18 |
화이자 인코포레이티드 |
항당뇨병 화합물
|
|
EP2793931A2
(en)
|
2011-12-23 |
2014-10-29 |
Zealand Pharma A/S |
Glucagon analogues
|
|
JP2015503565A
(ja)
|
2011-12-29 |
2015-02-02 |
ラティチュード ファーマシューティカルズ インコーポレイテッドＬａｔｉｔｕｄｅ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
安定化させたグルカゴンナノエマルジョン
|
|
BR112014016889A8
(pt)
|
2012-01-09 |
2017-07-04 |
Adocia |
composição sob a forma de uma solução aquosa injetável, sujo ph está compreendido entre 6,0 e 8,0 e, formulação de dose unitária com ph compreendido entre 7 e 7,8
|
|
WO2013148871A1
(en)
|
2012-03-28 |
2013-10-03 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides
|
|
WO2013148966A1
(en)
|
2012-03-28 |
2013-10-03 |
Amylin Pharmaceuticals, Llc |
Transmucosal delivery of engineered polypeptides
|
|
US9192651B2
(en)
|
2012-04-02 |
2015-11-24 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
|
CA2868391A1
(en)
|
2012-04-02 |
2013-10-10 |
Stephane Bancel |
Polynucleotides comprising n1-methyl-pseudouridine and methods for preparing the same
|
|
WO2013163162A1
(en)
|
2012-04-24 |
2013-10-31 |
Amylin Pharmaceuticals, Llc |
Site-specific enzymatic modification of exendins and analogs thereof
|
|
US20130289241A1
(en)
|
2012-04-26 |
2013-10-31 |
Shanghai Ambiopharm, Inc. |
Method for preparing exenatide
|
|
WO2013182217A1
(en)
|
2012-04-27 |
2013-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
US8901484B2
(en)
|
2012-04-27 |
2014-12-02 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
US9453064B2
(en)
|
2012-05-03 |
2016-09-27 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (GLP-2) analogues
|
|
EP2664374A1
(en)
|
2012-05-15 |
2013-11-20 |
F. Hoffmann-La Roche AG |
Lysin-glutamic acid dipeptide derivatives
|
|
CN103421094A
(zh)
|
2012-05-24 |
2013-12-04 |
上海医药工业研究院 |
一种具有epo类似活性的多肽化合物
|
|
US20150090935A1
(en)
|
2012-05-25 |
2015-04-02 |
Merck Patent Gmbh |
Bimesogenic compounds and mesogenic media
|
|
WO2013177565A1
(en)
|
2012-05-25 |
2013-11-28 |
Amylin Pharmaceuticals, Llc |
Insulin-pramlintide compositions and methods for making and using them
|
|
WO2013186240A2
(en)
|
2012-06-14 |
2013-12-19 |
Sanofi |
Exendin-4 peptide analogues
|
|
SG11201408491SA
(en)
|
2012-06-21 |
2015-01-29 |
Univ Indiana Res & Tech Corp |
Analogs of glucagon exhibiting gip receptor activity
|
|
CA2878457C
(en)
|
2012-07-12 |
2021-01-19 |
Mannkind Corporation |
Dry powder drug delivery systems and methods
|
|
PL2875043T3
(pl)
|
2012-07-23 |
2017-06-30 |
Zealand Pharma A/S |
Analogi glukagonu
|
|
AR092862A1
(es)
|
2012-07-25 |
2015-05-06 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
|
|
KR101968344B1
(ko)
|
2012-07-25 |
2019-04-12 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
|
|
AR094821A1
(es)
|
2012-07-25 |
2015-09-02 |
Hanmi Pharm Ind Co Ltd |
Formulación líquida de un conjugado de péptido insulinotrópico de acción prolongada
|
|
WO2014027254A1
(en)
|
2012-08-14 |
2014-02-20 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
WO2014027253A1
(en)
|
2012-08-14 |
2014-02-20 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
CN102816244A
(zh)
|
2012-08-23 |
2012-12-12 |
无锡和邦生物科技有限公司 |
一种Exendin-4肽与人血清白蛋白HSA的融合蛋白及其制备方法
|
|
CN102827270A
(zh)
|
2012-09-13 |
2012-12-19 |
无锡和邦生物科技有限公司 |
一种聚乙二醇化艾塞那肽衍生物及其用途
|
|
US9546205B2
(en)
|
2012-09-17 |
2017-01-17 |
Imperial Innovations Limited |
Peptide analogues of glucagon and GLP1
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
KR101993393B1
(ko)
|
2012-11-06 |
2019-10-01 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
|
|
PH12018501454A1
(en)
|
2012-11-06 |
2020-02-17 |
Hanmi Pharm Ind Co Ltd |
Liquid formulation of protein conjugate comprising the oxyntomodulin and an immunoglubin fragment
|
|
JP6525456B2
(ja)
|
2012-11-20 |
2019-06-05 |
メデリス ダイアビーティーズ，エルエルシー |
インスリン抵抗性のための改善されたペプチド製剤
|
|
TWI674270B
(zh)
|
2012-12-11 |
2019-10-11 |
英商梅迪繆思有限公司 |
用於治療肥胖之升糖素與glp-1共促效劑
|
|
UA116553C2
(uk)
|
2012-12-21 |
2018-04-10 |
Санофі |
Пептидна сполука - агоніст рецептора glp-1 i glp
|
|
CN103908657A
(zh)
|
2012-12-31 |
2014-07-09 |
复旦大学附属华山医院 |
胰升糖素样肽-1类似物在制备眼科疾病药物中的用途
|
|
BR112015023071A2
(pt)
|
2013-03-14 |
2017-07-18 |
Univ Indiana Res & Tech Corp |
conjugados de insulina-incretina
|
|
WO2014140222A1
(en)
|
2013-03-14 |
2014-09-18 |
Medimmune Limited |
Pegylated glucagon and glp-1 co-agonists for the treatment of obesity
|
|
JP2016521253A
(ja)
|
2013-03-15 |
2016-07-21 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
持続性作用を有するプロドラッグ
|
|
SI2986313T1
(sl)
|
2013-04-18 |
2019-09-30 |
Novo Nordisk A/S |
Stabilni koagonisti GLP-1 / glukagonskega receptorja z dolgotrajnim učinkom za medicinsko uporabo
|
|
JP2014227368A
(ja)
|
2013-05-21 |
2014-12-08 |
国立大学法人帯広畜産大学 |
糖尿病および高血糖状態の処置のためのグルカゴンアナログ
|
|
CN103304660B
(zh)
|
2013-07-12 |
2016-08-10 |
上海昂博生物技术有限公司 |
一种利拉鲁肽的合成方法
|
|
CN103405753B
(zh)
|
2013-08-13 |
2016-05-11 |
上海仁会生物制药股份有限公司 |
稳定的促胰岛素分泌肽水针药物组合物
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
SG11201602965WA
(en)
|
2013-10-17 |
2016-05-30 |
Zealand Pharma As |
Acylated glucagon analogues
|
|
CA2929107C
(en)
|
2013-11-06 |
2023-09-26 |
Zealand Pharma A/S |
Glucagon-glp-1-gip triple agonist compounds
|
|
WO2015086730A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
TW201609795A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
|
|
TW201609797A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重ｇｌｐ－１／升糖素受體促效劑
|
|
WO2015086731A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists
|
|
TW201609799A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重ｇｌｐ－１／ｇｉｐ受體促效劑
|
|
EP3080151A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Exendin-4 peptide analogues
|
|
CN103665148B
(zh)
|
2013-12-17 |
2016-05-11 |
中国药科大学 |
一种可口服给药的降糖多肽及其制法和用途
|
|
CN103980358B
(zh)
|
2014-01-03 |
2016-08-31 |
杭州阿诺生物医药科技股份有限公司 |
一种制备利拉鲁肽的方法
|
|
MX2016008978A
(es)
|
2014-01-09 |
2016-10-04 |
Sanofi Sa |
Formulaciones farmaceuticas de analogos de insulina y/o derivados de insulina estabilizadas y que estan libres de glicerol.
|
|
US9839692B2
(en)
|
2014-01-09 |
2017-12-12 |
Sanofi |
Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CN106519015B
(zh)
|
2014-09-23 |
2020-04-17 |
深圳市图微安创科技开发有限公司 |
胃泌酸调节素类似物
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|