UA97816C2 - Compounds modulating c-kit and/or c-fms activity and use thereof - Google Patents
Compounds modulating c-kit and/or c-fms activity and use thereofInfo
- Publication number
- UA97816C2 UA97816C2 UAA200905046A UAA200905046A UA97816C2 UA 97816 C2 UA97816 C2 UA 97816C2 UA A200905046 A UAA200905046 A UA A200905046A UA A200905046 A UAA200905046 A UA A200905046A UA 97816 C2 UA97816 C2 UA 97816C2
- Authority
- UA
- Ukraine
- Prior art keywords
- kit
- fms
- compounds modulating
- fms activity
- conditions
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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Abstract
Получены соединения, которые имеют активность относительно рецептора тирозинкиназы c-kit и c-fms. Также описаны композиции, которые используются для лечения c-kit-опосредованного заболевания или состояния и c-fms-опосредованного заболевания или состояния, и их применение.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86074906P | 2006-11-22 | 2006-11-22 | |
PCT/US2007/085289 WO2008064255A2 (en) | 2006-11-22 | 2007-11-20 | Compounds modulating c-fms and/or c-kit activity and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
UA97816C2 true UA97816C2 (en) | 2012-03-26 |
Family
ID=39322825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200905046A UA97816C2 (en) | 2006-11-22 | 2007-11-20 | Compounds modulating c-kit and/or c-fms activity and use thereof |
Country Status (35)
Country | Link |
---|---|
US (8) | US7893075B2 (ru) |
EP (1) | EP2086972B1 (ru) |
JP (4) | JP2010510321A (ru) |
KR (1) | KR101506044B1 (ru) |
CN (2) | CN101605787B (ru) |
AR (1) | AR063878A1 (ru) |
AU (1) | AU2007323644B2 (ru) |
BR (1) | BRPI0721137B8 (ru) |
CA (1) | CA2670362C (ru) |
CL (1) | CL2007003326A1 (ru) |
CO (1) | CO6180438A2 (ru) |
CR (1) | CR10817A (ru) |
DK (1) | DK2086972T3 (ru) |
EC (1) | ECSP099357A (ru) |
ES (1) | ES2447779T3 (ru) |
GT (1) | GT200700101A (ru) |
HK (1) | HK1133649A1 (ru) |
IL (1) | IL198624A (ru) |
MX (1) | MX2009005428A (ru) |
MY (1) | MY158447A (ru) |
NI (1) | NI200900093A (ru) |
NO (1) | NO342175B1 (ru) |
NZ (1) | NZ577011A (ru) |
PE (1) | PE20081226A1 (ru) |
PL (1) | PL2086972T3 (ru) |
PT (1) | PT2086972E (ru) |
RU (1) | RU2452738C2 (ru) |
SG (1) | SG176511A1 (ru) |
SI (1) | SI2086972T1 (ru) |
SV (1) | SV2007002813A (ru) |
TW (1) | TWI432431B (ru) |
UA (1) | UA97816C2 (ru) |
UY (1) | UY30732A1 (ru) |
WO (3) | WO2008063888A2 (ru) |
ZA (1) | ZA200903458B (ru) |
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WO2008063888A2 (en) * | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
PE20081581A1 (es) * | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
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