UA80819C2 - Phosphonate analogs of compounds inhibiting hiv proteases, pharmaceutical composition on their basis and their use - Google Patents

Phosphonate analogs of compounds inhibiting hiv proteases, pharmaceutical composition on their basis and their use Download PDF

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Publication number
UA80819C2
UA80819C2 UA20041109372A UA20041109372A UA80819C2 UA 80819 C2 UA80819 C2 UA 80819C2 UA 20041109372 A UA20041109372 A UA 20041109372A UA 20041109372 A UA20041109372 A UA 20041109372A UA 80819 C2 UA80819 C2 UA 80819C2
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Ukraine
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evil
eii
hall
zaz
aia
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UA20041109372A
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English (en)
Ukrainian (uk)
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Xiaowu Chen
Maria Fardis
William A Lee
Hongtao Liu
Matthew A Williams
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Gilead Sciences Inc
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Publication of UA80819C2 publication Critical patent/UA80819C2/uk

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
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    • C07D239/72—Quinazolines; Hydrogenated quinazolines
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