TWI365747B - Anti-ctla-4 antibody compositions - Google Patents

Anti-ctla-4 antibody compositions

Info

Publication number
TWI365747B
TWI365747B TW095107021A TW95107021A TWI365747B TW I365747 B TWI365747 B TW I365747B TW 095107021 A TW095107021 A TW 095107021A TW 95107021 A TW95107021 A TW 95107021A TW I365747 B TWI365747 B TW I365747B
Authority
TW
Taiwan
Prior art keywords
ctla
antibody compositions
antibody
compositions
Prior art date
Application number
TW095107021A
Other languages
English (en)
Other versions
TW200700081A (en
Inventor
Justin Donald Abate
Tapan Kanti Das
Carrie Marie Elliott
Kevin Wamiti Muthurania
Sandeep Nema
Satish Kumar Singh
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of TW200700081A publication Critical patent/TW200700081A/zh
Application granted granted Critical
Publication of TWI365747B publication Critical patent/TWI365747B/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243Colony Stimulating Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K9/08Solutions
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
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TW095107021A 2005-03-08 2006-03-02 Anti-ctla-4 antibody compositions TWI365747B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65976605P 2005-03-08 2005-03-08
US72816505P 2005-10-19 2005-10-19
US75271205P 2005-12-20 2005-12-20
US76245606P 2006-01-26 2006-01-26

Publications (2)

Publication Number Publication Date
TW200700081A TW200700081A (en) 2007-01-01
TWI365747B true TWI365747B (en) 2012-06-11

Family

ID=36646098

Family Applications (4)

Application Number Title Priority Date Filing Date
TW095107087A TW200642694A (en) 2005-03-08 2006-03-02 Anti-M-CSF antibody compositions
TW095107021A TWI365747B (en) 2005-03-08 2006-03-02 Anti-ctla-4 antibody compositions
TW095107035A TW200719913A (en) 2005-03-08 2006-03-02 Anti-madcam antibody compositions
TW095107092A TW200709817A (en) 2005-03-08 2006-03-03 Platform antibody compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TW095107087A TW200642694A (en) 2005-03-08 2006-03-02 Anti-M-CSF antibody compositions

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW095107035A TW200719913A (en) 2005-03-08 2006-03-02 Anti-madcam antibody compositions
TW095107092A TW200709817A (en) 2005-03-08 2006-03-03 Platform antibody compositions

Country Status (25)

Country Link
US (5) US20080248047A1 (zh)
EP (6) EP1868646A2 (zh)
JP (7) JP2006249084A (zh)
KR (2) KR100996801B1 (zh)
CN (1) CN103861102A (zh)
AR (4) AR053026A1 (zh)
AU (2) AU2006220829C1 (zh)
BR (1) BRPI0608855A2 (zh)
CA (4) CA2600836A1 (zh)
CY (1) CY1121254T1 (zh)
DK (2) DK2620450T3 (zh)
ES (2) ES2569409T3 (zh)
FI (1) FIC20230027I1 (zh)
FR (1) FR23C1029I1 (zh)
HK (1) HK1125297A1 (zh)
HU (3) HUE028410T2 (zh)
IL (3) IL185380A0 (zh)
LT (2) LT2620450T (zh)
MX (2) MX2007010970A (zh)
NZ (2) NZ560844A (zh)
PL (1) PL2620450T3 (zh)
PT (1) PT2620450T (zh)
SI (2) SI2620450T1 (zh)
TW (4) TW200642694A (zh)
WO (4) WO2006096461A2 (zh)

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PT2177537E (pt) 2004-01-09 2011-12-13 Pfizer Anticorpos contra madcam
WO2006096461A2 (en) 2005-03-08 2006-09-14 Pharmacia & Upjohn Company Llc Composition comprising an antibody against macrophage colony-stimulating factor (m-csf) and a chelating agent
WO2007024743A2 (en) * 2005-08-19 2007-03-01 Centocor, Inc. Proteolysis resistant antibody preparations
CL2007002567A1 (es) 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
DK2486941T3 (en) 2006-10-02 2017-06-26 Squibb & Sons Llc HUMAN ANTIBODIES BINDING CXCR4 AND APPLICATIONS THEREOF
AU2012200284B2 (en) * 2006-10-06 2014-03-06 Amgen Inc. Stable Antibody Formulations
WO2008045373A2 (en) * 2006-10-06 2008-04-17 Amgen Inc. Stable antibody formulations
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
AU2007309616B2 (en) * 2006-10-20 2011-10-06 Amgen Inc. Stable polypeptide formulations
EP2078039B1 (en) * 2006-11-01 2017-09-13 Biogen MA Inc. Method of isolating biomacromolecules using low ph and divalent cations
US20100189721A1 (en) * 2007-07-06 2010-07-29 Smithkline Beecham Corporation Antibody formulations
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