BRPI0608815A8 - Composições de anticorpo anti-ctla-4 - Google Patents

Composições de anticorpo anti-ctla-4

Info

Publication number
BRPI0608815A8
BRPI0608815A8 BRPI0608815A BRPI0608815A BRPI0608815A8 BR PI0608815 A8 BRPI0608815 A8 BR PI0608815A8 BR PI0608815 A BRPI0608815 A BR PI0608815A BR PI0608815 A BRPI0608815 A BR PI0608815A BR PI0608815 A8 BRPI0608815 A8 BR PI0608815A8
Authority
BR
Brazil
Prior art keywords
ctla
antibody compositions
conditions
novel
medicaments
Prior art date
Application number
BRPI0608815A
Other languages
English (en)
Inventor
Donald Abate Justin
Kanti Das Tapan
Marie Elliot Carrie
Wamiti Muthurnia Kevin
Nema Sandeep
Kumar Singh Satish
Original Assignee
Pharmacia & Upjohn Co Llc
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc, Pfizer Prod Inc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0608815A2 publication Critical patent/BRPI0608815A2/pt
Publication of BRPI0608815A8 publication Critical patent/BRPI0608815A8/pt
Publication of BRPI0608815B1 publication Critical patent/BRPI0608815B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243Colony Stimulating Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • CCHEMISTRY; METALLURGY
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Abstract

COMPOSIÇÕES DE ANTICORPO ANTI-CTLA-4 A presente invenção proporciona novas composições de anticorpos anti-CTLA-4 compreendendo um agente quelante. Também é proporcionado o uso das novas composições de anticorpos cTLA-4 para a preparação de medicamentos para o tratamento de doenças e condições, incluindo várias condições neoplásicas.
BRPI0608815-5A 2005-03-08 2006-03-02 Composições de anticorpo anti-ctla-4 BRPI0608815B1 (pt)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US65976605P 2005-03-08 2005-03-08
US60/659.766 2005-03-08
US60/659,766 2005-03-08
US72816505P 2005-10-19 2005-10-19
US60/728,165 2005-10-19
US60/728.165 2005-10-19
US75271205P 2005-12-20 2005-12-20
US60/752.712 2005-12-20
US60/752,712 2005-12-20
US76245606P 2006-01-26 2006-01-26
US60/762,456 2006-01-26
US60/762.456 2006-01-26
PCT/US2006/007555 WO2006096491A2 (en) 2005-03-08 2006-03-02 Anti-ctla-4 antibody compositions

Publications (3)

Publication Number Publication Date
BRPI0608815A2 BRPI0608815A2 (pt) 2010-01-26
BRPI0608815A8 true BRPI0608815A8 (pt) 2017-03-21
BRPI0608815B1 BRPI0608815B1 (pt) 2021-10-13

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Also Published As

Publication number Publication date
PT2620450T (pt) 2018-12-17
NZ560844A (en) 2008-08-29
SI2620450T1 (sl) 2019-01-31
EP1865986A2 (en) 2007-12-19
HUE028410T2 (en) 2016-12-28
WO2006096488A2 (en) 2006-09-14
JP2006249083A (ja) 2006-09-21
PL2620450T3 (pl) 2019-05-31
WO2006096461A3 (en) 2006-12-21
CA2600434A1 (en) 2006-09-14
CA2600434C (en) 2017-09-19
DK1865986T3 (en) 2016-04-11
EP1865986B1 (en) 2016-02-17
WO2006096488A3 (en) 2006-11-30
AU2006220829B2 (en) 2011-10-13
IL185380A0 (en) 2008-02-09
WO2006096491A3 (en) 2007-03-29
AR053553A1 (es) 2007-05-09
AR062247A1 (es) 2008-10-29
JP2006249084A (ja) 2006-09-21
TW200642694A (en) 2006-12-16
KR100996801B1 (ko) 2010-11-25
WO2006096490A3 (en) 2006-12-28
HUS2300026I1 (hu) 2023-09-28
JP2012167120A (ja) 2012-09-06
JP2006249085A (ja) 2006-09-21
BRPI0608815A2 (pt) 2010-01-26
EP1868646A2 (en) 2007-12-26
HK1125297A1 (en) 2009-08-07
AU2006220828A1 (en) 2006-09-14
CA2600836A1 (en) 2006-09-14
TWI365747B (en) 2012-06-11
JP2013032387A (ja) 2013-02-14
MX2007010970A (es) 2007-09-19
EP2620450A3 (en) 2014-01-08
US20090110681A1 (en) 2009-04-30
JP5670004B2 (ja) 2015-02-18
DK2620450T3 (en) 2019-02-04
MX2007010971A (es) 2007-09-19
TW200709817A (en) 2007-03-16
AR054233A1 (es) 2007-06-13
EP2620450A2 (en) 2013-07-31
JP2006249081A (ja) 2006-09-21
US9487581B2 (en) 2016-11-08
EP2620450B1 (en) 2018-11-07
KR20070100922A (ko) 2007-10-12
ES2707284T3 (es) 2019-04-03
KR100989280B1 (ko) 2010-10-20
WO2006096490A2 (en) 2006-09-14
CY1121254T1 (el) 2020-05-29
US20090130119A1 (en) 2009-05-21
SI1865986T1 (sl) 2016-05-31
FR23C1029I1 (fr) 2023-10-06
FIC20230027I1 (fi) 2023-08-02
BRPI0608855A2 (pt) 2010-02-02
IL185483A (en) 2013-04-30
NZ561137A (en) 2011-09-30
AU2006220829A1 (en) 2006-09-14
ES2569409T3 (es) 2016-05-10
JP6212509B2 (ja) 2017-10-11
EP1858552A2 (en) 2007-11-28
CA2600588A1 (en) 2006-09-14
AU2006220829C1 (en) 2024-02-01
HUE041802T2 (hu) 2019-05-28
TW200719913A (en) 2007-06-01
WO2006096491A2 (en) 2006-09-14
CA2600608A1 (en) 2006-09-14
JP2015110656A (ja) 2015-06-18
LT2620450T (lt) 2019-02-11
US20080248047A1 (en) 2008-10-09
WO2006096491A9 (en) 2008-04-03
TW200700081A (en) 2007-01-01
US20090238820A1 (en) 2009-09-24
WO2006096461A2 (en) 2006-09-14
LTPA2023522I1 (pt) 2023-09-11
WO2006096490A8 (en) 2007-02-01
IL225435A0 (en) 2013-06-27
US20110027262A1 (en) 2011-02-03
IL185483A0 (en) 2008-01-06
AR053026A1 (es) 2007-04-18
EP1871806A2 (en) 2008-01-02
CN103861102A (zh) 2014-06-18
KR20070100848A (ko) 2007-10-11
EP2311491A1 (en) 2011-04-20

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