BRPI0608815A8 - Composições de anticorpo anti-ctla-4 - Google Patents
Composições de anticorpo anti-ctla-4Info
- Publication number
- BRPI0608815A8 BRPI0608815A8 BRPI0608815A BRPI0608815A BRPI0608815A8 BR PI0608815 A8 BRPI0608815 A8 BR PI0608815A8 BR PI0608815 A BRPI0608815 A BR PI0608815A BR PI0608815 A BRPI0608815 A BR PI0608815A BR PI0608815 A8 BRPI0608815 A8 BR PI0608815A8
- Authority
- BR
- Brazil
- Prior art keywords
- ctla
- antibody compositions
- conditions
- novel
- medicaments
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229940045513 CTLA4 antagonist Drugs 0.000 title abstract 3
- 239000002738 chelating agent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- C—CHEMISTRY; METALLURGY
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Abstract
COMPOSIÇÕES DE ANTICORPO ANTI-CTLA-4 A presente invenção proporciona novas composições de anticorpos anti-CTLA-4 compreendendo um agente quelante. Também é proporcionado o uso das novas composições de anticorpos cTLA-4 para a preparação de medicamentos para o tratamento de doenças e condições, incluindo várias condições neoplásicas.
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65976605P | 2005-03-08 | 2005-03-08 | |
US60/659.766 | 2005-03-08 | ||
US60/659,766 | 2005-03-08 | ||
US72816505P | 2005-10-19 | 2005-10-19 | |
US60/728,165 | 2005-10-19 | ||
US60/728.165 | 2005-10-19 | ||
US75271205P | 2005-12-20 | 2005-12-20 | |
US60/752.712 | 2005-12-20 | ||
US60/752,712 | 2005-12-20 | ||
US76245606P | 2006-01-26 | 2006-01-26 | |
US60/762,456 | 2006-01-26 | ||
US60/762.456 | 2006-01-26 | ||
PCT/US2006/007555 WO2006096491A2 (en) | 2005-03-08 | 2006-03-02 | Anti-ctla-4 antibody compositions |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0608815A2 BRPI0608815A2 (pt) | 2010-01-26 |
BRPI0608815A8 true BRPI0608815A8 (pt) | 2017-03-21 |
BRPI0608815B1 BRPI0608815B1 (pt) | 2021-10-13 |
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