|
US2088897A
(en)
*
|
1935-03-25 |
1937-08-03 |
Goss Printing Press Co Ltd |
Printing press
|
|
US2557381A
(en)
*
|
1946-08-09 |
1951-06-19 |
William C Huebner |
Multiple unit printing press
|
|
DE2234089C3
(de)
*
|
1972-07-08 |
1975-01-23 |
Automatic Druckmaschinenfabrik Dr. W. Hinniger U. Soehne, 1000 Berlin |
Offset-Rollen-Rotationsdruckmaschine
|
|
GB1581233A
(en)
*
|
1976-06-02 |
1980-12-10 |
Drg Uk Ltd |
Printing press
|
|
US4201706A
(en)
|
1978-09-22 |
1980-05-06 |
Burton, Parsons & Company, Inc. |
Treatment of corneal edema
|
|
US4454151A
(en)
|
1982-03-22 |
1984-06-12 |
Syntex (U.S.A.) Inc. |
Use of pyrrolo pyrroles in treatment of ophthalmic diseases
|
|
US4515722A
(en)
*
|
1982-03-30 |
1985-05-07 |
Merck & Co., Inc. |
Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
|
|
US4474806A
(en)
|
1982-05-10 |
1984-10-02 |
Merck & Co., Inc. |
Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents
|
|
IT1164225B
(it)
|
1983-05-13 |
1987-04-08 |
Anic Spa |
Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
|
|
DE3405663A1
(de)
|
1984-02-17 |
1985-08-22 |
Merck Patent Gmbh, 6100 Darmstadt |
Verfahren zur herstellung von scyllo-inosit
|
|
US5330979A
(en)
|
1984-10-23 |
1994-07-19 |
Perstorp Ab |
Method of treating renal disorders with inositoltriphosphate
|
|
US4735902A
(en)
*
|
1984-10-23 |
1988-04-05 |
Matti Siren |
Stabilized composition containing inositoltriphosphate
|
|
US5128332A
(en)
*
|
1984-10-23 |
1992-07-07 |
Perstorp Ab |
Method of treating cardiovascular diseases using inositoltrisphosphate
|
|
US5407924A
(en)
|
1984-10-23 |
1995-04-18 |
Perstorp Ab |
Method of treating pain using inositol triphosphate
|
|
SE465951B
(sv)
*
|
1984-10-23 |
1991-11-25 |
Perstorp Ab |
Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
|
|
SE465305B
(sv)
*
|
1986-04-16 |
1991-08-26 |
Perstorp Ab |
Anvaendning av inositolfosfat foer framstaellning av ett laekemedel
|
|
US5545632A
(en)
|
1984-10-23 |
1996-08-13 |
Perstorp Ab |
Method of treating retroviral disease
|
|
US5023248A
(en)
*
|
1984-10-23 |
1991-06-11 |
Perstorp Ab |
Method of treating diabetes with inositol triphosphate
|
|
IL74497A
(en)
|
1985-03-05 |
1990-02-09 |
Proterra Ag |
Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
|
|
DE3610107A1
(de)
*
|
1986-03-26 |
1987-10-08 |
Voith Gmbh J M |
Stellvorrichtung zum verstellen einer walze
|
|
US5057507A
(en)
*
|
1986-04-16 |
1991-10-15 |
Perstorp Ab |
Method of alleviating bone damage with inositoltriphosphate
|
|
US5135923A
(en)
|
1986-04-16 |
1992-08-04 |
Perstorp Ab |
Method of treating cardiovascular diseases
|
|
US4758420A
(en)
|
1986-07-14 |
1988-07-19 |
The Dow Chemical Company |
Solvent extraction of polychlorinated organic compounds from porous materials
|
|
US4952396A
(en)
*
|
1986-11-19 |
1990-08-28 |
Linus Pauling Institute Of Science & Medicine |
Method of using phytic acid for inhibiting tumor growth
|
|
US4847082A
(en)
*
|
1987-01-21 |
1989-07-11 |
Robert Sabin |
Method of treatment of Alzheimer's disease using phytic acid
|
|
US4758430A
(en)
*
|
1987-01-21 |
1988-07-19 |
Robert Sabin |
Method of treatment of Alzheimer's disease using phytic acid
|
|
HU201906B
(en)
|
1987-03-04 |
1991-01-28 |
Sandoz Ag |
Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
|
|
JPH067158Y2
(ja)
|
1987-03-18 |
1994-02-23 |
株式会社藤井合金製作所 |
配管端末の防水構造
|
|
FI95572C
(fi)
*
|
1987-06-22 |
1996-02-26 |
Eisai Co Ltd |
Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
|
|
DE3808142A1
(de)
*
|
1988-03-11 |
1989-09-21 |
Goebel Gmbh Maschf |
Lagereinrichtung
|
|
DE3814752C1
(enExample)
*
|
1988-04-30 |
1989-08-31 |
J.M. Voith Gmbh, 7920 Heidenheim, De |
|
|
US5334618A
(en)
*
|
1991-04-04 |
1994-08-02 |
The Children's Medical Center Corporation |
Method of preventing NMDA receptor-mediated neuronal damage
|
|
JPH03102492A
(ja)
|
1989-06-12 |
1991-04-26 |
Mitsui Eng & Shipbuild Co Ltd |
自動販売機のデータ送信システムおよび複合機能型自動販売機
|
|
SE8904355D0
(sv)
|
1989-12-21 |
1989-12-21 |
Perstorp Ab |
Medicament
|
|
US5111814A
(en)
*
|
1990-07-06 |
1992-05-12 |
Thomas Jefferson University |
Laryngeal pacemaker
|
|
US5217959A
(en)
*
|
1990-09-06 |
1993-06-08 |
Robert Sabin |
Method of treating multiple sclerosis with phytic acid
|
|
JP2984043B2
(ja)
|
1990-09-18 |
1999-11-29 |
旭化成工業株式会社 |
ミオ・イノシトールデヒドロゲナーゼおよびその製造法
|
|
US5112814A
(en)
*
|
1990-10-24 |
1992-05-12 |
Robert Sabin |
Method of treatment of Parkinson's disease using phytic acid
|
|
SE9102068L
(sv)
*
|
1991-07-03 |
1993-01-04 |
Perstorp Ab |
Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav
|
|
JPH05192163A
(ja)
|
1991-09-30 |
1993-08-03 |
Suntory Ltd |
イノシトールデヒドロゲナーゼ遺伝子
|
|
WO1993012093A1
(en)
|
1991-12-18 |
1993-06-24 |
Schering Corporation |
Imidazolyl-alkyl-piperazine and -diazepine derivatives as histamine h3 agonists/antagonists
|
|
SE469260B
(sv)
*
|
1992-02-25 |
1993-06-14 |
Perstorp Ab |
En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat
|
|
JP3251976B2
(ja)
|
1992-06-23 |
2002-01-28 |
旭化成株式会社 |
ミオ・イノシトールデヒドロゲナーゼを生産する実質上純粋な微生物
|
|
US5351616A
(en)
*
|
1992-08-13 |
1994-10-04 |
Man Roland Druckmaschinen Ag |
Rotary web printing machine, particularly for printing on thick or carton-type stock webs with replaceable plate cylinders
|
|
DE4229494A1
(de)
|
1992-09-04 |
1994-03-10 |
Basotherm Gmbh |
Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks
|
|
NZ256610A
(en)
*
|
1992-10-05 |
1997-03-24 |
Virginia Tech Intell Prop |
Synthesis of epoxydiol intermediates in the preparation of inositols and inosose; epoxydiols
|
|
US5643562A
(en)
*
|
1993-03-29 |
1997-07-01 |
Queen's University Of Kingston |
Method for treating amyloidosis
|
|
US5972328A
(en)
*
|
1993-03-29 |
1999-10-26 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
US5840294A
(en)
*
|
1993-03-29 |
1998-11-24 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
DK0619369T3
(da)
*
|
1993-04-05 |
2003-10-06 |
Aveve Nv |
Phytathydrolyse og enzymsammensætning til hydrolyse af phytat
|
|
ATE176779T1
(de)
*
|
1993-08-11 |
1999-03-15 |
Hokko Chem Ind Co |
Verfahren zur herstellung von d-chiro inositol
|
|
US5412080A
(en)
|
1993-08-25 |
1995-05-02 |
President And Fellow Of Harvard College |
Enterobactin compounds
|
|
SE502574C2
(sv)
*
|
1994-01-25 |
1995-11-13 |
Perstorp Ab |
En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat
|
|
DE4408025A1
(de)
*
|
1994-03-10 |
1995-09-14 |
Koenig & Bauer Ag |
Druckwerk für eine Mehrfarbenrollenrotationsdruckmaschine
|
|
DE4430693B4
(de)
*
|
1994-08-30 |
2005-12-22 |
Man Roland Druckmaschinen Ag |
Antriebe für eine Rollenrotations-Offsetdruckmaschine
|
|
US5550166A
(en)
|
1995-03-17 |
1996-08-27 |
Ostlund; Richard E. |
Pinitol and derivatives thereof for the treatment of metabolic disorders
|
|
US5858326A
(en)
*
|
1995-06-06 |
1999-01-12 |
Neurochem, Inc. |
Methods of increasing amyloid deposition
|
|
US6221645B1
(en)
|
1995-06-07 |
2001-04-24 |
Elan Pharmaceuticals, Inc. |
β-secretase antibody
|
|
JP3630344B2
(ja)
|
1995-11-17 |
2005-03-16 |
北興化学工業株式会社 |
イノシトール立体異性体の製造方法
|
|
AU1153097A
(en)
|
1996-06-07 |
1998-01-05 |
Eisai Co. Ltd. |
Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production
|
|
TW513409B
(en)
|
1996-06-07 |
2002-12-11 |
Eisai Co Ltd |
Polymorphs of donepezil hydrochloride
|
|
US6232486B1
(en)
*
|
1996-06-11 |
2001-05-15 |
Nutrimed Biotech |
Molecular probes and modulators for PI-PLC and PI 3-kinase
|
|
TW506836B
(en)
|
1996-06-14 |
2002-10-21 |
Janssen Pharmaceutica Nv |
Fast-dissolving galanthamine hydrobromide tablet
|
|
US5977078A
(en)
*
|
1996-09-20 |
1999-11-02 |
The Regents Of The Univesity Of California |
Inositol polyphosphate derivatives and methods of using same
|
|
US5880099A
(en)
*
|
1996-09-20 |
1999-03-09 |
The Regents Of The University Of California |
Inositol polyphosphates and methods of using same
|
|
US6218506B1
(en)
|
1997-02-05 |
2001-04-17 |
Northwestern University |
Amyloid β protein (globular assembly and uses thereof)
|
|
US20030068316A1
(en)
|
1997-02-05 |
2003-04-10 |
Klein William L. |
Anti-ADDL antibodies and uses thereof
|
|
DK0966277T3
(da)
|
1997-03-10 |
2006-03-27 |
Univ Loma Linda Med |
Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom
|
|
US5998485A
(en)
*
|
1997-06-16 |
1999-12-07 |
Cedars-Sinai Medical Center |
Method for modulating immune response with inositol
|
|
US6153603A
(en)
*
|
1997-06-27 |
2000-11-28 |
Perstorp Ab |
Method of treating angiogenesis in tumor tissue
|
|
GB9801899D0
(en)
|
1998-01-29 |
1998-03-25 |
Univ London |
Neurotrophic properties of ipgs analogues
|
|
DE19805898C2
(de)
*
|
1998-02-13 |
2003-09-18 |
Roland Man Druckmasch |
Druckwerk für eine Rollenrotationsdruckmaschine
|
|
US6720190B1
(en)
|
1998-03-27 |
2004-04-13 |
Ole Hindsgaul |
Methods for screening compound libraries
|
|
US5981168A
(en)
|
1998-05-15 |
1999-11-09 |
The University Of British Columbia |
Method and composition for modulating amyloidosis
|
|
US6227110B1
(en)
*
|
1998-06-23 |
2001-05-08 |
Heidelberger Druckmaschinen Ag |
Wet printing press with throw-off mechanism
|
|
US6310073B1
(en)
*
|
1998-07-28 |
2001-10-30 |
Queen's University At Kingston |
Methods and compositions to treat glycosaminoglycan-associated molecular interactions
|
|
AUPP589398A0
(en)
|
1998-09-14 |
1998-10-08 |
Walter And Eliza Hall Institute Of Medical Research, The |
Immunogenic compositions and uses thereof
|
|
CA2343004A1
(en)
|
1998-09-24 |
2000-03-30 |
Pharmacia & Upjohn Company |
Alzheimer's disease secretase
|
|
AUPP675898A0
(en)
|
1998-10-27 |
1998-11-19 |
Walter And Eliza Hall Institute Of Medical Research, The |
A method of activating t cells and agents useful for same
|
|
US6221856B1
(en)
|
1999-02-03 |
2001-04-24 |
Inologic, Inc. |
Inositol derivatives for inhibiting superoxide anion production
|
|
GB2389182B
(en)
|
1999-02-10 |
2004-02-04 |
Elan Pharm Inc |
Method of purifying b-secretase
|
|
NZ534876A
(en)
|
1999-02-10 |
2006-02-24 |
Elan Pharm Inc |
Human beta-secretase enzyme, inhibitors and their compositions and uses
|
|
IL144781A0
(en)
|
1999-02-26 |
2002-06-30 |
Merck & Co Inc |
Novel sulfonamide compounds and uses thereof
|
|
US6818430B1
(en)
*
|
1999-06-07 |
2004-11-16 |
Hokko Chemical Industry Co., Ltd. |
Process for producing L-epi-2-inosose and novel process for producing epi-inositol
|
|
US6864240B1
(en)
|
1999-06-15 |
2005-03-08 |
Elan Pharmaceuticals, Inc. |
Dipeptide inhibitors of β-secretase
|
|
JP2003502342A
(ja)
|
1999-06-15 |
2003-01-21 |
エラン ファーマスーティカルズ インコーポレイテッド |
ベータ−セクレターゼのスタチン誘導テトラペプチド阻害剤
|
|
WO2001003680A2
(en)
|
1999-07-09 |
2001-01-18 |
Isis Innovation Limited |
Compounds for inhibiting diseases and preparing cells for transplantation
|
|
DE19937805A1
(de)
*
|
1999-08-10 |
2001-02-15 |
Roland Man Druckmasch |
Druckwerk
|
|
DE19937803A1
(de)
*
|
1999-08-10 |
2001-02-15 |
Roland Man Druckmasch |
Druckwerk
|
|
DE19937796B4
(de)
*
|
1999-08-10 |
2007-03-22 |
Man Roland Druckmaschinen Ag |
Druckwerk
|
|
US20020052311A1
(en)
*
|
1999-09-03 |
2002-05-02 |
Beka Solomon |
Methods and compostions for the treatment and/or diagnosis of neurological diseases and disorders
|
|
US6329256B1
(en)
*
|
1999-09-24 |
2001-12-11 |
Advanced Micro Devices, Inc. |
Self-aligned damascene gate formation with low gate resistance
|
|
JP2001163810A
(ja)
|
1999-09-30 |
2001-06-19 |
Microbial Chem Res Found |
1d−キロ−イノシトールの新規合成方法および中間体
|
|
JP2003511094A
(ja)
|
1999-10-18 |
2003-03-25 |
マッスルテク リサーチ アンド ディヴェロプメント インコーポレーション |
無脂肪体重及び体力を増強するための食物補充物質
|
|
US7728043B2
(en)
|
1999-10-22 |
2010-06-01 |
Kim Darrick S H L |
Methods for treatment of beta-amyloid protein-induced ocular disease
|
|
CA2388750A1
(en)
|
1999-11-09 |
2001-05-17 |
James Edmund Audia |
.beta.-aminoacid compounds useful for inhibiting .beta.-amyloid peptide release and/or its synthesis
|
|
WO2001034571A1
(en)
|
1999-11-09 |
2001-05-17 |
Eli Lilly And Company |
β-AMINOACID COMPOUNDS USEFUL FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS
|
|
DE19963944C1
(de)
*
|
1999-12-31 |
2001-06-13 |
Koenig & Bauer Ag |
Verfahren zum Einstellen einer Walze einer Druckmaschine
|
|
EP1254108A1
(en)
|
2000-01-24 |
2002-11-06 |
MERCK SHARP & DOHME LTD. |
Gamma-secretase inhibitors
|
|
DE10008215B4
(de)
*
|
2000-02-23 |
2013-03-28 |
Manroland Web Systems Gmbh |
Druckwerk für eine Rotationsdruckmaschine mit Kreuzschlitten
|
|
GB0005251D0
(en)
|
2000-03-03 |
2000-04-26 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
US20030144255A1
(en)
*
|
2000-03-06 |
2003-07-31 |
Bain Allen I |
Compositions for prevention and treatment of dementia
|
|
JP2003528076A
(ja)
|
2000-03-20 |
2003-09-24 |
メルク シャープ エンド ドーム リミテッド |
スルホンアミド置換架橋ビシクロアルキル誘導体
|
|
ATE343562T1
(de)
|
2000-03-23 |
2006-11-15 |
Elan Pharm Inc |
Verbindungen und verfahren zur behandlung der alzheimerschen krankheit
|
|
GB0008710D0
(en)
|
2000-04-07 |
2000-05-31 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
CA2406383A1
(en)
|
2000-04-13 |
2001-10-25 |
Mayo Foundation For Medical Education And Research |
A.beta.42 lowering agents
|
|
US6716826B2
(en)
|
2000-05-12 |
2004-04-06 |
Rodaris Pharmaceuticals Limited |
Compounds and their uses
|
|
US6939857B2
(en)
|
2000-05-12 |
2005-09-06 |
Rodaris Pharmaceuticals Limited |
Compounds and their uses
|
|
US20040110743A1
(en)
|
2000-05-19 |
2004-06-10 |
Masaomi Miyamato |
-Secretase inhibitors
|
|
GB0015627D0
(en)
|
2000-06-26 |
2000-08-16 |
Rademacher Group Limited |
Phosphoglycan messengers and their medical uses
|
|
US6846813B2
(en)
|
2000-06-30 |
2005-01-25 |
Pharmacia & Upjohn Company |
Compounds to treat alzheimer's disease
|
|
PE20020276A1
(es)
|
2000-06-30 |
2002-04-06 |
Elan Pharm Inc |
COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
|
|
EP1299352B1
(en)
|
2000-06-30 |
2005-12-28 |
Elan Pharmaceuticals, Inc. |
Compounds to treat alzheimer's disease
|
|
DE10031955A1
(de)
|
2000-06-30 |
2002-01-17 |
Deutsches Krebsforsch |
Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel
|
|
GB0016681D0
(en)
|
2000-07-06 |
2000-08-23 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
US6559891B1
(en)
*
|
2000-08-15 |
2003-05-06 |
Sony Corporation |
Method and apparatus to generate tri-level HDTV synchronization pulses
|
|
JP3880051B2
(ja)
|
2000-11-02 |
2007-02-14 |
メルク シャープ エンド ドーム リミテッド |
γ−セクレターゼ阻害剤としてのスルファミド
|
|
ATE406371T1
(de)
|
2000-11-02 |
2008-09-15 |
Us Gov Health & Human Serv |
Wirkstoffe für die verminderung von amyloid precursor protein und die behandlung von schwachsinn, und deren verfahren der verwendung
|
|
WO2002055715A1
(fr)
|
2001-01-15 |
2002-07-18 |
Hokko Chemical Industry Co., Ltd. |
Adn codant pour une d-myo-inositol 1-épimérase
|
|
CA2437563C
(en)
|
2001-02-06 |
2010-03-23 |
Qlt Inc. |
Photodynamic therapy of occult age-related macular degeneration
|
|
EP1233021A3
(en)
|
2001-02-20 |
2002-11-20 |
Pfizer Products Inc. |
An inhibitor of Beta amyloid cleavage enzyme
|
|
US20060079533A1
(en)
|
2001-03-23 |
2006-04-13 |
Nieman James A |
Methods of treating alzheimer's disease
|
|
EP1393900B1
(de)
*
|
2001-04-09 |
2014-03-12 |
Koenig & Bauer Aktiengesellschaft |
Druckmaschine
|
|
US20030095958A1
(en)
|
2001-04-27 |
2003-05-22 |
Bhisetti Govinda R. |
Inhibitors of bace
|
|
CA2448084A1
(en)
|
2001-05-22 |
2002-11-28 |
Elan Pharmaceuticals, Inc. |
Aza hydroxylated ethyl amine compounds
|
|
EP1990057A1
(en)
|
2001-05-22 |
2008-11-12 |
Merck & Co., Inc. |
Beta-secretase substrates and uses thereof
|
|
DE60226729D1
(de)
|
2001-06-01 |
2008-07-03 |
Elan Pharm Inc |
Hydroxyalkylaminderivate als beta-secretase-inhibitoren und deren verwendung zur behandlung der alzheimerschen krankheit oder ähnlicher krankheiten
|
|
US6684775B2
(en)
*
|
2001-06-07 |
2004-02-03 |
Heidelberger Druckmaschinen Ag |
Printing unit with roll-away inkers
|
|
US20050130941A1
(en)
|
2001-06-08 |
2005-06-16 |
Heinrich Schostarez |
Methods of treating alzheimer's disease
|
|
US7361688B2
(en)
|
2001-06-11 |
2008-04-22 |
Elan Pharmaceuticals, Inc. |
Substituted aminoalcohols useful in treatment of Alzheimer's disease
|
|
MXPA03011466A
(es)
|
2001-06-12 |
2004-07-01 |
Elan Pharm Inc |
Macrociclos utiles en tratamiento de enfermedades de alzheimer.
|
|
CA2450167A1
(en)
|
2001-06-12 |
2002-12-19 |
Elan Pharmaceuticals, Inc. |
Macrocycles useful in the treatment of alzheimer's disease
|
|
EP1395251A2
(en)
|
2001-06-13 |
2004-03-10 |
Elan Pharmaceuticals, Inc. |
Aminediols as agents for the treatment of alzheimer's disease
|
|
MXPA04000139A
(es)
|
2001-06-25 |
2004-06-03 |
Pharmacia & Up John Company |
Uso de compuestos biciclo para tratar enfermedad de alzheimer.
|
|
JP3981597B2
(ja)
|
2001-06-25 |
2007-09-26 |
北興化学工業株式会社 |
シロ−イノソースの製造法及びシロ−イノシトールの製造法
|
|
US6982264B2
(en)
|
2001-06-27 |
2006-01-03 |
Elan Pharmaceuticals, Inc. |
Substituted alcohols useful in treatment of Alzheimer's disease
|
|
CA2453447A1
(en)
|
2001-07-10 |
2003-01-23 |
Elan Pharmaceuticals, Inc. |
Alpha-hydroxyamide statine derivatives for the treatment of alzheimer's disease
|
|
CA2453451A1
(en)
|
2001-07-10 |
2003-01-23 |
Elan Pharmaceuticals, Inc. |
Aminediols for the treatment of alzheimer's disease
|
|
BR0211118A
(pt)
|
2001-07-10 |
2004-10-26 |
Elan Pharm Inc |
Composto, métodos para o tratamento ou prevenção de doenças e para fabricar um composto, intermediário, e, uso de um composto ou sal
|
|
US20030181531A1
(en)
|
2003-02-11 |
2003-09-25 |
David Sherris |
Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases
|
|
US6599891B2
(en)
|
2001-07-20 |
2003-07-29 |
Qlt Inc. |
Treatment of macular edema
|
|
EP1411944A1
(en)
|
2001-08-03 |
2004-04-28 |
Schering Corporation |
Sulfonamide derivatives as gamma secretase inhibitors
|
|
PL372212A1
(en)
|
2001-08-03 |
2005-07-11 |
Schering Corporation |
Novel gamma secretase inhibitors
|
|
US20040266871A1
(en)
|
2001-08-28 |
2004-12-30 |
Schostarez Heinrich Josef |
Methods for treating alzheimer's disease using quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
|
|
DE10145322A1
(de)
*
|
2001-09-14 |
2003-04-03 |
Ina Schaeffler Kg |
Lageranordnung für Zylinder, Walzen oder Trommeln
|
|
MXPA04002785A
(es)
|
2001-09-24 |
2004-07-29 |
Elan Pharm Inc |
Aminas sustituidas para tratamiento de enfermedad de alzheimer.
|
|
MXPA04003245A
(es)
|
2001-10-04 |
2004-08-11 |
Elan Pharm Inc |
Hidroxipropilaminas.
|
|
WO2003030886A2
(en)
|
2001-10-05 |
2003-04-17 |
Elan Pharmaceuticals, Inc |
Allylamides useful in the treatment of alzheimer's disease
|
|
JP4547152B2
(ja)
|
2001-10-23 |
2010-09-22 |
オクラホマ メディカル リサーチ ファウンデーション |
β−セクレターゼ阻害剤および使用方法
|
|
CA2465316A1
(en)
|
2001-10-29 |
2003-05-08 |
James P. Beck |
Hydroxy substituted amides for the treatment of alzheimer's disease
|
|
EA200400648A1
(ru)
|
2001-11-08 |
2005-04-28 |
Элан Фармасьютикалз, Инк. |
N, n'-замещенные производные 1,3-диамино-2-гидроксипропана
|
|
NZ533158A
(en)
|
2001-11-19 |
2006-09-29 |
Elan Pharm Inc |
3,4-Disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines and piperazines
|
|
MXPA04004903A
(es)
|
2001-11-21 |
2005-06-06 |
Elan Pharm Inc |
Derivados de aminoacido utiles para el tratamiento de la enfermedad de alzheimer.
|
|
WO2003047576A1
(en)
|
2001-12-04 |
2003-06-12 |
Elan Pharmaceuticals, Inc. |
Peptide isosteres containing a heterocycle useful in the treatment of alzheimer's disease
|
|
BR0214736A
(pt)
|
2001-12-06 |
2004-11-23 |
Elan Pharm Inc |
Composto e seus sais farmaceuticamente aceitáveis, composição farmacêutica e método de tratar seres humanos ou animais que sofrem de doenças ou condições
|
|
CH698246B1
(de)
|
2001-12-20 |
2009-06-30 |
Hoffmann La Roche |
Test zur Identifizierung von Inhibitoren von Beta-Sekretasen.
|
|
BR0306724A
(pt)
|
2002-01-04 |
2006-04-11 |
Elan Pharm Inc |
carboxamidas amino substituìdas para tratamento de doença de alzheimer
|
|
EP1469810A4
(en)
|
2002-01-04 |
2009-01-14 |
Univ Rockefeller |
COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING BETA-AMYLOID PEPTIDE-RELATED DISORDERS
|
|
EP1467729A1
(en)
|
2002-01-18 |
2004-10-20 |
The Genetics Company Inc. |
Beta-secretase inhibitors
|
|
US7053220B2
(en)
|
2002-02-01 |
2006-05-30 |
Elan Pharmaceuticals, Inc. |
Hydroxyalkanoyl aminopyrazoles and related compounds
|
|
US20040171614A1
(en)
|
2002-02-06 |
2004-09-02 |
Schering-Plough Corporation |
Novel gamma secretase inhibitors
|
|
TW200302717A
(en)
|
2002-02-06 |
2003-08-16 |
Schering Corp |
Novel gamma secretase inhibitors
|
|
US7256186B2
(en)
|
2002-02-06 |
2007-08-14 |
Schering Corporation |
Gamma secretase inhibitors
|
|
US20040058313A1
(en)
|
2002-04-24 |
2004-03-25 |
Abreu Marcio Marc |
Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
|
|
ATE448242T1
(de)
|
2002-04-24 |
2009-11-15 |
Hiroshi Mori |
Gamma-sekretase-inhibitoren
|
|
ATE435219T1
(de)
|
2002-05-01 |
2009-07-15 |
Merck Sharp & Dohme |
Heteroaryl substituierte spirocyclische sulfamide zur hemmung von gamma sekretase
|
|
US6974829B2
(en)
|
2002-05-07 |
2005-12-13 |
Elan Pharmaceuticals, Inc. |
Succinoyl aminopyrazoles and related compounds
|
|
DE10223666B4
(de)
*
|
2002-05-28 |
2006-06-14 |
Windmöller & Hölscher Kg |
Farbwerksaufbau bei Flexodruckmaschinen
|
|
US6723755B2
(en)
|
2002-06-12 |
2004-04-20 |
Piotr Chomczynski |
Method of treating rosacea
|
|
US20060089355A1
(en)
|
2002-06-11 |
2006-04-27 |
Michel Maillard |
Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides
|
|
US20060154926A1
(en)
|
2002-06-11 |
2006-07-13 |
Elan Pharmaceuticals, Inc. |
Methods of treating alzheimer's disease using aryl alkanoic acid amides
|
|
AU2003247758A1
(en)
|
2002-06-27 |
2004-01-19 |
Elan Pharmaceuticals, Inc. |
Methods for treating alzheimer's disease using hydroxyethylene compounds containing a heterocyclic amide bond isostere
|
|
GB0217909D0
(en)
|
2002-08-01 |
2002-09-11 |
Du Pont |
Chintzed stretch fabrics
|
|
GB0218041D0
(en)
|
2002-08-02 |
2002-09-11 |
Merck Sharp & Dohme |
Chemical process
|
|
US7557137B2
(en)
|
2002-08-05 |
2009-07-07 |
Bristol-Myers Squibb Company |
Gamma-lactams as beta-secretase inhibitors
|
|
WO2004022523A2
(en)
|
2002-09-06 |
2004-03-18 |
Elan Pharmaceuticals, Inc. |
1, 3-diamino-2-hydroxypropane prodrug derivatives
|
|
UY27967A1
(es)
|
2002-09-10 |
2004-05-31 |
Pfizer |
Acetil 2-hindroxi-1,3-diaminoalcanos
|
|
BR0314714A
(pt)
|
2002-09-27 |
2005-08-02 |
Elan Pharm Inc |
Compostos para o tratamento da doença de alzheimer
|
|
US7243510B2
(en)
|
2002-09-30 |
2007-07-17 |
Bp Corporation North America Inc. |
Reduced carbon dioxide emission system and method for providing power for refrigerant compression and electrical power for a light hydrocarbon gas liquefaction process
|
|
AU2003279728B2
(en)
|
2002-10-01 |
2007-09-27 |
Northwestern University |
Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules, and uses thereof
|
|
GB0223038D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
GB0223039D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
JP2006503102A
(ja)
|
2002-10-17 |
2006-01-26 |
ジンギュ リァン |
糖尿病の予防および治療のための天然化合物、その調製方法、およびその薬物的使用。
|
|
WO2004050609A1
(en)
|
2002-11-27 |
2004-06-17 |
Elan Pharmaceutical, Inc. |
Substituted ureas and carbamates
|
|
JP2006510662A
(ja)
|
2002-12-11 |
2006-03-30 |
ファルマシア・アンド・アップジョン・カンパニー・エルエルシー |
α7ニコチン性アセチルコリン受容体アゴニストとその他の化合物との組合せによる疾患の治療
|
|
FR2848452B1
(fr)
|
2002-12-12 |
2007-04-06 |
Aventis Pharma Sa |
Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer
|
|
JP4662914B2
(ja)
|
2003-02-04 |
2011-03-30 |
エフ.ホフマン−ラ ロシュ アーゲー |
ガンマ−セクレターゼ阻害剤としてのマロンアミド誘導体
|
|
WO2004071431A2
(en)
|
2003-02-05 |
2004-08-26 |
Myriad Genetics, Inc. |
Method and composition for treating neurodegenerative disorders
|
|
US7521481B2
(en)
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
GB0308318D0
(en)
|
2003-04-10 |
2003-05-14 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW200505418A
(en)
|
2003-04-21 |
2005-02-16 |
Elan Pharm Inc |
Phenacyl 2-hydroxy-3-diaminoalkanes
|
|
AR044044A1
(es)
|
2003-04-21 |
2005-08-24 |
Elan Pharm Inc |
2-hidroxi-3-diaminoalcanos de benzamida
|
|
TW200510405A
(en)
|
2003-05-13 |
2005-03-16 |
Schering Corp |
Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors
|
|
MXPA05012323A
(es)
|
2003-05-16 |
2006-01-30 |
Merck Sharp & Dohme |
Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
|
|
US7060698B2
(en)
|
2003-05-19 |
2006-06-13 |
Hoffmann-La Roche Inc. |
Benzoxazepinone derivatives
|
|
EP2511267A1
(en)
|
2003-06-05 |
2012-10-17 |
Elan Pharmaceuticals Inc. |
3-((n-acylated aminoacyl)amino)pyrazoles as inhibitors of beta-amyloid peptide production useful for the treatment of alzheimer's disease
|
|
CN100430377C
(zh)
|
2003-06-30 |
2008-11-05 |
麦克公司 |
用于治疗阿尔茨海默病的N-烷基苯基甲酰胺β分泌酶抑制剂
|
|
CN1909897A
(zh)
|
2003-07-01 |
2007-02-07 |
默克公司 |
用于治疗阿尔茨海默病的苯基羧化物β-分泌酶抑制剂
|
|
EP1671129A1
(en)
|
2003-07-21 |
2006-06-21 |
Angiogenetics Sweden AB |
Compounds and methods for promoting angiogenesis by using a gamma-secretase inhibitor or inhibiting the gamma-secretase pathway
|
|
GB0318447D0
(en)
|
2003-08-05 |
2003-09-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP4448134B2
(ja)
|
2003-08-08 |
2010-04-07 |
シェーリング コーポレイション |
ベンズアミド置換基を有する環状アミンbase−1阻害剤
|
|
JP2007502278A
(ja)
|
2003-08-14 |
2007-02-08 |
メルク エンド カムパニー インコーポレーテッド |
アルツハイマー病の治療のための大員環β−セクレターゼ阻害剤
|
|
CA2539042A1
(en)
|
2003-09-24 |
2005-04-07 |
Merck Sharp & Dohme Limited |
Gamma-secretase inhibitors
|
|
KR100793095B1
(ko)
|
2003-10-01 |
2008-01-10 |
주식회사 프로메디텍 |
Bace 저해효능을 가진 신규한 술폰 아미드 유도체
|
|
ATE396973T1
(de)
|
2003-10-03 |
2008-06-15 |
Merck & Co Inc |
Benzylether- und benzylamino-beta-sekretase- hemmer zur behandlung von alzheimer-krankheit
|
|
GB0323258D0
(en)
|
2003-10-04 |
2003-11-05 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
PL1673347T3
(pl)
|
2003-10-06 |
2016-01-29 |
Hoffmann La Roche |
Podstawione pochodne dibenzo-azepiny i benzo-diazepiny użyteczne jako inhibitory gamma-sekretazy
|
|
DK2058390T3
(da)
|
2003-10-14 |
2013-05-06 |
Hokko Chem Ind Co |
Fremgangsmåde til fremstilling af scyllo-inositol
|
|
US20050171112A1
(en)
|
2003-11-03 |
2005-08-04 |
Probiodrug Ag |
Combinations useful for the treatment of neuronal disorders
|
|
GB0326039D0
(en)
|
2003-11-07 |
2003-12-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ES2232302B1
(es)
|
2003-11-07 |
2006-08-01 |
Universitat De Les Illes Balears |
Myo-inositol hexafosfato para uso topico.
|
|
DE602004011255T2
(de)
|
2003-11-11 |
2009-01-08 |
F. Hoffmann-La Roche Ag |
Phosphinsäurederivate, inhibitoren von beta-sekretase zur behandlung von alzheimer-krankheit
|
|
CA2546142A1
(en)
|
2003-11-24 |
2005-06-09 |
Merck & Co., Inc. |
Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
MXPA06005734A
(es)
|
2003-11-28 |
2006-08-17 |
Hoffmann La Roche |
Acidos tetronico y tetramico como inhibidores de beta-secretasa.
|
|
EP1697308B1
(en)
|
2003-12-19 |
2014-03-19 |
Merck Sharp & Dohme Corp. |
Phenylamide and pyridylamide beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
KR100803996B1
(ko)
|
2003-12-31 |
2008-02-18 |
포항공과대학교 산학협력단 |
아밀로이드 전구체 단백질 프로세싱 저해제
|
|
AU2004315399B2
(en)
|
2004-01-29 |
2009-08-06 |
Cellzome Ag |
Treatment of neurodegenerative diseases by the use of ATP7A-modulators
|
|
DK1713501T3
(da)
|
2004-01-29 |
2008-05-26 |
Cellzome Ag |
Behandling af neurodegenerative sygdomme ved anvendelse af GPR49
|
|
WO2005095326A2
(en)
|
2004-03-25 |
2005-10-13 |
Elan Pharmaceuticals, Inc. |
2-amino- and 2-thio-substituted 1,3-diaminopropanes
|
|
US20070203147A1
(en)
|
2004-03-30 |
2007-08-30 |
Coburn Craig A |
2-Aminothiazole Compounds Useful As Aspartyl Protease Inhibitors
|
|
KR20070010144A
(ko)
|
2004-04-05 |
2007-01-22 |
쉐링 코포레이션 |
신규한 감마 세크레타제 억제제
|
|
EP1740581B1
(en)
|
2004-04-20 |
2012-08-22 |
Merck Sharp & Dohme Corp. |
2, 4, 6-substituted pyridyl derivative compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
CA2563615A1
(en)
|
2004-04-20 |
2005-11-03 |
Merck & Co., Inc. |
1,3,5-substituted phenyl derivative compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
CA2566053A1
(en)
|
2004-05-13 |
2005-12-01 |
Merck & Co., Inc. |
Phenyl carboxamide compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
US20060004096A1
(en)
|
2004-05-28 |
2006-01-05 |
Joseph Larner |
Method of Treating Endothelial Dysfunction, Oxidative Stress and Related Diseases
|
|
JP4406327B2
(ja)
|
2004-06-29 |
2010-01-27 |
儀昭 新田 |
タイヤチップ製造装置
|
|
US8193250B2
(en)
|
2004-10-22 |
2012-06-05 |
Mount Sinai School Of Medicine |
Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system
|
|
ZA200704872B
(en)
|
2004-11-17 |
2008-12-31 |
Mclaurin Joanne |
Compositions comprising scyllo-inositol derivatives and methods to treat disorders of protein aggregation
|
|
WO2006088705A1
(en)
|
2005-02-14 |
2006-08-24 |
Wyeth |
Terphenyl guanidines as [beta symbol] -secretase inhibitors
|
|
WO2006112000A1
(ja)
|
2005-03-30 |
2006-10-26 |
The Niigata Institute Of Science And Technology |
大腸菌変異株による2-デオキシ-シロ-イノソースの合成および精製する方法並びに得られた2-デオキシ-シロ-イノソース
|
|
KR20060105233A
(ko)
|
2005-04-02 |
2006-10-11 |
삼성전자주식회사 |
하이브리드 디스크, 그 기록 및/또는 재생 장치 및 방법
|
|
WO2007002220A2
(en)
|
2005-06-21 |
2007-01-04 |
Bristol-Myers Squibb Company |
Aminoacetamide acyl guanidines as beta-secretase inhibitors
|
|
AU2006270084B2
(en)
|
2005-07-18 |
2011-08-25 |
Merck Sharp & Dohme Corp. |
Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease
|
|
US20090182021A1
(en)
|
2005-08-03 |
2009-07-16 |
Nanternet Philippe G |
Tricyclic Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
|
|
WO2007021793A1
(en)
|
2005-08-12 |
2007-02-22 |
Bristol-Myers Squibb Company |
Macrocyclic diaminopropanes as beta-secretase inhibitors
|
|
US20090170957A1
(en)
|
2005-10-13 |
2009-07-02 |
Antonio Cruz |
Scyllo-inositol derivatives and their use in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
|
|
ATE502036T1
(de)
|
2005-10-25 |
2011-04-15 |
Janssen Pharmaceutica Nv |
Als inhibitoren von beta-sekretase (bace) geeignete 2-amino-3,4-dihydropyridoä3,4- düpyrimidinderivate
|
|
US20070197453A1
(en)
|
2006-02-17 |
2007-08-23 |
Mclaurin Joanne |
Compositions and methods for treatment of disorders of protein aggregation
|
|
US20070197452A1
(en)
|
2006-02-17 |
2007-08-23 |
Mclaurin Joanne |
Treatment of amyloid-related diseases
|
|
CA2579188A1
(en)
|
2006-02-17 |
2007-08-17 |
Joanne Mclaurin |
Treatment of amyloid-related diseases
|
|
CA2644804A1
(en)
|
2006-03-09 |
2007-09-13 |
Waratah Pharmaceuticals Inc. |
A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation
|
|
CA2652238A1
(en)
|
2006-05-18 |
2007-11-29 |
Merck Frosst Canada Ltd. |
Phenanthrene derivatives as mpges-1 inhibitors
|
|
WO2007134449A1
(en)
|
2006-05-19 |
2007-11-29 |
Waratah Pharmaceuticals Inc. |
Screening methods for amyloid beta modulators
|
|
EP1884531A1
(en)
|
2006-07-30 |
2008-02-06 |
Lonza Compounds GmbH & Co. KG |
Sheet molding compounds (smc) comprising thermosetting resins based on renewable resources
|
|
CA2697675A1
(en)
|
2006-08-25 |
2008-02-28 |
Allan Basbaum |
Intrathecal administration of triptan compositions to treat non-migraine pain
|
|
CN101511304A
(zh)
|
2006-09-06 |
2009-08-19 |
奥尔特克斯公司 |
人工心脏瓣膜、系统和移植方法
|
|
WO2008034244A1
(en)
|
2006-09-21 |
2008-03-27 |
Waratah Pharmaceuticals Inc. |
The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases
|
|
CA2670405A1
(en)
|
2006-11-24 |
2008-05-29 |
Waratah Pharmaceuticals Inc. |
Combination treatments for alzheimer's disease and related neurodegenerative diseases
|
|
CN101686986A
(zh)
|
2006-12-29 |
2010-03-31 |
诺尔姆奥克西斯公司 |
环多醇和其衍生物及其治疗应用
|
|
WO2008098371A1
(en)
|
2007-02-16 |
2008-08-21 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
Compositions and method for reducing amyloid beta in a mammal
|
|
US20110105626A1
(en)
|
2007-04-12 |
2011-05-05 |
Mclaurin Joanne |
Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
|
|
US20100331267A1
(en)
|
2007-04-12 |
2010-12-30 |
Mclaurin Joanne |
Use of cyclohexanehexol derivatives in the treatment of alpha-synucleinopathies
|
|
WO2008124931A1
(en)
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis
|
|
EP2656839A1
(en)
|
2007-04-12 |
2013-10-30 |
Waratah Pharmaceuticals, Inc. |
Use of Cyclohexanehexol Derivatives in the Treatment of Ocular Diseases
|
|
JP5034916B2
(ja)
|
2007-12-10 |
2012-09-26 |
富士通セミコンダクター株式会社 |
性能評価モデル生成方法、システム性能評価方法、及び性能評価モデル生成装置
|
|
BRPI0912075A2
(pt)
|
2008-08-06 |
2017-05-23 |
Invista Technologies Sarl |
"artigo que compreende ao menos um substrato relativamente não elástico, um material de poliuretano selecionado a partir do grupo que consiste em um filme e um ou mais filamentos, processo para fabricar uma estrutura compósita elástica e processo para fabricar uma estrutura laminada compósita multicamada elástica"
|
|
CA2737163C
(en)
|
2008-09-15 |
2019-03-12 |
Elan Pharmaceuticals, Inc. |
Methods of treatment of hyperuricemia and associated disease states
|
|
CA2740124A1
(en)
|
2008-10-09 |
2010-04-15 |
Waratah Pharmaceuticals Inc. |
Use of scyllo-inositols for the treatment of macular degeneration-related disorders
|
|
CA2837926A1
(en)
|
2011-06-03 |
2012-12-20 |
Susan ABUSHAKRA |
Scyllo - inositol for the treatment of behavioral and psychiatric disorders
|