EP2349233A4 - Use of scyllo-inositols for the treatment of macular degeneration-related disorders - Google Patents

Use of scyllo-inositols for the treatment of macular degeneration-related disorders

Info

Publication number
EP2349233A4
EP2349233A4 EP09818730A EP09818730A EP2349233A4 EP 2349233 A4 EP2349233 A4 EP 2349233A4 EP 09818730 A EP09818730 A EP 09818730A EP 09818730 A EP09818730 A EP 09818730A EP 2349233 A4 EP2349233 A4 EP 2349233A4
Authority
EP
European Patent Office
Prior art keywords
scyllo
inositols
treatment
macular degeneration
related disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09818730A
Other languages
German (de)
French (fr)
Other versions
EP2349233A1 (en
Inventor
Antonio Cruz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waratah Pharmaceuticals Inc
Original Assignee
Waratah Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waratah Pharmaceuticals Inc filed Critical Waratah Pharmaceuticals Inc
Publication of EP2349233A1 publication Critical patent/EP2349233A1/en
Publication of EP2349233A4 publication Critical patent/EP2349233A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP09818730A 2008-10-09 2009-10-09 Use of scyllo-inositols for the treatment of macular degeneration-related disorders Withdrawn EP2349233A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10409408P 2008-10-09 2008-10-09
PCT/CA2009/001448 WO2010040232A1 (en) 2008-10-09 2009-10-09 Use of scyllo-inositols for the treatment of macular degeneration-related disorders

Publications (2)

Publication Number Publication Date
EP2349233A1 EP2349233A1 (en) 2011-08-03
EP2349233A4 true EP2349233A4 (en) 2012-04-18

Family

ID=42099427

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09818730A Withdrawn EP2349233A4 (en) 2008-10-09 2009-10-09 Use of scyllo-inositols for the treatment of macular degeneration-related disorders

Country Status (7)

Country Link
US (1) US20100093648A1 (en)
EP (1) EP2349233A4 (en)
JP (1) JP2012505162A (en)
AU (1) AU2009301603A1 (en)
CA (1) CA2740124A1 (en)
WO (1) WO2010040232A1 (en)
ZA (1) ZA201102640B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
EP2044951A1 (en) 2007-10-02 2009-04-08 Merz Pharma GmbH & Co. KGaA The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
US9381183B2 (en) 2012-07-18 2016-07-05 Physicians Recommended Nutriceuticals, Llc Methods for improving the quality of the meibum composition of meibomian glands
US10709680B2 (en) 2011-07-18 2020-07-14 Physicians Recommended Nutriceuticals, Llc Methods for treating dry eye
US9115078B2 (en) 2011-07-18 2015-08-25 Physicians Recommended Nutriceuticals, Llc Compositions for improving the quality of the meibum composition of inflamed or dysfunctional meibomian glands
US20210121430A1 (en) 2011-07-18 2021-04-29 Prn Physician Recommended Nutriceuticals, Llc Omega-3 fatty acid supplementation for use in treating dry eye
ES2948322T3 (en) 2012-06-01 2023-09-08 Novartis Ag Syringe
TW201412325A (en) 2012-06-20 2014-04-01 梅茲製藥有限兩合公司 Interval therapy for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
CN103070992B (en) * 2013-01-11 2014-07-02 管学刚 Medicine for treating high myopia macular hemorrhages
WO2015116735A1 (en) 2014-01-28 2015-08-06 Mayo Foundation For Medical Education And Research Methods and combinations for killing senescent cells and for treating senescence-associated diseases and disorders
EP3099380B1 (en) 2014-01-28 2021-08-11 Buck Institute for Research on Aging Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
US10328058B2 (en) 2014-01-28 2019-06-25 Mayo Foundation For Medical Education And Research Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques
US9173915B1 (en) 2014-10-10 2015-11-03 Peter F. Kador Antioxidant eye drops
PL3233174T3 (en) * 2014-12-19 2021-08-30 Kemin Industries, Inc. Intraocular delivery of bioactive molecules using iontophoresis
PT3416622T (en) * 2016-02-15 2023-08-28 Kemin Ind Inc Positively charged liposomes as lipophilic molecule carriers
WO2019213462A1 (en) * 2018-05-03 2019-11-07 Normoxys, Inc. Inositol-based immunotherapies
WO2022155242A1 (en) * 2021-01-12 2022-07-21 The Regents Of The University Of Michigan Treatment and prevention of dry macular degeneration

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008124940A1 (en) * 2007-04-12 2008-10-23 Waratah Pharmaceuticals Inc. Use of cyclohexanehexol derivatives in the treatment of ocular diseases

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454151A (en) * 1982-03-22 1984-06-12 Syntex (U.S.A.) Inc. Use of pyrrolo pyrroles in treatment of ophthalmic diseases
US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4474806A (en) * 1982-05-10 1984-10-02 Merck & Co., Inc. Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents
US4952396A (en) * 1986-11-19 1990-08-28 Linus Pauling Institute Of Science & Medicine Method of using phytic acid for inhibiting tumor growth
US4758430A (en) * 1987-01-21 1988-07-19 Robert Sabin Method of treatment of Alzheimer's disease using phytic acid
US4847082A (en) * 1987-01-21 1989-07-11 Robert Sabin Method of treatment of Alzheimer's disease using phytic acid
SE8904355D0 (en) * 1989-12-21 1989-12-21 Perstorp Ab medicament
US5217959A (en) * 1990-09-06 1993-06-08 Robert Sabin Method of treating multiple sclerosis with phytic acid
US5112814A (en) * 1990-10-24 1992-05-12 Robert Sabin Method of treatment of Parkinson's disease using phytic acid
KR0185215B1 (en) * 1990-11-30 1999-05-01 요시다 쇼오지 A controlled-release pharmaceutical preparation for intra-ocular implant
SE9102068L (en) * 1991-07-03 1993-01-04 Perstorp Ab DERIVATIVES OF INOSITOL, COMPOSITIONS CONTAINING THESE AND USE THEREOF
SE469260B (en) * 1992-02-25 1993-06-14 Perstorp Ab A PHARMACEUTICAL COMPOSITION WITH PREPARED BIO-ACCESSIBILITY FOR INOSITOL PHOSPHATE
EP1225175B1 (en) * 1992-10-05 2005-03-30 Virginia Tech Intellectual Properties, Inc. Intermediate for the synthesis of D-chiro-3-inosose and (+)-D-chiro-inositol
US5643562A (en) * 1993-03-29 1997-07-01 Queen's University Of Kingston Method for treating amyloidosis
US5972328A (en) * 1993-03-29 1999-10-26 Queen's University At Kingston Method for treating amyloidosis
US5840294A (en) * 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
ATE244302T1 (en) * 1993-04-05 2003-07-15 Aveve Nv PHYTATE HYDROLYSIS AND ENZYMATIC COMPOSITION FOR THE HYDROLYSIS OF PHYTATE
KR100332144B1 (en) * 1993-08-11 2002-11-13 자이단 호진 비세부츠 가가쿠 겐쿠 카이 D-Kiro-Inositol Production Method
SE502574C2 (en) * 1994-01-25 1995-11-13 Perstorp Ab A pharmaceutical composition with improved bioavailability of inositol phosphate
US5858326A (en) * 1995-06-06 1999-01-12 Neurochem, Inc. Methods of increasing amyloid deposition
US5756541A (en) * 1996-03-11 1998-05-26 Qlt Phototherapeutics Inc Vision through photodynamic therapy of the eye
US6232486B1 (en) * 1996-06-11 2001-05-15 Nutrimed Biotech Molecular probes and modulators for PI-PLC and PI 3-kinase
US5977078A (en) * 1996-09-20 1999-11-02 The Regents Of The Univesity Of California Inositol polyphosphate derivatives and methods of using same
US5880099A (en) * 1996-09-20 1999-03-09 The Regents Of The University Of California Inositol polyphosphates and methods of using same
US5998485A (en) * 1997-06-16 1999-12-07 Cedars-Sinai Medical Center Method for modulating immune response with inositol
US6153603A (en) * 1997-06-27 2000-11-28 Perstorp Ab Method of treating angiogenesis in tumor tissue
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
US6818430B1 (en) * 1999-06-07 2004-11-16 Hokko Chemical Industry Co., Ltd. Process for producing L-epi-2-inosose and novel process for producing epi-inositol
US6329256B1 (en) * 1999-09-24 2001-12-11 Advanced Micro Devices, Inc. Self-aligned damascene gate formation with low gate resistance
RU2002111408A (en) * 1999-10-18 2004-05-20 Мусклетеч Ресеч Энд Девелопмент Инк. (Ca) FOOD ADDITIVE FOR INCREASING MUSCLE WEIGHT AND STRENGTH
US7728043B2 (en) * 1999-10-22 2010-06-01 Kim Darrick S H L Methods for treatment of beta-amyloid protein-induced ocular disease
US6887898B1 (en) * 1999-10-22 2005-05-03 Darrick S. H. L. Kim Pharmaceutical compositions useful in prevention and treatment of beta-Amyloid protein-induced disease
US6331313B1 (en) * 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
DE10031955A1 (en) * 2000-06-30 2002-01-17 Deutsches Krebsforsch Curcumin derivatives with improved water solubility compared to curcumin and medicaments containing them
US7060695B2 (en) * 2001-02-06 2006-06-13 Qlt, Inc. Method to prevent vision loss
ATE554763T1 (en) * 2001-02-06 2012-05-15 Quadra Logic Tech Inc PHOTODYNAMIC THERAPY OF OCCULT CHORIOIDAL NEOVASCULARIZATION ASSOCIATED WITH AGE-RELATED MACULAR DEGENERATION
US20030181531A1 (en) * 2003-02-11 2003-09-25 David Sherris Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases
WO2003007944A1 (en) * 2001-07-20 2003-01-30 Qlt, Inc. Treatment of macular edema with photodynamic therapy
US20040058313A1 (en) * 2002-04-24 2004-03-25 Abreu Marcio Marc Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
US20050142191A1 (en) * 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
PT1674578E (en) * 2003-10-14 2010-05-21 Hokko Chem Ind Co Process for producing scyllo-inositol
EP1841460A2 (en) * 2004-06-18 2007-10-10 Neurochem (International) Limited Therapeutic formulations for the treatment of beta-amyloid related diseases
AU2005306531B2 (en) * 2004-11-17 2012-02-23 Joanne Mclaurin Compositions comprising scyllo-inositol derivatives and methods to treat disorders of protein aggregation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008124940A1 (en) * 2007-04-12 2008-10-23 Waratah Pharmaceuticals Inc. Use of cyclohexanehexol derivatives in the treatment of ocular diseases

Also Published As

Publication number Publication date
US20100093648A1 (en) 2010-04-15
CA2740124A1 (en) 2010-04-15
WO2010040232A1 (en) 2010-04-15
EP2349233A1 (en) 2011-08-03
JP2012505162A (en) 2012-03-01
AU2009301603A1 (en) 2010-04-15
ZA201102640B (en) 2012-09-26

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20110428

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20120321

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/395 20060101AFI20120315BHEP

Ipc: A61K 9/00 20060101ALI20120315BHEP

Ipc: A61P 27/02 20060101ALI20120315BHEP

Ipc: A61K 31/7004 20060101ALI20120315BHEP

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Effective date: 20121023