SI1177167T1 - High purity (1r, 2s, 4r)-(-)-2-((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them. - Google Patents

High purity (1r, 2s, 4r)-(-)-2-((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them.

Info

Publication number
SI1177167T1
SI1177167T1 SI200030292T SI200030292T SI1177167T1 SI 1177167 T1 SI1177167 T1 SI 1177167T1 SI 200030292 T SI200030292 T SI 200030292T SI 200030292 T SI200030292 T SI 200030292T SI 1177167 T1 SI1177167 T1 SI 1177167T1
Authority
SI
Slovenia
Prior art keywords
bicyclo
heptane
dimethylamino
ethoxy
tri
Prior art date
Application number
SI200030292T
Other languages
English (en)
Slovenian (sl)
Inventor
Gyula Lukacs
Gyula Simig
Tibor Mezei
Zoltan Budai
Marta Porcs-Makkay
Gyrgy KRASZNAI
Kalman Nagy
DONATH Gy�rgyi VERECZKEYNE
Tibor Szabo
Norbert Nemeth
Janos Szulagyi
Original Assignee
Egis Gyogyszergyar Reszvenytarsasag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Reszvenytarsasag filed Critical Egis Gyogyszergyar Reszvenytarsasag
Publication of SI1177167T1 publication Critical patent/SI1177167T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/12—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200030292T 1999-05-11 2000-05-10 High purity (1r, 2s, 4r)-(-)-2-((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them. SI1177167T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9901559A HU227114B1 (en) 1999-05-11 1999-05-11 (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same
EP00929730A EP1177167B1 (en) 1999-05-11 2000-05-10 High purity (1r, 2s, 4r)-(-)-2-[(2'-(n,n-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them.
PCT/HU2000/000044 WO2000068183A2 (en) 1999-05-11 2000-05-10 High purity (1r,2s,4r)-(-)-2-[(2'-{n,n-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them

Publications (1)

Publication Number Publication Date
SI1177167T1 true SI1177167T1 (en) 2004-04-30

Family

ID=89998272

Family Applications (4)

Application Number Title Priority Date Filing Date
SI200030292T SI1177167T1 (en) 1999-05-11 2000-05-10 High purity (1r, 2s, 4r)-(-)-2-((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them.
SI200030124T SI1052245T1 (en) 1999-05-11 2000-05-10 High purity (1R, 2S, 4R)-(-)-2-((2'-(N,N-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them
SI200030219T SI1052243T1 (en) 1999-05-11 2000-05-10 Process for preparing (1R, 2S, 4R)-(-)-2-((2'-(N,N-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof
SI200030989T SI1177166T1 (sl) 1999-05-11 2000-05-10 Postopek za pripravo (1R,2S,4R)-(-)-2-((2-N,N-dimetilamino)-etoksi)-2-(fenil)-1,7,7,-tri- (metil)-biciklo (2.2.1)heptana in njegovih farmacevtsko sprejemljivih kislinskih adicijskih soli

Family Applications After (3)

Application Number Title Priority Date Filing Date
SI200030124T SI1052245T1 (en) 1999-05-11 2000-05-10 High purity (1R, 2S, 4R)-(-)-2-((2'-(N,N-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them
SI200030219T SI1052243T1 (en) 1999-05-11 2000-05-10 Process for preparing (1R, 2S, 4R)-(-)-2-((2'-(N,N-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof
SI200030989T SI1177166T1 (sl) 1999-05-11 2000-05-10 Postopek za pripravo (1R,2S,4R)-(-)-2-((2-N,N-dimetilamino)-etoksi)-2-(fenil)-1,7,7,-tri- (metil)-biciklo (2.2.1)heptana in njegovih farmacevtsko sprejemljivih kislinskih adicijskih soli

Country Status (38)

Country Link
US (3) US6335469B1 (da)
EP (4) EP1052243B1 (da)
JP (2) JP4031203B2 (da)
KR (3) KR100581489B1 (da)
CN (2) CN1325465C (da)
AR (2) AR020860A1 (da)
AT (4) ATE252544T1 (da)
AU (2) AU777737B2 (da)
BG (2) BG64442B1 (da)
BR (2) BR0010406A (da)
CA (2) CA2373193A1 (da)
CO (1) CO5170480A1 (da)
CZ (4) CZ290734B6 (da)
DE (4) DE60038112T8 (da)
DK (4) DK1052243T3 (da)
EA (2) EA002164B1 (da)
EE (2) EE04638B1 (da)
ES (4) ES2194643T3 (da)
FR (2) FR2793490B1 (da)
HK (2) HK1031220A1 (da)
HR (2) HRP20000290B1 (da)
HU (1) HU227114B1 (da)
IL (4) IL146421A0 (da)
IS (2) IS2570B (da)
LT (2) LT4928B (da)
MX (2) MXPA01011420A (da)
MY (2) MY123523A (da)
NO (2) NO321486B1 (da)
NZ (2) NZ515918A (da)
PL (2) PL202956B1 (da)
PT (4) PT1052245E (da)
SI (4) SI1177167T1 (da)
SK (4) SK285635B6 (da)
TR (2) TR200200148T2 (da)
TW (2) TWI286541B (da)
UA (2) UA49974C2 (da)
WO (2) WO2000068181A2 (da)
ZA (2) ZA200108956B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227114B1 (en) * 1999-05-11 2010-07-28 Egis Gyogyszergyar Nyilvanosan (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same
US6589996B2 (en) 2000-03-17 2003-07-08 Orion Corporation Treatment of disorders relating to the serotonergic system
US20040082665A1 (en) * 2001-01-22 2004-04-29 Outi Maki-Ikola Method for treating stress or tension
HUP0103017A3 (en) * 2001-07-18 2004-05-28 Egis Gyogyszergyar Nyilvanosan Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
HUP0301906A3 (en) * 2003-06-23 2006-03-28 Egis Gyogyszergyar Nyilvanosan Use of bicyclo[2.2.1]heptane derivatives for producing of pharmaceutical compositions having neuroprotectiv activity
DE602004017062D1 (de) * 2004-03-12 2008-11-20 Egis Gyogyszergyar Nyrt Zusammensetzungen aus deramciclan und opioiden zur verwendung als schmerzmittel
JP4916680B2 (ja) * 2005-06-30 2012-04-18 株式会社半導体エネルギー研究所 半導体装置の作製方法、剥離方法
US20080258121A1 (en) * 2007-04-23 2008-10-23 Hasan Farooq Fire Retardant Composition
WO2011061744A2 (en) 2009-11-19 2011-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Novel arylated camphenes, processes for their preparation and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179164B (en) 1979-12-14 1982-08-28 Egyt Gyogyszervegyeszeti Gyar Process for producing cycloalkyl-ethers of alkanolamines
HU212574B (en) * 1990-09-21 1996-08-29 Egyt Gyogyszervegyeszeti Gyar Process for producing (1r,2s)-(-)-2-phenyl-(2'-dimethyl-amino-etoxy)-1,7,7-trimethyl-bicyclo[2.2.1.]heptane
HU214588B (hu) * 1994-07-01 1998-04-28 EGIS Gyógyszergyár Rt. Eljárás bicikloheptán-származékot tartalmazó, CCK-rendszer gátló hatású gyógyászati készítmények előállítására
HU226061B1 (en) 1996-10-17 2008-04-28 Egis Gyogyszergyar Nyilvanosan 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation
HUP9900445A2 (hu) * 1999-02-24 2001-06-28 EGIS Gyógyszergyár Rt. Eljárás (1R,2S,4R)-(-)-N,N-(dimetilamino-etoxi)-2-fenil-1,7,7-trimetil-biciklo[2.2.1]heptán előállítására és ennek köztiterméke
HU227114B1 (en) * 1999-05-11 2010-07-28 Egis Gyogyszergyar Nyilvanosan (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same

Also Published As

Publication number Publication date
PT1177166E (pt) 2008-06-02
PL202956B1 (pl) 2009-08-31
AU776696B2 (en) 2004-09-16
EA002164B1 (ru) 2001-12-24
IS6153A (is) 2001-11-09
EP1052243B1 (en) 2003-07-30
AU4600300A (en) 2000-11-21
HRP20000291A2 (en) 2001-06-30
US6624201B2 (en) 2003-09-23
ES2302694T3 (es) 2008-08-01
NO321487B1 (no) 2006-05-15
EE04638B1 (et) 2006-06-15
CZ20001722A3 (cs) 2000-12-13
DE60002117T2 (de) 2003-12-24
JP2002544184A (ja) 2002-12-24
NO20015336D0 (no) 2001-10-31
AU777737B2 (en) 2004-10-28
DE60038112T8 (de) 2009-05-28
IL146421A0 (en) 2002-07-25
PT1177167E (pt) 2004-03-31
MY122508A (en) 2006-04-29
NO20015352L (no) 2002-01-08
FR2793490A1 (fr) 2000-11-17
FR2793490B1 (fr) 2004-04-23
EP1052243A3 (en) 2001-02-28
TR200200148T2 (tr) 2002-06-21
NO20015336L (no) 2002-01-08
CZ290734B6 (cs) 2002-10-16
BR0010412A (pt) 2002-02-13
CA2369393A1 (en) 2000-11-16
UA49974C2 (uk) 2002-10-15
EA002163B1 (ru) 2001-12-24
BG104416A (en) 2001-03-30
WO2000068183A3 (en) 2001-07-26
US20020040164A1 (en) 2002-04-04
DK1177167T3 (da) 2004-03-01
DE60004126T2 (de) 2004-04-22
DE60004126D1 (de) 2003-09-04
PL340107A1 (en) 2000-11-20
EP1052245A2 (en) 2000-11-15
CN1353687A (zh) 2002-06-12
PT1052245E (pt) 2003-09-30
SI1177166T1 (sl) 2008-08-31
EA200000411A2 (ru) 2000-12-25
JP2002544185A (ja) 2002-12-24
CA2373193A1 (en) 2000-11-16
EA200000410A2 (ru) 2000-12-25
SI1052245T1 (en) 2003-10-31
EP1052243A2 (en) 2000-11-15
CN1325465C (zh) 2007-07-11
BG64673B1 (bg) 2005-11-30
KR100581489B1 (ko) 2006-05-22
SK6892000A3 (en) 2000-12-11
ES2203373T3 (es) 2004-04-16
HK1031372A1 (en) 2001-06-15
EP1177166A2 (en) 2002-02-06
WO2000068181A3 (en) 2001-06-28
IS6152A (is) 2001-11-09
PT1052243E (pt) 2003-12-31
EE04672B1 (da) 2006-08-15
ZA200108956B (en) 2003-02-17
SK16232001A3 (sk) 2002-04-04
SK285780B6 (sk) 2007-08-02
CN1353686A (zh) 2002-06-12
LT4927B (lt) 2002-07-25
ZA200108958B (en) 2002-10-30
DK1052245T3 (da) 2003-08-11
AU4773100A (en) 2000-11-21
EE200100595A (et) 2003-02-17
AR023900A1 (es) 2002-09-04
HRP20000290B1 (en) 2007-08-31
CZ20014050A3 (cs) 2002-05-15
DK1177166T3 (da) 2008-06-16
WO2000068183A2 (en) 2000-11-16
IL146420A0 (en) 2002-07-25
DE60038112D1 (de) 2008-04-03
CO5170480A1 (es) 2002-06-27
LT4928B (lt) 2002-07-25
EE200100596A (et) 2003-02-17
SK16242001A3 (sk) 2002-04-04
TR200200147T2 (tr) 2002-06-21
HU227114B1 (en) 2010-07-28
CZ291329B6 (cs) 2003-02-12
ES2194643T3 (es) 2003-12-01
MXPA01011423A (es) 2002-06-04
TWI286541B (en) 2007-09-11
TW528742B (en) 2003-04-21
SI1052243T1 (en) 2004-02-29
HRP20000290A2 (en) 2005-02-28
LT2001108A (en) 2002-03-25
EP1177166B1 (en) 2008-02-20
EA200000410A3 (ru) 2001-02-26
MY123523A (en) 2006-05-31
CZ20014051A3 (cs) 2002-05-15
EP1177167B1 (en) 2003-10-22
KR100685071B1 (ko) 2007-02-22
CZ20001723A3 (cs) 2000-12-13
MXPA01011420A (es) 2002-06-04
SK285635B6 (sk) 2007-05-03
DE60002117D1 (de) 2003-05-22
FR2793489B1 (fr) 2004-04-02
JP4031203B2 (ja) 2008-01-09
US6242386B1 (en) 2001-06-05
CN1173928C (zh) 2004-11-03
EP1177167A2 (en) 2002-02-06
JP4536265B2 (ja) 2010-09-01
SK6902000A3 (en) 2000-12-11
ATE246170T1 (de) 2003-08-15
ATE252544T1 (de) 2003-11-15
WO2000068181A2 (en) 2000-11-16
KR20010112486A (ko) 2001-12-20
HRP20000291B1 (en) 2005-06-30
US6335469B1 (en) 2002-01-01
ATE386714T1 (de) 2008-03-15
BG64442B1 (en) 2005-02-28
DK1052243T3 (da) 2003-11-24
LT2001109A (en) 2002-03-25
DE60038112T2 (de) 2009-02-12
KR20060010874A (ko) 2006-02-02
NZ515917A (en) 2004-02-27
IS2570B (is) 2010-01-15
IL146420A (en) 2007-06-03
BG104417A (en) 2001-03-30
CA2369393C (en) 2010-07-06
KR20020010914A (ko) 2002-02-06
PL340108A1 (en) 2000-11-20
AR020860A1 (es) 2002-05-29
ES2208328T3 (es) 2004-06-16
NZ515918A (en) 2004-02-27
ATE237579T1 (de) 2003-05-15
FR2793489A1 (fr) 2000-11-17
HUP9901559A2 (hu) 2002-01-28
NO321486B1 (no) 2006-05-15
HK1031220A1 (en) 2001-06-08
EP1052245B1 (en) 2003-04-16
DE60006097D1 (de) 2003-11-27
DE60006097T2 (de) 2004-06-17
EA200000411A3 (ru) 2001-02-26
BR0010406A (pt) 2002-02-13
UA61122C2 (uk) 2003-11-17
HU9901559D0 (en) 1999-07-28
NO20015352D0 (no) 2001-11-01
IL146421A (en) 2008-11-26
EP1052245A3 (en) 2001-02-28

Similar Documents

Publication Publication Date Title
CA2386690A1 (en) Pharmaceutical tramadol salts
PL354322A1 (en) 2'-substituted 1,1'-biphenyl-2-carbonamides, method for the production thereof, use thereof as a medicament and pharmaceutical preparations containing said compounds
SI1052245T1 (en) High purity (1R, 2S, 4R)-(-)-2-((2'-(N,N-dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri-(methyl)-bicyclo(2.2.1)heptane and pharmaceutically acceptable acid addition salts thereof, process for the preparation of these compounds and medicaments containing them
CA2041417A1 (en) Treatment of pancreatic disease with 15-keto-prostaglandin compounds
WO1999061010A3 (en) Treatment of infertility with cam-increasing compounds alone or in combination with at least one meiosis-stimulating compound
HUT50334A (en) Process for producing arylpiperazinyl-alkilenephenyl-p-heterocycluc compounds, pharmaceutically acceptable acid addition salts thereof and pharmaceutical compositions comprising the compounds as active ingredient
CA2027814A1 (en) Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
HU9500401D0 (en) 3-and 5-substituted 1,2,3,4-oxatriazole-5-iminined derivatives, a process for the preparation thereof, use of said compounos for the preparation of medicaments and pharmaceutical compositions containing said compounds
EP1714676A3 (en) Use of N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
SI1222163T1 (sl) 2'-substituirani 1,1'-bifenil-2-karboksamidi, postopek za njihovo pripravo, njihova uporaba kot zdravilo, kot tudi farmacevtski pripravki, ki jih vsebujejo
CO5170481A1 (es) Procedimiento para la preparacion de (1r,2s,4r)-(-)-2-[(2`-(n,n-dimetilamino) - etoxi)]-2-[fenil]-1,7,7-tri-[metil]-biciclo[2.2.1] heptano (deramciclano) de alta pureza y sus sales farmaceuticamente aceptables