PT1177166E - Processo de preparação de (1r,2s,4r)-(-)-2-[(2¿-{n,ndimetilamino}- etoxi)]-2-fenil-1,7,7-tri-metil-biciclo- [2.2.1]heptano e de seus sais de adição de ácido farmaceuticamente aceitáveis - Google Patents
Processo de preparação de (1r,2s,4r)-(-)-2-[(2¿-{n,ndimetilamino}- etoxi)]-2-fenil-1,7,7-tri-metil-biciclo- [2.2.1]heptano e de seus sais de adição de ácido farmaceuticamente aceitáveisInfo
- Publication number
- PT1177166E PT1177166E PT00927613T PT00927613T PT1177166E PT 1177166 E PT1177166 E PT 1177166E PT 00927613 T PT00927613 T PT 00927613T PT 00927613 T PT00927613 T PT 00927613T PT 1177166 E PT1177166 E PT 1177166E
- Authority
- PT
- Portugal
- Prior art keywords
- bicyclo
- heptane
- dimethylamino
- ethoxy
- tri
- Prior art date
Links
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/12—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9901559A HU227114B1 (en) | 1999-05-11 | 1999-05-11 | (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1177166E true PT1177166E (pt) | 2008-06-02 |
Family
ID=89998272
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00110122T PT1052243E (pt) | 1999-05-11 | 2000-05-10 | Processo para a preparacao de (1r,2s,4r)-(-)-2-¬(2'-(n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano e seus sais de adicao de acido farmaceuticamente aceitaveis |
PT00927613T PT1177166E (pt) | 1999-05-11 | 2000-05-10 | Processo de preparação de (1r,2s,4r)-(-)-2-[(2¿-{n,ndimetilamino}- etoxi)]-2-fenil-1,7,7-tri-metil-biciclo- [2.2.1]heptano e de seus sais de adição de ácido farmaceuticamente aceitáveis |
PT00110121T PT1052245E (pt) | 1999-05-11 | 2000-05-10 | (1r,2s,4r)-(-)-2-¬(2'-(n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano de elevada pureza e seus sais de adicao de acido farmaceuticamente aceitaveis processo para a preparacao destes compostos e medicamentos que os contem |
PT00929730T PT1177167E (pt) | 1999-05-11 | 2000-05-10 | (1r,2s,4r)-(-)-2-¬8'-¬n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano de elevada pureza e seus sais de adicao de acido farmaceuticamente aceitaveis e processo para a preparacao destes compostos assim como medicamentos contendo um o mais destes compostos e sua utilizacao |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00110122T PT1052243E (pt) | 1999-05-11 | 2000-05-10 | Processo para a preparacao de (1r,2s,4r)-(-)-2-¬(2'-(n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano e seus sais de adicao de acido farmaceuticamente aceitaveis |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00110121T PT1052245E (pt) | 1999-05-11 | 2000-05-10 | (1r,2s,4r)-(-)-2-¬(2'-(n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano de elevada pureza e seus sais de adicao de acido farmaceuticamente aceitaveis processo para a preparacao destes compostos e medicamentos que os contem |
PT00929730T PT1177167E (pt) | 1999-05-11 | 2000-05-10 | (1r,2s,4r)-(-)-2-¬8'-¬n,n-dimetilamino)-etoxi)|-2-¬fenil|-1,7,7-tri-¬metil|-biciclo¬2.2.1|heptano de elevada pureza e seus sais de adicao de acido farmaceuticamente aceitaveis e processo para a preparacao destes compostos assim como medicamentos contendo um o mais destes compostos e sua utilizacao |
Country Status (38)
Country | Link |
---|---|
US (3) | US6242386B1 (pt) |
EP (4) | EP1052243B1 (pt) |
JP (2) | JP4536265B2 (pt) |
KR (3) | KR100581489B1 (pt) |
CN (2) | CN1173928C (pt) |
AR (2) | AR020860A1 (pt) |
AT (4) | ATE252544T1 (pt) |
AU (2) | AU777737B2 (pt) |
BG (2) | BG64442B1 (pt) |
BR (2) | BR0010406A (pt) |
CA (2) | CA2373193A1 (pt) |
CO (1) | CO5170480A1 (pt) |
CZ (4) | CZ20014050A3 (pt) |
DE (4) | DE60006097T2 (pt) |
DK (4) | DK1052245T3 (pt) |
EA (2) | EA002164B1 (pt) |
EE (2) | EE04638B1 (pt) |
ES (4) | ES2194643T3 (pt) |
FR (2) | FR2793489B1 (pt) |
HK (2) | HK1031220A1 (pt) |
HR (2) | HRP20000290B1 (pt) |
HU (1) | HU227114B1 (pt) |
IL (4) | IL146421A0 (pt) |
IS (2) | IS2570B (pt) |
LT (2) | LT4927B (pt) |
MX (2) | MXPA01011423A (pt) |
MY (2) | MY122508A (pt) |
NO (2) | NO321486B1 (pt) |
NZ (2) | NZ515918A (pt) |
PL (2) | PL202956B1 (pt) |
PT (4) | PT1052243E (pt) |
SI (4) | SI1052243T1 (pt) |
SK (4) | SK285780B6 (pt) |
TR (2) | TR200200147T2 (pt) |
TW (2) | TWI286541B (pt) |
UA (2) | UA49974C2 (pt) |
WO (2) | WO2000068181A2 (pt) |
ZA (2) | ZA200108958B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227114B1 (en) * | 1999-05-11 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same |
US6589996B2 (en) | 2000-03-17 | 2003-07-08 | Orion Corporation | Treatment of disorders relating to the serotonergic system |
US20040082665A1 (en) * | 2001-01-22 | 2004-04-29 | Outi Maki-Ikola | Method for treating stress or tension |
HUP0103017A3 (en) * | 2001-07-18 | 2004-05-28 | Egis Gyogyszergyar Nyilvanosan | Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use |
GB0306604D0 (en) * | 2003-03-21 | 2003-04-30 | Curidium Ltd | Second medical use |
HUP0301906A3 (en) * | 2003-06-23 | 2006-03-28 | Egis Gyogyszergyar Nyilvanosan | Use of bicyclo[2.2.1]heptane derivatives for producing of pharmaceutical compositions having neuroprotectiv activity |
CZ2006623A3 (cs) * | 2004-03-12 | 2007-01-24 | Egis Gyogyszergyár Nyrt. | Kombinace deramciklanu a opioidů jako analgetik |
JP4916680B2 (ja) * | 2005-06-30 | 2012-04-18 | 株式会社半導体エネルギー研究所 | 半導体装置の作製方法、剥離方法 |
US20080258121A1 (en) * | 2007-04-23 | 2008-10-23 | Hasan Farooq | Fire Retardant Composition |
SG10201407706VA (en) | 2009-11-19 | 2015-02-27 | Yissum Res Dev Co | Novel arylated camphenes, processes for their preparation and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU179164B (en) | 1979-12-14 | 1982-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing cycloalkyl-ethers of alkanolamines |
HU212574B (en) * | 1990-09-21 | 1996-08-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing (1r,2s)-(-)-2-phenyl-(2'-dimethyl-amino-etoxy)-1,7,7-trimethyl-bicyclo[2.2.1.]heptane |
HU214588B (hu) * | 1994-07-01 | 1998-04-28 | EGIS Gyógyszergyár Rt. | Eljárás bicikloheptán-származékot tartalmazó, CCK-rendszer gátló hatású gyógyászati készítmények előállítására |
HU226061B1 (en) | 1996-10-17 | 2008-04-28 | Egis Gyogyszergyar Nyilvanosan | 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation |
HUP9900445A2 (hu) * | 1999-02-24 | 2001-06-28 | EGIS Gyógyszergyár Rt. | Eljárás (1R,2S,4R)-(-)-N,N-(dimetilamino-etoxi)-2-fenil-1,7,7-trimetil-biciklo[2.2.1]heptán előállítására és ennek köztiterméke |
HU227114B1 (en) * | 1999-05-11 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same |
-
1999
- 1999-05-11 HU HU9901559A patent/HU227114B1/hu not_active IP Right Cessation
-
2000
- 2000-05-10 AR ARP000102244A patent/AR020860A1/es not_active Application Discontinuation
- 2000-05-10 DK DK00110121T patent/DK1052245T3/da active
- 2000-05-10 HR HR20000290A patent/HRP20000290B1/xx not_active IP Right Cessation
- 2000-05-10 CO CO00033730A patent/CO5170480A1/es not_active Application Discontinuation
- 2000-05-10 DE DE60006097T patent/DE60006097T2/de not_active Expired - Lifetime
- 2000-05-10 EP EP00110122A patent/EP1052243B1/en not_active Expired - Lifetime
- 2000-05-10 SK SK1624-2001A patent/SK285780B6/sk not_active IP Right Cessation
- 2000-05-10 PT PT00110122T patent/PT1052243E/pt unknown
- 2000-05-10 TR TR2002/00147T patent/TR200200147T2/xx unknown
- 2000-05-10 FR FR0005940A patent/FR2793489B1/fr not_active Expired - Fee Related
- 2000-05-10 SI SI200030219T patent/SI1052243T1/xx unknown
- 2000-05-10 HR HR20000291A patent/HRP20000291B1/xx not_active IP Right Cessation
- 2000-05-10 EE EEP200100595A patent/EE04638B1/xx not_active IP Right Cessation
- 2000-05-10 UA UA2000052641A patent/UA49974C2/uk unknown
- 2000-05-10 DK DK00929730T patent/DK1177167T3/da active
- 2000-05-10 ES ES00110121T patent/ES2194643T3/es not_active Expired - Lifetime
- 2000-05-10 BR BR0010406-0A patent/BR0010406A/pt not_active Application Discontinuation
- 2000-05-10 DE DE60002117T patent/DE60002117T2/de not_active Expired - Lifetime
- 2000-05-10 PL PL340108A patent/PL202956B1/pl not_active IP Right Cessation
- 2000-05-10 MX MXPA01011423A patent/MXPA01011423A/es active IP Right Grant
- 2000-05-10 SI SI200030989T patent/SI1177166T1/sl unknown
- 2000-05-10 CZ CZ20014050A patent/CZ20014050A3/cs unknown
- 2000-05-10 ES ES00929730T patent/ES2208328T3/es not_active Expired - Lifetime
- 2000-05-10 BG BG104416A patent/BG64442B1/bg unknown
- 2000-05-10 PL PL00340107A patent/PL340107A1/xx not_active IP Right Cessation
- 2000-05-10 FR FR0005941A patent/FR2793490B1/fr not_active Expired - Fee Related
- 2000-05-10 EP EP00110121A patent/EP1052245B1/en not_active Expired - Lifetime
- 2000-05-10 DK DK00110122T patent/DK1052243T3/da active
- 2000-05-10 JP JP2000617164A patent/JP4536265B2/ja not_active Expired - Fee Related
- 2000-05-10 NZ NZ515918A patent/NZ515918A/xx not_active IP Right Cessation
- 2000-05-10 DE DE60004126T patent/DE60004126T2/de not_active Expired - Fee Related
- 2000-05-10 NZ NZ515917A patent/NZ515917A/xx unknown
- 2000-05-10 UA UA2000052642A patent/UA61122C2/uk unknown
- 2000-05-10 AT AT00929730T patent/ATE252544T1/de not_active IP Right Cessation
- 2000-05-10 ES ES00927613T patent/ES2302694T3/es not_active Expired - Lifetime
- 2000-05-10 AT AT00110121T patent/ATE237579T1/de not_active IP Right Cessation
- 2000-05-10 DE DE60038112T patent/DE60038112T8/de not_active Expired - Fee Related
- 2000-05-10 MY MYPI20002033A patent/MY122508A/en unknown
- 2000-05-10 DK DK00927613T patent/DK1177166T3/da active
- 2000-05-10 EA EA200000411A patent/EA002164B1/ru not_active IP Right Cessation
- 2000-05-10 US US09/569,050 patent/US6242386B1/en not_active Expired - Fee Related
- 2000-05-10 TW TW089108901A patent/TWI286541B/zh not_active IP Right Cessation
- 2000-05-10 KR KR1020017014355A patent/KR100581489B1/ko not_active IP Right Cessation
- 2000-05-10 AU AU47731/00A patent/AU777737B2/en not_active Ceased
- 2000-05-10 AU AU46003/00A patent/AU776696B2/en not_active Ceased
- 2000-05-10 CA CA002373193A patent/CA2373193A1/en not_active Abandoned
- 2000-05-10 AT AT00927613T patent/ATE386714T1/de not_active IP Right Cessation
- 2000-05-10 EE EEP200100596A patent/EE200100596A/xx not_active IP Right Cessation
- 2000-05-10 CZ CZ20001723A patent/CZ291329B6/cs not_active IP Right Cessation
- 2000-05-10 SK SK1623-2001A patent/SK285635B6/sk not_active IP Right Cessation
- 2000-05-10 ES ES00110122T patent/ES2203373T3/es not_active Expired - Lifetime
- 2000-05-10 SI SI200030292T patent/SI1177167T1/xx unknown
- 2000-05-10 WO PCT/HU2000/000043 patent/WO2000068181A2/en active IP Right Grant
- 2000-05-10 EP EP00927613A patent/EP1177166B1/en not_active Expired - Lifetime
- 2000-05-10 CZ CZ20014051A patent/CZ20014051A3/cs unknown
- 2000-05-10 PT PT00927613T patent/PT1177166E/pt unknown
- 2000-05-10 MX MXPA01011420A patent/MXPA01011420A/es active IP Right Grant
- 2000-05-10 KR KR1020017014354A patent/KR100685071B1/ko not_active IP Right Cessation
- 2000-05-10 CN CNB008082391A patent/CN1173928C/zh not_active Expired - Fee Related
- 2000-05-10 KR KR1020067001294A patent/KR20060010874A/ko not_active Application Discontinuation
- 2000-05-10 SK SK689-2000A patent/SK6892000A3/sk unknown
- 2000-05-10 JP JP2000617162A patent/JP4031203B2/ja not_active Expired - Fee Related
- 2000-05-10 CN CNB008083576A patent/CN1325465C/zh not_active Expired - Fee Related
- 2000-05-10 AT AT00110122T patent/ATE246170T1/de not_active IP Right Cessation
- 2000-05-10 TW TW089108902A patent/TW528742B/zh not_active IP Right Cessation
- 2000-05-10 AR ARP000102239A patent/AR023900A1/es active IP Right Grant
- 2000-05-10 SK SK690-2000A patent/SK6902000A3/sk unknown
- 2000-05-10 IL IL14642100A patent/IL146421A0/xx active IP Right Grant
- 2000-05-10 MY MYPI20002032A patent/MY123523A/en unknown
- 2000-05-10 SI SI200030124T patent/SI1052245T1/xx unknown
- 2000-05-10 WO PCT/HU2000/000044 patent/WO2000068183A2/en not_active Application Discontinuation
- 2000-05-10 TR TR2002/00148T patent/TR200200148T2/xx unknown
- 2000-05-10 US US09/569,046 patent/US6335469B1/en not_active Expired - Lifetime
- 2000-05-10 EP EP00929730A patent/EP1177167B1/en not_active Expired - Lifetime
- 2000-05-10 BR BR0010412-4A patent/BR0010412A/pt not_active Application Discontinuation
- 2000-05-10 PT PT00110121T patent/PT1052245E/pt unknown
- 2000-05-10 CA CA2369393A patent/CA2369393C/en not_active Expired - Fee Related
- 2000-05-10 PT PT00929730T patent/PT1177167E/pt unknown
- 2000-05-10 CZ CZ20001722A patent/CZ290734B6/cs not_active IP Right Cessation
- 2000-05-10 BG BG104417A patent/BG64673B1/bg unknown
- 2000-05-10 IL IL14642000A patent/IL146420A0/xx active IP Right Grant
- 2000-05-10 EA EA200000410A patent/EA002163B1/ru not_active IP Right Cessation
- 2000-12-14 HK HK00108103A patent/HK1031220A1/xx not_active IP Right Cessation
-
2001
- 2001-01-27 HK HK01100582A patent/HK1031372A1/xx not_active IP Right Cessation
- 2001-10-30 ZA ZA200108958A patent/ZA200108958B/en unknown
- 2001-10-30 US US09/984,542 patent/US6624201B2/en not_active Expired - Lifetime
- 2001-10-30 ZA ZA200108956A patent/ZA200108956B/en unknown
- 2001-10-31 NO NO20015336A patent/NO321486B1/no not_active IP Right Cessation
- 2001-11-01 NO NO20015352A patent/NO321487B1/no unknown
- 2001-11-08 LT LT2001109A patent/LT4927B/lt not_active IP Right Cessation
- 2001-11-08 LT LT2001108A patent/LT4928B/lt not_active IP Right Cessation
- 2001-11-09 IS IS6153A patent/IS2570B/is unknown
- 2001-11-09 IS IS6152A patent/IS6152A/is unknown
- 2001-11-11 IL IL146420A patent/IL146420A/en not_active IP Right Cessation
- 2001-11-11 IL IL146421A patent/IL146421A/en not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EG24142A (en) | Crystalline monohydrate, process for the preparation thereof and the use thereof for preparing a pharmaceutical composition | |
HK1050370A1 (en) | Process for preparing 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives. | |
PL354322A1 (en) | 2'-substituted 1,1'-biphenyl-2-carbonamides, method for the production thereof, use thereof as a medicament and pharmaceutical preparations containing said compounds | |
PT1177166E (pt) | Processo de preparação de (1r,2s,4r)-(-)-2-[(2¿-{n,ndimetilamino}- etoxi)]-2-fenil-1,7,7-tri-metil-biciclo- [2.2.1]heptano e de seus sais de adição de ácido farmaceuticamente aceitáveis | |
SI1279665T1 (sl) | Postopek za pripravo perindoprila, njegovih analogov in njegovih soli, z uporabo 2,5-diokso-oksazolidin-intermediatnih spojin | |
HUP0200144A3 (en) | Process for preparing pesticidal 5-amino-1-aryl-3 cyanopyrazole derivatives, and the new intermediates | |
HUP0101263A3 (en) | Process for producing optically active threo-3-amino-1,2-epoxy compounds | |
HK1061843A1 (en) | Process for cis-1-(2-(4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronape ethyl) pyrrolidine | |
HUP0102447A3 (en) | Novel octahydro-6,10-dioxo-6h-pyridazino/1,2a//1,2/diazepin-1-carboxylic acid derivatives, preparation method and use for preparing therapeutically active compounds | |
AU2000262086A1 (en) | Process for making a (3r,3'r)-zeaxanthin precursor | |
AU3182300A (en) | Process for the preparation of (1r, 2s, 4r) -(-) -2 - (2 -dimethylaminoethoxy) -2 -phenyl -1,7,7 - trimethylbicyclo (2.2.1) heptane | |
PL347658A1 (en) | Vancoresmycin, a process for its production and its use as a pharmaceutical | |
PL347025A1 (en) | Process for preparing 1,5−diaryl−3−substituted pyrazoles | |
HUP0102370A3 (en) | Mumbaistatin, a process for its production and its use as a pharmaceutical | |
HU0001417D0 (en) | New pharmaceutically applicable salts, process for their production and medicaments containing them | |
HUP0000982A2 (en) | Process for the preparation of 1,1-dioxo-penicillanic acid derivatives | |
IL146810A0 (en) | Process for preparing 10, 11-methanobenzosuberane derivatives | |
IL137364A0 (en) | A process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol | |
HUP0203129A3 (en) | Aromatic di-keto derivatives, process for producing them and use them as pharmaceuticals | |
AU5848400A (en) | Novel physiologically active substance, process for producing the same and use thereof | |
AU2003272019A1 (en) | Process for preparing a pharmaceutically active compound and for preparing its intermediate | |
HUP0201873A3 (en) | Process for preparing (-)-(1s,4r) n-protected 4-amino-2-cyclopentene-1-carboxylate esters and the intermediate | |
EP1186588A4 (en) | 6-HYDROXY-2-NAPHTYLCARBINOL AND A METHOD FOR THE PRODUCTION THEREOF | |
HK1031881A1 (en) | Process for preparing 8-cyclopentyl-6-ethyl-3-Äsu bstitutedÜ-5,8-dihydro-4H-1,2,3A, 7,8-pentaaza-as-indacenes and intermediates useful therein. | |
EG22464A (en) | Process for making 1,3-disubstituted-4-oxocyclic ureas |