SE466205B - 7-/2-(5-amino-1,2,4-tiadiazol-3-yl)-2-(substituerad) iminoacetamid/-3-/3-(kvaternaer ammonio)-1-propen-1-yl/-3-cefem-4-karboxylater - Google Patents

7-/2-(5-amino-1,2,4-tiadiazol-3-yl)-2-(substituerad) iminoacetamid/-3-/3-(kvaternaer ammonio)-1-propen-1-yl/-3-cefem-4-karboxylater

Info

Publication number
SE466205B
SE466205B SE8501680A SE8501680A SE466205B SE 466205 B SE466205 B SE 466205B SE 8501680 A SE8501680 A SE 8501680A SE 8501680 A SE8501680 A SE 8501680A SE 466205 B SE466205 B SE 466205B
Authority
SE
Sweden
Prior art keywords
lower alkyl
amino
thiadiazol
hydroxy
cephem
Prior art date
Application number
SE8501680A
Other languages
English (en)
Swedish (sv)
Other versions
SE8501680D0 (sv
SE8501680L (sv
Inventor
M Oka
H Yamashita
T Naito
J Okumura
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of SE8501680D0 publication Critical patent/SE8501680D0/xx
Publication of SE8501680L publication Critical patent/SE8501680L/xx
Publication of SE466205B publication Critical patent/SE466205B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE8501680A 1984-04-09 1985-04-03 7-/2-(5-amino-1,2,4-tiadiazol-3-yl)-2-(substituerad) iminoacetamid/-3-/3-(kvaternaer ammonio)-1-propen-1-yl/-3-cefem-4-karboxylater SE466205B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (3)

Publication Number Publication Date
SE8501680D0 SE8501680D0 (sv) 1985-04-03
SE8501680L SE8501680L (sv) 1985-10-10
SE466205B true SE466205B (sv) 1992-01-13

Family

ID=24393575

Family Applications (4)

Application Number Title Priority Date Filing Date
SE8501680A SE466205B (sv) 1984-04-09 1985-04-03 7-/2-(5-amino-1,2,4-tiadiazol-3-yl)-2-(substituerad) iminoacetamid/-3-/3-(kvaternaer ammonio)-1-propen-1-yl/-3-cefem-4-karboxylater
SE8901224A SE470259B (sv) 1984-04-09 1989-04-06 Mellanprodukter till cefalosporiner
SE8901225A SE505256C2 (sv) 1984-04-09 1989-04-06 Nya 7-amino cefalosporinderivat med en kvaternär ammoniogrupp samt förfarande för framställning därav
SE8901226A SE470260B (sv) 1984-04-09 1989-04-06 Mellanprodukter till cefolosporiner

Family Applications After (3)

Application Number Title Priority Date Filing Date
SE8901224A SE470259B (sv) 1984-04-09 1989-04-06 Mellanprodukter till cefalosporiner
SE8901225A SE505256C2 (sv) 1984-04-09 1989-04-06 Nya 7-amino cefalosporinderivat med en kvaternär ammoniogrupp samt förfarande för framställning därav
SE8901226A SE470260B (sv) 1984-04-09 1989-04-06 Mellanprodukter till cefolosporiner

Country Status (31)

Country Link
JP (4) JPS615084A (fi)
KR (1) KR870002166B1 (fi)
AR (1) AR244694A1 (fi)
AT (1) AT388735B (fi)
AU (2) AU580990B2 (fi)
BE (1) BE902148A (fi)
CA (3) CA1276929C (fi)
CH (1) CH669197A5 (fi)
DD (3) DD236735A5 (fi)
DE (1) DE3512225A1 (fi)
DK (1) DK155985A (fi)
ES (4) ES8607318A1 (fi)
FI (1) FI84830C (fi)
FR (1) FR2563832B1 (fi)
GB (3) GB2157293B (fi)
GR (1) GR850883B (fi)
HU (2) HU204277B (fi)
IE (2) IE58408B1 (fi)
IL (1) IL74826A (fi)
IT (1) IT1190353B (fi)
LU (1) LU85840A1 (fi)
MY (1) MY101940A (fi)
NL (1) NL192925C (fi)
NZ (1) NZ211659A (fi)
OA (1) OA07985A (fi)
PT (1) PT80246B (fi)
RU (1) RU2056425C1 (fi)
SE (4) SE466205B (fi)
SU (4) SU1487814A3 (fi)
YU (2) YU46151B (fi)
ZA (1) ZA852236B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
EP0764648B1 (en) * 1988-03-16 2002-01-16 Eisai Co., Ltd. Cephem derivatives and process for the preparation thereof
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
WO1996005205A1 (fr) * 1994-08-16 1996-02-22 Meiji Seika Kabushiki Kaisha Nouveau derive de cepheme
EP1090013A1 (en) 1998-06-22 2001-04-11 F. Hoffmann-La Roche Ag Propenyl cephalosporin derivatives
US7507812B2 (en) 2003-09-09 2009-03-24 Nippon Chemical Industrial Co., Ltd. Process for producing 3-chloromethyl-3-cephem derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (fi) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (fi) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
GB2194790A (en) 1988-03-16
NL8501002A (nl) 1985-11-01
JPS61143387A (ja) 1986-07-01
PT80246A (en) 1985-05-01
GR850883B (fi) 1985-11-25
FR2563832A1 (fr) 1985-11-08
ES551550A0 (es) 1987-06-01
ES8607318A1 (es) 1986-06-16
YU46151B (sh) 1993-05-28
PT80246B (pt) 1987-10-20
HUT37622A (en) 1986-01-23
SE8901225L (sv) 1989-04-06
IL74826A (en) 1990-01-18
GB2157293B (en) 1988-10-05
ES557060A0 (es) 1987-12-01
IT1190353B (it) 1988-02-16
FI851379L (fi) 1985-10-10
GB8721346D0 (en) 1987-10-14
GB8508846D0 (en) 1985-05-09
JPH0350754B2 (fi) 1991-08-02
JPH0351716B2 (fi) 1991-08-07
SE8501680D0 (sv) 1985-04-03
GB2194789A (en) 1988-03-16
IL74826A0 (en) 1985-07-31
FI84830B (fi) 1991-10-15
FI851379A0 (fi) 1985-04-04
ES551551A0 (es) 1987-07-01
SE8901226D0 (sv) 1989-04-06
SE8901226L (sv) 1989-04-06
GB8721347D0 (en) 1987-10-14
HU204277B (en) 1991-12-30
ATA103985A (de) 1989-01-15
IE58408B1 (en) 1993-09-22
FR2563832B1 (fr) 1989-08-18
GB2194790B (en) 1988-10-05
SE8901225D0 (sv) 1989-04-06
YU46213B (sh) 1993-05-28
CA1340672C (en) 1999-07-20
ES8706694A1 (es) 1987-07-01
YU118987A (en) 1988-10-31
YU60085A (en) 1987-12-31
OA07985A (fr) 1987-01-31
SU1487814A3 (ru) 1989-06-15
SE470260B (sv) 1993-12-20
AU4086285A (en) 1985-10-17
SU1436882A3 (ru) 1988-11-07
GB2157293A (en) 1985-10-23
CA1340638C (en) 1999-07-06
AT388735B (de) 1989-08-25
DD249024A5 (de) 1987-08-26
AR244694A1 (es) 1993-11-30
KR850007424A (ko) 1985-12-04
IE58403B1 (en) 1993-09-22
ES8706155A1 (es) 1987-06-01
ES8800949A1 (es) 1987-12-01
SE8901224D0 (sv) 1989-04-06
SE8501680L (sv) 1985-10-10
DK155985A (da) 1985-10-10
JPH0262557B2 (fi) 1990-12-26
KR870002166B1 (ko) 1987-12-14
FI84830C (fi) 1992-01-27
SU1367858A3 (ru) 1988-01-15
DK155985D0 (da) 1985-04-03
RU2056425C1 (ru) 1996-03-20
ZA852236B (en) 1985-11-27
JPH0357106B2 (fi) 1991-08-30
DE3512225C2 (fi) 1990-02-22
SE505256C2 (sv) 1997-07-21
JPS615084A (ja) 1986-01-10
GB2194789B (en) 1988-10-12
BE902148A (fr) 1985-10-09
AU610278B2 (en) 1991-05-16
JPS61143391A (ja) 1986-07-01
MY101940A (en) 1992-02-15
IT8520267A0 (it) 1985-04-05
IE850866L (en) 1985-10-09
SU1375140A3 (ru) 1988-02-15
DD236735A5 (de) 1986-06-18
SE8901224L (sv) 1989-04-06
HU193750B (en) 1987-11-30
NL192925B (nl) 1998-01-05
AU2504188A (en) 1989-03-02
SE470259B (sv) 1993-12-20
ES542013A0 (es) 1986-06-16
DE3512225A1 (de) 1985-10-17
JPS61143390A (ja) 1986-07-01
AU580990B2 (en) 1989-02-09
LU85840A1 (fr) 1985-12-16
CH669197A5 (de) 1989-02-28
DD251752A5 (de) 1987-11-25
CA1276929C (en) 1990-11-27
NZ211659A (en) 1988-11-29
NL192925C (nl) 1998-05-07

Similar Documents

Publication Publication Date Title
SE466205B (sv) 7-/2-(5-amino-1,2,4-tiadiazol-3-yl)-2-(substituerad) iminoacetamid/-3-/3-(kvaternaer ammonio)-1-propen-1-yl/-3-cefem-4-karboxylater
US4486586A (en) Cephalosporin derivatives
US4839350A (en) Cephalosporin compounds and the production thereof
HU177441B (en) Process for preparing syn isomers of 3,7-disubstituted 3-cephem-4-carboxylic acid derivatives
EP0184227B1 (en) 2-oxymino 2-aminothiazolyl acetic acid derivatives and processes for preparation thereof
SE450384B (sv) Nya cefemforeningar och forfarande for deras framstellning
US4751295A (en) Cephalosporin derivatives
FI73688B (fi) Foerfarande foer framstaellning av farmakologiskt verksamma 7-/2-(4-tiazolyl)-2-oxiimino-acetamido/-3- cefem-4-karboxylsyraderivats syn-isomerer.
NO172893B (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive cefem-forbindelser
KR930007416B1 (ko) 3-(치환된)프로페닐아미노 티아졸릴 세팔로스포란산 및 그 에스텔의 제조방법
AU690482B2 (en) Process for producing cephalosporin antibiotics
JPS61178991A (ja) 新規セフアロスポリン化合物
CA1340609C (en) Cephalosporin derivatives
JP2605096B2 (ja) セフェム誘導体
RU2081874C1 (ru) Соединения цефема и их фармацевтически приемлемые соли
JPS60209589A (ja) セフアロスポリン誘導体のエステル
CZ286386B6 (cs) 3-Cefem-4-karboxylátové deriváty, způsob jejich přípravy, a farmaceutický prostředek, který je obsahuje
JPS62195386A (ja) ７−チアジアゾリルアセトアミド−３−セフエム誘導体
JPS6127991A (ja) セフアロスポリン誘導体その製造法およびそれを有効成分とする抗菌剤
JPS6388187A (ja) ３−アンモニオプロペニルセフエム誘導体

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8501680-6

Format of ref document f/p: F

NUG Patent has lapsed