GB2194789B - Antibacterial agent intermediates - Google Patents

Antibacterial agent intermediates

Info

Publication number
GB2194789B
GB2194789B GB08721346A GB8721346A GB2194789B GB 2194789 B GB2194789 B GB 2194789B GB 08721346 A GB08721346 A GB 08721346A GB 8721346 A GB8721346 A GB 8721346A GB 2194789 B GB2194789 B GB 2194789B
Authority
GB
United Kingdom
Prior art keywords
antibacterial agent
agent intermediates
intermediates
antibacterial
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08721346A
Other versions
GB8721346D0 (en
GB2194789A (en
Inventor
Haruhiro Yamashita
Masahisa Oka
Takayuki Naito
Jun Okumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB8721346D0 publication Critical patent/GB8721346D0/en
Publication of GB2194789A publication Critical patent/GB2194789A/en
Application granted granted Critical
Publication of GB2194789B publication Critical patent/GB2194789B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB08721346A 1984-04-09 1987-09-10 Antibacterial agent intermediates Expired GB2194789B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (3)

Publication Number Publication Date
GB8721346D0 GB8721346D0 (en) 1987-10-14
GB2194789A GB2194789A (en) 1988-03-16
GB2194789B true GB2194789B (en) 1988-10-12

Family

ID=24393575

Family Applications (3)

Application Number Title Priority Date Filing Date
GB08508846A Expired GB2157293B (en) 1984-04-09 1985-04-04 Chemical compounds
GB08721347A Expired GB2194790B (en) 1984-04-09 1987-09-10 Intermediates useful for preparing antibacterial agents
GB08721346A Expired GB2194789B (en) 1984-04-09 1987-09-10 Antibacterial agent intermediates

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB08508846A Expired GB2157293B (en) 1984-04-09 1985-04-04 Chemical compounds
GB08721347A Expired GB2194790B (en) 1984-04-09 1987-09-10 Intermediates useful for preparing antibacterial agents

Country Status (31)

Country Link
JP (4) JPS615084A (en)
KR (1) KR870002166B1 (en)
AR (1) AR244694A1 (en)
AT (1) AT388735B (en)
AU (2) AU580990B2 (en)
BE (1) BE902148A (en)
CA (3) CA1276929C (en)
CH (1) CH669197A5 (en)
DD (3) DD249024A5 (en)
DE (1) DE3512225A1 (en)
DK (1) DK155985A (en)
ES (4) ES8607318A1 (en)
FI (1) FI84830C (en)
FR (1) FR2563832B1 (en)
GB (3) GB2157293B (en)
GR (1) GR850883B (en)
HU (2) HU193750B (en)
IE (2) IE58408B1 (en)
IL (1) IL74826A (en)
IT (1) IT1190353B (en)
LU (1) LU85840A1 (en)
MY (1) MY101940A (en)
NL (1) NL192925C (en)
NZ (1) NZ211659A (en)
OA (1) OA07985A (en)
PT (1) PT80246B (en)
RU (1) RU2056425C1 (en)
SE (4) SE466205B (en)
SU (4) SU1375140A3 (en)
YU (2) YU46151B (en)
ZA (1) ZA852236B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (en) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd Novel cephem compound and preparation thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
DE3650157T2 (en) * 1985-12-26 1995-05-04 Eisai Co Ltd CEPHALOSPORINE COMPOUNDS.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (en) * 1986-11-06 1996-01-24 エーザイ株式会社 3-propenyl cephem derivative
FR2622585B1 (en) * 1987-11-03 1991-04-19 Roussel Uclaf NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A SUBSTITUTED VINYL RADICAL, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED
JPH0699449B2 (en) * 1988-03-16 1994-12-07 エーザイ株式会社 Synthetic intermediate of cephem derivative
EP0612751A3 (en) * 1988-03-16 1994-09-21 Eisai Co Ltd Compounds for the preparation of cephem derivatives.
FR2655042B1 (en) * 1989-11-29 1994-01-21 Adir Cie NOVEL SUBSTITUTED BENZOTHIAZOLINONES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2663332B1 (en) * 1990-06-15 1997-11-07 Roussel Uclaf NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A RADICAL PROPENYL SUBSTITUTED BY A QUATERNARY AMMONIUM, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (en) * 1991-08-21 1993-06-25 Biochemie Gmbh NEW PROCESS AND NEW INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
JPH0741484A (en) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk Cephem compound and antimicrobial agent
US5661144A (en) * 1994-08-16 1997-08-26 Meiji Seika Kabushiki Kaisha Cephem derivatives with 3-substituted bis heterocycles
PL345266A1 (en) 1998-06-22 2001-12-03 Hoffmann La Roche Propenyl cephalosporin derivatives
EP1666483B1 (en) 2003-09-09 2011-08-17 Nippon Chemical Industrial Company Limited Process for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (en) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (en) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (en) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
SE470260B (en) 1993-12-20
FI84830C (en) 1992-01-27
GB8721347D0 (en) 1987-10-14
SE8901225D0 (en) 1989-04-06
BE902148A (en) 1985-10-09
IE58403B1 (en) 1993-09-22
ZA852236B (en) 1985-11-27
IT1190353B (en) 1988-02-16
DE3512225A1 (en) 1985-10-17
NL192925B (en) 1998-01-05
YU118987A (en) 1988-10-31
PT80246A (en) 1985-05-01
SE8501680D0 (en) 1985-04-03
YU46213B (en) 1993-05-28
NL192925C (en) 1998-05-07
DD249024A5 (en) 1987-08-26
RU2056425C1 (en) 1996-03-20
JPH0350754B2 (en) 1991-08-02
HU193750B (en) 1987-11-30
NZ211659A (en) 1988-11-29
ES542013A0 (en) 1986-06-16
DD251752A5 (en) 1987-11-25
ES8800949A1 (en) 1987-12-01
KR870002166B1 (en) 1987-12-14
SE8901224D0 (en) 1989-04-06
SE8901226L (en) 1989-04-06
SE8501680L (en) 1985-10-10
LU85840A1 (en) 1985-12-16
ES551550A0 (en) 1987-06-01
KR850007424A (en) 1985-12-04
JPH0351716B2 (en) 1991-08-07
FI84830B (en) 1991-10-15
AU580990B2 (en) 1989-02-09
DD236735A5 (en) 1986-06-18
GB2157293B (en) 1988-10-05
SE470259B (en) 1993-12-20
JPH0262557B2 (en) 1990-12-26
AR244694A1 (en) 1993-11-30
IE58408B1 (en) 1993-09-22
OA07985A (en) 1987-01-31
ES557060A0 (en) 1987-12-01
GR850883B (en) 1985-11-25
ES8607318A1 (en) 1986-06-16
NL8501002A (en) 1985-11-01
FR2563832B1 (en) 1989-08-18
MY101940A (en) 1992-02-15
GB8721346D0 (en) 1987-10-14
PT80246B (en) 1987-10-20
JPS615084A (en) 1986-01-10
SU1436882A3 (en) 1988-11-07
GB8508846D0 (en) 1985-05-09
IE850866L (en) 1985-10-09
ES551551A0 (en) 1987-07-01
FI851379L (en) 1985-10-10
GB2194790A (en) 1988-03-16
SE505256C2 (en) 1997-07-21
GB2194790B (en) 1988-10-05
YU46151B (en) 1993-05-28
IT8520267A0 (en) 1985-04-05
HU204277B (en) 1991-12-30
AU610278B2 (en) 1991-05-16
IL74826A0 (en) 1985-07-31
CH669197A5 (en) 1989-02-28
IL74826A (en) 1990-01-18
SU1367858A3 (en) 1988-01-15
AU2504188A (en) 1989-03-02
GB2194789A (en) 1988-03-16
GB2157293A (en) 1985-10-23
SE8901225L (en) 1989-04-06
SE466205B (en) 1992-01-13
SE8901226D0 (en) 1989-04-06
FI851379A0 (en) 1985-04-04
JPH0357106B2 (en) 1991-08-30
FR2563832A1 (en) 1985-11-08
AT388735B (en) 1989-08-25
JPS61143390A (en) 1986-07-01
CA1276929C (en) 1990-11-27
HUT37622A (en) 1986-01-23
CA1340638C (en) 1999-07-06
SU1375140A3 (en) 1988-02-15
SE8901224L (en) 1989-04-06
YU60085A (en) 1987-12-31
JPS61143387A (en) 1986-07-01
DE3512225C2 (en) 1990-02-22
ATA103985A (en) 1989-01-15
ES8706694A1 (en) 1987-07-01
CA1340672C (en) 1999-07-20
JPS61143391A (en) 1986-07-01
SU1487814A3 (en) 1989-06-15
AU4086285A (en) 1985-10-17
DK155985A (en) 1985-10-10
ES8706155A1 (en) 1987-06-01
DK155985D0 (en) 1985-04-03

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20050403