CA1276929C - Cephalosporin antibacterial agents - Google Patents
Cephalosporin antibacterial agentsInfo
- Publication number
- CA1276929C CA1276929C CA000474260A CA474260A CA1276929C CA 1276929 C CA1276929 C CA 1276929C CA 000474260 A CA000474260 A CA 000474260A CA 474260 A CA474260 A CA 474260A CA 1276929 C CA1276929 C CA 1276929C
- Authority
- CA
- Canada
- Prior art keywords
- amino
- alkyl
- cephem
- thiadiazol
- carboxylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA000615909A CA1340609C (en) | 1984-04-09 | 1990-10-25 | Cephalosporin derivatives |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59794184A | 1984-04-09 | 1984-04-09 | |
US597,941 | 1984-04-09 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000615909A Division CA1340609C (en) | 1984-04-09 | 1990-10-25 | Cephalosporin derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1276929C true CA1276929C (en) | 1990-11-27 |
Family
ID=24393575
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000474260A Expired - Lifetime CA1276929C (en) | 1984-04-09 | 1985-02-14 | Cephalosporin antibacterial agents |
CA000616143A Expired - Fee Related CA1340638C (en) | 1984-04-09 | 1991-08-12 | Cephalosporin derivatives |
CA000616144A Expired - Fee Related CA1340672C (en) | 1984-04-09 | 1991-08-21 | Cephalosporin derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000616143A Expired - Fee Related CA1340638C (en) | 1984-04-09 | 1991-08-12 | Cephalosporin derivatives |
CA000616144A Expired - Fee Related CA1340672C (en) | 1984-04-09 | 1991-08-21 | Cephalosporin derivatives |
Country Status (31)
Country | Link |
---|---|
JP (4) | JPS615084A (fi) |
KR (1) | KR870002166B1 (fi) |
AR (1) | AR244694A1 (fi) |
AT (1) | AT388735B (fi) |
AU (2) | AU580990B2 (fi) |
BE (1) | BE902148A (fi) |
CA (3) | CA1276929C (fi) |
CH (1) | CH669197A5 (fi) |
DD (3) | DD249024A5 (fi) |
DE (1) | DE3512225A1 (fi) |
DK (1) | DK155985A (fi) |
ES (4) | ES8607318A1 (fi) |
FI (1) | FI84830C (fi) |
FR (1) | FR2563832B1 (fi) |
GB (3) | GB2157293B (fi) |
GR (1) | GR850883B (fi) |
HU (2) | HU193750B (fi) |
IE (2) | IE58408B1 (fi) |
IL (1) | IL74826A (fi) |
IT (1) | IT1190353B (fi) |
LU (1) | LU85840A1 (fi) |
MY (1) | MY101940A (fi) |
NL (1) | NL192925C (fi) |
NZ (1) | NZ211659A (fi) |
OA (1) | OA07985A (fi) |
PT (1) | PT80246B (fi) |
RU (1) | RU2056425C1 (fi) |
SE (4) | SE466205B (fi) |
SU (4) | SU1487814A3 (fi) |
YU (2) | YU46151B (fi) |
ZA (1) | ZA852236B (fi) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61145186A (ja) * | 1984-12-20 | 1986-07-02 | Meiji Seika Kaisha Ltd | 新規セフエム化合物及びその製造法 |
US4708955A (en) * | 1985-06-24 | 1987-11-24 | Bristol-Myers Company | 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof |
ATE114657T1 (de) * | 1985-12-26 | 1994-12-15 | Eisai Co Ltd | Cephalosporin-verbindungen. |
IL84128A (en) * | 1986-10-13 | 1992-12-01 | Eisai Co Ltd | 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them |
AU614723B2 (en) * | 1986-10-13 | 1991-09-12 | Eisai Co. Ltd. | 3-propenylcephem derivative |
JPH085897B2 (ja) * | 1986-11-06 | 1996-01-24 | エーザイ株式会社 | 3−プロペニルセフェム誘導体 |
FR2622585B1 (fr) * | 1987-11-03 | 1991-04-19 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
JPH0699449B2 (ja) * | 1988-03-16 | 1994-12-07 | エーザイ株式会社 | セフェム誘導体の合成中間体 |
CN1022837C (zh) * | 1988-03-16 | 1993-11-24 | 卫材株式会社 | 制备头孢烯衍生物的方法 |
FR2655042B1 (fr) * | 1989-11-29 | 1994-01-21 | Adir Cie | Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2663332B1 (fr) * | 1990-06-15 | 1997-11-07 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus. |
US5126336A (en) * | 1990-08-23 | 1992-06-30 | Bristol-Myers Squibb Company | Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof |
AT396108B (de) * | 1991-08-21 | 1993-06-25 | Biochemie Gmbh | Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten |
JPH0741484A (ja) * | 1993-07-29 | 1995-02-10 | Katayama Seiyakushiyo:Kk | セフェム化合物及び抗菌剤 |
EP0723966A4 (en) * | 1994-08-16 | 1997-01-29 | Meiji Seika Co | NEW DERIVATIVES FROM CEPHEM |
CN1173979C (zh) | 1998-06-22 | 2004-11-03 | 巴斯利尔药物股份公司 | 丙烯基头孢茵素衍生物 |
US7507812B2 (en) | 2003-09-09 | 2009-03-24 | Nippon Chemical Industrial Co., Ltd. | Process for producing 3-chloromethyl-3-cephem derivatives |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1342241A (en) * | 1970-01-23 | 1974-01-03 | Glaxo Lab Ltd | Cephalosporin compounds |
US4390534A (en) * | 1978-12-29 | 1983-06-28 | Fujisawa Pharmaceutical Co., Ltd. | Cephem and cepham compounds |
EP0025017A1 (de) * | 1979-08-28 | 1981-03-11 | Ciba-Geigy Ag | Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren |
US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
GR75644B (fi) * | 1980-06-18 | 1984-08-02 | Fujisawa Pharmaceutical Co | |
GR78245B (fi) * | 1980-09-12 | 1984-09-26 | Ciba Geigy Ag | |
US4521413A (en) * | 1981-09-14 | 1985-06-04 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4486586A (en) * | 1983-02-10 | 1984-12-04 | Bristol-Myers Company | Cephalosporin derivatives |
-
1985
- 1985-02-14 CA CA000474260A patent/CA1276929C/en not_active Expired - Lifetime
- 1985-03-25 ZA ZA852236A patent/ZA852236B/xx unknown
- 1985-04-02 AR AR85299945A patent/AR244694A1/es active
- 1985-04-02 NZ NZ211659A patent/NZ211659A/xx unknown
- 1985-04-03 DD DD85287524A patent/DD249024A5/de unknown
- 1985-04-03 DK DK155985A patent/DK155985A/da not_active Application Discontinuation
- 1985-04-03 DE DE19853512225 patent/DE3512225A1/de active Granted
- 1985-04-03 SE SE8501680A patent/SE466205B/sv not_active IP Right Cessation
- 1985-04-03 DD DD85274832A patent/DD236735A5/de unknown
- 1985-04-04 NL NL8501002A patent/NL192925C/nl not_active IP Right Cessation
- 1985-04-04 IE IE86685A patent/IE58408B1/en not_active IP Right Cessation
- 1985-04-04 OA OA58561A patent/OA07985A/xx unknown
- 1985-04-04 FI FI851379A patent/FI84830C/fi not_active IP Right Cessation
- 1985-04-04 CH CH1498/85A patent/CH669197A5/de not_active IP Right Cessation
- 1985-04-04 GB GB08508846A patent/GB2157293B/en not_active Expired
- 1985-04-04 AU AU40862/85A patent/AU580990B2/en not_active Expired
- 1985-04-04 PT PT80246A patent/PT80246B/pt unknown
- 1985-04-05 IL IL74826A patent/IL74826A/xx not_active IP Right Cessation
- 1985-04-05 FR FR8505281A patent/FR2563832B1/fr not_active Expired
- 1985-04-05 IT IT20267/85A patent/IT1190353B/it active
- 1985-04-05 LU LU85840A patent/LU85840A1/fr unknown
- 1985-04-05 AT AT0103985A patent/AT388735B/de not_active IP Right Cessation
- 1985-04-08 GR GR850883A patent/GR850883B/el not_active IP Right Cessation
- 1985-04-08 ES ES542013A patent/ES8607318A1/es not_active Expired
- 1985-04-08 RU SU853878102A patent/RU2056425C1/ru active
- 1985-04-09 HU HU851299A patent/HU193750B/hu unknown
- 1985-04-09 KR KR1019850002383A patent/KR870002166B1/ko not_active IP Right Cessation
- 1985-04-09 HU HU87151A patent/HU204277B/hu unknown
- 1985-04-09 BE BE0/214810A patent/BE902148A/fr not_active IP Right Cessation
- 1985-04-09 JP JP60075233A patent/JPS615084A/ja active Granted
- 1985-04-09 YU YU60085A patent/YU46151B/sh unknown
- 1985-11-12 JP JP60252139A patent/JPS61143391A/ja active Granted
- 1985-11-12 JP JP60252140A patent/JPS61143387A/ja active Granted
- 1985-11-12 JP JP60252138A patent/JPS61143390A/ja active Granted
-
1986
- 1986-01-31 ES ES551551A patent/ES8706694A1/es not_active Expired
- 1986-01-31 ES ES551550A patent/ES8706155A1/es not_active Expired
- 1986-02-06 SU SU864019975A patent/SU1487814A3/ru active
- 1986-02-06 SU SU864023036A patent/SU1367858A3/ru active
- 1986-02-06 SU SU864018257A patent/SU1375140A3/ru active
- 1986-02-06 SU SU864020682A patent/SU1436882A3/ru active
- 1986-03-03 DD DD86287525A patent/DD251752A5/de unknown
- 1986-09-10 ES ES557060A patent/ES8800949A1/es not_active Expired
-
1987
- 1987-06-25 YU YU118987A patent/YU46213B/sh unknown
- 1987-09-10 GB GB08721346A patent/GB2194789B/en not_active Expired
- 1987-09-10 GB GB08721347A patent/GB2194790B/en not_active Expired
- 1987-10-01 MY MYPI87002761A patent/MY101940A/en unknown
-
1988
- 1988-11-11 AU AU25041/88A patent/AU610278B2/en not_active Expired
-
1989
- 1989-04-04 IE IE121089A patent/IE58403B1/en not_active IP Right Cessation
- 1989-04-06 SE SE8901224A patent/SE470259B/sv not_active IP Right Cessation
- 1989-04-06 SE SE8901225A patent/SE505256C2/sv not_active IP Right Cessation
- 1989-04-06 SE SE8901226A patent/SE470260B/sv not_active IP Right Cessation
-
1991
- 1991-08-12 CA CA000616143A patent/CA1340638C/en not_active Expired - Fee Related
- 1991-08-21 CA CA000616144A patent/CA1340672C/en not_active Expired - Fee Related
Also Published As
Similar Documents
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RU2024530C1 (ru) | Соединение цефема или его фармацевтически приемлемая соль | |
JPS6388187A (ja) | 3−アンモニオプロペニルセフエム誘導体 | |
JPS62228084A (ja) | セフアロスポリン誘導体 | |
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JPS63239277A (ja) | チアゾール酢酸誘導体 | |
JPS6127991A (ja) | セフアロスポリン誘導体その製造法およびそれを有効成分とする抗菌剤 | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |