PT2263723E - Mecanismo de accionamento para dispositivo de distribuição de fármaco - Google Patents

Mecanismo de accionamento para dispositivo de distribuição de fármaco Download PDF

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Publication number
PT2263723E
PT2263723E PT101842482T PT10184248T PT2263723E PT 2263723 E PT2263723 E PT 2263723E PT 101842482 T PT101842482 T PT 101842482T PT 10184248 T PT10184248 T PT 10184248T PT 2263723 E PT2263723 E PT 2263723E
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PT
Portugal
Prior art keywords
sleeve
dose dial
pen
dose
drive sleeve
Prior art date
Application number
PT101842482T
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English (en)
Inventor
David Aubrey Plumptre
Robert Frederick Veasey
Robert Perkins
Original Assignee
Sanofi Aventis Deutschland
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9954010&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2263723(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of PT2263723E publication Critical patent/PT2263723E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
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    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
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    • A61M5/178—Syringes
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    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31563—Mechanically operated dose setting member interacting with a displaceable stop member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
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    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
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    • A61M2205/00—General characteristics of the apparatus
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    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/31—Details
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    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
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    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Coating Apparatus (AREA)
  • Transmission Devices (AREA)

Description

DESCRIÇÃO
"MECANISMO DE ACCIONAMENTO PARA DISPOSITIVO DE DISTRIBUIÇÃO DE FÁRMACO" A presente invenção refere-se a dispositivos de injecção do tipo caneta, isto é, a dispositivos de injecção do tipo que proporcionam a administração por injecção de medicamentos a partir de um cartucho multidose. Em particular, a presente invenção refere-se aos dispositivos de injecção em que um utilizador pode estabelecer a dose.
Estes dispositivos de injecção têm aplicação em pessoas sem treino médico formal que precisam de injecções requlares. Isto é cada vez mais comum entre os que sofrem de diabetes em que o auto-tratamento possibilita que essas pessoas conduzam uma gestão eficaz da sua diabetes.
Estas circunstâncias estabelecem vários requisitos para os dispositivos de injecção do tipo caneta deste tipo. 0 dispositivo de injecção deve ser de construção robusta, embora fácil de utilizar em termos de manipulação das peças e da compreensão do seu funcionamento por um utilizador. No caso de pessoas com diabetes, muitos utilizadores estarão fisicamente debilitados e a sua visão também pode ser deficiente. Quando o dispositivo de injecção for descartável em vez de reutilizável, o dispositivo de injecção deve ser de fabrico barato e fácil de eliminar (sendo, de um modo preferido, adequado para reciclagem). 1 0 documento ΕΡ 0937471 Α2 refere-se a uma caneta de distribuição de medicamento compreendendo um conjunto caneta-agulha, um dispositivo de retenção de ampola incluindo uma ampola contendo um medicamento a distribuir e possuindo a caneta-agulha fixa de um modo desmontável a uma extremidade distai. A caneta compreende ainda um corpo possuindo o dispositivo de retenção de ampola montado numa extremidade distai e incluindo um mecanismo de controlo de dose para definir uma dose desejada a distribuir a partir da ampola, um mecanismo de accionamento para distribuir a dose desejada a partir da ampola e um tubo cilíndrico para a interacção do mecanismo de controlo de dose com o mecanismo de accionamento. É uma vantagem da presente invenção proporcionar um dispositivo de injecção do tipo caneta melhorado. Isto é alcançado por um dispositivo de injecção com as caracteristicas da reivindicação 1.
De acordo com um primeiro aspecto da presente invenção, um dispositivo de injecção do tipo caneta compreende um corpo; uma haste de êmbolo adaptada para actuar através do corpo; uma manga de marcação de dose posicionada entre o corpo e a haste de êmbolo, possuindo a manga de marcação de dose uma rosca helicoidal com um primeiro passo; uma manga de accionamento posicionada entre a manga de marcação de dose e a haste de êmbolo, possuindo a manga de accionamento uma ranhura helicoidal com um segundo passo; 2 em que o primeiro passo da rosca helicoidal e o segundo passo da ranhura helicoidal são iguais; e em que a haste de êmbolo é possui uma primeira rosca e uma segunda rosca dispostas em oposição uma à outra.
De um modo preferido, a haste de êmbolo possui uma primeira parte roscada numa primeira extremidade e uma segunda parte roscada numa segunda extremidade; uma inserção ou flange estendendo-se radialmente para dentro está posicionada no corpo e através da qual a primeira parte roscada da haste de êmbolo pode rodar; sendo a manga de marcação de dose rotativa em relação ao corpo e à inserção; estando a manga de accionamento ligada de modo desmontável à manga de marcação de dose e ligada à haste de êmbolo para rotação em relação a esta ao longo da segunda parte roscada da haste de êmbolo; um botão está posicionado na manga de marcação de dose e é rotativo em relação à manga de marcação de dose; e são proporcionados meios de embraiagem que, após pressão do botão, permitem a rotação entre a manga de marcação de dose e a manga de accionamento.
De um modo preferido, o dispositivo de injecção compreende ainda uma porca que é rotativa em relação à manga de 3 accionamento e passível de ser deslocada axialmente, mas sem poder rodar, em relação ao corpo.
De um modo mais preferido, a manga de accionamento está dotada, numa primeira extremidade, com primeira e segunda flanges com uma rosca intermédia entre a primeira e segunda flanges, estando a porca disposta entre a primeira e segunda flanges e fixa ao corpo por um meio estriado. Além disso, pode ser proporcionado um primeiro batente radial numa segunda face da porca e pode ser proporcionado um segundo batente radial numa primeira face da segunda flange.
De um modo preferido, a primeira rosca da haste de êmbolo está disposta em oposição à segunda rosca da haste de êmbolo.
De um modo preferido, uma segunda extremidade da embraiagem está dotada com uma pluralidade de dentes de engate adaptados para se engatarem numa segunda extremidade da manga de marcação de dose.
De um modo preferido, o dispositivo de injecção do tipo caneta inclui ainda um meio de aviso disposto entre o meio de embraiagem e o meio estriado proporcionado no corpo.
De um modo mais preferido, o meio de aviso compreende uma manga dotada, numa primeira extremidade, com um braço estendendo-se de um modo helicoidal, uma extremidade livre do braço possuindo um elemento dentado e, numa segunda extremidade, com uma pluralidade de dentes de serra direccionados de modo circunferencial adaptados para se engatarem numa correspondente pluralidade de dentes de serra circunferenciais proporcionados no meio de embraiagem. 4
Em alternativa, o meio de aviso compreende uma manga dotada, numa primeira extremidade, com, pelo menos, um braço estendendo-se de um modo helicoidal e, pelo menos, um elemento de mola, uma extremidade livre do braço possuindo um elemento dentado e, numa segunda extremidade, com uma pluralidade de dentes de serra direccionados de modo circunferencial adaptados para se engatarem numa correspondente pluralidade de dentes de serra direccionados de modo circunferencial proporcionados no meio de embraiagem.
De um modo preferido, o corpo principal está dotado com uma pluralidade de batentes de dose máxima adaptados para serem contactados por um batente radial proporcionado na manga de marcação de dose. De um modo mais preferido, pelo menos, um dos batentes de dose máxima compreende um batente radial posicionado entre uma estria helicoidal e o meio estriado proporcionado numa segunda extremidade do corpo. Em alternativa, pelo menos, um dos batentes de dose máxima compreende uma parte de uma parte de janela elevada proporcionada numa segunda extremidade do corpo.
De um modo preferido, a manga de marcação de dose está dotada com uma pluralidade de elementos estendendo-se radialmente adaptados para contactarem uma correspondente pluralidade de batentes radiais proporcionados numa segunda extremidade do corpo. A invenção será agora descrita fazendo referência aos desenhos anexos, nos quais: - 5 A Figura 1 mostra uma vista em corte de um dispositivo de injecção do tipo caneta, de acordo com a presente invenção, numa primeira posição com cartucho cheio; A Figura 2 mostra uma vista em corte do dispositivo de injecção do tipo caneta da Figura 1 numa segunda posição de primeira dose máxima marcada; A Figura 3 mostra uma vista em corte do dispositivo de injecção do tipo caneta da Figura 1 numa terceira posição de primeira dose máxima distribuída; A Figura 4 mostra uma vista em corte do dispositivo de injecção do tipo caneta da Figura 1 numa quarta posição de dose final marcada; A Figura 5 mostra uma vista em corte do dispositivo de injecção do tipo caneta da Figura 1 numa quinta posição de dose final distribuída; A Figura 6 mostra uma vista cortada de um primeiro pormenor do dispositivo de injecção do tipo caneta da Figura 1; A Figura 7 mostra uma vista parcialmente cortada de um segundo pormenor do dispositivo de injecção do tipo caneta da Figura 1; A Figura 8 mostra uma vista parcialmente cortada de um terceiro pormenor do dispositivo de injecção do tipo caneta da Figura 1; A Figura 9 mostra o movimento relativo de partes do dispositivo de injecção do tipo caneta mostrado na Figura 1 durante a marcação de aumento de dose; 6 A Figura 10 mostra o movimento relativo de partes do dispositivo de injecção do tipo caneta mostrado na Figura 1 durante a marcação de diminuição de dose; A Figura 11 mostra o movimento relativo de partes do dispositivo de injecção do tipo caneta mostrado na Figura 1 durante a distribuição de uma dose; A Figura 12 mostra uma vista parcialmente cortada do dispositivo de injecção do tipo caneta da Figura 1 na segunda posição de primeira dose máxima marcada; A Figura 13 mostra uma vista parcialmente cortada do dispositivo de injecção do tipo caneta da Figura 1 na quarta posição de dose final marcada; A Figura 14 mostra uma vista parcialmente cortada do dispositivo de injecção do tipo caneta da Figura 1 numa das, primeira, terceira ou quinta posições; A Figura 15 mostra uma vista cortada de uma primeira parte de um corpo principal do dispositivo de injecção do tipo caneta da Figura 1; e A Figura 16 mostra uma vista cortada de uma segunda parte do corpo principal do dispositivo de injecção do tipo caneta da Figura 1.
Fazendo primeiro referência às Figuras 1 a 5, pode ver-se um dispositivo de injecção do tipo caneta de acordo com a presente invenção em várias posições. 7 0 dispositivo de injecção do tipo caneta compreende um corpo possuindo uma primeira parte 2 de retenção de cartucho e uma segunda parte 4 de corpo principal. Uma primeira extremidade do meio 2 de retenção de cartucho e uma segunda extremidade do corpo 4 principal estão fixas uma à outra por caracteristicas 6 de retenção. Na forma de realização ilustrada, o meio 2 de retenção de cartucho está fixo dentro da segunda extremidade do corpo 4 principal.
Proporciona-se um cartucho 8, a partir do qual podem ser distribuídas várias doses de medicamento, na parte 2 de retenção de cartucho. Um êmbolo 10 está retido numa primeira extremidade do cartucho 8.
Uma tampa 12 desmontável está retida de um modo separável sobre uma segunda extremidade da parte 2 de retenção de cartucho. Em utilização, a tampa 12 desmontável pode ser substituída, por um utilizador, por uma unidade de agulha adequada (não mostrada). Utiliza-se uma tampa 14 substituível para cobrir a parte 2 de retenção de cartucho que se estende a partir do corpo 4 principal. De um modo preferido, as dimensões exteriores da tampa 14 substituível são semelhantes ou idênticas às dimensões exteriores do corpo 4 principal para proporcionar a impressão de um todo unitário quando a tampa 14 substituível está na posição de cobertura da parte 2 de retenção de cartucho.
Na forma de realização ilustrada, proporciona-se uma inserção 16 numa primeira extremidade do corpo 4 principal. A inserção 16 está fixa, impedida de movimento rotacional ou longitudinal. A inserção 16 está dotada com uma abertura 18 circular roscada estendendo-se através dela. Em alternativa, a inserção pode ser formada de um modo integrante com o corpo 4 principal com a forma de uma flange dirigida radialmente para dentro possuindo uma rosca interna.
Uma primeira rosca 19 estende-se a partir de uma primeira extremidade de uma haste 20 de êmbolo. A haste 20 de êmbolo possui uma secção geralmente circular. A primeira extremidade da haste 20 de êmbolo estende-se através da abertura 18 roscada na inserção 16. Uma base 22 de pressão está posicionada na primeira extremidade da haste 20 de êmbolo. A base 22 de pressão está disposta para contactar uma segunda extremidade do êmbolo 10 de cartucho. Uma segunda rosca 24 estende-se a partir de uma segunda extremidade da haste 20 de êmbolo. Na forma de realização ilustrada, a segunda rosca 24 compreende uma série de roscas parciais em vez de uma rosca completa. A forma de realização ilustrada é mais fácil de fabricar e ajuda a reduzir a força total necessária a um utilizador para obrigar o medicamento a ser distribuído. A primeira rosca 19 e a segunda rosca 24 estão dispostas em oposição. A segunda extremidade da haste 20 de êmbolo está dotada com uma reentrância de recepção.
Uma manga 30 de accionamento estende-se em torno da haste 20 de êmbolo. A manga 30 de accionamento é geralmente cilíndrica. A manga 30 de accionamento está dotada, numa primeira extremidade, com uma primeira flange 32 estendendo-se radialmente. Uma segunda flange 34 estendendo-se radialmente é proporcionada espaçada de uma distância ao longo da manga 30 de accionamento a partir da primeira flange 32. Proporciona-se uma rosca 36 intermédia numa parte exterior da manga 30 de accionamento estendendo-se entre a primeira flange 32 e a 9 segunda flange 34. Uma ranhura 38 helicoidal estende-se ao longo da superfície interna da manga 30 de accionamento. A segunda rosca 24 da haste 20 de êmbolo está adaptada para trabalhar dentro da ranhura 38 helicoidal.
Uma primeira extremidade da primeira flange 32 está adaptada para se ajustar a um segundo lado da inserção 16.
Uma porca 40 está posicionada entre a manga 30 de accionamento e o corpo 2 principal, disposta entre a primeira flange 32 e a segunda flange 34. Na forma de realização ilustrada, a porca 40 é uma meia-porca. Isto auxilia a montagem do dispositivo de injecção. A porca 40 possui uma rosca interna que se ajusta à rosca 36 intermédia. A superfície exterior da porca 40 e uma superfície interna do corpo 4 principal estão fixas uma à outra por estrias 42 (ver Figuras 10, 11, 15 e 16) para impedir a rotação relativa entre a porca 40 e o corpo 4 principal, embora permitindo movimento longitudinal relativo entre eles.
Forma-se um rebordo 37 entre uma segunda extremidade da manga 30 de accionamento e uma extensão 38 proporcionada na segunda extremidade da manga 30 de accionamento. A extensão 38 possui diâmetros reduzidos, interior e exterior, em comparação com o resto da manga 30 de accionamento. Uma segunda extremidade da extensão 38 está dotada com uma flange 39 dirigida radialmente para fora.
Um dispositivo 50 de aviso e uma embraiagem 60 estão dispostos em torno da manga 30 de accionamento, entre a manga 30 de accionamento e uma manga 70 de marcação de dose (a descrever abaixo). 10 0 dispositivo 50 de aviso está posicionado adjacente à segunda flange 34 da manga 30 de accionamento. O dispositivo 50 de aviso é geralmente cilíndrico e está dotado, numa primeira extremidade, com um braço 52 flexível estendendo-se de um modo helicoidal (mostrado muito distintamente na Figura 6). Uma extremidade livre do braço 52 está dotada com um elemento 54 dentado dirigido radialmente. Uma segunda extremidade do dispositivo 50 de aviso está dotada com uma série de dentes 56 de serra direccionados de modo circunferencial (cf Figura 7) . Cada dente de serra compreende uma superfície dirigida longitudinalmente e uma superfície inclinada.
Numa forma de realização alternativa (não mostrada) o meio de aviso inclui ainda, pelo menos, um elemento de mola. O, pelo menos um, elemento de mola ajuda na reposição do meio 60 de embraiagem a seguir à distribuição. O meio 60 de embraiagem está posicionado adjacente à segunda extremidade da manga 3 0 de accionamento. O meio 60 de embraiagem é geralmente cilíndrico e está dotado, numa primeira extremidade, com uma série de dentes 66 de serra direccionados de modo circunf erencial (ver a Figura 7) . Cada dente de serra compreende uma superfície dirigida longitudinalmente e uma superfície inclinada. Em direcção à segunda extremidade 64 do meio 60 de embraiagem está posicionada uma flange 62 dirigida radialmente para dentro. A flange 62 do meio 60 de embraiagem está disposta entre o rebordo 37 da manga 30 de accionamento e a flange 39 dirigida radialmente para fora, da extensão 38. A segunda extremidade do meio 60 de embraiagem está dotada com uma pluralidade de dentes 65 de engate (Figura 8). A embraiagem 60 está fixa à manga 30 de accionamento por meio de estrias (não 11 mostradas) para impedir a rotação relativa entre a embraiagem 60 e a manga 30 de accionamento.
Na forma de realização ilustrada, o dispositivo 50 de aviso e a embraiagem 60 estendem-se, cada um deles, aproximadamente metade do comprimento da manga 30 de accionamento. Contudo, será compreendido gue são possíveis outras disposições referentes aos comprimentos relativos destas peças. O dispositivo 50 de aviso e o meio 60 de embraiagem estão normalmente engatados, isto é, como mostrado na figura 7.
Uma manga 70 de marcação de dose é proporcionada no exterior do dispositivo 50 de aviso e do meio 60 de embraiagem e do corpo 4 principal radialmente para dentro. Proporciona-se uma ranhura 74 helicoidal em torno de uma superfície exterior da manga 70 de marcação de dose. O corpo 4 principal está dotado com uma janela 44 através da gual se pode ver uma parte da superfície exterior da manga de marcação de dose. O corpo 4 principal está ainda dotado com uma estria 46 helicoidal, adaptada para ser encaixada na ranhura 74 helicoidal, na superfície exterior da manga 70 de marcação de dose. A estria 46 helicoidal estende-se num único varrimento da superfície interior do corpo 4 principal. Proporciona-se um primeiro batente 100 entre as estrias 42 e a estria 46 helicoidal (Figura 15). Um segundo batente 102, disposto com um ângulo de 180° relativamente ao primeiro batente 100 é formado por uma estrutura circundante da janela 44 no corpo 4 principal (Figura 16). 12
De um modo conveniente, uma indicação visual da dose que pode ser marcada, por exemplo, números de referência (não mostrados), é proporcionada na superfície exterior da manga 70 de marcação de dose. De um modo conveniente, a janela 44 apenas permite a visualização de uma indicação visual da dose marcada no momento.
Uma segunda extremidade da manga 70 de marcação de dose está dotada com uma flange dirigida para dentro com a forma de vários elementos 75 estendendo-se radialmente. Um marcador 76 de dose está disposto em torno de uma superfície exterior da segunda extremidade da manga 70 de marcação de dose. Um diâmetro exterior do marcador 76 de dose corresponde, de um modo preferido, ao diâmetro exterior do corpo 4 principal. O marcador 76 de dose está fixo à manga 70 de marcação de dose de modo a impedir movimento relativo entre eles. O marcador 76 de dose está dotado com uma abertura 78 central. Uma reentrância 80 anular posicionada na segunda extremidade do marcador 76 de dose estende-se em torno da abertura 78.
Um botão 82 de secção geralmente em "1" é proporcionado numa segunda extremidade do dispositivo de injecção do tipo caneta. Uma haste 84 do botão 82 pode estender-se através da abertura 78 no marcador 76 de dose, através do diâmetro interior da extensão 38 da manga 30 de accionamento e para dentro da reentrância 26 de recepção da haste 20 de êmbolo. A haste 84 está retida para movimento axial limitado na manga 30 de accionamento e impedida de rotação em relação a ela. Uma cabeça 85 do botão 82 é geralmente circular. Uma saia 86 depende de uma periferia da cabeça 85. A saia 86 está adaptada para ser encaixada na reentrância 80 anular do marcador 76 de dose. 13
De seguida descrever-se-á o funcionamento do dispositivo de injecção do tipo caneta de acordo com a presente invenção. Nas Figuras 9, 10 e 11, as setas A, B, C, D, E, F e G representam os respectivos movimentos do botão 82, do marcador 76 de dose, da manga 70 de marcação de dose, da manga 30 de accionamento, do meio 60 de embraiagem, do dispositivo 50 de aviso e da porca 40.
Para marcar uma dose (Figura 9), um utilizador roda o marcador 76 de dose (seta A) . Com o dispositivo 50 de aviso e o meio 60 de embraiagem engatados, a manga 30 de accionamento, o dispositivo 50 de aviso, o meio 60 de embraiagem e a manga 70 de marcação de dose rodam com o marcador 76 de dose. O dispositivo 50 de aviso e o meio 60 de embraiagem proporcionam uma informação de retorno audível e táctil da dose a ser marcada. É transmitido um momento através dos dentes 56, 66 de serra entre o dispositivo 50 de aviso e o meio 60 de embraiagem. 0 braço 52 flexível deforma-se e arrasta o elemento 54 dentado sobre as estrias 42 para produzir um estalido. De um modo preferido, as estrias 42 estão dispostas de tal modo que cada estalido corresponde a uma dose unitária. A ranhura 74 helicoidal na manga 70 de marcação de dose e a ranhura 38 helicoidal na manga 30 de accionamento possuem o mesmo passo. Isto permite que a manga 70 de marcação de dose (seta C) se estenda a partir do corpo 4 principal e da manga 30 de accionamento (seta D) para subir a haste 20 de êmbolo à mesma velocidade. No limite do percurso, um batente 104 radial na manga 70 de marcação de dose engata-se no primeiro batente 100 ou no segundo batente 102 proporcionados no corpo 4 principal para impedirem mais movimento. A rotação da haste 20 de êmbolo é 14 impedida devido às direcções opostas das roscas colocadas e conduzidas na haste 20 de êmbolo. A porca 40, fixa ao corpo 4 principal, é avançada ao longo da rosca 36 intermédia pela rotação da manga 30 de accionamento (seta D) . Quando se atinge a posição de dose final distribuída (Figuras 4, 5 e 13), um batente 106 radial, formado numa segunda superfície da porca 40, contacta um batente 108 radial numa primeira superfície da segunda flange 34 da manga 30 de accionamento, impedindo a porca 40 e a manga 30 de accionamento de continuarem a rodar.
Numa forma de realização alternativa (não mostrada), uma primeira superfície da porca 40 é dotada com um batente radial para contacto com um batente radial proporcionado numa segunda superfície da primeira flange 32. Isto ajuda a situar a porca 40 na posição de cartucho cheio durante a montagem do dispositivo de injecção do tipo caneta.
Se um utilizador marcar inadvertidamente uma quantidade maior do que a dosagem desejada, o dispositivo de injecção do tipo caneta permite que a dosagem seja corrigida sem a distribuição do medicamento do cartucho (Figura 10). O marcador 76 de dose é rodado ao contrário. Isto obriga o sistema a actuar de modo inverso. O braço 52 flexível actua agora como um roquete impedindo o dispositivo de aviso de rodar. O momento transmitido através do meio 60 de embraiagem obriga os dentes 56, 66 de serra a deslocarem-se uns sobre os outros para criarem os estalidos correspondentes à redução da dose marcada. De um modo preferido, os dentes 56, 66 de serra estão dispostos de modo que a extensão circunferencial de cada dente de serra corresponde a uma dose unitária. 15
Quando marcou a dose desejada, o utilizador pode, depois, distribuir esta dose premindo o botão 82 (Figura 11). Isto desloca o meio 60 de embraiagem axialmente em relação à manga 70 de marcação de dose obrigando os dentes 65 de engate a desengatarem-se. Contudo o meio 60 de embraiagem permanece fixo, em rotação, à manga 30 de accionamento. A manga 70 de marcação de dose e o marcador 76 de dose associado estão agora livres para rodar, (orientados pela estria 46 helicoidal posicionada na ranhura 74 helicoidal). O movimento axial deforma o braço 52 flexível do dispositivo 50 de aviso para assegurar que os dentes 56, 66 de serra não possam ser passados durante a distribuição. Isto impede a manga 30 de accionamento de rodar em relação ao corpo 4 principal embora seja ainda livre para se deslocar axialmente em relação a ele. Esta deformação é, subsequentemente, utilizada para impelir o dispositivo 50 de aviso e a embraiagem 60, de novo ao longo da manga 30 de accionamento para restabelecer a ligação entre a embraiagem 60 e a manga 70 de marcação de dose quando se remove a pressão do botão 82. O movimento axial longitudinal da manga 30 de accionamento obriga a haste 20 de êmbolo a rodar através da abertura 18 na inserção 16, para, desse modo, avançar o êmbolo 10 no cartucho 8. Uma vez que a dose marcada tenha sido distribuída, a manga 70 de marcação de dose fica impedida de mais rotação pelo contacto de uma pluralidade de elementos 110 (Figura 14), que se estendem a partir do marcador 76 de dose, com uma correspondente pluralidade de batentes 112 formados no corpo 4 principal (Figuras 15 e 16). Na forma de realização ilustrada, os elementos 110 estendem-se axialmente a partir do marcador 76 de 16
dose e possuem uma superfície de extremidade inclinada. A dos um posição de dose zero é determinada pelo contacto de um bordos estendendo-se axialmente, dos elementos 110, com correspondente batente 112.
Lisboa, 17 de Junho de 2013 17

Claims (4)

  1. REIVINDICAÇÕES 1. Dispositivo de injecção do tipo caneta compreendendo um corpo (4); uma haste (20) de êmbolo adaptada para actuar através do corpo; uma manga (70) de marcação de dose posicionada entre o corpo e a haste de êmbolo, a manga de marcação de dose possuindo uma rosca (74) helicoidal com um primeiro passo; uma manga (30) de accionamento posicionada entre a manga de marcação de dose e a haste de êmbolo, a manga de accionamento possuindo uma ranhura (38) helicoidal com um segundo passo; em que o primeiro passo da rosca (74) helicoidal e o segundo passo da ranhura (38) helicoidal são iguais; caracterizado por a haste de êmbolo possuir uma primeira rosca (19) e uma segunda rosca (24) que estão dispostas em oposição uma à outra.
  2. 2. Dispositivo de injecção do tipo caneta de acordo com a reivindicação 1, em que a haste (20) de êmbolo possui uma secção geralmente circular.
  3. 3. Dispositivo de injecção do tipo caneta de acordo com as reivindicações 1 ou 2, em que a segunda parte (24) roscada 1 da haste (20) de êmbolo compreende uma série de roscas parciais.
  4. 4. Dispositivo qualquer : extremidade reentrância de acordo com que a segunda dotada com uma de injecção do tipo caneta sivindicação anterior, em da haste (20) de êmbolo está (26) de recepção. Lisboa, 17 de Junho de 2013 2
PT101842482T 2003-03-03 2004-03-03 Mecanismo de accionamento para dispositivo de distribuição de fármaco PT2263723E (pt)

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PT101844009T PT2266648E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
PT04716568T PT1603610E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
PT04716584T PT1603611E (pt) 2003-03-03 2004-03-03 Mecanismo de accionamento para dispositivo de distribuição de fármaco
PT101840858T PT2263721E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
PT101843472T PT2281592E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
PT101842482T PT2263723E (pt) 2003-03-03 2004-03-03 Mecanismo de accionamento para dispositivo de distribuição de fármaco
PT08012347T PT1974761E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
PT08002101T PT1920794E (pt) 2003-03-03 2004-03-03 Mecanismo de accionamento para dispositivo de distribuição de fármacos
PT101841633T PT2263722E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
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PT04716584T PT1603611E (pt) 2003-03-03 2004-03-03 Mecanismo de accionamento para dispositivo de distribuição de fármaco
PT101840858T PT2263721E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
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PT101841633T PT2263722E (pt) 2003-03-03 2004-03-03 Dispositivo de injecção do tipo caneta com manga de marcação de dose
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Families Citing this family (433)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153711T3 (es) 1998-01-30 2001-03-01 Novo Nordisk As Jeringuilla de inyeccion.
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
US9205197B2 (en) 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0308267D0 (en) 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
SI1656170T1 (sl) 2003-08-12 2019-05-31 Eli Lilly And Company Oprema za izdajanje zdravil s trojnim vijačnim navojem za mehanski pospešek
ATE526052T1 (de) 2004-03-30 2011-10-15 Lilly Co Eli Medikationsabgabegerät mit getriebeset mit einer öffnung zur aufnahme eines antriebselements
JP4874233B2 (ja) 2004-03-30 2012-02-15 イーライ リリー アンド カンパニー 最終用量の投与によって可能になるバネ駆動固定の特徴を持つ薬剤投与器具
NZ554384A (en) 2004-10-04 2010-04-30 Sanofi Aventis Deutschland Drive mechanism for drug delivery device
EP1645301A1 (en) * 2004-10-11 2006-04-12 Novo Nordisk A/S Injection device
US7686786B2 (en) 2004-10-21 2010-03-30 Novo Nordiks A/S Dial-down mechanism for wind-up pen
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7749194B2 (en) 2005-02-01 2010-07-06 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
CA2791286C (en) 2004-11-22 2015-09-01 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
DE602005026595D1 (de) 2004-12-01 2011-04-07 Novo Nordisk As Injektionsvorrichtung
DE102004063645A1 (de) * 2004-12-31 2006-07-20 Tecpharma Licensing Ag Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel
DE102005001159A1 (de) * 2005-01-10 2006-07-20 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung mit Übersetzung
WO2006077466A2 (en) * 2005-01-18 2006-07-27 Wockhardt Americas Inc Pen shaped medication injection devices
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
JP4970286B2 (ja) 2005-02-11 2012-07-04 ノボ・ノルデイスク・エー／エス 注入器具
EP1861141B1 (en) * 2005-02-17 2013-12-18 Novo Nordisk A/S A dose setting element for an injection device and having a dose setting limiting mechanism
DE102005063311A1 (de) † 2005-02-23 2006-08-24 Tecpharma Licensing Ag Verabreichungsvorrichtung mit Anzeigetrommel
EP1855744A1 (en) * 2005-02-28 2007-11-21 Novo Nordisk A/S A dose setting mechanism for an injection device
CN101163514B (zh) * 2005-04-24 2012-01-25 诺和诺德公司 注射装置
US20080221530A1 (en) * 2005-04-24 2008-09-11 Novo Nordisk A/S Injection Device With A GearBox
DE102005023824A1 (de) 2005-05-24 2006-12-07 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung
DE102005023854B4 (de) † 2005-05-24 2020-12-17 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung
EP1907031A2 (en) 2005-05-31 2008-04-09 Novo Nordisk A/S Injection device with visual end-of-content indication
WO2007006662A1 (en) * 2005-07-08 2007-01-18 Novo Nordisk A/S Injection device
ATE499962T1 (de) * 2005-07-27 2011-03-15 Novo Nordisk As Dosismechanismus für ein injektionsgerät zur begrenzung einer dosiseinstellung entsprechend der verbleibenden arzneimenge
JP4937258B2 (ja) * 2005-07-27 2012-05-23 ノボ・ノルデイスク・エー／エス 投与量制限機構及び付加的安全機構を備えた注射装置
US7650181B2 (en) 2005-09-14 2010-01-19 Zoll Medical Corporation Synchronization of repetitive therapeutic interventions
GB0524604D0 (en) * 2005-12-02 2006-01-11 Owen Mumford Ltd Injection method and apparatus
DE102005060928A1 (de) * 2005-12-20 2007-06-28 Tecpharma Licensing Ag Injektionsvorrichtung mit axial überlappendem Dosier- oder Anzeigeglied
US7780635B2 (en) * 2006-02-09 2010-08-24 Aderans Research Institute, Inc. Apparatus and methods for delivering fluid and material to a subject
WO2007104636A1 (en) 2006-03-10 2007-09-20 Novo Nordisk A/S An injection device and a method of changing a cartridge in the device
WO2007104697A2 (en) 2006-03-10 2007-09-20 Novo Nordisk A/S An injection device having a gearing arrangement
US8226618B2 (en) 2006-05-16 2012-07-24 Novo Nordisk A/S Gearing mechanism for an injection device
RU2433840C2 (ru) 2006-05-18 2011-11-20 Ново Нордиск А/С Инъецирующее устройство со средством блокирования функции
DK3626289T3 (da) 2006-09-15 2021-03-01 Ypsomed Ag Injektionsindretning med forbedret transportelement
EP1923084A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
EP1923085A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
CN101605569B (zh) 2007-02-05 2012-09-05 诺沃-诺迪斯克有限公司 注射按钮
CN101641126B (zh) 2007-03-23 2014-06-04 诺沃-诺迪斯克有限公司 包括锁定螺母的注射装置
DE102007018696A1 (de) 2007-04-18 2008-10-23 Sanofi-Aventis Deutschland Gmbh Injektionsvorrichtung zur Abgabe eines Medikaments
DE102007019124A1 (de) 2007-04-23 2008-11-06 Tecpharma Licensing Ag Rückdrehbare Dosiervorrichtung für eine Injektionsvorrichtung
DE102007026083A1 (de) * 2007-05-25 2008-11-27 Haselmeier S.A.R.L. Injektionsgerät
US8221358B2 (en) * 2007-11-20 2012-07-17 Warsaw Orthopedic, Inc. Devices and methods for delivering drug depots to a site beneath the skin
EP2234661B1 (en) 2007-12-20 2013-04-17 Novo Nordisk A/S Injection device for delivering a fixed dose of liquid drug
US8267900B2 (en) 2008-05-02 2012-09-18 Sanofi-Aventis Deutschland Gmbh Medication delivery device
JP5478606B2 (ja) 2008-05-02 2014-04-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬剤送達デバイス
MY148822A (en) * 2008-05-02 2013-06-14 Sanofi Aventis Deutschland Medication delivery device
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
WO2009150028A1 (en) * 2008-05-26 2009-12-17 Novo Nordisk A/S Improved injection device
ES2398034T3 (es) 2008-07-09 2013-03-13 Sanofi-Aventis Deutschland Gmbh Dispositivo de entrega de medicación y un método de ensamblar un dispositivo de entrega de medicación
MY152436A (en) 2008-10-13 2014-09-30 Sanofi Aventis Deutschland Drug delivery device and method of manufacturing a drug delivery device
EP3228320B1 (de) 2008-10-17 2019-12-18 Sanofi-Aventis Deutschland GmbH Kombination von einem insulin und einem glp-1-agonisten
US20100106132A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising superior and inferior covers
US9352137B2 (en) * 2008-10-29 2016-05-31 Warsaw Orthopedic, Inc. Drug cartridge for delivering a drug depot comprising a bulking agent and/or cover
US20100106136A1 (en) * 2008-10-29 2010-04-29 Warsaw Orthopedic, Inc. Drug delivery device with sliding cartridge
US9545483B2 (en) * 2008-12-02 2017-01-17 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device and medication delivery device
EP2196233A1 (en) 2008-12-12 2010-06-16 Sanofi-Aventis Deutschland GmbH Resettable drive mechanism for a medication delivery device and medication delivery device
US8840591B2 (en) 2008-12-12 2014-09-23 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a medication delivery device and medication delivery device
EP2201972A1 (en) 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Fixed dose injection device with resettable drive mechanism
EP2208503A1 (en) * 2009-01-20 2010-07-21 Sanofi-Aventis Deutschland GmbH Drive assembly and medication delivery device
CN102369033A (zh) 2009-03-30 2012-03-07 赛诺菲-安万特德国有限公司 具有改进的柱塞杆的药物输送装置
EP2414012B1 (en) 2009-03-31 2015-01-28 Sanofi-Aventis Deutschland GmbH Pen cap
WO2010115820A1 (en) 2009-03-31 2010-10-14 Sanofi-Aventis Deutschland Gmbh Method for manufacturing a drug delivery device body using an adhesive and drug delivery device body
EP2413995B1 (en) 2009-03-31 2022-09-21 Sanofi-Aventis Deutschland GmbH Dose button for a drug delivery device and method for manufacturing a dose button
DK3607982T3 (da) 2009-03-31 2023-07-17 Sanofi Aventis Deutschland Monteringsindretning og koblingsenhed til en lægemiddeladministrationsanorning
BRPI1012737A2 (pt) * 2009-03-31 2016-05-03 Sanofi Aventis Deutschland dispositivo médico tendo um mecanismo com uma mola e uso de uma mola ondulada ou arruela ondulada dentro de um dispositivo médico
CA2756578A1 (en) * 2009-03-31 2010-10-14 Sanofi-Aventis Deutschland Gmbh Drug delivery device
DE202010018285U1 (de) * 2009-03-31 2015-08-18 Sanofi-Aventis Deutschland Gmbh Medikamentenabgabevorrichtung
SG175102A1 (en) 2009-04-30 2011-12-29 Sanofi Aventis Deutschland Axially adjustable connection of piston rod to piston for drive mechanism of a drug delivery device
AU2014218406B2 (en) * 2009-06-01 2016-06-30 Sanofi-Aventis Deutschland Gmbh A resettable dose setting mechanism for a drug delivery device
US8585656B2 (en) 2009-06-01 2013-11-19 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US9108007B2 (en) 2009-06-01 2015-08-18 Sanofi-Aventis Deutschland Gmbh Spindle and bearing combination and drug delivery device
US9623187B2 (en) 2009-06-01 2017-04-18 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US9463283B2 (en) 2009-06-01 2016-10-11 Sanofi-Aventis Deutschland Gmbh Dosing mechanism for a drug deliver device
US9199040B2 (en) 2009-06-01 2015-12-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device last dose lock-out mechanism
US9457150B2 (en) 2009-06-01 2016-10-04 Sanofi-Aventis Deutschland Gmbh Biasing mechanism for a drug delivery device
US8257319B2 (en) 2009-06-01 2012-09-04 Sanofi-Aventis Deutschland Gmbh Drug delivery device inner housing having helical spline
US9125994B2 (en) 2009-06-01 2015-09-08 Sanofi—Aventis Deutschland GmbH Drug delivery device with dose dial sleeve rotational stop
US8974423B2 (en) 2009-06-01 2015-03-10 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US10034982B2 (en) * 2009-06-01 2018-07-31 Sanofi-Aventis Deutschland Gmbh Spindle for a drug delivery device
US9238106B2 (en) 2009-06-01 2016-01-19 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US8672896B2 (en) 2009-06-01 2014-03-18 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
US9950116B2 (en) 2009-06-01 2018-04-24 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US9345840B2 (en) 2009-06-01 2016-05-24 Sanofi-Aventis Deutschland Gmbh Drug delivery dose setting mechanism with variable maximum dose
US8728043B2 (en) 2009-06-01 2014-05-20 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device
TWI530306B (zh) 2009-06-02 2016-04-21 賽諾菲阿凡提斯德意志有限公司 藥物傳送裝置總成及藥物傳送裝置
PL2445551T3 (pl) 2009-06-23 2020-05-18 Tecpharma Licensing Ag Urządzenie wstrzykujące wyposażone w mechanizm dozujący, z funkcją ograniczenia wielkości ustawianej dawki produktu
EP2266647A1 (en) * 2009-06-25 2010-12-29 Sanofi-Aventis Deutschland GmbH Drive mechanism for drug delivery device
WO2011003762A1 (en) * 2009-06-30 2011-01-13 Sanofi-Aventis Deutschland Gmbh Drive mechanism and drug delivery device
WO2011026931A1 (en) 2009-09-07 2011-03-10 Sanofi-Aventis Deutschland Gmbh Drive mechanism for drug delivery device
EP2292286A1 (en) * 2009-09-07 2011-03-09 Sanofi-Aventis Deutschland GmbH Drive mechanism for a medication delivery device and medication delivery device
US9402960B2 (en) * 2009-09-30 2016-08-02 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device and use of a reset member for a drive mechanism
WO2011039210A1 (en) * 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device
DK2482899T3 (da) * 2009-09-30 2014-01-06 Sanofi Aventis Deutschland Konstruktion til indretning til indgivelse af lægemiddel
WO2011039236A1 (en) * 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Resettable drive assembly and drug delivery device
DK2482884T3 (en) * 2009-09-30 2016-02-08 Sanofi Aventis Deutschland PHARMACEUTICAL FEED DEVICE AND drive section TO A drug delivery device
WO2011039233A1 (en) 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Injection device
BR112012007338A2 (pt) 2009-09-30 2016-10-04 Sanofi Aventis Deutschland mecanismo acionador restaurável para um dispositivo de aplicação de fármaco
TW201127435A (en) * 2009-09-30 2011-08-16 Sanofi Aventis Deutschland Drive mechanism for a drug delivery device
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
US9108003B2 (en) 2009-10-16 2015-08-18 Sanofi-Aventis Deutschland Gmbh Drug delivery device
DK3170526T3 (da) 2009-10-30 2021-10-11 Sanofi Aventis Deutschland Patron til lægemiddeladministrationsanordning
US9737666B2 (en) * 2009-11-03 2017-08-22 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device and drug delivery device
UY33025A (es) 2009-11-13 2011-06-30 Sanofi Aventis Deustschland Gmbh Composicion farmaceutica que comprende un agonista de glp-1 metionina
AR080669A1 (es) 2009-11-13 2012-05-02 Sanofi Aventis Deutschland Composicion farmaceutica que comprende un agonista de glp-1, una insulina y metionina
WO2011060786A1 (en) * 2009-11-20 2011-05-26 Moeller Claus Schmidt Spring actuated dose delivery device
ES2749395T3 (es) 2009-11-20 2020-03-20 Becton Dickinson Co Dispositivo de inyección sin necesidad de un engranaje
EP2512563B1 (en) 2009-12-18 2016-11-23 Sanofi-Aventis Deutschland GmbH Dose setting mechanism with maximum dose limiting element
US8939438B2 (en) 2010-01-08 2015-01-27 Lee Spring Company Llc Plastic spring and method and apparatus for making the same
WO2011101379A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto-injector
DK2536458T3 (da) * 2010-02-18 2018-01-29 Sanofi Aventis Deutschland Koblingsmekanisme
EP2566539A1 (en) 2010-05-04 2013-03-13 Sanofi-Aventis Deutschland GmbH Drive mechanism with a low friction coating for a drug delivery device
AU2011202239C1 (en) * 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
ES2649399T3 (es) 2010-06-11 2018-01-11 Sanofi-Aventis Deutschland Gmbh Conjunto de accionamiento, componente de accionamiento y dispositivo de administración de medicamentos
CA2743207C (en) * 2010-06-18 2023-06-06 Becton, Dickinson And Company Adjustable plunger dose stop
EP2399635A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
WO2012000875A1 (en) * 2010-06-28 2012-01-05 Sanofi-Aventis Deutschland Gmbh Auto-injector
WO2012017035A1 (en) 2010-08-06 2012-02-09 Sanofi-Aventis Deutschland Gmbh Cartridge holder and method for assembling a cartridge unit for a drug delivery device
MX339614B (es) 2010-08-30 2016-06-02 Sanofi - Aventis Deutschland GmbH Uso de ave0010 para la fabricacion de un medicamento para el tratamiento de la diabetes mellitus tipo 2.
JP5903102B2 (ja) 2010-09-24 2016-04-13 イーライ リリー アンド カンパニー 用量送達装置
EP2438940A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
BR112013008872A2 (pt) 2010-10-13 2017-07-11 Sanofi Aventis Deutschland mecanismo de ajuste de dose e método de uso do mesmo
CN103153372B (zh) 2010-10-13 2015-11-25 赛诺菲-安万特德国有限公司 设定剂量的剂量设定机构和方法
JP5897016B2 (ja) * 2010-10-13 2016-03-30 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 用量設定機構及びそれを使用する方法
TWI562798B (en) * 2010-10-13 2016-12-21 Sanofi Aventis Deutschland Dose setting mechanism and method of setting a dose
DK2627375T3 (en) * 2010-10-13 2016-01-04 Sanofi Aventis Deutschland Dose adjustment mechanism and method for setting a dose
AU2011315628B2 (en) 2010-10-13 2015-05-07 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism
AR083380A1 (es) 2010-10-13 2013-02-21 Sanofi Aventis Deutschland Mecanismo de establecimiento de dosis y metodo para utilizar el mismo
EP2468330A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
USRE48593E1 (en) 2010-12-21 2021-06-15 Sanofi-Aventis Deutschland Gmbh Auto-injector
WO2012084720A1 (en) 2010-12-21 2012-06-28 Sanofi-Aventis Deutschland Gmbh Injection device with dose setting mechanism having maximum dose stop
EP2468333A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9173999B2 (en) 2011-01-26 2015-11-03 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
WO2012107493A1 (en) 2011-02-09 2012-08-16 Sanofi-Aventis Deutschland Gmbh Dual drug pen-injection device with micro-reservoirs carrying secondary drug for emergency injection
US11577029B2 (en) 2012-03-15 2023-02-14 Becton, Dickinson And Company Multiple use disposable injection pen
CA3207394A1 (en) 2011-03-16 2012-09-20 Becton, Dickinson And Company Multiple use disposable injection pen
DK2689359T3 (da) 2011-03-24 2021-02-08 Sanofi Aventis Deutschland Apparat og fremgangsmåde til påvisning af en aktiveringshandling, der kan udføres med en medicinsk anordning
TWI538707B (zh) 2011-05-06 2016-06-21 賽諾菲阿凡提斯德意志有限公司 藥物傳送裝置及用於藥物傳送裝置的匣支架
US9283325B2 (en) * 2011-05-12 2016-03-15 Shl Group Ab Medicament delivery device with dose re-setting
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
AR086930A1 (es) * 2011-06-17 2014-01-29 Sanofi Aventis Deutschland Conjunto de soporte de cartucho para dispositivos de administracion de farmacos
EP2729202B1 (en) 2011-07-07 2018-05-16 Novo Nordisk A/S Drug delivery injection pen with add-on dose capturing and display module
RU2650616C2 (ru) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Фармацевтическая комбинация для применения при гликемическом контроле у пациентов с сахарным диабетом 2 типа
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
EP3400981B1 (en) 2011-09-08 2019-12-25 Sanofi-Aventis Deutschland GmbH Method and monitoring device for monitoring operaton of a drug delivery device
JP6251172B2 (ja) * 2011-09-29 2017-12-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイスおよび薬物送達デバイスに対する方法
US20130085452A1 (en) * 2011-09-30 2013-04-04 Becton Dickinson France, S.A.S. Syringe Assembly Having a Rotatably Advanceable Plunger Rod
KR20130058350A (ko) * 2011-11-25 2013-06-04 삼성전자주식회사 자동차 램프용 발광소자 모듈
EP2606924A1 (en) 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector having a retracting syringe carrier
US9533106B2 (en) 2011-12-29 2017-01-03 Novo Nordisk A/S Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
JP6310862B2 (ja) 2012-02-13 2018-04-11 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ペン型薬物注射デバイスならびに用量の設定および投与を監視しロギングする（ｌｏｇｇｉｎｇ）ための電子アドオン（ａｄｄ−ｏｎ）監視モジュール
WO2013127876A1 (de) 2012-02-29 2013-09-06 Tecpharma Licensing Ag Injektionsvorrichtung mit verbessertem kolbenstangenantrieb
PL2825227T3 (pl) 2012-03-15 2019-10-31 Becton Dickinson Co Jednorazowy pen do inekcji wielokrotnego użytku
US9033912B2 (en) 2012-03-28 2015-05-19 Warsaw Orthopedic, Inc. Drug delivery system
WO2013149769A1 (de) 2012-04-05 2013-10-10 Tecpharma Licensing Ag Injektionsvorrichtung mit verbessertem kolbenstangenantrieb
EP2833946B1 (en) 2012-04-05 2017-10-04 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug injection device comprising adhesive to block drive at end of device life to prevent reuse
AU2013245106B2 (en) 2012-04-05 2017-07-27 Sanofi-Aventis Deutschland Gmbh Pen -type injector with window element
PL2836259T3 (pl) 2012-04-11 2016-11-30 Uchwyt wkładu i iniektor typu pen
US10065000B2 (en) 2012-04-19 2018-09-04 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device and drug delivery device
CH706567A2 (de) * 2012-05-16 2013-11-29 Tecpharma Licensing Ag Verbesserte Vorrichtung zum Einstellen einer Dosis mit einem Begrenzungsmechanismus für ein Gerät zur Verabreichung eines Produkts.
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
WO2013178600A1 (en) 2012-05-30 2013-12-05 Sanofi-Aventis Deutschland Gmbh Bearing for a piston rod body for a drug delivery device, a piston rod arrangement and a piston rod body
WO2014023771A1 (en) 2012-08-08 2014-02-13 Sanofi-Aventis Deutschland Gmbh Drug delivery device with tamper-evident closure
WO2014029724A1 (en) 2012-08-20 2014-02-27 Sanofi-Aventis Deutschland Gmbh Drug delivery device and method for detecting contact between piston rod and cartridge bung via vibration excitation and monitoring
JP6301334B2 (ja) 2012-08-20 2018-03-28 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイスおよび接触を検出する方法
CN104540535A (zh) 2012-08-20 2015-04-22 赛诺菲-安万特德国有限公司 电检测活塞杆与药筒筒塞之间的接触的方法和药物输送装置
JP6314139B2 (ja) 2012-08-31 2018-04-18 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス
JP6314140B2 (ja) 2012-08-31 2018-04-18 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス
US10780231B2 (en) 2012-09-11 2020-09-22 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device and drug delivery device
CA2808738C (en) * 2012-09-26 2014-03-18 Gadlight, Inc Portable medicine injection device and metering system
US9950126B2 (en) 2012-12-10 2018-04-24 Merck Sharp & Dohme Corp. Medication injector with near-empty alert
TWI653069B (zh) 2013-03-11 2019-03-11 德商賽諾菲阿凡提斯德意志有限公司 活塞桿以及包含活塞桿的藥物輸送裝置
US10406293B2 (en) 2013-03-13 2019-09-10 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device comprising a feedback feature
CN105228677B (zh) 2013-03-13 2020-02-11 赛诺菲-安万特德国有限公司 用于药物输送装置的包括反馈特征部的组件
CN110354255B (zh) 2013-04-03 2024-05-14 赛诺菲 通过长效胰岛素制剂治疗糖尿病
JP6310057B2 (ja) 2013-04-10 2018-04-11 サノフイ 投薬速度制御機構および注射デバイス
RU2671419C2 (ru) 2013-04-10 2018-10-31 Санофи Инъекционное устройство
RU2015147856A (ru) * 2013-04-10 2017-05-15 Санофи Механизм управления скоростью подачи и инъекционное устройство
CN105102030A (zh) 2013-04-10 2015-11-25 赛诺菲 注射装置
AR095801A1 (es) 2013-04-10 2015-11-11 Sanofi Sa Dispositivo de inyección
EP2983755B1 (en) 2013-04-10 2020-02-12 Sanofi Injection device
DK2983735T3 (da) 2013-04-10 2021-03-01 Sanofi Sa Drivmekanisme til en lægemiddeladministrationsanordning
RU2015147855A (ru) 2013-04-10 2017-05-23 Санофи Инъекционное устройство
WO2014166888A1 (en) * 2013-04-10 2014-10-16 Sanofi Injection device
WO2014166917A1 (en) 2013-04-10 2014-10-16 Sanofi Injection device
JP6379180B2 (ja) * 2013-04-10 2018-08-22 サノフイ 薬物送達デバイスの駆動機構
EP2983739B1 (en) * 2013-04-10 2020-04-01 Sanofi Drive mechanism of a drug delivery device
JP6546155B2 (ja) 2013-04-10 2019-07-17 サノフイＳａｎｏｆｉ 注射デバイスおよび組立て方法
EP2983743B1 (en) * 2013-04-10 2019-05-22 Sanofi Drive mechanism for a drug delivery device
WO2014166897A1 (en) * 2013-04-10 2014-10-16 Sanofi Drive mechanism of a drug delivery device
CN105102028B (zh) 2013-04-10 2019-02-01 赛诺菲 用于药物输送装置的驱动组件
AR095803A1 (es) 2013-04-10 2015-11-11 Sanofi Sa Dispositivo de inyección
MX2015014297A (es) 2013-04-10 2015-12-08 Sanofi Sa Dispositivo de inyeccion.
JP6395808B2 (ja) 2013-04-10 2018-09-26 サノフイＳａｎｏｆｉ 注射デバイス
TW201509469A (zh) 2013-04-10 2015-03-16 Sanofi Sa 注射裝置（六）
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
DK2996744T3 (en) 2013-05-16 2019-02-11 Sanofi Aventis Deutschland MECHANISM OF A PHARMACEUTICAL SUPPLY DEVICE
US10543320B2 (en) 2013-05-27 2020-01-28 Sanofi-Aventis Deutschland Gmbh Drive assembly for a drug delivery and drug delivery device
EP2823841A1 (en) 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
USRE46814E1 (en) 2013-07-16 2018-05-01 Sanofi-Aventis Deutschland Gmbh Medication delivery device
JP2016526995A (ja) 2013-07-17 2016-09-08 サノフイ 薬物送達デバイス
US10512731B2 (en) 2013-07-17 2019-12-24 Sanofi Drug delivery device
CN105377341B (zh) 2013-07-17 2020-08-04 赛诺菲 药物输送装置
JP6609248B2 (ja) * 2013-07-17 2019-11-20 サノフイ 薬物送達デバイス
WO2015007823A1 (en) 2013-07-17 2015-01-22 Sanofi Drug delivery device
DK3021902T3 (en) 2013-07-17 2018-12-17 Sanofi Sa MEDICATION DELIVERY DEVICE
MX2016001245A (es) 2013-08-02 2016-05-24 Becton Dickinson Co Pluma de inyeccion.
CN105492050B (zh) 2013-08-29 2019-06-21 赛诺菲-安万特德国有限公司 用于药物输送装置的盖
AU2014314290B2 (en) * 2013-08-29 2018-11-08 Sanofi-Aventis Deutschland Gmbh Housing and cap for an injection device made of an outer metal part and an inner plastic part
JP6595997B2 (ja) * 2013-09-03 2019-10-23 サノフイ 薬物送達デバイス用の駆動機構
WO2015032783A1 (en) 2013-09-03 2015-03-12 Sanofi Drive mechanism and injection device herewith
JP6457529B2 (ja) 2013-09-03 2019-01-23 サノフイＳａｎｏｆｉ 駆動機構および駆動機構を有する注射デバイス
US10220153B2 (en) 2013-09-03 2019-03-05 Sanofi Pen type drug injection device with dose limiting nut to prevent setting of a dose higher than the amount of drug remaining
EP2851821A1 (en) 2013-09-20 2015-03-25 Sanofi-Aventis Deutschland GmbH Medical device and method operating same
US9901684B2 (en) 2013-10-17 2018-02-27 Warsaw Orthopedic, Inc. Drug delivery device with retaining member
EP3068470B1 (en) 2013-11-15 2020-12-23 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device and drug delivery device
US10195360B2 (en) 2013-11-15 2019-02-05 Sanofi-Aventis Deutschland Gmbh Member and assembly for a drug delivery device, drug delivery device and use of a member
JP6592432B2 (ja) 2013-11-15 2019-10-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイスのアセンブリおよび薬物送達デバイス
CN105764554B (zh) * 2013-11-22 2019-07-05 赛诺菲-安万特德国有限公司 具有单向联接部的药物输送装置
EP3071261B1 (en) 2013-11-22 2019-05-08 Sanofi-Aventis Deutschland GmbH Drug delivery device
JP6711749B2 (ja) * 2013-11-22 2020-06-17 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 用量ノブクラッチ（ｄｏｓｅ ｋｎｏｂ ｃｌｕｔｃｈ）を有する薬物送達デバイス
US11241544B2 (en) 2013-12-05 2022-02-08 Novo Nordisk A/S Housing for a medical injection device
AR098642A1 (es) 2013-12-09 2016-06-01 Sanofi Aventis Deutschland Elemento accionador y mecanismo para un dispositivo de suministro de fármaco y dispositivo de suministro de fármaco
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
EP2923714A1 (en) 2014-03-28 2015-09-30 Sanofi-Aventis Deutschland GmbH Autoinjector triggered by skin contact
EP3125973B1 (en) 2014-03-31 2018-03-14 Sanofi-Aventis Deutschland GmbH Pen-type drug injection device with particular dose scale and dose display window comprising optical filter for unambiguous display of set dose value
JP6703492B2 (ja) 2014-05-28 2020-06-03 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス用の用量標示機構および薬物送達デバイス
CN105214203B (zh) * 2014-06-13 2018-09-18 中国人民解放军第二军医大学 一种便携式骨内输液器
USD770038S1 (en) 2014-06-26 2016-10-25 Eli Lilly And Company Medication injection device
CN105288790B (zh) * 2014-06-26 2018-07-03 群康生技股份有限公司 注射器
TW201603851A (zh) 2014-07-01 2016-02-01 賽諾菲公司 藥物輸送裝置
TW201603852A (zh) 2014-07-01 2016-02-01 賽諾菲公司 彈簧裝置及具有該彈簧裝置之藥物傳輸裝置
USD809652S1 (en) 2014-07-25 2018-02-06 Warsaw Orthopedic, Inc. Drug delivery device
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
JP2017521191A (ja) * 2014-07-25 2017-08-03 ノボ・ノルデイスク・エー／エス 医療装置用のナットアセンブリ
US10080877B2 (en) 2014-07-25 2018-09-25 Warsaw Orthopedic, Inc. Drug delivery device and methods having a drug cartridge
EP3006068B1 (en) * 2014-10-09 2020-12-09 Ypsomed AG Medication dispensing apparatus with sub dose prevention
AR102191A1 (es) * 2014-10-09 2017-02-08 Sanofi Sa Método para ensamblar un resorte impulsor y dispositivo de administración de fármacos con un resorte
AR102189A1 (es) 2014-10-09 2017-02-08 Sanofi Sa Alojamiento y dispositivo de administración de fármacos con el mismo y método para producir un alojamiento
US10603435B2 (en) 2014-12-08 2020-03-31 Sanofi Drive mechanism for use in a drug delivery device
US10576212B2 (en) 2014-12-08 2020-03-03 Sanofi Dose setting mechanism and drug delivery device herewith
CN107027294A (zh) 2014-12-08 2017-08-08 赛诺菲 咔嗒发声器组合体和具有该咔嗒发声器组合体的药物输送装置
EP3229865B1 (en) 2014-12-08 2020-06-03 Sanofi Drive mechanism and drug delivery device herewith
CN106999661A (zh) 2014-12-08 2017-08-01 赛诺菲 包括棱镜的药物输送装置
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
KR101976299B1 (ko) 2014-12-12 2019-05-07 에스에이치엘 메디컬 아게 투여량 설정 기구 및 투여량 설정 기구를 포함하는 약물 송달 장치
US9474864B2 (en) 2014-12-15 2016-10-25 Brell Medical Innovations, LLC Safety syringe and methods for administration of a medicament dose by subject weight
EP3045193A1 (en) 2015-01-19 2016-07-20 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device
EP3058974A1 (en) 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Injection device with supplementary device
EP3058970A1 (en) 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Data collection device for attachment to an injection device
EP3132821B1 (en) 2015-03-03 2018-12-19 Innovative Precision Instruments Limited Drug information detection apparatus and drug information detection type injection apparatus
JP6901398B2 (ja) 2015-03-06 2021-07-14 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 注射デバイスのセンサ装置
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
EP3274025B1 (en) 2015-03-23 2020-05-27 Sanofi-Aventis Deutschland GmbH Cartridge holder of an injection device
RU2714666C2 (ru) 2015-03-23 2020-02-18 Санофи-Авентис Дойчланд Гмбх Корпус для инъекционного устройства и взаимное соединение деталей корпуса
US10773027B2 (en) 2015-03-23 2020-09-15 Sanofi-Aventis Deutschland Gmbh Injection Device
AU2016235054B2 (en) 2015-03-24 2020-07-16 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
JP6471029B2 (ja) * 2015-04-10 2019-02-13 株式会社ダイセル 注射器
EP3085404A1 (en) 2015-04-21 2016-10-26 Sanofi-Aventis Deutschland GmbH Dosing mechanism and drug delivery device
WO2016169946A1 (en) 2015-04-23 2016-10-27 Sanofi-Aventis Deutschland Gmbh Drug delivery device and retaining member for a drug delivery device
EP3285841B1 (en) 2015-04-23 2019-03-13 Sanofi-Aventis Deutschland GmbH Drug delivery device and predetermined breaking member for a drug delivery device
CN107666930B (zh) * 2015-05-21 2020-10-02 伊莱利利公司 注射装置的具有两种模式齿轮部的驱动
US20180161510A1 (en) 2015-05-27 2018-06-14 Sanofi-Aventis Deutschland Gmbh Drug delivery device
WO2016188985A1 (en) 2015-05-27 2016-12-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device
US20180147364A1 (en) * 2015-05-28 2018-05-31 Novo Nordisk A/S Drug Delivery Device with Multifunctional Bias Structure
EP3302655B1 (en) 2015-06-01 2019-05-15 Novo Nordisk A/S A housing for a medical injection device
TW201707738A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 注射器支架及自動注射器（二）
US10426196B2 (en) * 2015-06-09 2019-10-01 Gofire, Inc. Portable vaporizer for dosing concentrate material
HUE050055T2 (hu) 2015-06-09 2020-11-30 Sanofi Aventis Deutschland Adatgyûjtõ berendezés befecskendezõeszközhöz erõsítésre
AU2016287571C1 (en) 2015-06-30 2021-12-23 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
WO2017013463A1 (en) * 2015-07-21 2017-01-26 Biocorp Production S.A. Dose control system for injectable-drug delivery devices and associated methods of use
DE202015006845U1 (de) * 2015-09-30 2016-01-15 Haselmeier Ag Injektionsgerät
DE202015006841U1 (de) 2015-09-30 2016-01-15 Haselmeier Ag Injektionsgerät
DE202015006842U1 (de) 2015-09-30 2016-01-15 Haselmeier Ag Injektionsgerät
AU2016330773A1 (en) 2015-09-30 2018-04-19 Charité-Universitätsmedizin Berlin Method of treating melanocortin-4 receptor pathway-associated disorders
EP3359227B1 (en) 2015-10-09 2020-08-05 Novo Nordisk A/S Drug delivery device with slim drive mechanism
EP3368105B1 (en) * 2015-10-30 2020-07-01 Novo Nordisk A/S Method of manufacturing prefilled drug delivery devices
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
PL227678B1 (pl) 2015-12-22 2018-01-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ
AU2017237899B2 (en) * 2016-03-21 2019-11-21 Eli Lilly And Company Medical delivery device with axially expandable drive member
EP3241580A1 (en) 2016-05-03 2017-11-08 Sanofi-Aventis Deutschland GmbH Housing for an injection device
EP3241581A1 (en) 2016-05-03 2017-11-08 Sanofi-Aventis Deutschland GmbH Non-releasable snap connection of cartridge holder to syringe
CN106039475B (zh) * 2016-05-18 2019-08-02 苏州鹏烨医疗科技有限公司 一种注射笔
CN105944186B (zh) * 2016-05-18 2019-08-02 苏州鹏烨医疗科技有限公司 一种注射笔
US10350348B2 (en) 2016-05-23 2019-07-16 Lifescan Ip Holdings, Llc Manually actuated infusion device with display
US10967133B2 (en) 2016-05-30 2021-04-06 Novo Nordisk A/S Mounting feature for accessory device
JP6940525B2 (ja) 2016-05-30 2021-09-29 ノボ・ノルデイスク・エー／エス ゼロ位置調節特徴を有する薬剤送達デバイス
USD820439S1 (en) 2016-06-13 2018-06-12 Carebay Europe Ltd. Medicament delivery device
USD820438S1 (en) 2016-06-13 2018-06-12 Carebay Europe Ltd. Medicament delivery device
USD802757S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
CN105909505B (zh) * 2016-06-29 2018-08-17 上海康德莱医疗器械股份有限公司 一种加药电子泵
WO2018002314A1 (en) 2016-07-01 2018-01-04 Sanofi Drug delivery device
PL3108914T3 (pl) 2016-07-07 2019-08-30 Copernicus Sp. Z O.O. Urządzenie wstrzykujące do podawania określonej liczby jednakowych dawek substancji płynnej
CN106110443B (zh) * 2016-07-20 2022-07-22 昆山翰尔西医疗器械有限公司 一种注射器
US10709845B2 (en) 2016-07-21 2020-07-14 Amgen Inc. Drug delivery device with a rotatable drive mechanism
US9636464B1 (en) 2016-08-01 2017-05-02 Innovative Precision Instruments Limited Drug delivery device and a drug information detection device
CN106389123B (zh) * 2016-10-21 2019-01-15 浙江瑞邦智能装备股份有限公司 一种新型注射器
EP3534992B1 (en) 2016-11-01 2020-12-30 Sanofi-Aventis Deutschland GmbH Supplementary device for an injection device
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
EP3548119B1 (en) 2016-12-01 2020-11-18 Novo Nordisk A/S Drug delivery device with clutch feature
US11357920B2 (en) 2016-12-07 2022-06-14 Sanofi Data collection device for attachment to an injection device
US10688244B2 (en) 2016-12-23 2020-06-23 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
EP3348298A1 (en) 2017-01-16 2018-07-18 Novo Nordisk A/S Drug delivery device with rotationally geared piston rod driver
KR20230084596A (ko) * 2017-02-28 2023-06-13 일라이 릴리 앤드 캄파니 약제 전달 장치를 위한 투여 검출 및 약물 식별
CN110402158B (zh) 2017-03-14 2022-10-18 赛诺菲 具有声学反馈组件的注射装置
US11400227B2 (en) * 2017-04-07 2022-08-02 Novo Nordisk A/S End-of-content mechanism
JP6670270B2 (ja) * 2017-06-05 2020-03-18 金井　秀樹 薬液注入器及び薬液注入器に付設する薬液吐出量増大防止具
US10688247B2 (en) * 2017-07-13 2020-06-23 Haselmeier Ag Injection device with flexible dose selection
PL232651B1 (pl) 2017-07-18 2019-07-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Sprzęgło z systemem blokowania dla medycznego urządzenia wstrzykującego
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
CN114259626B (zh) 2017-08-30 2024-06-21 比罗埃特医药公司 紧凑型自动注射器
US11986639B2 (en) 2017-09-22 2024-05-21 Novo Nordisk A/S Accessory device for drug delivery device
WO2019071129A1 (en) 2017-10-05 2019-04-11 Pirouette Medical LLC PROTECTIVE HOUSING FOR A SELF-INJECTOR
CN111295215B (zh) 2017-11-07 2022-08-26 赛诺菲-安万特德国有限公司 注射装置
EP3706829A1 (en) 2017-11-07 2020-09-16 Sanofi-Aventis Deutschland GmbH Injection device with a preselector
CN111295213A (zh) 2017-11-07 2020-06-16 赛诺菲-安万特德国有限公司 具有剂量限制器的注射装置
WO2019091881A1 (en) 2017-11-07 2019-05-16 Sanofi-Aventis Deutschland Gmbh Injection device with a preselector
EP3706836A1 (en) 2017-11-07 2020-09-16 Sanofi-Aventis Deutschland GmbH Injection device with a preselector
US11684722B2 (en) 2017-12-04 2023-06-27 Novo Nordisk A/S Drug delivery system with multipolar magnet and sensor system
EP3495008A1 (en) 2017-12-06 2019-06-12 Sanofi Wind-up servo-actuator and drug delivery device
WO2019121448A1 (en) 2017-12-18 2019-06-27 Sanofi Rotation sensor for an injection device
WO2019121616A1 (en) 2017-12-21 2019-06-27 Sanofi Rfid dose tracking mechanism for injection devices
CN115487380A (zh) 2017-12-21 2022-12-20 赛诺菲 使用无源rf调制的与注射装置使用相关的数据的传输
CN111712278B (zh) 2017-12-21 2022-10-18 赛诺菲 用于注射装置的rfid剂量跟踪机构
FI3755404T3 (fi) 2018-02-22 2023-10-31 Lilly Co Eli Annoksentunnistusjärjestelmämoduuli lääkkeenjakelulaitteeseen
WO2019219797A1 (en) 2018-05-17 2019-11-21 Sanofi Touch sensitive label for an injection device
US20210220562A1 (en) * 2018-05-18 2021-07-22 Novo Nordisk A/S Sensor assembly with identifier determination
US11969583B2 (en) 2018-07-17 2024-04-30 Medmix Switzerland Ag Injection device with dose interruption fail safe
EP3597233A1 (en) * 2018-07-18 2020-01-22 Sanofi Drug delivery devices
CN111084918A (zh) * 2018-10-24 2020-05-01 群康生技股份有限公司 具有注射剂量调整功能的注射器
CN113056299B (zh) 2018-11-23 2023-11-03 赛诺菲 用于药物递送装置的电子墨水标签
WO2020115031A1 (en) * 2018-12-04 2020-06-11 Novo Nordisk A/S Drug delivery assembly with moving sensor system
EP3890806A1 (en) 2018-12-04 2021-10-13 Sanofi Assembly for a drug delivery device, drug delivery device, and method for producing a drug delivery device
CN113195020B (zh) 2018-12-18 2023-08-18 赛诺菲 注射装置和检测器组件
JP2022550650A (ja) 2019-04-18 2022-12-05 サノフイ 注射デバイスから送達される薬剤の用量を検出する装置
CN114144214A (zh) 2019-05-03 2022-03-04 赛诺菲 用于注射装置的旋转感测组件
US20220226583A1 (en) 2019-06-13 2022-07-21 Sanofi Apparatus for Detecting a Dose of Medicament Delivered from an Injection Device
EP3990059A1 (en) 2019-06-26 2022-05-04 Sanofi Injection device with a filling level indicator
US11167087B2 (en) 2019-08-09 2021-11-09 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
EP4052247A2 (en) 2019-10-28 2022-09-07 Sanofi Label for an injection device
US20230108921A1 (en) 2019-10-28 2023-04-06 Sanofi Electronic Label for a Drug Delivery Device
WO2021102700A1 (en) * 2019-11-26 2021-06-03 Sanofi Dose-recording device
RU197124U1 (ru) * 2019-12-20 2020-04-02 Общество с ограниченной ответственностью "Научно-производственный Инновационный внедренческий центр" Одноразовый картридж для ингалятора
EP4081282A1 (en) 2019-12-27 2022-11-02 Sanofi Apparatus for detecting a manipulation of an injection device
IL294521A (en) 2020-02-18 2022-09-01 Novo Nordisk As glp-1 compounds and their uses
US20230145686A1 (en) 2020-04-23 2023-05-11 Sanofi Drug Delivery Device
EP4138964A1 (en) 2020-04-23 2023-03-01 Sanofi Injection device with an electronic detector
WO2021233754A1 (en) 2020-05-18 2021-11-25 Novo Nordisk A/S Drug delivery device with click sound during delivery
WO2021239933A1 (en) 2020-05-29 2021-12-02 Sanofi Applicator device and applicator system for medicament containers
JP2023530005A (ja) 2020-06-19 2023-07-12 サノフイ ウェアラブル電子デバイス
USD958834S1 (en) * 2020-07-30 2022-07-26 Sanofi Display panel portion with an animated computer icon
USD953366S1 (en) * 2020-07-30 2022-05-31 Sanofi Display panel portion with an animated computer icon
USD958183S1 (en) * 2020-07-30 2022-07-19 Sanofi Display panel portion with an animated computer icon
USD953367S1 (en) * 2020-07-30 2022-05-31 Sanofi Display panel portion with an animated computer icon
USD947889S1 (en) * 2020-07-30 2022-04-05 Sanofi Display panel portion with an animated computer icon
USD952675S1 (en) * 2020-07-30 2022-05-24 Sanofi Display panel portion with an animated computer icon
USD953368S1 (en) * 2020-07-30 2022-05-31 Sanofi Display panel portion with an animated computer icon
USD952674S1 (en) * 2020-07-30 2022-05-24 Sanofi Display panel portion with an animated computer icon
USD949195S1 (en) * 2020-07-30 2022-04-19 Sanofi Display panel portion with an animated computer icon
CN116635096A (zh) 2021-01-04 2023-08-22 赛诺菲 包括放大器的注射装置壳体部件
JP2024505592A (ja) 2021-02-09 2024-02-06 サノフイ 用量計数システム
EP4291271A1 (en) 2021-02-09 2023-12-20 Sanofi Dose counting system
EP4070832A1 (en) 2021-04-07 2022-10-12 medmix Switzerland AG Keyed connectors
US20240198010A1 (en) 2021-04-23 2024-06-20 Sanofi Electronic System for a Drug Delivery Device
CN117120124A (zh) 2021-05-03 2023-11-24 赛诺菲 用于注射装置的经编码壳体部件
US20240207518A1 (en) 2021-05-03 2024-06-27 Sanofi Housing Components for an Injection Device
EP4333942A1 (en) 2021-05-03 2024-03-13 Sanofi Housing components and medicament container for an injection device
WO2022233751A1 (en) 2021-05-03 2022-11-10 Sanofi Coded housing components for an injection device
WO2022233755A1 (en) 2021-05-03 2022-11-10 Sanofi Housing components for an injection device
WO2022233753A1 (en) 2021-05-03 2022-11-10 Sanofi Coded housing components for an injection device
CN117177787A (zh) 2021-05-03 2023-12-05 赛诺菲 用于注射装置的经编码壳体部件
USD1039567S1 (en) * 2021-09-06 2024-08-20 Roche Diabetes Care, Inc. Display screen or portion thereof with a graphical user interface
EP4405006A1 (en) 2021-09-24 2024-07-31 Sanofi Information recording in a drug delivery device
EP4405008A1 (en) 2021-09-24 2024-07-31 Sanofi Dosing operation speed detection with electronic system for a drug delivery device
CN118354804A (zh) 2021-09-24 2024-07-16 赛诺菲 电子系统、用户接口构件、药物递送装置、以及用于检测药物递送装置是否暴露于或曾经暴露于流体的方法
CN117957029A (zh) 2021-09-24 2024-04-30 赛诺菲 被提供用于药物递送装置或药物递送附加装置的具有电池寿命优化的电子装置
JP2024533663A (ja) 2021-09-24 2024-09-12 サノフイ 薬物送達装置又は薬物送達付属装置のセンサの少なくとも１つの閾値の調整
CN117981007A (zh) 2021-09-24 2024-05-03 赛诺菲 确定与药物递送装置的寿命结束的接近有关的数据
CN117957030A (zh) 2021-09-24 2024-04-30 赛诺菲 对药物递送装置或药物递送附加装置的传感器的检查
WO2023046798A1 (en) 2021-09-24 2023-03-30 Sanofi Electronic component for a drug delivery device
EP4405981A1 (en) 2021-09-24 2024-07-31 Sanofi Data storage on a drug delivery device or on a drug delivery add-on device
WO2023046797A1 (en) 2021-09-24 2023-03-30 Sanofi Electronic module, drug delivery device and method for operating an electronic module
JP2024534563A (ja) 2021-09-24 2024-09-20 サノフイ 薬物送達装置又は薬物送達付属装置のセンサの制御
CN118251249A (zh) 2021-09-24 2024-06-25 赛诺菲 用于药物递送装置的部件以及药物递送装置
CN118251250A (zh) 2021-09-24 2024-06-25 赛诺菲 用于药物递送装置的用户接口构件以及药物递送装置
EP4406266A1 (en) 2021-09-24 2024-07-31 Sanofi Electronic module, drug delivery device and method for operating an electronic module
JP2024533664A (ja) 2021-09-24 2024-09-12 サノフイ 薬物送達装置又は薬物送達付属装置の光センサの駆動
EP4405000A1 (en) 2021-09-24 2024-07-31 Sanofi Operating an electronic unit of a drug delivery device or a drug delivery add-on device
EP4426382A1 (en) 2021-11-03 2024-09-11 Sanofi Drug delivery device and electronic unit
CN118234527A (zh) 2021-11-03 2024-06-21 赛诺菲 注射装置及注射装置的解锁操作方法
CN118176037A (zh) 2021-11-03 2024-06-11 赛诺菲 注射装置和解锁注射装置的操作的方法
CN118201661A (zh) 2021-11-03 2024-06-14 赛诺菲 用于药物递送装置的电子单元和移动电子装置
EP4426388A1 (en) 2021-11-03 2024-09-11 Sanofi Drug delivery device and electronic unit
EP4427156A1 (en) 2021-11-03 2024-09-11 Sanofi User authentication for a drug delivery device
CN118159185A (zh) 2021-11-03 2024-06-07 赛诺菲 用于药物输送装置的用户认证
WO2023078853A1 (en) 2021-11-03 2023-05-11 Sanofi Injection device and method of unlocking operation of the injection device
CN118201666A (zh) 2021-11-03 2024-06-14 赛诺菲 具有集成的锁定机构的补充装置
WO2023099514A1 (en) 2021-12-01 2023-06-08 Sanofi Drug delivery device and dose recording system herewith
EP4440664A1 (en) 2021-12-01 2024-10-09 Sanofi Drug delivery device and dose recording system herewith
WO2023099512A1 (en) 2021-12-01 2023-06-08 Sanofi Drug delivery device and dose recording system herewith
EP4440665A1 (en) 2021-12-01 2024-10-09 Sanofi Drug delivery device and dose recording system herewith
CN118647419A (zh) 2022-01-10 2024-09-13 赛诺菲 用于药物递送装置的携带箱体以及药物递送装置
WO2023152215A1 (en) 2022-02-11 2023-08-17 Sanofi Electrical system for a drug delivery device and drug delivery device
WO2023213756A1 (en) 2022-05-03 2023-11-09 Sanofi Sensor assembly for an injection device
WO2023213755A1 (en) 2022-05-03 2023-11-09 Sanofi Sensor assembly for detecting or recognizing operation an injection device
WO2023238017A1 (en) * 2022-06-08 2023-12-14 Zydus Lifesciences Limited Reusable multi-dose, variable dose, single pen injector for type 2 diabetes and weight management
WO2023237584A1 (en) 2022-06-09 2023-12-14 Sanofi Spacer for an add-on device
WO2024046934A1 (en) 2022-08-30 2024-03-07 Sanofi Injection device with add-on device
WO2024046935A1 (en) 2022-08-30 2024-03-07 Sanofi Add-on device for an injection device
WO2024046931A1 (en) 2022-08-30 2024-03-07 Sanofi Injection device and add-on device
WO2024046933A1 (en) 2022-08-30 2024-03-07 Sanofi Injection device and add-on device
WO2024046932A1 (en) 2022-08-30 2024-03-07 Sanofi Add-on device for an injection device
WO2024074519A1 (en) 2022-10-04 2024-04-11 Sanofi Injection device and method of preparing an injection device for injection
WO2024175629A1 (en) 2023-02-22 2024-08-29 Sanofi Injection simulation device
PL444242A1 (pl) * 2023-03-28 2024-09-30 Nemera Szczecin Spółka Z Ograniczoną Odpowiedzialnością Urządzenie do wstrzykiwania leku

Family Cites Families (258)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US533575A (en) 1895-02-05 wilkens
US2444570A (en) 1948-07-06 Drive for counter numeral wheels
US186463A (en) 1877-01-23 Improvement in flooring
GB304822A (en) 1927-10-26 1929-01-28 Gramophone Co Ltd Improvements in and relating to sound reproducing means
US2454583A (en) 1945-06-21 1948-11-23 Wisely Robert Grating structure
US2722931A (en) 1951-01-17 1955-11-08 Becton Dickinson Co Injection device
GB735433A (en) 1952-04-21 1955-08-24 Atomic Energy Authority Uk Improvements in or relating to columns for liquid-liquid extraction and like processes and packings for such columns
GB735443A (en) 1952-09-02 1955-08-24 English Numbering Machines Improvements in or relating to counting devices
US2717597A (en) 1952-12-04 1955-09-13 Jr George N Hein Injection apparatus
GB883769A (en) 1959-09-24 1961-12-06 British Drug Houses Ltd 3ª-:16ª-:17ª--trihydroxy steroids
CH499734A (de) 1968-07-19 1970-11-30 Kienzle Apparate Gmbh Klinkengesperre als Einrichtungs- und Überholkupplung
US3815785A (en) 1972-12-04 1974-06-11 Gilmont R Instr Inc Micrometric dispenser with calibration means
US4048960A (en) 1976-05-05 1977-09-20 Danforth Agri-Resources Slotted surface flooring for use in animal husbandry
AU510597B2 (en) 1976-06-11 1980-07-03 Yelverton Williams Patrick Split nut
US4231325A (en) 1979-06-06 1980-11-04 Parks Donald Merle Modular, waste collecting and draining floor apparatus
FR2467149A1 (fr) 1979-10-12 1981-04-17 Lorscheidt Willy Distributeur-doseur pour produits pateux et liquides
GB2109690B (en) * 1981-02-12 1985-02-20 Robert Charles Turner Dose metering plunger devices for use with syringes
US4568335A (en) 1981-08-28 1986-02-04 Markwell Medical Institute, Inc. Device for the controlled infusion of medications
DE3204178C2 (de) 1982-02-06 1986-03-20 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Pipettiervorrichtung
GB2141799B (en) 1983-06-03 1986-07-16 Diehl Gmbh & Co An adjusting ratchet mechanism for a time switch
DE3468173D1 (en) 1983-09-07 1988-02-04 Disetronic Ag Portable infusion apparatus
US4592754A (en) 1983-09-09 1986-06-03 Gupte Pradeep M Surgical prosthetic vessel graft and catheter combination and method
US4592745A (en) * 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
FR2583291A1 (fr) 1985-06-14 1986-12-19 Hazon Bernard Dispositif d'avancement pas a pas du piston de seringues par double vis coaxiale avec controle du debit d'injection. application aux injections medicamenteuses intra-dermiques repetitives
DE3670768D1 (de) 1985-11-08 1990-06-07 Disetronic Ag Injektionsgeraet.
DE3609555A1 (de) 1986-03-21 1987-09-24 Josef Porner Blutentnahmespritze
US5716990A (en) 1987-03-09 1998-02-10 Cancer Research Campaign Technology Limited Drug delivery systems
DK177187A (da) 1987-04-07 1988-10-08 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glasampul
DE3715340C2 (de) 1987-05-08 1995-10-19 Haselmeier Wilhelm Fa Injektionsgerät
DE3715258C2 (de) 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US4863072A (en) * 1987-08-18 1989-09-05 Robert Perler Single hand operable dental composite package
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US4833379A (en) 1988-01-13 1989-05-23 Sherwood Medical Company Motor control fail-safe circuit
CH675078A5 (pt) 1988-01-22 1990-08-31 Nosta Ag
US4973318A (en) * 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
DK166948B1 (da) 1988-02-10 1993-08-09 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule
DE3821969C1 (pt) 1988-06-29 1990-02-01 Michael Dr. 8000 Muenchen De Spaeth
DE58908873D1 (de) 1988-09-12 1995-02-23 Graesslin Kg Richtgesperre für eine Schaltuhr.
US5030209A (en) 1988-11-09 1991-07-09 Medical Safety Products, Inc. Holder for double ended blood collection retractable needle
DE68921856T2 (de) 1988-12-20 1995-12-07 Toshiba Kawasaki Kk Weichmagnetische auf Fe-basierende Legierung.
DK68789A (da) 1989-02-14 1990-08-15 Novo Nordisk As Injektionspen
US5000650A (en) 1989-05-12 1991-03-19 J.I. Case Company Automatic return to travel
US4994033A (en) 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
US5226895A (en) 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
DK17890A (da) 1990-01-22 1991-07-23 Novo Nordisk As Fremgangsmaade og apparat til opblanding og injicering af et laegemiddel
GB9007113D0 (en) 1990-03-29 1990-05-30 Sams Bernard Dispensing device
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5492534A (en) 1990-04-02 1996-02-20 Pharmetrix Corporation Controlled release portable pump
US5318540A (en) 1990-04-02 1994-06-07 Pharmetrix Corporation Controlled release infusion device
US5226896A (en) 1990-04-04 1993-07-13 Eli Lilly And Company Dose indicating injection pen
US5257987A (en) 1990-05-21 1993-11-02 Pharmetrix Corporation Controlled release osmotic infusion system
US5107190A (en) 1990-06-22 1992-04-21 Motorola, Inc. Means and method for optimizing the switching performance of power amplifiers
JP3042710B2 (ja) 1990-09-21 2000-05-22 ノボ ノルディスク アクティーゼルスカブ ペンシリンジアセンブリー
US5284480A (en) 1990-11-09 1994-02-08 Medtronic, Inc. Inflation/deflation syringe with threaded plunger
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
US5331954A (en) 1990-12-21 1994-07-26 Novo Nordisk A/S Device for nasal delivery of liquid medications
AU641206B2 (en) 1991-01-22 1993-09-16 Eli Lilly And Company Multiple dose injection pen
EP0498737B1 (en) 1991-02-07 1995-07-19 Terumo Kabushiki Kaisha Dosing means for an injector
IT221762Z2 (it) 1991-03-25 1994-10-20 Salvatore Sapienza Siringa opaca
DE4112259A1 (de) 1991-04-15 1992-10-22 Medico Dev Investment Co Injektionsgeraet
DK68991D0 (da) 1991-04-17 1991-04-17 Novo Nordisk As Manifold
US5645052A (en) 1991-04-26 1997-07-08 The Boc Group Plc Anaesthetic vaporizer with expandable/contractable reservoir for pumping liquid anaesthetic
GB9109832D0 (en) 1991-05-07 1991-06-26 Ellis Glynn A Saw blade machining system
EP0525525B1 (de) 1991-07-24 1995-05-03 Medico Development Investment Company Injektor
DK175491D0 (da) * 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5328486A (en) * 1991-11-19 1994-07-12 American Cyanamid Company Syringe for dispensing multiple dosages
US5611783A (en) 1991-11-29 1997-03-18 Novo Nordisk A/S Pen-shaped syringe
DK194291D0 (da) 1991-11-29 1991-11-29 Novo Nordisk As Sproejte til automatisk injektion.
US5246417A (en) 1991-12-11 1993-09-21 Alza Corporation Indicator for iontophoresis system
US5279585A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
CH682806A5 (de) 1992-02-21 1993-11-30 Medimpex Ets Injektionsgerät.
EP0632734B1 (en) 1992-03-25 1998-06-10 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
US5271527A (en) 1992-04-02 1993-12-21 Habley Medical Technology Corporation Reusable pharmaceutical dispenser with full stroke indicator
US5281198A (en) 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
US5300041A (en) 1992-06-01 1994-04-05 Habley Medical Technology Corporation Dose setting and repeating syringe
UA26190C2 (uk) 1992-07-28 1999-07-19 Сейфтек Ай Лімітед Шприц
GB9219849D0 (en) 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
ES2154651T3 (es) 1992-10-15 2001-04-16 Gen Hospital Corp Bomba de infusion con biblioteca de medicamentos cargable electronicamente.
US5545147A (en) 1992-10-20 1996-08-13 Eli Lilly And Company Anti-backup improvement for hypodermic syringes
US5391157A (en) 1992-10-20 1995-02-21 Eli Lilly And Company End of dose indicator
US5378233A (en) 1992-11-18 1995-01-03 Habley Medical Technology Corporation Selected dose pharmaceutical dispenser
US5547131A (en) 1992-12-04 1996-08-20 Bespak Plc Dispensing device with spray nozzle and driven piston
US5320609A (en) * 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
GB9226423D0 (en) * 1992-12-18 1993-02-10 Sams Bernard Incrementing mechanisms
FR2701211B1 (fr) 1993-02-08 1995-05-24 Aguettant Lab Instrument doseur, notamment d'injection
CZ284900B6 (cs) 1993-02-19 1999-04-14 Medicorp Holding S.A. Předem naplněná stříkačka pro uložení a vydávání kapalné a sterilní léčebné látky
US5383865A (en) 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
ZA941881B (en) 1993-04-02 1995-09-18 Lilly Co Eli Manifold medication injection apparatus and method
US5584815A (en) 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
US5591135A (en) 1993-04-12 1997-01-07 Sullivan; James J. Syringe stroke controller with elastically enabled single axis slide adjustment and finger-molded pistol grip
SE9301494D0 (sv) * 1993-04-30 1993-04-30 Kabi Pharmacia Ab A device for dosing liquid preparation
SE9303568D0 (sv) 1993-10-29 1993-10-29 Kabi Pharmacia Ab Improvements in injection devices
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
EP0667469A1 (en) 1994-02-14 1995-08-16 Akram Fado Ratchet mechanism exploiting both strokes of the ratchet motion
US5514097A (en) 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
US5562623A (en) 1994-02-14 1996-10-08 Univec Single-use syringe assembly including spring clip lock and plunger
US5536249A (en) * 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5634300A (en) 1994-03-10 1997-06-03 Plascore Inc. Wall system employing grooved posts, connector blocks and T-bolt receiving battens
AU1595395A (en) 1994-06-15 1996-01-05 Interventional Research Technologies, Inc. Locking device for syringe or like instrument
US5725508A (en) * 1994-06-22 1998-03-10 Becton Dickinson And Company Quick connect medication delivery pen
US5827232A (en) 1994-06-22 1998-10-27 Becton Dickinson And Company Quick connect medication delivery pen
US5440976A (en) 1994-08-23 1995-08-15 Fred Giuliano Adjustable dispensing stirrer for soluble sweeteners
CA2186869A1 (en) 1994-08-24 1996-02-29 Hideto Yamagata Injection apparatus
US5549574A (en) 1994-08-30 1996-08-27 Eli Lilly And Company Cartridge assembly for use in a pen-type medicament injector
US5549575A (en) 1994-09-13 1996-08-27 Becton Dickinson And Company Cartridge retainer assembly for medication delivery pen
US5582598A (en) 1994-09-19 1996-12-10 Becton Dickinson And Company Medication delivery pen with variable increment dose scale
BR9508847A (pt) 1994-09-20 1999-11-30 Novo Nordisk A S E Slagterisel Processo para tratar uma solução aquosa de proteìna e para produzir um gênero alimentìcio à base de carne, mistura de solução de proteìna/hidrolisado tratada com calor, ou hidrolisado lìquido tratado com calor, gênero alimentìcio à base de carne e uso da mistura de solução de proteìna/hidrolisado tratada com calor, ou de hidrolisado lìquido tratado com calor
ZA958073B (en) 1994-09-28 1996-04-23 Anthony William Manicom Method of and apparatus for administering a drug to a patient
US5690618A (en) 1995-02-22 1997-11-25 Mark Timothy Smith Electronic syringe
GB9503969D0 (en) 1995-02-28 1995-04-19 Sams Bernard Incrementing mechanism
CA2213682C (en) 1995-03-07 2009-10-06 Eli Lilly And Company Recyclable medication dispensing device
US5503628A (en) 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
US5562047A (en) 1995-05-19 1996-10-08 New Pig Corporation Modular spill deck
DK0840628T3 (da) 1995-06-02 2002-10-07 Novo Nordisk As Automatisk tilbagetrækning af stempelstang
US5882598A (en) * 1995-06-09 1999-03-16 Scp Global Technologies Wafer gap conductivity cell for characterizing process vessels and semiconductor fabrication processes and method of use
AU1860697A (en) 1995-09-08 1997-07-28 Visionary Medical Products Corporation Pen-type injector drive mechanism
US5674204A (en) * 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5688251A (en) * 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
DE59509694D1 (de) 1995-11-09 2001-11-15 Disetronic Licensing Ag Injektionsvorrichtung zur Aufnahme eines flüssigen Medikaments
US5692640A (en) 1995-12-05 1997-12-02 Caulfield; Patricia E. Syringe content identification system
US5899879A (en) * 1995-12-19 1999-05-04 Genesis Medical Technologies, Inc. Spring-actuated needleless injector
PL185539B1 (pl) 1996-02-23 2003-05-30 Novo Nordisk As Strzykawka z mechanizmem ustalania dawek i elektronicznym przedstawianiem parametrów
US6277098B1 (en) 1996-03-12 2001-08-21 Novo Nordisk A/S Injection device with electronic presentation of set doses
ATE224216T1 (de) * 1996-04-02 2002-10-15 Disetronic Licensing Ag Injektionsgerät
DE59609513D1 (de) 1996-04-02 2002-09-05 Disetronic Licensing Ag Injektionsgerät
CA2252620A1 (en) 1996-04-24 1997-10-30 Novo Nordisk A/S Injection needle
HUP9904152A3 (en) 1996-07-05 2000-05-29 Novo Nordisk As Flexible piston rod
CA2258308A1 (en) 1996-07-05 1998-01-15 Novo Nordisk A/S Dose setting device
WO1998001170A1 (en) 1996-07-05 1998-01-15 Novo Nordisk A/S Automatic needle insertion mechanism
US5709662A (en) 1996-08-23 1998-01-20 Becton Dickinson France, S.A. Cartridge for an injection device
US5843036A (en) 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
US6110149A (en) 1996-09-13 2000-08-29 Novo Nordisk A/S Syringe
JP3989966B2 (ja) 1996-09-13 2007-10-10 ノボ ノルディスク アクティーゼルスカブ 注入式注射器用投薬量ディスプレイ
US5947934A (en) 1996-09-13 1999-09-07 Novo Nordisk A/S Dose display for an injection syringe
US6379339B1 (en) 1996-09-13 2002-04-30 Nova Nordisk A/S Syringe
EP0927055B1 (en) 1996-09-20 2001-12-05 Novo Nordisk A/S Working cylinder
US6146361A (en) 1996-09-26 2000-11-14 Becton Dickinson And Company Medication delivery pen having a 31 gauge needle
US5851079A (en) 1996-10-25 1998-12-22 The Procter & Gamble Company Simplified undirectional twist-up dispensing device with incremental dosing
US5954689A (en) 1996-12-20 1999-09-21 Novo Nordisk A/S Jet injector
GB2321419B (en) 1997-01-27 2001-02-07 Medic Aid Ltd Atomizer
WO1998033538A1 (en) 1997-02-04 1998-08-06 Novo Nordisk A/S A device for the administration of a liquid medicament suspension
DE29703820U1 (de) 1997-03-03 1998-07-02 Medico Development Investment Co., Ascona Injektionsgerät
US5898028A (en) 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
US6277097B1 (en) 1997-03-25 2001-08-21 Novo Nordisk A/S Injection system
RU2111019C1 (ru) 1997-05-22 1998-05-20 Сергей Александрович Хворостов Универсальный инъектор
US6454746B1 (en) 1997-06-04 2002-09-24 Eli Lilly And Company Medication delivery apparatus
US6074372A (en) 1997-06-09 2000-06-13 Novo Nordisk A/S Dose setting mechanism and an injection syringe having such a dose setting mechanism
US6003736A (en) 1997-06-09 1999-12-21 Novo Nordisk A/S Device for controlled dispensing of a dose of a liquid contained in a cartridge
US6796970B1 (en) 1997-06-17 2004-09-28 Novo Nordisk A/S Dose setting device
US5961496A (en) 1997-06-17 1999-10-05 Novo Nordisk A/S Syringe with tiltable nut for quick piston disengagement
WO1999002210A1 (en) 1997-07-11 1999-01-21 Novo Nordisk A/S An apparatus for the registration of the setting of a medical device
JP2003514586A (ja) 1997-07-14 2003-04-22 ノボ ノルディスク アクティーゼルスカブ 円筒状アンプル
WO1999003521A1 (en) 1997-07-14 1999-01-28 Novo Nordisk A/S Injection member
DE19730999C1 (de) 1997-07-18 1998-12-10 Disetronic Licensing Ag Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
JPH1134710A (ja) 1997-07-24 1999-02-09 Bridgestone Corp 着座センサ付き座席
US5957896A (en) 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
FR2767479B1 (fr) 1997-08-22 1999-10-22 Aguettant Lab Dispositif d'injection de medicament
AU9202398A (en) 1997-09-29 1999-04-23 Becton Dickinson & Company Injection device and drug cartridge for preventing cross-use of the device and drug cartridge
US6312413B1 (en) 1997-10-30 2001-11-06 Novo Nordisk A/S Cylinder ampoule
ES2153711T3 (es) 1998-01-30 2001-03-01 Novo Nordisk As Jeringuilla de inyeccion.
US5961465A (en) 1998-02-10 1999-10-05 Hewlett-Packard Company Ultrasound signal processing electronics with active cooling
US6770288B2 (en) 1998-02-13 2004-08-03 Pfizer Products Inc. Drug delivery system
US6221053B1 (en) * 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US5961495A (en) 1998-02-20 1999-10-05 Becton, Dickinson And Company Medication delivery pen having a priming mechanism
US6248095B1 (en) * 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
AU4435399A (en) 1998-06-11 1999-12-30 Cerus Corporation Inhibiting proliferation of arterial smooth muscle cells
AU4769599A (en) 1998-07-08 2000-02-01 Novo Nordisk A/S A medical delivery device and a cartridge assembly for use in the same
US6033376A (en) 1998-09-30 2000-03-07 Allergan Sales, Inc. Wound shaper sleeve
US6605067B1 (en) 1998-11-20 2003-08-12 Novo Nordisk A/S Injection needle
DE19900827C1 (de) 1999-01-12 2000-08-17 Disetronic Licensing Ag Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
DE19900792C1 (de) 1999-01-12 2000-06-15 Disetronic Licensing Ag Vorrichtung zur Verabreichung eines injizierbaren Produkts
DE29900482U1 (de) 1999-01-14 2000-08-31 Medico Development Investment Co., Ascona Injektionsgerät
US6258062B1 (en) 1999-02-25 2001-07-10 Joseph M. Thielen Enclosed container power supply for a needleless injector
SE9901366D0 (sv) 1999-04-16 1999-04-16 Pharmacia & Upjohn Ab Injector device and method for its operation
ES2258469T3 (es) * 1999-08-05 2006-09-01 Becton Dickinson And Company Lapiz de administracion de medicacion.
US6277099B1 (en) 1999-08-06 2001-08-21 Becton, Dickinson And Company Medication delivery pen
US20020077582A1 (en) 1999-09-03 2002-06-20 Baxter International Inc. Blood processing systems and methods that assess and respond to real or potential vein occlusion conditions
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6514230B1 (en) 1999-10-12 2003-02-04 Novo Nordisk A/S Air shot mechanism for electronic injection devices
DE10052471B4 (de) * 1999-11-08 2012-08-23 Schaeffler Technologies Gmbh & Co. Kg Kegelscheibenumschlingungsgetriebe
TW450923B (en) 2000-01-11 2001-08-21 Procter & Gamble Reversibly collapsible/erectable container and method of using
US6379399B1 (en) 2000-02-16 2002-04-30 Bristol-Myers Squibb Company Oxidation hair dyeing systems and process for providing more equalized coloration on new and old growth hair
GB0007071D0 (en) * 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
AU2001252111A1 (en) 2000-05-04 2001-11-12 Novo-Nordisk A/S An injection device, a preassembled dose setting and injection mechanism for an injection device, and a method of assembling an injection device
US6692472B2 (en) 2000-05-04 2004-02-17 Novo Nordisk A/S Injection device, a preassembled dose setting and injection mechanism for an injection device, and a method of assembling an injection device
US6547763B2 (en) 2000-05-18 2003-04-15 Novo Nordisk A/S Dose display for injection device
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
US6547764B2 (en) 2000-05-31 2003-04-15 Novo Nordisk A/S Double pointed injection needle
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
ATE386563T1 (de) 2000-07-14 2008-03-15 Novo Nordisk As Flüssigkeitsabgabevorrichtung und verfahren zum vermindern des tröpfelns
WO2002024257A1 (en) 2000-09-22 2002-03-28 Novo Nordisk A/S A medication delivery device
NZ539404A (en) 2000-10-09 2007-05-31 Lilly Co Eli Pen device for administration of parathyroid hormone
JP2002143001A (ja) 2000-11-08 2002-05-21 Orugo Kk 容器の栓
US6899699B2 (en) 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
EP1361908B1 (en) 2001-02-14 2007-12-19 Novo Nordisk A/S Electronically controlled injection or infusion device
US20020165499A1 (en) 2001-04-13 2002-11-07 Slate John B. Jet injector having a mechanism for creating air-in-tip
EP1776975B1 (en) 2001-05-16 2011-06-22 Eli Lilly & Company Medication injector apparatus with drive assembly that facilitates reset
GB0113881D0 (en) 2001-06-07 2001-08-01 Innovate Biomed Ltd Foil cutting system
DE10163326A1 (de) 2001-07-30 2003-02-27 Disetronic Licensing Ag Verabreichungsgerät mit Dosiervorrichtung
GB0200444D0 (en) * 2002-01-10 2002-02-27 Owen Mumford Ltd Improvements relating to medical injection devices
GB2384431A (en) 2002-01-25 2003-07-30 Medical House Plc Needleless injector having an audible dose indicator
US6941948B2 (en) 2002-03-07 2005-09-13 Vectura Drug Delivery Medicament storage and delivery devices
GB0205485D0 (en) 2002-03-08 2002-04-24 Dca Design Int Ltd Improvements in and relating to a medicament delivery service
WO2003080160A1 (en) 2002-03-18 2003-10-02 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
JP4228586B2 (ja) 2002-05-21 2009-02-25 富士電機デバイステクノロジー株式会社 半導体装置
EP1521607A1 (en) 2002-07-10 2005-04-13 Novo Nordisk A/S An injection device with a dose setting limiter
US6945961B2 (en) 2002-07-10 2005-09-20 Novo Nordisk A/S Injection device
DE10232412A1 (de) * 2002-07-17 2004-02-05 Disetronic Licensing Ag Verabreichungsgerät mit Primingfunktion
EP1391794A1 (en) 2002-07-23 2004-02-25 Novo Nordisk A/S Device with time indicating means
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
ATE331542T1 (de) 2002-08-29 2006-07-15 Novo Nordisk As Injektionsvorrichtung mit frontladung
JP3906988B2 (ja) 2002-08-30 2007-04-18 日本電産サンキョー株式会社 モータ
EP1545663B1 (en) * 2002-10-01 2006-08-30 Becton Dickinson and Company Medication delivery pen
WO2004066939A2 (en) 2003-01-27 2004-08-12 Sarnoff Corporation Controlled-release drug delivery system
US9205197B2 (en) 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
GB0304823D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304824D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US6923145B2 (en) 2003-03-20 2005-08-02 Michael Wahl Flume flush floor for livestock
GB0306642D0 (en) 2003-03-22 2003-04-30 Dca Design Int Ltd Improvements in and relating to an injector for a medical product
US6932794B2 (en) * 2003-04-03 2005-08-23 Becton, Dickinson And Company Medication delivery pen
GB0308267D0 (en) 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
SI1656170T1 (sl) * 2003-08-12 2019-05-31 Eli Lilly And Company Oprema za izdajanje zdravil s trojnim vijačnim navojem za mehanski pospešek
EP1541185A1 (en) 2003-12-08 2005-06-15 Novo Nordisk A/S Automatic syringe with priming mechanism
US7448385B2 (en) 2004-06-07 2008-11-11 Purepharm Inc. Nasal adaptation of an oral inhaler device
US7690160B2 (en) 2004-07-23 2010-04-06 Moller Jr Jorgen J Modular floor tile system with transition edge
EP1642607A1 (en) * 2004-10-04 2006-04-05 Sanofi-Aventis Deutschland GmbH Dose display mechanism for a drug delivery device
NZ554384A (en) * 2004-10-04 2010-04-30 Sanofi Aventis Deutschland Drive mechanism for drug delivery device
EP1645301A1 (en) 2004-10-11 2006-04-12 Novo Nordisk A/S Injection device
DE602005026595D1 (de) 2004-12-01 2011-04-07 Novo Nordisk As Injektionsvorrichtung
DE102004063645A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel
JP4970286B2 (ja) 2005-02-11 2012-07-04 ノボ・ノルデイスク・エー／エス 注入器具
DE602006004314D1 (de) 2005-02-28 2009-01-29 Novo Nordisk As Dosiseinstellmechanismus für eine injektionsvorrichtung, mit der eine höchstdosis voreingestellt werden kann
CN101163514B (zh) 2005-04-24 2012-01-25 诺和诺德公司 注射装置
US9011386B2 (en) * 2005-06-01 2015-04-21 Shl Group Ab Device for delivering medicament
WO2007006662A1 (en) * 2005-07-08 2007-01-18 Novo Nordisk A/S Injection device
USD533575S1 (en) 2006-01-03 2006-12-12 Creative Technology Ltd Camera
US7490443B1 (en) 2006-03-01 2009-02-17 Bike Track, Inc. Modular flooring system
EP2083888A1 (en) 2006-11-17 2009-08-05 Novo Nordisk A/S A medical delivery system comprising a coding mechanism between dosing assembly and medicament container
ES2488667T3 (es) 2007-01-22 2014-08-28 Teva Pharmaceutical Industries Ltd Jeringa que tiene una etiqueta de jeringa
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8267900B2 (en) 2008-05-02 2012-09-18 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8205398B2 (en) 2008-08-19 2012-06-26 Building Materials Investment Corp. Fascia vent
CA2647230A1 (en) 2008-12-17 2010-06-17 David Robert Hundeby Raised floor heating and cooling system for buildings
EP2401009B1 (de) 2009-02-26 2012-11-28 Tecpharma Licensing AG Produktbehältnishalter für eine injektionsvorrichtung und zur aufnahme eines produktbehältnisses
US8672896B2 (en) * 2009-06-01 2014-03-18 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
US8257319B2 (en) * 2009-06-01 2012-09-04 Sanofi-Aventis Deutschland Gmbh Drug delivery device inner housing having helical spline
KR101027514B1 (ko) 2009-06-15 2011-04-06 삼성전기주식회사 입력 장치
US9616175B2 (en) * 2009-07-08 2017-04-11 Novo Nordisk A/S Frost protected injection device
DK3170526T3 (da) 2009-10-30 2021-10-11 Sanofi Aventis Deutschland Patron til lægemiddeladministrationsanordning
US8517729B2 (en) 2010-03-04 2013-08-27 The University of Western Ontario and Trudell Medical International Oral mouthpiece and method for the use thereof
US8505131B2 (en) 2010-07-27 2013-08-13 Perimedrain Systems, LLC Trench drain system and method of installation on level floor surface, paticulary for shower rooms
TWI464003B (zh) * 2010-11-18 2014-12-11 Shl Group Ab 藥物輸送裝置
DK2688611T3 (en) * 2011-03-25 2015-07-27 Sanofi Aventis Deutschland Dose adjustment mechanism and injection device
JP6314139B2 (ja) * 2012-08-31 2018-04-18 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス
RU2015122657A (ru) 2012-11-13 2017-01-10 СЭЙФСПИЛЛ СИСТЕМЗ ЭлЭлСи Модульный противопожарный пол
DK2983735T3 (da) * 2013-04-10 2021-03-01 Sanofi Sa Drivmekanisme til en lægemiddeladministrationsanordning

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