PL4063397T3 - Chimeryczne receptory antygenowe oparte na przeciwciałach jednodomenowych i sposoby ich zastosowania - Google Patents

Chimeryczne receptory antygenowe oparte na przeciwciałach jednodomenowych i sposoby ich zastosowania

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Publication number
PL4063397T3
PL4063397T3 PL22168161.2T PL22168161T PL4063397T3 PL 4063397 T3 PL4063397 T3 PL 4063397T3 PL 22168161 T PL22168161 T PL 22168161T PL 4063397 T3 PL4063397 T3 PL 4063397T3
Authority
PL
Poland
Prior art keywords
methods
chimeric antigen
domain antibodies
antigen receptors
receptors based
Prior art date
Application number
PL22168161.2T
Other languages
English (en)
Inventor
Xiaohu FAN
Chuan-Chu Chou
Qiuchuan ZHUANG
Pingyan WANG
Lin Wang
Lei Yang
Jiaying HAO
Original Assignee
Legend Biotech Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Legend Biotech Ireland Limited filed Critical Legend Biotech Ireland Limited
Publication of PL4063397T3 publication Critical patent/PL4063397T3/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001116—Receptors for cytokines
    • A61K39/001117—Receptors for tumor necrosis factors [TNF], e.g. lymphotoxin receptor [LTR] or CD30
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
    • A61K40/4211—CD19 or B4
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    • A61K40/42—Cancer antigens
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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PL22168161.2T 2015-08-11 2016-08-10 Chimeryczne receptory antygenowe oparte na przeciwciałach jednodomenowych i sposoby ich zastosowania PL4063397T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510490002 2015-08-11
CN201510733585.2A CN105384825B (zh) 2015-08-11 2015-11-02 一种基于单域抗体的双特异性嵌合抗原受体及其应用

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PL4063397T3 true PL4063397T3 (pl) 2024-11-18

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PL22168161.2T PL4063397T3 (pl) 2015-08-11 2016-08-10 Chimeryczne receptory antygenowe oparte na przeciwciałach jednodomenowych i sposoby ich zastosowania
PL21166662.3T PL3896091T3 (pl) 2015-08-11 2017-08-10 Chimeryczne receptory antygenowe nakierowane na bcma i sposoby ich zastosowania

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