NO812542L - Nye trisubstituerte imidazolderivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse samt deres anvendelse - Google Patents

Nye trisubstituerte imidazolderivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse samt deres anvendelse

Info

Publication number
NO812542L
NO812542L NO812542A NO812542A NO812542L NO 812542 L NO812542 L NO 812542L NO 812542 A NO812542 A NO 812542A NO 812542 A NO812542 A NO 812542A NO 812542 L NO812542 L NO 812542L
Authority
NO
Norway
Prior art keywords
phenyl
formula
substituted
atoms
pyridyl
Prior art date
Application number
NO812542A
Other languages
English (en)
Norwegian (no)
Inventor
Alfred Sallmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO812542L publication Critical patent/NO812542L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
NO812542A 1980-07-25 1981-07-24 Nye trisubstituerte imidazolderivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse samt deres anvendelse NO812542L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH571580 1980-07-25

Publications (1)

Publication Number Publication Date
NO812542L true NO812542L (no) 1982-01-26

Family

ID=4298165

Family Applications (1)

Application Number Title Priority Date Filing Date
NO812542A NO812542L (no) 1980-07-25 1981-07-24 Nye trisubstituerte imidazolderivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse samt deres anvendelse

Country Status (23)

Country Link
US (1) US4447431A (enExample)
EP (1) EP0045081B1 (enExample)
JP (1) JPS5756466A (enExample)
KR (13) KR850000883B1 (enExample)
AR (1) AR230269A1 (enExample)
AT (1) ATE17349T1 (enExample)
AU (2) AU7340481A (enExample)
CA (1) CA1175431A (enExample)
DD (2) DD201677A5 (enExample)
DE (1) DE3173434D1 (enExample)
DK (1) DK331881A (enExample)
ES (8) ES8301472A1 (enExample)
FI (1) FI812326A7 (enExample)
GB (1) GB2080805B (enExample)
GR (1) GR75287B (enExample)
IE (1) IE52071B1 (enExample)
IL (1) IL63410A (enExample)
NO (1) NO812542L (enExample)
NZ (1) NZ197828A (enExample)
PL (8) PL236997A1 (enExample)
PT (1) PT73424B (enExample)
SU (8) SU1235454A3 (enExample)
ZA (1) ZA815078B (enExample)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002613A1 (fr) * 1981-07-20 1983-08-04 Sallmann, Alfred Composes oxazoiques a triple substitution
EP0084756A1 (de) * 1982-01-22 1983-08-03 Ciba-Geigy Ag Trisubstituierte Oxazaverbindungen
FR2633291B1 (fr) * 1988-06-27 1990-09-07 Oreal Derives d'hydroxy-4 isoxazoles, leur procede de preparation et compositions cosmetiques et pharmaceutiques les contenant
US5252322A (en) * 1989-09-22 1993-10-12 The Gillette Company Skin tanning compositions containing imidazoles
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
US5916891A (en) * 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
MX9300141A (es) * 1992-01-13 1994-07-29 Smithkline Beecham Corp Compuestos de imidazol novedosos, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
US5670527A (en) * 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
US5593991A (en) * 1993-07-16 1997-01-14 Adams; Jerry L. Imidazole compounds, use and process of making
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
JPH09505055A (ja) 1993-11-08 1997-05-20 スミスクライン・ビーチャム・コーポレイション サイトカイン媒介疾患治療用オキサゾール
US5723477A (en) * 1994-11-10 1998-03-03 Sibia Neurosciences, Inc. Modulators of acetylcholine receptors
IL118544A (en) 1995-06-07 2001-08-08 Smithkline Beecham Corp History of imidazole, the process for their preparation and the pharmaceutical preparations containing them
US6369068B1 (en) 1995-06-07 2002-04-09 Smithkline Beecham Corporation Amino substituted pyrimidine containing compounds
US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
ZA9610687B (en) 1995-12-22 1997-09-29 Smithkline Beecham Corp Novel synthesis.
US6046208A (en) * 1996-01-11 2000-04-04 Smithkline Beecham Corporation Substituted imidazole compounds
ZA97175B (en) * 1996-01-11 1997-11-04 Smithkline Beecham Corp Novel substituted imidazole compounds.
AP9700912A0 (en) 1996-01-11 1997-01-31 Smithkline Beecham Corp Novel cycloalkyl substituted imidazoles
NZ327044A (en) * 1996-01-11 2000-01-28 Smithkline Beecham Corp Substituted imidazole compounds
JP2000507558A (ja) * 1996-03-25 2000-06-20 スミスクライン・ビーチャム・コーポレイション Ｃｎｓ損傷についての新規な治療
WO1998007425A1 (en) 1996-08-21 1998-02-26 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
AU7138298A (en) * 1997-04-24 1998-11-13 Ortho-Mcneil Corporation, Inc. Substituted imidazoles useful in the treatment of inflammatory diseases
WO1998056377A1 (en) 1997-06-13 1998-12-17 Smithkline Beecham Corporation Novel pyrazole and pyrazoline substituted compounds
AU8154998A (en) 1997-06-19 1999-01-04 Smithkline Beecham Corporation Novel aryloxy substituted pyrimidine imidazole compounds
US6562832B1 (en) 1997-07-02 2003-05-13 Smithkline Beecham Corporation Substituted imidazole compounds
EP1019396A1 (en) 1997-07-02 2000-07-19 SmithKline Beecham Corporation Novel cycloalkyl substituted imidazoles
US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
US6489325B1 (en) 1998-07-01 2002-12-03 Smithkline Beecham Corporation Substituted imidazole compounds
TW517055B (en) 1997-07-02 2003-01-11 Smithkline Beecham Corp Novel substituted imidazole compounds
EP1041989A4 (en) 1997-10-08 2002-11-20 Smithkline Beecham Corp NEW SUBSTITUTED CYCLOALCENYL COMPOUNDS
AU1924699A (en) 1997-12-19 1999-07-12 Smithkline Beecham Corporation Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses
WO1999061437A1 (en) 1998-05-22 1999-12-02 Smithkline Beecham Corporation Novel 2-alkyl substituted imidazole compounds
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
US6599910B1 (en) * 1998-08-20 2003-07-29 Smithkline Beecham Corporation Substituted triazole compounds
JP2002528506A (ja) * 1998-11-04 2002-09-03 スミスクライン・ビーチャム・コーポレイション ピリジン−４−イルまたはピリミジン−４−イル置換ピラジン
WO2000029399A1 (en) * 1998-11-12 2000-05-25 Boehringer Ingelheim (Canada) Ltd. Antiherpes compounds
US6239279B1 (en) 1998-12-16 2001-05-29 Smithkline Beecham Corporation Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
IL149150A0 (en) 1999-11-22 2002-12-01 Smithkline Beecham Plc 2-(4-(6-methoxy-naphthalene-2-yl)-5-pyridin-4-yl-1h-imidazole-2-yl)-2-methyl-derivatives, pharmaceutical compositions comprising them and use thereof as tie2 receptor kinase inhibitors
ES2230171T3 (es) 1999-11-23 2005-05-01 Smithkline Beecham Corporation Compuestos 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de csbp/p38 quinasa.
WO2001038314A1 (en) 1999-11-23 2001-05-31 Smithkline Beecham Corporation 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
DE60023025T2 (de) 1999-11-23 2006-07-13 Smithkline Beecham Corp. 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
GB0005357D0 (en) 2000-03-06 2000-04-26 Smithkline Beecham Plc Compounds
AU2001235838A1 (en) * 2000-03-06 2001-09-17 Smithkline Beecham Plc Imidazol derivatives as raf kinase inhibitors
EP2404603A1 (en) * 2000-10-23 2012-01-11 Glaxosmithkline LLC Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds for the treatment of CSBP/p38 kinase mediated diseases
GB0112348D0 (en) * 2001-05-19 2001-07-11 Smithkline Beecham Plc Compounds
JP2005504793A (ja) * 2001-09-05 2005-02-17 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー Ｒａｆキナーゼ阻害剤としてのヘテロサイクルカルボキサミド誘導体
ES2307822T3 (es) * 2001-12-18 2008-12-01 F. Hoffmann-La Roche Ag Cis-imidazolinas como inhibidores de mdm2.
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox
CA2524889A1 (en) * 2003-05-08 2004-11-18 Astellas Pharma Inc. 1,2-diarylimidazoles useful as inhibitors of cox
US20080096905A1 (en) * 2005-03-25 2008-04-24 Glaxo Group Limited Process For Preparing Pyrido[2,3-D]Pyrimidin-7-One And 3,4-Dihydropyrimido{4,5-D}Pyrimidin-2(1H)-One Derivatives
TWI389690B (zh) 2005-03-25 2013-03-21 Glaxo Group Ltd 新穎化合物（一）
WO2013049272A2 (en) 2011-09-29 2013-04-04 Theraceutix, Llc Composition and method for treatment of symptoms associated with various skin conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558645A (en) * 1968-07-08 1971-01-26 Sandoz Ag 2-(4-(4',5-diphenyl - 2 - imidazolyl)-phenoxy) lower aliphatic monocarboxylic acids
CH561202A5 (enExample) * 1971-05-10 1975-04-30 Ciba Geigy Ag
GB1469532A (en) * 1973-06-28 1977-04-06 Dumex Ltd As Imimdazolyl-alkanoic acid derivatives
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols

Also Published As

Publication number Publication date
KR850002747A (ko) 1985-05-15
JPS5756466A (en) 1982-04-05
IE52071B1 (en) 1987-06-10
DK331881A (da) 1982-01-26
ES8306123A1 (es) 1983-05-16
SU1205764A3 (ru) 1986-01-15
PL237001A1 (en) 1983-02-28
ES514582A0 (es) 1983-05-16
IL63410A0 (en) 1981-10-30
KR850000891B1 (ko) 1985-06-26
AR230269A1 (es) 1984-03-01
KR850000886B1 (ko) 1985-06-26
KR850000873B1 (ko) 1985-06-22
KR830006230A (ko) 1983-09-20
PL232352A1 (enExample) 1982-12-20
KR850002745A (ko) 1985-05-15
SU1227112A3 (ru) 1986-04-23
FI812326L (fi) 1982-01-26
IL63410A (en) 1986-04-29
ES514580A0 (es) 1983-05-16
PL237000A1 (en) 1983-02-28
KR850002754A (ko) 1985-05-15
KR850001064B1 (ko) 1985-07-25
PT73424B (en) 1983-06-20
ES8306122A1 (es) 1983-05-16
GB2080805A (en) 1982-02-10
EP0045081A2 (de) 1982-02-03
DD202554A5 (de) 1983-09-21
KR850002749A (ko) 1985-05-15
PT73424A (en) 1981-08-01
ATE17349T1 (de) 1986-01-15
PL237005A1 (en) 1983-02-28
KR850000884B1 (ko) 1985-06-26
ES8306124A1 (es) 1983-05-16
KR850000883B1 (ko) 1985-06-26
ES514583A0 (es) 1983-05-16
PL237004A1 (en) 1983-02-28
SU1169534A3 (ru) 1985-07-23
FI812326A7 (fi) 1982-01-26
KR850002752A (ko) 1985-05-15
SU1205763A3 (ru) 1986-01-15
KR850002750A (ko) 1985-05-15
KR850000892B1 (ko) 1985-06-26
EP0045081B1 (de) 1986-01-08
KR850002748A (ko) 1985-05-15
ES504257A0 (es) 1982-12-01
KR850000889B1 (ko) 1985-06-26
SU1152520A3 (en) 1985-04-23
IE811680L (en) 1982-01-25
SU1138023A3 (ru) 1985-01-30
PL237003A1 (en) 1983-02-28
GB2080805B (en) 1984-03-07
KR850000888B1 (ko) 1985-06-26
ES514585A0 (es) 1983-07-01
PL135822B1 (en) 1985-12-31
KR850002753A (ko) 1985-05-15
KR850002744A (ko) 1985-05-15
CA1175431A (en) 1984-10-02
KR850000887B1 (ko) 1985-06-26
DE3173434D1 (en) 1986-02-20
ES8301472A1 (es) 1982-12-01
KR850000911B1 (ko) 1985-06-27
US4447431A (en) 1984-05-08
NZ197828A (en) 1985-11-08
ES514581A0 (es) 1983-05-16
KR850002756A (ko) 1985-05-15
ES8306120A1 (es) 1983-05-16
KR850000885B1 (ko) 1985-06-26
AU7340481A (en) 1982-01-28
SU1235454A3 (ru) 1986-05-30
ES8306119A1 (es) 1983-05-16
SU1145928A3 (ru) 1985-03-15
PL237002A1 (en) 1983-02-28
KR850002746A (ko) 1985-05-15
ES514579A0 (es) 1983-05-16
EP0045081A3 (en) 1982-04-07
ES8307245A1 (es) 1983-07-01
AU5655586A (en) 1986-09-11
KR850002755A (ko) 1985-05-15
DD201677A5 (de) 1983-08-03
ZA815078B (en) 1982-07-28
GR75287B (enExample) 1984-07-13
KR850000890B1 (ko) 1985-06-26
ES8306121A1 (es) 1983-05-16
PL236997A1 (en) 1983-01-03
ES514584A0 (es) 1983-05-16

Similar Documents

Publication Publication Date Title
NO812542L (no) Nye trisubstituerte imidazolderivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse samt deres anvendelse
KR900008566B1 (ko) 치환된 바이시클릭 화합물의 제조방법
EP0533837A1 (en) Inhibition of 5-lipoxygenase and cyclooxygenase pathway mediated diseases
AU778819B2 (en) 5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them
BRPI0618354A2 (pt) composto ou seu sal farmaceuticamente aceitável, antagonista do receptor-3 de histamina, agonista inverso do receptor-3 de histamina, preventivo ou remédio
US6900232B2 (en) Cycloalkyl alkanoic acids as integrin receptor antagonists
NO862618L (no) Nye pikolinderivater, fremgangsmaate ved fremstilling derav, anvendelse og medikamenter som inneholder dem.
NZ238576A (en) Pyridinone derivatives, preparation and pharmaceutical compositions thereof
JPH0153671B2 (enExample)
TW201422586A (zh) 經取代４－吡啶酮及其做爲嗜中性白血球彈性蛋白酶活性抑制劑之用途
JP4166991B2 (ja) ピリドピリミジンまたはナフチリジン誘導体
JPH05178840A (ja) ピリミジンの新誘導体、それらの製造法、得られる中間体、それらの薬剤としての使用及びそれらを含有する製薬組成物
JPH0471077B2 (enExample)
NZ194328A (en) 3-amino-1-(phenyl or pyridyl)-2-pyrazolines:pharmaceutical compositions
US7064207B2 (en) Androgen receptor antagonists
JP2006520780A (ja) アンドロゲン受容体アンタゴニストとしてのキノリンおよびクロメンの６−スルホンアミド誘導体
US4694018A (en) Substituted 1,5-diphenyl-2-pyrrolepropionic acids and derivatives
KR100273181B1 (ko) 신규 피리돈 유도체 그의 제조방법 그에 의해 얻어진 신규 중간체, 그의 의약으로서의 용도 및 그를 함유하는 제약 조성물
DE2360550A1 (de) Indenylaethyltetrazole, -sulfonsaeuren und -phosphorsaeuren
JPH06157543A (ja) 新規のチエノチアジン誘導体、その製造方法並びにその使用方法
NO812790L (no) Nye diaryl-imidazol-forbindelser, fremgangsmaate til deres fremstilling, farmasoeytiske preparater som inneholder disse og deres anvendelse
US3700691A (en) 3,3-disubstituted-3,4-dihydrobenzodioxepins
DK160049B (da) 6-phenethylaminoalkyl-furo-(3,4-c)-pyridin-derivater, og laegemidler indeholdende saadanne forbindelser
NO830611L (no) Imidazotiadiazolalkenkarboksylsyreamider, nye mellomprodukter til deres fremstilling, deres fremstilling og deres anvendles i legemidler
NO309037B1 (no) Substituerte aminoalkylaminopyridiner med virkning ovenfor Helicobacter pylori