KR850002749A - 삼-치환 이미다졸 유도체의 제조방법 - Google Patents

삼-치환 이미다졸 유도체의 제조방법

Info

Publication number
KR850002749A
KR850002749A KR1019840005965A KR840005965A KR850002749A KR 850002749 A KR850002749 A KR 850002749A KR 1019840005965 A KR1019840005965 A KR 1019840005965A KR 840005965 A KR840005965 A KR 840005965A KR 850002749 A KR850002749 A KR 850002749A
Authority
KR
South Korea
Prior art keywords
tri
preparing
imidazole derivative
substituted imidazole
substituted
Prior art date
Application number
KR1019840005965A
Other languages
English (en)
Other versions
KR850000888B1 (ko
Inventor
살만 알프레드
Original Assignee
시바-가이기 에이지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 시바-가이기 에이지 filed Critical 시바-가이기 에이지
Priority to KR1019840005965A priority Critical patent/KR850000888B1/ko
Publication of KR850002749A publication Critical patent/KR850002749A/ko
Application granted granted Critical
Publication of KR850000888B1 publication Critical patent/KR850000888B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
KR1019840005965A 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법 KR850000888B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840005965A KR850000888B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH571580 1980-07-25
CH5715 1980-07-25
KR1019810002709A KR850000883B1 (ko) 1980-07-25 1981-07-25 삼-치환 이미다졸 유도체의 제조방법
KR1019840005965A KR850000888B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002709A Division KR850000883B1 (ko) 1980-07-25 1981-07-25 삼-치환 이미다졸 유도체의 제조방법

Publications (2)

Publication Number Publication Date
KR850002749A true KR850002749A (ko) 1985-05-15
KR850000888B1 KR850000888B1 (ko) 1985-06-26

Family

ID=4298165

Family Applications (13)

Application Number Title Priority Date Filing Date
KR1019810002709A KR850000883B1 (ko) 1980-07-25 1981-07-25 삼-치환 이미다졸 유도체의 제조방법
KR1019840005971A KR850000892B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005962A KR850000885B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005972A KR850001064B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005964A KR850000887B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005961A KR850000884B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005965A KR850000888B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005960A KR850000873B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005970A KR850000911B1 (ko) 1980-07-25 1984-09-27 삼-치환 옥사졸 유도체의 제조방법
KR1019840005968A KR850000890B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005969A KR850000891B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005966A KR850000889B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005963A KR850000886B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법

Family Applications Before (6)

Application Number Title Priority Date Filing Date
KR1019810002709A KR850000883B1 (ko) 1980-07-25 1981-07-25 삼-치환 이미다졸 유도체의 제조방법
KR1019840005971A KR850000892B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005962A KR850000885B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005972A KR850001064B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005964A KR850000887B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005961A KR850000884B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법

Family Applications After (6)

Application Number Title Priority Date Filing Date
KR1019840005960A KR850000873B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005970A KR850000911B1 (ko) 1980-07-25 1984-09-27 삼-치환 옥사졸 유도체의 제조방법
KR1019840005968A KR850000890B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005969A KR850000891B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005966A KR850000889B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법
KR1019840005963A KR850000886B1 (ko) 1980-07-25 1984-09-27 삼-치환 이미다졸 유도체의 제조방법

Country Status (23)

Country Link
US (1) US4447431A (ko)
EP (1) EP0045081B1 (ko)
JP (1) JPS5756466A (ko)
KR (13) KR850000883B1 (ko)
AR (1) AR230269A1 (ko)
AT (1) ATE17349T1 (ko)
AU (2) AU7340481A (ko)
CA (1) CA1175431A (ko)
DD (2) DD201677A5 (ko)
DE (1) DE3173434D1 (ko)
DK (1) DK331881A (ko)
ES (8) ES504257A0 (ko)
FI (1) FI812326L (ko)
GB (1) GB2080805B (ko)
GR (1) GR75287B (ko)
IE (1) IE52071B1 (ko)
IL (1) IL63410A (ko)
NO (1) NO812542L (ko)
NZ (1) NZ197828A (ko)
PL (8) PL237004A1 (ko)
PT (1) PT73424B (ko)
SU (8) SU1235454A3 (ko)
ZA (1) ZA815078B (ko)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2123831B (en) * 1981-07-20 1986-01-15 Ciba Geigy Ag Trisubstituted oxazo compounds
EP0084756A1 (de) * 1982-01-22 1983-08-03 Ciba-Geigy Ag Trisubstituierte Oxazaverbindungen
FR2633291B1 (fr) * 1988-06-27 1990-09-07 Oreal Derives d'hydroxy-4 isoxazoles, leur procede de preparation et compositions cosmetiques et pharmaceutiques les contenant
US5252322A (en) * 1989-09-22 1993-10-12 The Gillette Company Skin tanning compositions containing imidazoles
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
US5670527A (en) * 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5593991A (en) * 1993-07-16 1997-01-14 Adams; Jerry L. Imidazole compounds, use and process of making
EP0727998B1 (en) * 1993-11-08 2004-01-21 Smithkline Beecham Corporation Oxazoles for treating cytokine mediated diseases
US5723477A (en) * 1994-11-10 1998-03-03 Sibia Neurosciences, Inc. Modulators of acetylcholine receptors
US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
US6369068B1 (en) 1995-06-07 2002-04-09 Smithkline Beecham Corporation Amino substituted pyrimidine containing compounds
IL118544A (en) 1995-06-07 2001-08-08 Smithkline Beecham Corp History of imidazole, the process for their preparation and the pharmaceutical preparations containing them
ZA9610687B (en) * 1995-12-22 1997-09-29 Smithkline Beecham Corp Novel synthesis.
US6046208A (en) * 1996-01-11 2000-04-04 Smithkline Beecham Corporation Substituted imidazole compounds
AU715900B2 (en) * 1996-01-11 2000-02-10 Smithkline Beecham Corporation Novel substituted imidazole compounds
AP9700912A0 (en) 1996-01-11 1997-01-31 Smithkline Beecham Corp Novel cycloalkyl substituted imidazoles
ZA97175B (en) * 1996-01-11 1997-11-04 Smithkline Beecham Corp Novel substituted imidazole compounds.
US6096739A (en) * 1996-03-25 2000-08-01 Smithkline Beecham Corporation Treatment for CNS injuries
WO1998007425A1 (en) 1996-08-21 1998-02-26 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
US5965583A (en) * 1997-04-24 1999-10-12 Ortho-Mcneil Pharmaceutical, Inc. Substituted imidazoles useful in the treatment of inflammatory disease
AU7966198A (en) 1997-06-13 1998-12-30 Smithkline Beecham Corporation Novel pyrazole and pyrazoline substituted compounds
US6610695B1 (en) 1997-06-19 2003-08-26 Smithkline Beecham Corporation Aryloxy substituted pyrimidine imidazole compounds
US6562832B1 (en) 1997-07-02 2003-05-13 Smithkline Beecham Corporation Substituted imidazole compounds
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
US6489325B1 (en) 1998-07-01 2002-12-03 Smithkline Beecham Corporation Substituted imidazole compounds
AU8381098A (en) 1997-07-02 1999-01-25 Smithkline Beecham Corporation Novel cycloalkyl substituted imidazoles
TW517055B (en) 1997-07-02 2003-01-11 Smithkline Beecham Corp Novel substituted imidazole compounds
EP1041989A4 (en) 1997-10-08 2002-11-20 Smithkline Beecham Corp NEW SUBSTITUTED CYCLOALCENYL COMPOUNDS
AR017219A1 (es) 1997-12-19 2001-08-22 Smithkline Beecham Corp Derivados de imidazol 1,4,5 sustituidos, composiciones que los comprenden, procedimiento para la preparacion de dichos derivados, uso de los derivados parala manufactura de un medicamento
JP2002516322A (ja) * 1998-05-22 2002-06-04 スミスクライン・ビーチャム・コーポレイション 新規２−アルキル置換イミダゾール化合物
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
EP1112070B1 (en) * 1998-08-20 2004-05-12 Smithkline Beecham Corporation Novel substituted triazole compounds
DE69914357T2 (de) 1998-11-04 2004-11-11 Smithkline Beecham Corp. Pyridin-4-yl oder pyrimidin-4-yl substituierte pyrazine
WO2000029399A1 (en) * 1998-11-12 2000-05-25 Boehringer Ingelheim (Canada) Ltd. Antiherpes compounds
US6239279B1 (en) 1998-12-16 2001-05-29 Smithkline Beecham Corporation Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
WO2001037835A1 (en) 1999-11-22 2001-05-31 Smithkline Beecham Plc. Novel compounds
AU1782301A (en) 1999-11-23 2001-06-04 Smithkline Beecham Corporation 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p39 kinase inhibitors
WO2001038312A1 (en) 1999-11-23 2001-05-31 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
ES2241675T3 (es) 1999-11-23 2005-11-01 Smithkline Beecham Corporation Compuestos de 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de cspb/p38 quinasa.
US6759410B1 (en) 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
DE60103136T2 (de) * 2000-03-06 2004-10-28 Smithkline Beecham Plc, Brentford Imidazolderivate als Raf-Kinase Inhibitoren
GB0005357D0 (en) 2000-03-06 2000-04-26 Smithkline Beecham Plc Compounds
EP1333833B1 (en) * 2000-10-23 2011-08-24 GlaxoSmithKline LLC Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compound for the treatment of CSBP/p38 kinase mediated diseases
GB0112348D0 (en) * 2001-05-19 2001-07-11 Smithkline Beecham Plc Compounds
WO2003022837A1 (en) * 2001-09-05 2003-03-20 Smithkline Beecham P.L.C. Heterocycle-carboxamide derivatives as raf kinase inhibitors
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox
CA2524889A1 (en) * 2003-05-08 2004-11-18 Astellas Pharma Inc. 1,2-diarylimidazoles useful as inhibitors of cox
CN101495475A (zh) * 2005-03-25 2009-07-29 葛兰素集团有限公司 制备吡啶并[2,3-d]嘧啶-7-酮和3,4-二氢嘧啶并[4,5-d]嘧啶-2(1H)-酮衍生物的方法
AR053346A1 (es) 2005-03-25 2007-05-02 Glaxo Group Ltd Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38
WO2013049272A2 (en) 2011-09-29 2013-04-04 Theraceutix, Llc Composition and method for treatment of symptoms associated with various skin conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558645A (en) * 1968-07-08 1971-01-26 Sandoz Ag 2-(4-(4',5-diphenyl - 2 - imidazolyl)-phenoxy) lower aliphatic monocarboxylic acids
CH561716A5 (ko) * 1971-05-10 1975-05-15 Ciba Geigy Ag
GB1469532A (en) * 1973-06-28 1977-04-06 Dumex Ltd As Imimdazolyl-alkanoic acid derivatives
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols

Also Published As

Publication number Publication date
PL236997A1 (en) 1983-01-03
NZ197828A (en) 1985-11-08
KR850002746A (ko) 1985-05-15
ES514583A0 (es) 1983-05-16
US4447431A (en) 1984-05-08
AU5655586A (en) 1986-09-11
KR850002753A (ko) 1985-05-15
KR850002748A (ko) 1985-05-15
SU1138023A3 (ru) 1985-01-30
ES8306124A1 (es) 1983-05-16
IE811680L (en) 1982-01-25
ES8306119A1 (es) 1983-05-16
IL63410A0 (en) 1981-10-30
GB2080805A (en) 1982-02-10
IE52071B1 (en) 1987-06-10
KR850001064B1 (ko) 1985-07-25
KR850000890B1 (ko) 1985-06-26
SU1145928A3 (ru) 1985-03-15
EP0045081A2 (de) 1982-02-03
KR850000889B1 (ko) 1985-06-26
PL237002A1 (en) 1983-02-28
JPS5756466A (en) 1982-04-05
KR850000911B1 (ko) 1985-06-27
KR850002754A (ko) 1985-05-15
ES8306123A1 (es) 1983-05-16
FI812326L (fi) 1982-01-26
SU1205763A3 (ru) 1986-01-15
PL237005A1 (en) 1983-02-28
DD201677A5 (de) 1983-08-03
ES514585A0 (es) 1983-07-01
KR830006230A (ko) 1983-09-20
AR230269A1 (es) 1984-03-01
SU1205764A3 (ru) 1986-01-15
PT73424B (en) 1983-06-20
CA1175431A (en) 1984-10-02
KR850002752A (ko) 1985-05-15
GB2080805B (en) 1984-03-07
EP0045081B1 (de) 1986-01-08
ES514579A0 (es) 1983-05-16
SU1235454A3 (ru) 1986-05-30
KR850000887B1 (ko) 1985-06-26
ATE17349T1 (de) 1986-01-15
KR850002745A (ko) 1985-05-15
PL237003A1 (en) 1983-02-28
KR850000888B1 (ko) 1985-06-26
SU1152520A3 (en) 1985-04-23
PL237004A1 (en) 1983-02-28
KR850000885B1 (ko) 1985-06-26
DK331881A (da) 1982-01-26
KR850002744A (ko) 1985-05-15
ES514581A0 (es) 1983-05-16
KR850000883B1 (ko) 1985-06-26
ES8301472A1 (es) 1982-12-01
KR850002756A (ko) 1985-05-15
GR75287B (ko) 1984-07-13
ES514580A0 (es) 1983-05-16
KR850002755A (ko) 1985-05-15
KR850002747A (ko) 1985-05-15
DD202554A5 (de) 1983-09-21
ES8306122A1 (es) 1983-05-16
EP0045081A3 (en) 1982-04-07
ES8307245A1 (es) 1983-07-01
ZA815078B (en) 1982-07-28
KR850000886B1 (ko) 1985-06-26
KR850000892B1 (ko) 1985-06-26
ES8306121A1 (es) 1983-05-16
PL135822B1 (en) 1985-12-31
ES514584A0 (es) 1983-05-16
PL232352A1 (ko) 1982-12-20
AU7340481A (en) 1982-01-28
SU1169534A3 (ru) 1985-07-23
IL63410A (en) 1986-04-29
DE3173434D1 (en) 1986-02-20
SU1227112A3 (ru) 1986-04-23
KR850002750A (ko) 1985-05-15
PT73424A (en) 1981-08-01
KR850000873B1 (ko) 1985-06-22
PL237001A1 (en) 1983-02-28
ES514582A0 (es) 1983-05-16
PL237000A1 (en) 1983-02-28
ES8306120A1 (es) 1983-05-16
KR850000884B1 (ko) 1985-06-26
ES504257A0 (es) 1982-12-01
KR850000891B1 (ko) 1985-06-26
NO812542L (no) 1982-01-26

Similar Documents

Publication Publication Date Title
KR850002744A (ko) 삼-치환 이미다졸 유도체의 제조방법
JPS5770886A (en) Imidazole derivative
ES505373A0 (es) Un metodo para preparar derivados de fenilpiperazina
IT1138678B (it) Metodo per fabbricare un pezzo cavo
KR850003303A (ko) 치환된 벤조일-우레아의 제조방법
DK370781A (da) Fremgangsmaade til fremstilling af 3,4-bis-phenyl-1,2,4-triazoler
KR850002010A (ko) 헤테로사이클릭 화합물의 제조방법
JPS5742688A (en) Substituted n-alkylimidazole derivative
KR850002012A (ko) 헤테로 사이클릭 유도체의 제조방법
DK188881A (da) Fremgangsmaade til fremstilling af 2-guanidinthiazol-derivater
DK369181A (da) Fremgangsmaade til fremstilling af triazolylvinylketonforbindelser
ES499135A0 (es) Un metodo de preparar tiosemicarbazonas sustituidas
ES505372A0 (es) Un metodo de preparar derivados de fenil-piperazina
KR860003647A (ko) 아릴-치환된 이미다졸 화합물의 제조방법
KR850003384A (ko) 9-카바모일플루오렌 유도체의 제조방법
KR850003301A (ko) 옥소옥세판 유도체의 합성방법
KR850002757A (ko) 사이클로 펜텐 유도체의 제조방법
KR850001460A (ko) 테트라졸 유도체의 제조방법
KR850000179A (ko) 세파피린 에스테르의 제조방법
JPS56169693A (en) Novel imidazole derivative
KR850003299A (ko) 티아졸린 유도체의 제조방법
NO811452L (no) Imidazolderivater.
BA97177B1 (bs) Psotupak za primjenu novih jedinjenja triazola i imidazola
KR860002947A (ko) α-술포닐옥시케톤 아세탈의 제조방법
ES503979A0 (es) Un procedimiento de preparacion de un derivado de la piridi-na

Legal Events

Date Code Title Description
A107 Divisional application of patent
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
NORF Unpaid initial registration fee