KR850002010A - 헤테로사이클릭 화합물의 제조방법 - Google Patents

헤테로사이클릭 화합물의 제조방법

Info

Publication number
KR850002010A
KR850002010A KR1019840004976A KR840004976A KR850002010A KR 850002010 A KR850002010 A KR 850002010A KR 1019840004976 A KR1019840004976 A KR 1019840004976A KR 840004976 A KR840004976 A KR 840004976A KR 850002010 A KR850002010 A KR 850002010A
Authority
KR
South Korea
Prior art keywords
heterocyclic compound
producing heterocyclic
producing
compound
heterocyclic
Prior art date
Application number
KR1019840004976A
Other languages
English (en)
Other versions
KR850000682B1 (ko
Inventor
왓트슨 크리디로 존
브래드 셔 존
윌슨 막파레인 막키논 존
부르스 주드 더칸
에드먼드 베이스 대비드
헤이스 로저
피어스 앤드류
Original Assignee
그랙소 그룹 리밋티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 그랙소 그룹 리밋티드 filed Critical 그랙소 그룹 리밋티드
Publication of KR850002010A publication Critical patent/KR850002010A/ko
Application granted granted Critical
Publication of KR850000682B1 publication Critical patent/KR850000682B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
KR1019840004976A 1980-02-28 1984-08-18 헤테로사이클릭 화합물의 제조방법 KR850000682B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8006806 1980-02-28
GB8006806 1980-02-28
KR1019810000669A KR850000668B1 (ko) 1980-02-28 1981-02-28 헤테로 사이클릭 화합물의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019810000669A Division KR850000668B1 (ko) 1980-02-28 1981-02-28 헤테로 사이클릭 화합물의 제조방법

Publications (2)

Publication Number Publication Date
KR850002010A true KR850002010A (ko) 1985-04-10
KR850000682B1 KR850000682B1 (ko) 1985-05-14

Family

ID=10511754

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1019810000669A KR850000668B1 (ko) 1980-02-28 1981-02-28 헤테로 사이클릭 화합물의 제조방법
KR1019840004976A KR850000682B1 (ko) 1980-02-28 1984-08-18 헤테로사이클릭 화합물의 제조방법
KR1019840004977A KR850000676B1 (ko) 1980-02-28 1984-08-20 헤테로사이클릭 화합물의 제조방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019810000669A KR850000668B1 (ko) 1980-02-28 1981-02-28 헤테로 사이클릭 화합물의 제조방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019840004977A KR850000676B1 (ko) 1980-02-28 1984-08-20 헤테로사이클릭 화합물의 제조방법

Country Status (26)

Country Link
US (1) US4670448A (ko)
JP (2) JPS56147777A (ko)
KR (3) KR850000668B1 (ko)
AT (2) AT380240B (ko)
AU (1) AU544357B2 (ko)
BE (1) BE887730A (ko)
CA (1) CA1158649A (ko)
CH (1) CH655104A5 (ko)
CY (1) CY1335A (ko)
DE (1) DE3107628A1 (ko)
DK (1) DK90681A (ko)
ES (4) ES499931A0 (ko)
FI (1) FI76076C (ko)
FR (1) FR2477150A1 (ko)
GB (1) GB2075007B (ko)
HK (1) HK69186A (ko)
IE (1) IE50987B1 (ko)
IL (1) IL62229A (ko)
IT (1) IT1209846B (ko)
KE (1) KE3629A (ko)
MY (1) MY8500428A (ko)
NL (2) NL186812C (ko)
NO (1) NO810681L (ko)
NZ (1) NZ196365A (ko)
SE (1) SE448233B (ko)
ZA (1) ZA811331B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57169452A (en) * 1981-04-14 1982-10-19 Teikoku Hormone Mfg Co Ltd Novel phenoxyalkylamide derivative
US4476126A (en) * 1981-06-11 1984-10-09 Glaxo Group Limited 1,2,4 Triazoze amines and their pharmaceutical use
ES8407030A1 (es) * 1982-02-24 1984-04-01 Glaxo Group Ltd Un procedimiento para prepararacion de derivados del triazol.
CA1189508A (en) * 1982-02-25 1985-06-25 Roger Hayes Heterocyclic derivatives as histamine h.sub.2- antagonists
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
GB8628475D0 (en) * 1986-11-28 1987-01-07 Glaxo Group Ltd Medicaments
GB8805268D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JP3328082B2 (ja) * 1994-12-13 2002-09-24 日本カーバイド工業株式会社 Ｎ−グアニジノチオ尿素塩及び３−アミノ−５−メルカプト−１，２，４−トリアゾールの製造方法
EP1223932A4 (en) 1999-10-01 2003-01-15 Smithkline Beecham Corp COMPOUNDS AND METHODS
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム １−置換―１―アミノグアニジン又はその塩、及びこれらの製造方法
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
DE3067920D1 (en) * 1979-03-02 1984-06-28 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
KR850000676B1 (ko) 1985-05-10
IE50987B1 (en) 1986-09-03
AU6793381A (en) 1981-09-03
KR850000682B1 (ko) 1985-05-14
ES8304954A1 (es) 1983-03-16
FI810619L (fi) 1981-08-29
KE3629A (en) 1986-05-16
NZ196365A (en) 1984-07-31
AT387774B (de) 1989-03-10
SE448233B (sv) 1987-02-02
DE3107628A1 (de) 1982-04-01
ES509669A0 (es) 1983-03-16
ES530741A0 (es) 1985-07-01
ES8506292A1 (es) 1985-07-01
GB2075007A (en) 1981-11-11
KR830005164A (ko) 1983-08-03
AU544357B2 (en) 1985-05-23
FR2477150A1 (fr) 1981-09-04
CH655104A5 (fr) 1986-03-27
FI76076B (fi) 1988-05-31
HK69186A (en) 1986-09-26
NL186812B (nl) 1990-10-01
IL62229A0 (en) 1981-03-31
ATA151084A (de) 1988-08-15
KR850002011A (ko) 1985-04-10
DK90681A (da) 1981-08-29
MY8500428A (en) 1985-12-31
FI76076C (fi) 1988-09-09
SE8101311L (sv) 1981-08-29
ES8205208A1 (es) 1982-06-01
ES8405775A1 (es) 1984-06-16
JPS6452763A (en) 1989-02-28
FR2477150B1 (ko) 1984-03-16
GB2075007B (en) 1983-07-13
ZA811331B (en) 1982-10-27
KR850000668B1 (ko) 1985-05-09
NL8802221A (nl) 1989-01-02
ES518305A0 (es) 1984-06-16
NO810681L (no) 1981-08-31
IE810431L (en) 1981-08-28
IT1209846B (it) 1989-08-30
US4670448A (en) 1987-06-02
CA1158649A (en) 1983-12-13
ES499931A0 (es) 1982-06-01
IL62229A (en) 1987-10-30
AT380240B (de) 1986-04-25
IT8147905A0 (it) 1981-02-27
CY1335A (en) 1986-10-24
NL186812C (nl) 1991-03-01
JPS56147777A (en) 1981-11-16
DE3107628C2 (ko) 1991-03-14
NL8100979A (nl) 1981-10-01
BE887730A (fr) 1981-08-27
JPH0338269B2 (ko) 1991-06-10
ATA93981A (de) 1985-09-15

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Legal Events

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A107 Divisional application of patent
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GRNT Written decision to grant
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Payment date: 19900508

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