AT387774B - Verfahren zur herstellung von neuen 1,2,4-triazol-derivaten - Google Patents

Verfahren zur herstellung von neuen 1,2,4-triazol-derivaten

Info

Publication number
AT387774B
AT387774B AT0151084A AT151084A AT387774B AT 387774 B AT387774 B AT 387774B AT 0151084 A AT0151084 A AT 0151084A AT 151084 A AT151084 A AT 151084A AT 387774 B AT387774 B AT 387774B
Authority
AT
Austria
Prior art keywords
triazole derivatives
producing new
producing
new
triazole
Prior art date
Application number
AT0151084A
Other languages
English (en)
Other versions
ATA151084A (de
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ATA151084A publication Critical patent/ATA151084A/de
Application granted granted Critical
Publication of AT387774B publication Critical patent/AT387774B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
AT0151084A 1980-02-28 1984-05-08 Verfahren zur herstellung von neuen 1,2,4-triazol-derivaten AT387774B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8006806 1980-02-28

Publications (2)

Publication Number Publication Date
ATA151084A ATA151084A (de) 1988-08-15
AT387774B true AT387774B (de) 1989-03-10

Family

ID=10511754

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0093981A AT380240B (de) 1980-02-28 1981-02-27 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT0151084A AT387774B (de) 1980-02-28 1984-05-08 Verfahren zur herstellung von neuen 1,2,4-triazol-derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0093981A AT380240B (de) 1980-02-28 1981-02-27 Verfahren zur herstellung von neuen heterocyclischen verbindungen

Country Status (26)

Country Link
US (1) US4670448A (de)
JP (2) JPS56147777A (de)
KR (3) KR850000668B1 (de)
AT (2) AT380240B (de)
AU (1) AU544357B2 (de)
BE (1) BE887730A (de)
CA (1) CA1158649A (de)
CH (1) CH655104A5 (de)
CY (1) CY1335A (de)
DE (1) DE3107628A1 (de)
DK (1) DK90681A (de)
ES (4) ES499931A0 (de)
FI (1) FI76076C (de)
FR (1) FR2477150A1 (de)
GB (1) GB2075007B (de)
HK (1) HK69186A (de)
IE (1) IE50987B1 (de)
IL (1) IL62229A (de)
IT (1) IT1209846B (de)
KE (1) KE3629A (de)
MY (1) MY8500428A (de)
NL (2) NL186812C (de)
NO (1) NO810681L (de)
NZ (1) NZ196365A (de)
SE (1) SE448233B (de)
ZA (1) ZA811331B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57169452A (en) * 1981-04-14 1982-10-19 Teikoku Hormone Mfg Co Ltd Novel phenoxyalkylamide derivative
AU8480982A (en) * 1981-06-11 1983-01-13 Glaxo Group Limited 1,2,4-triazole derivatives with histamine h2-blocking activity
PT76280A (en) * 1982-02-24 1983-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives
CA1189508A (en) * 1982-02-25 1985-06-25 Roger Hayes Heterocyclic derivatives as histamine h.sub.2- antagonists
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
GB8628475D0 (en) * 1986-11-28 1987-01-07 Glaxo Group Ltd Medicaments
GB8805268D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JP3328082B2 (ja) * 1994-12-13 2002-09-24 日本カーバイド工業株式会社 N−グアニジノチオ尿素塩及び3−アミノ−5−メルカプト−1,2,4−トリアゾールの製造方法
WO2001024796A1 (en) * 1999-10-01 2001-04-12 Smithkline Beecham Corporation 1,2,4-triazole derivatives, composition, process of making and methods of use
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム 1−置換―1―アミノグアニジン又はその塩、及びこれらの製造方法
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
DK89480A (da) * 1979-03-02 1980-09-03 Glaxo Group Ltd R fremgangsmaade til fremstilling af heterocycliske forbindelse

Also Published As

Publication number Publication date
DE3107628C2 (de) 1991-03-14
FR2477150B1 (de) 1984-03-16
IE50987B1 (en) 1986-09-03
ES8304954A1 (es) 1983-03-16
NZ196365A (en) 1984-07-31
IE810431L (en) 1981-08-28
KR850002010A (ko) 1985-04-10
ES518305A0 (es) 1984-06-16
DK90681A (da) 1981-08-29
HK69186A (en) 1986-09-26
KR830005164A (ko) 1983-08-03
MY8500428A (en) 1985-12-31
ES8205208A1 (es) 1982-06-01
ES8405775A1 (es) 1984-06-16
IL62229A0 (en) 1981-03-31
ATA93981A (de) 1985-09-15
GB2075007B (en) 1983-07-13
KR850000682B1 (ko) 1985-05-14
FI76076C (fi) 1988-09-09
IL62229A (en) 1987-10-30
JPH0338269B2 (de) 1991-06-10
AU544357B2 (en) 1985-05-23
KR850000676B1 (ko) 1985-05-10
NO810681L (no) 1981-08-31
ATA151084A (de) 1988-08-15
KR850002011A (ko) 1985-04-10
FI76076B (fi) 1988-05-31
SE8101311L (sv) 1981-08-29
IT1209846B (it) 1989-08-30
FI810619L (fi) 1981-08-29
GB2075007A (en) 1981-11-11
ES509669A0 (es) 1983-03-16
JPS6452763A (en) 1989-02-28
KR850000668B1 (ko) 1985-05-09
NL8802221A (nl) 1989-01-02
SE448233B (sv) 1987-02-02
CA1158649A (en) 1983-12-13
DE3107628A1 (de) 1982-04-01
NL186812B (nl) 1990-10-01
FR2477150A1 (fr) 1981-09-04
KE3629A (en) 1986-05-16
ES530741A0 (es) 1985-07-01
IT8147905A0 (it) 1981-02-27
BE887730A (fr) 1981-08-27
CH655104A5 (fr) 1986-03-27
JPS56147777A (en) 1981-11-16
NL186812C (nl) 1991-03-01
CY1335A (en) 1986-10-24
US4670448A (en) 1987-06-02
ZA811331B (en) 1982-10-27
NL8100979A (nl) 1981-10-01
AU6793381A (en) 1981-09-03
ES499931A0 (es) 1982-06-01
AT380240B (de) 1986-04-25
ES8506292A1 (es) 1985-07-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties