JPS57169452A - Novel phenoxyalkylamide derivative - Google Patents
Novel phenoxyalkylamide derivativeInfo
- Publication number
- JPS57169452A JPS57169452A JP56055129A JP5512981A JPS57169452A JP S57169452 A JPS57169452 A JP S57169452A JP 56055129 A JP56055129 A JP 56055129A JP 5512981 A JP5512981 A JP 5512981A JP S57169452 A JPS57169452 A JP S57169452A
- Authority
- JP
- Japan
- Prior art keywords
- expressed
- formula
- group
- formulai
- linked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A phenoxyalkylamide expressed by formulaI(R1 and R2 are lower alkyl or may form a 4-W8-membered heterocyclic ring containing nitrogen together with N to which they are linked which may have a substituent group, e.g. OH; R3 is H or lower alkyl; R4 is H or 1W12C hydrocarbon, etc. which may have a substituent group; n is an integer 2W6; the group expressed by formula VI is linked to the m- or p-position to the aminoalkyl group) and a salt thereof.
EXAMPLE: 2'-Methyl-4-(3-dimethylaminomethylphenoxy)butanoic acid hydrazide.
USE: An antiulcer agent having improved inhibitory action on the gastric acid secretion due to the histaminic H2 receptor antagonistic action.
PROCESS: A phenolic derivative expressed by formula II is reacted with a carboxylic ester expressed by formula III (A is halogen, etc.) to give a compound expressed by formula IV, which is then amidated with an amine expressed by formula V to afford the aimed compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56055129A JPS57169452A (en) | 1981-04-14 | 1981-04-14 | Novel phenoxyalkylamide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56055129A JPS57169452A (en) | 1981-04-14 | 1981-04-14 | Novel phenoxyalkylamide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57169452A true JPS57169452A (en) | 1982-10-19 |
JPH0141615B2 JPH0141615B2 (en) | 1989-09-06 |
Family
ID=12990153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56055129A Granted JPS57169452A (en) | 1981-04-14 | 1981-04-14 | Novel phenoxyalkylamide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57169452A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100479019B1 (en) * | 1998-05-22 | 2005-08-29 | 씨제이 주식회사 | Catethcol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55100368A (en) * | 1979-01-19 | 1980-07-31 | Pfizer | Nnbenzylimidazole and its manufacture and use |
JPS55120571A (en) * | 1979-03-02 | 1980-09-17 | Glaxo Group Ltd | Heterocyclic derivative |
JPS56139483A (en) * | 1980-03-08 | 1981-10-30 | Pfizer | Imidazole derivatives, manufacture and thromboxane synthetic enzyme action inhibitor made therefrom |
JPS56147777A (en) * | 1980-02-28 | 1981-11-16 | Glaxo Group Ltd | Novel heterocyclic derivative, its manufacture and medicine containing it |
-
1981
- 1981-04-14 JP JP56055129A patent/JPS57169452A/en active Granted
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55100368A (en) * | 1979-01-19 | 1980-07-31 | Pfizer | Nnbenzylimidazole and its manufacture and use |
JPS55120571A (en) * | 1979-03-02 | 1980-09-17 | Glaxo Group Ltd | Heterocyclic derivative |
JPS56147777A (en) * | 1980-02-28 | 1981-11-16 | Glaxo Group Ltd | Novel heterocyclic derivative, its manufacture and medicine containing it |
JPS56139483A (en) * | 1980-03-08 | 1981-10-30 | Pfizer | Imidazole derivatives, manufacture and thromboxane synthetic enzyme action inhibitor made therefrom |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100479019B1 (en) * | 1998-05-22 | 2005-08-29 | 씨제이 주식회사 | Catethcol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Also Published As
Publication number | Publication date |
---|---|
JPH0141615B2 (en) | 1989-09-06 |
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