ES8405775A1 - Un procedimiento para la preparacion de derivados de triazol. - Google Patents
Un procedimiento para la preparacion de derivados de triazol.Info
- Publication number
- ES8405775A1 ES8405775A1 ES518305A ES518305A ES8405775A1 ES 8405775 A1 ES8405775 A1 ES 8405775A1 ES 518305 A ES518305 A ES 518305A ES 518305 A ES518305 A ES 518305A ES 8405775 A1 ES8405775 A1 ES 8405775A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- amine compounds
- triazole amine
- triazole
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE TRIAZOL, DE FORMULA GENERAL (I), EN LA QUE R1 REPRESENTA HIDROGENO, ALQUENILO O ALQUINILO; R2 REPRESENTA HIDROGENO O ALQUILO C1-4; ALQ REPRESENTA UNA CADENA ALQUILENICA LINEAL O RAMIFICADA; Q REPRESENTA UN ANILLO DE FURANO O DE TIOFENO; X REPRESENTA OXIGENO, AZUFRE O METILENO; N REPRESENTA 0, 1, 2 O 3; M ES UN NUMERO ENTERO COMPRENDIDO ENTRE 2 Y 5; R3 REPRESENTA HIDROGENO, ALQUILO O ALQUENILO; R4 REPRESENTA UN RADICAL; E Y REPRESENTA OXIGENO, AZUFRE O METILENO.CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA (II),EN LA QUE POR LO MENOS UNO DE LOS RADICALES DA, DB O DC REPRESENTA UN GRUPO REDUCIBLE, CON UN AGENTE REDUCTOR SELECCIONADO ENTRE UN HIDRURO METALICO E HIDROGENO/CATALIZADOR METALICO, EN PRESENCIA DE UN DISOLVENTE ORGANICO.DE APLICACION EN EL TRATAMIENTO DE LA ACIDEZ GASTRICA, ESPECIALMENTE EN LAS ULCERACIONES GASTRICAS Y PEPTICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8006806 | 1980-02-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES518305A0 ES518305A0 (es) | 1984-06-16 |
ES8405775A1 true ES8405775A1 (es) | 1984-06-16 |
Family
ID=10511754
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES499931A Expired ES8205208A1 (es) | 1980-02-28 | 1981-02-27 | Un procedimiento para la preparacion de derivados de triazol. |
ES509669A Granted ES509669A0 (es) | 1980-02-28 | 1982-02-16 | Un procedimiento para la preparacion de derivados de triazol. |
ES518305A Expired ES8405775A1 (es) | 1980-02-28 | 1982-12-16 | Un procedimiento para la preparacion de derivados de triazol. |
ES530741A Expired ES8506292A1 (es) | 1980-02-28 | 1984-03-16 | Un procedimiento para la preparacion de derivados de triazol |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES499931A Expired ES8205208A1 (es) | 1980-02-28 | 1981-02-27 | Un procedimiento para la preparacion de derivados de triazol. |
ES509669A Granted ES509669A0 (es) | 1980-02-28 | 1982-02-16 | Un procedimiento para la preparacion de derivados de triazol. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES530741A Expired ES8506292A1 (es) | 1980-02-28 | 1984-03-16 | Un procedimiento para la preparacion de derivados de triazol |
Country Status (26)
Country | Link |
---|---|
US (1) | US4670448A (es) |
JP (2) | JPS56147777A (es) |
KR (3) | KR850000668B1 (es) |
AT (2) | AT380240B (es) |
AU (1) | AU544357B2 (es) |
BE (1) | BE887730A (es) |
CA (1) | CA1158649A (es) |
CH (1) | CH655104A5 (es) |
CY (1) | CY1335A (es) |
DE (1) | DE3107628A1 (es) |
DK (1) | DK90681A (es) |
ES (4) | ES8205208A1 (es) |
FI (1) | FI76076C (es) |
FR (1) | FR2477150A1 (es) |
GB (1) | GB2075007B (es) |
HK (1) | HK69186A (es) |
IE (1) | IE50987B1 (es) |
IL (1) | IL62229A (es) |
IT (1) | IT1209846B (es) |
KE (1) | KE3629A (es) |
MY (1) | MY8500428A (es) |
NL (2) | NL186812C (es) |
NO (1) | NO810681L (es) |
NZ (1) | NZ196365A (es) |
SE (1) | SE448233B (es) |
ZA (1) | ZA811331B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57169452A (en) * | 1981-04-14 | 1982-10-19 | Teikoku Hormone Mfg Co Ltd | Novel phenoxyalkylamide derivative |
EP0070097A1 (en) * | 1981-06-11 | 1983-01-19 | Glaxo Group Limited | 1,2,4-Triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
ES520031A0 (es) * | 1982-02-24 | 1984-04-01 | Glaxo Group Ltd | Un procedimiento para prepararacion de derivados del triazol. |
CA1189508A (en) * | 1982-02-25 | 1985-06-25 | Roger Hayes | Heterocyclic derivatives as histamine h.sub.2- antagonists |
GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
GB8628475D0 (en) * | 1986-11-28 | 1987-01-07 | Glaxo Group Ltd | Medicaments |
GB8805268D0 (en) * | 1988-03-04 | 1988-04-07 | Glaxo Group Ltd | Medicaments |
JP3328082B2 (ja) * | 1994-12-13 | 2002-09-24 | 日本カーバイド工業株式会社 | N−グアニジノチオ尿素塩及び3−アミノ−5−メルカプト−1,2,4−トリアゾールの製造方法 |
EP1223932A4 (en) * | 1999-10-01 | 2003-01-15 | Smithkline Beecham Corp | COMPOUNDS AND METHODS |
JP4564786B2 (ja) * | 2004-06-07 | 2010-10-20 | 株式会社日本ファインケム | 1−置換―1―アミノグアニジン又はその塩、及びこれらの製造方法 |
EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
AR228941A1 (es) * | 1978-04-26 | 1983-05-13 | Glaxo Group Ltd | Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos |
GB2023133B (en) * | 1978-04-26 | 1982-09-08 | Glaxo Group Ltd | Heterocyclic derivatives |
NO800583L (no) * | 1979-03-02 | 1980-09-03 | Glaxo Group Ltd | Fremgangsmaate for fremstilling av farmakologisk aktive triazolderivater |
-
1981
- 1981-02-26 CH CH1288/81A patent/CH655104A5/fr not_active IP Right Cessation
- 1981-02-26 FR FR8103847A patent/FR2477150A1/fr active Granted
- 1981-02-27 NZ NZ196365A patent/NZ196365A/en unknown
- 1981-02-27 NO NO810681A patent/NO810681L/no unknown
- 1981-02-27 SE SE8101311A patent/SE448233B/sv not_active IP Right Cessation
- 1981-02-27 BE BE0/203963A patent/BE887730A/fr unknown
- 1981-02-27 IE IE431/81A patent/IE50987B1/en unknown
- 1981-02-27 DE DE19813107628 patent/DE3107628A1/de active Granted
- 1981-02-27 GB GB8106314A patent/GB2075007B/en not_active Expired
- 1981-02-27 CA CA000371889A patent/CA1158649A/en not_active Expired
- 1981-02-27 ES ES499931A patent/ES8205208A1/es not_active Expired
- 1981-02-27 IL IL62229A patent/IL62229A/xx unknown
- 1981-02-27 AT AT0093981A patent/AT380240B/de not_active IP Right Cessation
- 1981-02-27 DK DK90681A patent/DK90681A/da not_active Application Discontinuation
- 1981-02-27 FI FI810619A patent/FI76076C/fi not_active IP Right Cessation
- 1981-02-27 NL NLAANVRAGE8100979,A patent/NL186812C/xx not_active IP Right Cessation
- 1981-02-27 IT IT8147905A patent/IT1209846B/it active
- 1981-02-27 AU AU67933/81A patent/AU544357B2/en not_active Ceased
- 1981-02-27 ZA ZA00811331A patent/ZA811331B/xx unknown
- 1981-02-27 CY CY133581A patent/CY1335A/xx unknown
- 1981-02-28 JP JP2929381A patent/JPS56147777A/ja active Granted
- 1981-02-28 KR KR1019810000669A patent/KR850000668B1/ko active
-
1982
- 1982-02-16 ES ES509669A patent/ES509669A0/es active Granted
- 1982-12-16 ES ES518305A patent/ES8405775A1/es not_active Expired
-
1983
- 1983-02-10 US US06/465,616 patent/US4670448A/en not_active Expired - Fee Related
-
1984
- 1984-03-16 ES ES530741A patent/ES8506292A1/es not_active Expired
- 1984-05-08 AT AT0151084A patent/AT387774B/de not_active IP Right Cessation
- 1984-08-18 KR KR1019840004976A patent/KR850000682B1/ko not_active IP Right Cessation
- 1984-08-20 KR KR1019840004977A patent/KR850000676B1/ko not_active IP Right Cessation
-
1985
- 1985-12-30 MY MY428/85A patent/MY8500428A/xx unknown
-
1986
- 1986-04-16 KE KE3629A patent/KE3629A/xx unknown
- 1986-09-18 HK HK691/86A patent/HK69186A/xx unknown
-
1988
- 1988-02-29 JP JP63047352A patent/JPS6452763A/ja active Pending
- 1988-09-09 NL NL8802221A patent/NL8802221A/nl not_active Application Discontinuation
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