ES486041A1 - Procedimiento para la obtencion de la forma a diastereomera del 1-(4-clorofenoxi)-1-(1-imidazolil)-3,3-dimetil-2-butanol - Google Patents

Procedimiento para la obtencion de la forma a diastereomera del 1-(4-clorofenoxi)-1-(1-imidazolil)-3,3-dimetil-2-butanol

Info

Publication number
ES486041A1
ES486041A1 ES486041A ES486041A ES486041A1 ES 486041 A1 ES486041 A1 ES 486041A1 ES 486041 A ES486041 A ES 486041A ES 486041 A ES486041 A ES 486041A ES 486041 A1 ES486041 A1 ES 486041A1
Authority
ES
Spain
Prior art keywords
chlorophenoxy
imidazolyl
butanol
dimethyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486041A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES486041A1 publication Critical patent/ES486041A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la obtención de la forma A diastereomera del 1-(4-clorofenoxi)-1-(1- imidazolil)-3,3-dimetil(2(butanol, de fórmula I, **(fórmula)** . En la realización de la reacción según la presente invención se emplean por 1 mol de la cetona de fórmula (II) preferentemente 0,35 hasta 1,5 moles de alcoholato secundario. Para el aislamiento del compuesto de fórmula (I) se retira el disolvente en exceso por destilación en vacío y el compuesto de aluminio formado se descompone con ácido sulfúrico o bien solución de hidrógenosulfato sódico. La ulterior elaboración se efectúa en la forma usual.
ES486041A 1978-11-18 1979-11-16 Procedimiento para la obtencion de la forma a diastereomera del 1-(4-clorofenoxi)-1-(1-imidazolil)-3,3-dimetil-2-butanol Expired ES486041A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782850057 DE2850057A1 (de) 1978-11-18 1978-11-18 Diastereomeres 1-(4-chlorphenoxy)- 1-(1-imidazolyl)-3,3-dimethyl-2-butanol, verfahren zu seiner herstellung sowie seine verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES486041A1 true ES486041A1 (es) 1980-05-16

Family

ID=6054996

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486041A Expired ES486041A1 (es) 1978-11-18 1979-11-16 Procedimiento para la obtencion de la forma a diastereomera del 1-(4-clorofenoxi)-1-(1-imidazolil)-3,3-dimetil-2-butanol

Country Status (15)

Country Link
US (1) US4418072A (es)
EP (1) EP0011191A1 (es)
JP (1) JPS5572172A (es)
AU (1) AU5317079A (es)
CA (1) CA1124246A (es)
DD (1) DD146949A5 (es)
DE (1) DE2850057A1 (es)
DK (1) DK488479A (es)
ES (1) ES486041A1 (es)
FI (1) FI793587A (es)
HU (1) HU179119B (es)
IL (1) IL58733A (es)
NO (1) NO793574L (es)
NZ (1) NZ192129A (es)
ZA (1) ZA796181B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3035022A1 (de) * 1980-09-17 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung und reinigung von phenoxyazolyl-butanon-derivaten
DE3100261A1 (de) * 1981-01-08 1982-08-05 Basf Ag, 6700 Ludwigshafen Keten-o,n-acetale, verfahren zu ihrer herstellung, diese enthaltende fungizide und ihre verwendung zur bekaempfung von pilzen
DE3228867A1 (de) * 1982-08-03 1984-02-16 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-olen
DE3321023A1 (de) * 1983-06-10 1984-12-13 Basf Ag, 6700 Ludwigshafen Triazolylalkohole, verfahren zu ihrer herstellung und ihre verwendung als fungizide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2333354C2 (de) * 1973-06-30 1983-12-15 Bayer Ag, 5090 Leverkusen 2-Aryloxy-2-(imidazol-1-yl)-äthanole sowie deren Salze, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
DE2333355C2 (de) * 1973-06-30 1984-01-19 Bayer Ag, 5090 Leverkusen Antimikrobielle Mittel

Also Published As

Publication number Publication date
DK488479A (da) 1980-05-19
NO793574L (no) 1980-05-20
ZA796181B (en) 1980-12-31
IL58733A0 (en) 1980-02-29
US4418072A (en) 1983-11-29
FI793587A (fi) 1980-05-19
DD146949A5 (de) 1981-03-11
JPS5572172A (en) 1980-05-30
HU179119B (en) 1982-08-28
EP0011191A1 (de) 1980-05-28
IL58733A (en) 1983-11-30
AU5317079A (en) 1980-05-22
NZ192129A (en) 1981-04-24
DE2850057A1 (de) 1980-05-29
CA1124246A (en) 1982-05-25

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