ES486279A1 - Procedimiento para la obtencion de hidroxipropil-triazoles - Google Patents

Procedimiento para la obtencion de hidroxipropil-triazoles

Info

Publication number
ES486279A1
ES486279A1 ES486279A ES486279A ES486279A1 ES 486279 A1 ES486279 A1 ES 486279A1 ES 486279 A ES486279 A ES 486279A ES 486279 A ES486279 A ES 486279A ES 486279 A1 ES486279 A1 ES 486279A1
Authority
ES
Spain
Prior art keywords
hydroxypropyl
triazoles
preparation
compounds
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486279A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES486279A1 publication Critical patent/ES486279A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Abstract

Procedimiento para la obtención de hidroxipropil-triazoles, de fórmula **(fórmula)** donde Az significa triazol, R significa fenilo, naftilo, o tetrahidronaftilo, en caso dado sustituidos, R{sup,1} significa fenilo, en caso dado sustituido, o cicloalquilo y R{sup,2} significa hidrógeno o R{sup,1} y R{sup,2} juntos en la posición o entre sí significan un puente metileno de varios miembros, en caso dado sustituido, o junto con el anillo fenilo significa naftilo, R{sup,3} significa halógeno, alquilo, alcoxi o halogenoalquilo y n está por 0, 1, 2 ó 3, y sus sales de adición de ácido fisiológicamente compatibles.
ES486279A 1978-11-25 1979-11-23 Procedimiento para la obtencion de hidroxipropil-triazoles Expired ES486279A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782851086 DE2851086A1 (de) 1978-11-25 1978-11-25 Hydroxypropyl-triazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES486279A1 true ES486279A1 (es) 1980-05-16

Family

ID=6055560

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486279A Expired ES486279A1 (es) 1978-11-25 1979-11-23 Procedimiento para la obtencion de hidroxipropil-triazoles

Country Status (18)

Country Link
US (1) US4381306A (es)
EP (1) EP0011768B1 (es)
JP (1) JPS55108860A (es)
AT (1) ATE324T1 (es)
AU (1) AU536920B2 (es)
CA (1) CA1130296A (es)
DD (1) DD146824A5 (es)
DE (2) DE2851086A1 (es)
DK (1) DK152493C (es)
ES (1) ES486279A1 (es)
FI (1) FI65992C (es)
HU (1) HU179414B (es)
IE (1) IE48880B1 (es)
IL (1) IL58782A (es)
NO (1) NO793673L (es)
NZ (1) NZ192195A (es)
PH (1) PH16119A (es)
ZA (1) ZA796356B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551469A (en) * 1979-03-07 1985-11-05 Imperial Chemical Industries Plc Antifungal triazole ethanol derivatives
US4654332A (en) * 1979-03-07 1987-03-31 Imperial Chemical Industries Plc Heterocyclic compounds
US4927839A (en) * 1979-03-07 1990-05-22 Imperial Chemical Industries Plc Method of preventing fungal attack on wood, hides, leather or paint films using a triazole
DE3018865A1 (de) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen Antimikrobielle mittel
AU542623B2 (en) * 1980-05-16 1985-02-28 Bayer Aktiengesellschaft 1-hydroxyethyl-azole derivatives
DE3177292T2 (de) * 1980-08-18 1993-03-11 Ici Plc Triazol-verbindungen, verfahren zu ihrer herstellung und ihre verwendung als fungizide und pflanzenwachstumsregulatoren.
EP0046337A3 (en) * 1980-08-20 1982-09-15 Imperial Chemical Industries Plc Triazole compounds, a process for preparing them, their use as plant and pharmaceutical fungicides and as plant growth regulators and compositions containing them
NZ198084A (en) * 1980-08-28 1984-12-14 Ici Ltd Pharmaceutical and veterinary fungicidal compositions containing certain 1,1-disubstituted-2-(1,2,4-triazol-1-yl)ethanol derivatives
AT375359B (de) * 1980-09-02 1984-07-25 Ici Plc Verfahren zur herstellung von neuen verbindungen
AU8314482A (en) * 1981-05-19 1982-11-25 Imperial Chemical Industries Plc 3-triazolyl(imidazolyl)-2,2 bis phenyl-propionamides
DE3232647A1 (de) * 1982-09-02 1984-03-08 Bayer Ag, 5090 Leverkusen Substituierte tert.-butanol-derivate, verfahren zu ihrer herstellung und diese enthaltende antimykotische mittel
DE3245504A1 (de) * 1982-12-09 1984-06-14 Bayer Ag, 5090 Leverkusen Fungizide mittel, deren herstellung und verwendung
DE3461637D1 (en) * 1983-02-16 1987-01-22 Pfizer Ltd Triazole antifungal agents
ATE72119T1 (de) * 1987-11-09 1992-02-15 Bayer Ag Antimycotische zusammensetzungen aus nikkomycin- verbindungen und antimycotischem azol.
US5096889A (en) * 1987-11-09 1992-03-17 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US5006513A (en) * 1987-11-09 1991-04-09 Miles Inc. Antimycotic compositions of nikkomycin compounds and azole antimycotica
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
WO1989005801A1 (en) * 1987-12-17 1989-06-29 E.I. Du Pont De Nemours And Company Antifungal carbinols
US4914087A (en) * 1988-02-29 1990-04-03 Bayer Ag Nikkomycin derivatives, antimycotic compositions of nikkomycin derivatives and azole antimycotics
US5098920A (en) * 1990-05-04 1992-03-24 G. D. Searle & Co. 1h-substituted-1,2,4-triazole compounds and methods of use thereof for treatment of cardiovascular disorders
US5155117A (en) * 1991-04-12 1992-10-13 G. D. Searle & Co. 1-arylheteroarylalkyl substituted-1h-1,2,4-triazole compounds for treatment of circulatory disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002763A (en) * 1972-09-26 1977-01-11 Bayer Aktiengesellschaft 1,2,4-Triazole antimycotic compositions and use thereof
DE2324424A1 (de) * 1973-05-15 1974-12-05 Bayer Ag Antimikrobielle mittel
DE2431407C2 (de) * 1974-06-29 1982-12-02 Bayer Ag, 5090 Leverkusen 1,2,4-Triazol-1-yl-alkanone und -alkanole, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide
GB1569267A (en) * 1975-12-16 1980-06-11 Ici Ltd Substituted propiophenones and herbicidal and fungicidal compositions containing them
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2705679A1 (de) * 1977-02-11 1978-08-17 Bayer Ag Antimikrobielle mittel

Also Published As

Publication number Publication date
AU5317279A (en) 1980-05-29
DK152493B (da) 1988-03-07
JPS6258355B2 (es) 1987-12-05
ZA796356B (en) 1980-12-31
AU536920B2 (en) 1984-05-31
DK499679A (da) 1980-05-26
HU179414B (en) 1982-10-28
FI65992C (fi) 1984-08-10
DE2961083D1 (en) 1981-12-24
IL58782A (en) 1984-02-29
JPS55108860A (en) 1980-08-21
IE792241L (en) 1980-05-25
EP0011768A1 (de) 1980-06-11
PH16119A (en) 1983-06-30
NO793673L (no) 1980-05-28
NZ192195A (en) 1981-10-19
EP0011768B1 (de) 1981-10-21
IE48880B1 (en) 1985-06-12
US4381306A (en) 1983-04-26
CA1130296A (en) 1982-08-24
FI793688A (fi) 1980-05-26
DK152493C (da) 1988-07-25
ATE324T1 (de) 1981-11-15
FI65992B (fi) 1984-04-30
DE2851086A1 (de) 1980-06-04
IL58782A0 (en) 1980-02-29
DD146824A5 (de) 1981-03-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601