ES486278A1 - Procedimiento para la obtencion de fluorenil-azolilmetil- carbinoles - Google Patents

Procedimiento para la obtencion de fluorenil-azolilmetil- carbinoles

Info

Publication number
ES486278A1
ES486278A1 ES486278A ES486278A ES486278A1 ES 486278 A1 ES486278 A1 ES 486278A1 ES 486278 A ES486278 A ES 486278A ES 486278 A ES486278 A ES 486278A ES 486278 A1 ES486278 A1 ES 486278A1
Authority
ES
Spain
Prior art keywords
medicaments
carbinols
preparation
azolylmethyl
fluorenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486278A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES486278A1 publication Critical patent/ES486278A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para la obtención de fluorenil-azolilmetil-carbinoles de fórmula **(fórmula)** donde Az significa imidazol o triazol, R significa fenilo, bencilo, naftilo, naftilmetilo, tetrahidronaftilo o tetrahidronaftilmetilo, en caso dado sustituidos, R{sup,1} significa halógeno o alquilo y n representa 0, 1 ó 2.
ES486278A 1978-11-25 1979-11-23 Procedimiento para la obtencion de fluorenil-azolilmetil- carbinoles Expired ES486278A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782851143 DE2851143A1 (de) 1978-11-25 1978-11-25 Fluorenyl-azolylmethyl-carbinole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES486278A1 true ES486278A1 (es) 1980-05-16

Family

ID=6055604

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486278A Expired ES486278A1 (es) 1978-11-25 1979-11-23 Procedimiento para la obtencion de fluorenil-azolilmetil- carbinoles

Country Status (8)

Country Link
US (1) US4239765A (es)
EP (1) EP0011770B1 (es)
JP (1) JPS5573661A (es)
AT (1) ATE291T1 (es)
CA (1) CA1130810A (es)
DE (2) DE2851143A1 (es)
ES (1) ES486278A1 (es)
IL (1) IL58774A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3369131D1 (en) * 1982-04-22 1987-02-19 Ici Plc Antifungal azolyl phenyl substituted alicyclic alcohols
US4533670A (en) * 1983-09-21 1985-08-06 Eli Lilly And Company Anti-convulsant fluorenylalkylimidazole derivatives, compositions, and method of use
CA1249832A (en) * 1984-02-03 1989-02-07 Shionogi & Co., Ltd. Azolyl cycloalkanol derivatives and agricultural fungicides
US4859693A (en) * 1988-08-10 1989-08-22 E. I. Du Pont De Nemours And Company Antiinflammatory carbinoloimidazoles
US6037361A (en) * 1998-03-09 2000-03-14 Warner-Lambert Company Fluorinated butyric acids and their derivatives as inhibitors of matrix metalloproteinases
CN109503736A (zh) * 2017-09-15 2019-03-22 常州强力先端电子材料有限公司 芴类光引发剂及包含其的光固化组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1964996C3 (de) * 1969-12-24 1978-11-30 Bayer Ag, 5090 Leverkusen 9-Azolyl-fluoren-9-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Mittel zur Regulierung des Pflanzenwachstums
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Also Published As

Publication number Publication date
IL58774A (en) 1983-09-30
ATE291T1 (de) 1981-10-15
DE2961026D1 (en) 1981-12-24
IL58774A0 (en) 1980-02-29
CA1130810A (en) 1982-08-31
EP0011770A1 (de) 1980-06-11
US4239765A (en) 1980-12-16
EP0011770B1 (de) 1981-10-14
JPS638938B2 (es) 1988-02-25
DE2851143A1 (de) 1980-06-04
JPS5573661A (en) 1980-06-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601