ES485157A1 - Procedimiento para la obtencion de esteres de acido benzimi-dazolilcarbamico,de efecto antihelmintico - Google Patents

Procedimiento para la obtencion de esteres de acido benzimi-dazolilcarbamico,de efecto antihelmintico

Info

Publication number
ES485157A1
ES485157A1 ES485157A ES485157A ES485157A1 ES 485157 A1 ES485157 A1 ES 485157A1 ES 485157 A ES485157 A ES 485157A ES 485157 A ES485157 A ES 485157A ES 485157 A1 ES485157 A1 ES 485157A1
Authority
ES
Spain
Prior art keywords
acid esters
benzimidazolyl
preparation
carbamic acid
medicaments based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485157A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES485157A1 publication Critical patent/ES485157A1/es
Priority claimed from AU12079/83A external-priority patent/AU1207983A/en
Priority claimed from AU12078/83A external-priority patent/AU1207883A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Abstract

Procedimiento para la obtención de esteres de ácido benzimidazolilcarbámico, de efecto antihelmíntico de fórmula **(Fórmula)** donde X significa un átomo de azufre, un átomo de oxigeno, el grupo SO o el grupo SO2, Z significa un grupo alquilo con 1 hasta ó átomos de carbono, que en caso dado puede estar sustituido, R significa el grupo NH2, NHR1 o el grupo NR1R2, donde los sustituyentes R1 y R2 pueden ser iguales o diferentes y significan alquilo, en caso dado sustituido, fenilo, en caso dado sustituido, o fenialquilo, en caso dado sustituido, o donde R1 de los grupos NHR1 o NR1R2 puede estar enlazado con un átomo de carbono de sustituyente Z a un anillo de 5 hasta 7 miembros, en caso dado sustituido, o donde la los restos R1 y R2 junto con el átomo de nitrógeno pueden formar un resto azabicicloalquilo, en caso dado sustituido, con 6 hasta 10 miembros de anillo, o donde R significa un grupo cicloalquilenimino, cicloalquenilimino o cicloalcandienilenino.
ES485157A 1978-10-19 1979-10-18 Procedimiento para la obtencion de esteres de acido benzimi-dazolilcarbamico,de efecto antihelmintico Expired ES485157A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19782845537 DE2845537A1 (de) 1978-10-19 1978-10-19 Benzimidazolylcarbamidsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AU12079/83A AU1207983A (en) 1978-10-19 1983-03-07 Benzimidazolylcarbamic acid esters
AU12078/83A AU1207883A (en) 1978-10-19 1983-03-07 Benzimidazolylcarbamic acid esters

Publications (1)

Publication Number Publication Date
ES485157A1 true ES485157A1 (es) 1980-05-16

Family

ID=34279107

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485157A Expired ES485157A1 (es) 1978-10-19 1979-10-18 Procedimiento para la obtencion de esteres de acido benzimi-dazolilcarbamico,de efecto antihelmintico

Country Status (11)

Country Link
US (2) US4287199A (es)
EP (1) EP0010242B1 (es)
JP (1) JPS5557569A (es)
AR (2) AR222502A1 (es)
AU (1) AU535251B2 (es)
DE (2) DE2845537A1 (es)
DK (1) DK440279A (es)
ES (1) ES485157A1 (es)
NO (1) NO793202L (es)
NZ (1) NZ191857A (es)
ZA (1) ZA795565B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138575A1 (de) * 1981-09-28 1983-04-07 Basf Ag, 6700 Ludwigshafen Fungizid
US5278181A (en) * 1992-05-12 1994-01-11 Board Of Regents Acting On Behalf Of The University Of Michigan Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics
PE20000728A1 (es) * 1998-06-26 2000-08-21 Cocensys Inc Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda
EP2643304A2 (en) * 2010-11-24 2013-10-02 Sequent Scientific Ltd. A process for preparation of albendazole

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3682952A (en) * 1964-08-04 1972-08-08 Smith Kline French Lab 5(6)-n-butyl-2-carbomethoxy-benzimidazole
US3929824A (en) * 1972-12-29 1975-12-30 Syntex Inc 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3929821A (en) * 1972-12-29 1975-12-30 Syntex Inc 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles
US3901901A (en) * 1973-06-19 1975-08-26 Syntex Inc 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3929823A (en) * 1973-11-21 1975-12-30 Syntex Inc 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4025638A (en) * 1975-03-10 1977-05-24 Smithkline Corporation Methods and compositions using 5-cycloalkylthio- and oxy-2-carbalkoxy-aminobenzimidazole
US4026936A (en) * 1975-08-07 1977-05-31 Hoffmann-La Roche Inc. Anthelmintic pyridine and thiazole substituted benzimidazole carbamates
CA1094061A (en) * 1976-03-19 1981-01-20 Colin C. Beard 5(6)-benzene ring substituted benzimidazole-2- carbamate derivatives having anthelmintic activity
US4046908A (en) * 1976-07-16 1977-09-06 E. R. Squibb & Sons, Inc. Benzimidazole derivatives, compositions thereof and method of use as anthelmintics
US4093732A (en) * 1977-02-17 1978-06-06 E. R. Squibb & Sons, Inc. Sulfoxide derivatives of benzimidazoles
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
US4145431A (en) * 1978-02-16 1979-03-20 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral administration of sulfide- and sulfoxide-derivatives of benzimidazoles
US4174400A (en) * 1978-09-13 1979-11-13 Merck & Co., Inc. Anthelmintic benzimidazoles

Also Published As

Publication number Publication date
DK440279A (da) 1980-04-20
EP0010242B1 (de) 1982-09-29
DE2963782D1 (en) 1982-11-11
JPS5557569A (en) 1980-04-28
NO793202L (no) 1980-04-22
NZ191857A (en) 1982-05-31
EP0010242A1 (de) 1980-04-30
US4353913A (en) 1982-10-12
AR223588A1 (es) 1981-08-31
AR222502A1 (es) 1981-05-29
ZA795565B (en) 1980-10-29
AU535251B2 (en) 1984-03-08
DE2845537A1 (de) 1980-04-30
US4287199A (en) 1981-09-01
AU5179179A (en) 1980-06-26

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