ES8203897A1 - Procedimiento para la obtencion de imidazoazoalquenamidas - Google Patents
Procedimiento para la obtencion de imidazoazoalquenamidasInfo
- Publication number
- ES8203897A1 ES8203897A1 ES502573A ES502573A ES8203897A1 ES 8203897 A1 ES8203897 A1 ES 8203897A1 ES 502573 A ES502573 A ES 502573A ES 502573 A ES502573 A ES 502573A ES 8203897 A1 ES8203897 A1 ES 8203897A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- imidazoazolalkenyl
- carboxamides
- medicaments
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE IMIDAZOAZOALQUENAMIDAS. CONSITE EN HACER REACCIONAR COMPUESTOS DE FORMULA GENERAL (I) CON DERIVADOS DE FOSFONATO (II) EN PRESENCIA DE BASES FUERTES Y DISOLVENTES ORGANICOS INERTES A TEMPERATURAS COMPRENDIDAS ENTRE -20 Y 40 GRADOS C. OPCIONALMENTE, SE PUEDE HACER REACCIONAR COMPUESTOS DE CARBONILO CON DERIVADOS DE ACETAMIDA EN PRESENCIA DE CATALIZADORES Y, EN CASO DADO, DE DISOLVENTES ORGANICOS INERTES A TEMPERATURAS DE 20 A 200 GRADOS C, O SE HACE REACCIONAR ACIDOS ALQUENICOS CON AMIDAS EN PRESENCIA DE DISOLVENTE ORGANICOS INERTES A TEMPERATURA DE 20 Y 150 GRADOS C.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803020421 DE3020421A1 (de) | 1980-05-29 | 1980-05-29 | Imidazoazolalkensaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln |
DE19803043158 DE3043158A1 (de) | 1980-11-15 | 1980-11-15 | Imidazoazolalkensaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln |
Publications (2)
Publication Number | Publication Date |
---|---|
ES502573A0 ES502573A0 (es) | 1982-04-01 |
ES8203897A1 true ES8203897A1 (es) | 1982-04-01 |
Family
ID=25785736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES502573A Expired ES8203897A1 (es) | 1980-05-29 | 1981-05-28 | Procedimiento para la obtencion de imidazoazoalquenamidas |
Country Status (13)
Country | Link |
---|---|
US (1) | US4444770A (es) |
EP (1) | EP0041215B1 (es) |
AU (1) | AU543307B2 (es) |
CA (1) | CA1188690A (es) |
DE (1) | DE3173607D1 (es) |
DK (1) | DK233281A (es) |
ES (1) | ES8203897A1 (es) |
FI (1) | FI70900C (es) |
GR (1) | GR74557B (es) |
HU (1) | HU186887B (es) |
IL (1) | IL62960A (es) |
NO (2) | NO811630L (es) |
PT (1) | PT73058B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3208437A1 (de) * | 1982-03-09 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Imidazothiadiazolalkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln |
DE3329621A1 (de) * | 1983-08-17 | 1985-02-28 | Bayer Ag, 5090 Leverkusen | Aminoalkyl-imidazothiadiazol-alkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln |
IT1213175B (it) * | 1984-06-06 | 1989-12-14 | Mediolanum Farmaceutici Srl | Derivati imidazotiazolmetilen-acetidrazidi, loro preparazione e composizioni farmaceutiche ad attivita'diuretica. |
DE3542661A1 (de) * | 1985-12-03 | 1987-06-04 | Bayer Ag | Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung |
DE3542662A1 (de) * | 1985-12-03 | 1987-06-04 | Bayer Ag | Imidazothiadiazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten |
TW438796B (en) * | 1996-05-15 | 2001-06-07 | Hoffmann La Roche | 2,4-diaminopyrimidine derivatives, the manufacture process thereof, and the antibiotically-active pharmaceutical composition containing the same |
US20060135571A1 (en) * | 2003-06-13 | 2006-06-22 | Jaquith James B | Imidazo(2,1-b)-1,3,4-thiadiazole sulfoxides and sulfones |
DE102005010215A1 (de) * | 2005-03-05 | 2006-09-07 | Bayer Cropscience Ag | Heterobicyclische Acrylamide |
CN101878219B (zh) | 2007-09-27 | 2014-04-02 | 西班牙国家癌症研究中心 | 用于作为蛋白激酶抑制剂使用的咪唑并噻二唑类 |
US8318928B2 (en) * | 2008-12-15 | 2012-11-27 | Glenmark Pharmaceuticals, S.A. | Fused imidazole carboxamides as TRPV3 modulators |
EP2414369B1 (en) | 2009-04-02 | 2015-08-12 | Fundación Centro Nacional de Investigaciones Oncológicas Carlos III | Imidazo[2,1-b][1,3,4]thiadiazole derivatives |
EP2488533B1 (en) * | 2009-10-13 | 2014-07-23 | Council of Scientific & Industrial Research | Imidazothiazole-chalcone derivatives as potential anticancer agents and process for the preparation thereof |
US20130035325A1 (en) * | 2009-11-16 | 2013-02-07 | The Regents Of The University Of California | Kinase inhibitors |
JP6101343B2 (ja) | 2012-04-26 | 2017-03-22 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 血小板凝集を治療するためのプロテアーゼ活性化受容体4(par4)阻害剤としてのイミダゾチアジアゾールおよびイミダゾピリダジン誘導体 |
KR20200127273A (ko) | 2012-04-26 | 2020-11-10 | 브리스톨-마이어스 스큅 컴퍼니 | 혈소판 응집을 치료하기 위한 프로테아제 활성화 수용체 4 (par4) 억제제로서의 이미다조티아디아졸 및 이미다조피라진 유도체 |
CA2871637A1 (en) | 2012-04-26 | 2013-10-31 | Bristol-Myers Squibb Company | Imidazothiadiazole derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
WO2018005591A1 (en) | 2016-06-29 | 2018-01-04 | Universite De Montreal | Biarylmethyl heterocycles |
CA3158333A1 (en) | 2019-10-21 | 2021-04-29 | Novartis Ag | Compounds and compositions for the treatment of parasitic diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3615639A (en) * | 1967-10-23 | 1971-10-26 | Eastman Kodak Co | Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers |
US3804823A (en) * | 1972-02-15 | 1974-04-16 | Eastman Kodak Co | Heterocyclic containing monoazo compounds |
US4042583A (en) * | 1973-09-20 | 1977-08-16 | Pfizer Inc. | Imidazo[2,1-b]thiazole and thiazolo[3,2-a]-benzimidazole quaternary salts as hypoglycemic agents and growth promotants |
OA04806A (fr) * | 1973-12-10 | 1980-08-31 | Bayer Ag | Nouveaux esters triazolothiazolyliques d'acide (thiono)-phosphorique (phosphonique), leur procédé de préparation et leur application comme insecticides et acaricides. |
AT340414B (de) * | 1975-02-18 | 1977-12-12 | Plantex Ltd | Verfahren zur herstellung von neuen imidazo(2,1-b)thiazolderivaten und ihren salzen |
US4263311A (en) * | 1976-09-27 | 1981-04-21 | Smithkline Corporation | 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles |
DE2823686A1 (de) * | 1978-05-31 | 1979-12-06 | Bayer Ag | Imidazo eckige klammer auf 2.1-b eckige klammer zu eckige klammer auf 1.3.4 eckige klammer zu -thiadiazole |
DE2902763A1 (de) * | 1979-01-25 | 1980-08-07 | Basf Ag | Basische farbstoffe |
-
1981
- 1981-05-13 US US06/263,400 patent/US4444770A/en not_active Expired - Fee Related
- 1981-05-13 NO NO811630A patent/NO811630L/no unknown
- 1981-05-20 PT PT73058A patent/PT73058B/pt unknown
- 1981-05-21 AU AU70900/81A patent/AU543307B2/en not_active Ceased
- 1981-05-25 DE DE8181104000T patent/DE3173607D1/de not_active Expired
- 1981-05-25 EP EP81104000A patent/EP0041215B1/de not_active Expired
- 1981-05-26 IL IL62960A patent/IL62960A/xx unknown
- 1981-05-27 DK DK233281A patent/DK233281A/da not_active Application Discontinuation
- 1981-05-27 FI FI811630A patent/FI70900C/fi not_active IP Right Cessation
- 1981-05-27 CA CA000378454A patent/CA1188690A/en not_active Expired
- 1981-05-27 GR GR65080A patent/GR74557B/el unknown
- 1981-05-28 ES ES502573A patent/ES8203897A1/es not_active Expired
- 1981-05-28 HU HU811597A patent/HU186887B/hu unknown
-
1985
- 1985-11-22 NO NO854688A patent/NO854688L/no unknown
Also Published As
Publication number | Publication date |
---|---|
IL62960A0 (en) | 1981-07-31 |
ES502573A0 (es) | 1982-04-01 |
NO811630L (no) | 1981-11-30 |
FI811630L (fi) | 1981-11-30 |
HU186887B (en) | 1985-10-28 |
DE3173607D1 (en) | 1986-03-13 |
US4444770A (en) | 1984-04-24 |
PT73058B (en) | 1982-07-01 |
IL62960A (en) | 1986-04-29 |
EP0041215A3 (en) | 1982-04-14 |
CA1188690A (en) | 1985-06-11 |
DK233281A (da) | 1981-11-30 |
EP0041215A2 (de) | 1981-12-09 |
AU7090081A (en) | 1981-12-03 |
EP0041215B1 (de) | 1986-01-29 |
PT73058A (en) | 1981-06-01 |
GR74557B (es) | 1984-06-29 |
FI70900B (fi) | 1986-07-18 |
AU543307B2 (en) | 1985-04-18 |
NO854688L (no) | 1981-11-30 |
FI70900C (fi) | 1986-10-27 |
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