ES8401064A1 - Procedimiento para la obtencion de azolil-fenoxi-tetrahidrofuran-2-iliden-metanos. - Google Patents
Procedimiento para la obtencion de azolil-fenoxi-tetrahidrofuran-2-iliden-metanos.Info
- Publication number
- ES8401064A1 ES8401064A1 ES519690A ES519690A ES8401064A1 ES 8401064 A1 ES8401064 A1 ES 8401064A1 ES 519690 A ES519690 A ES 519690A ES 519690 A ES519690 A ES 519690A ES 8401064 A1 ES8401064 A1 ES 8401064A1
- Authority
- ES
- Spain
- Prior art keywords
- methanes
- azolyl
- ylidene
- phenoxy
- tetrahydrofuran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/28—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Noodles (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE AZOLILFENOXITETRAHIDRO FURAN-2-ILIDENMETANOS Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE A ES NITROGENO O CH; Y R ES FENILO OPCIONALMENTE SUSTITUIDO.CONSISTE EN LA REACCION DE HALOGENO-ETER CETONAS DE FORMULA (II), EN LA QUE X E Y SON HALOGENOS, Y R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON IMIDAZOL O 1,2,4-TRIAZOL. LA REACCION SE LLEVA A CABO EN UN DILUYENTE INERTE, EN PRESENCIA DE UN ACEPTOR DE ACIDO, A UNA TEMPERATURA PROXIMA A 90JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICASPOR SU ACTIVIDAD ANTIMICOTICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823204795 DE3204795A1 (de) | 1982-02-11 | 1982-02-11 | Azolyl-phenoxy-tetrahydrofuran-2-yliden-methane, verfahren zu ihrer herstellung sowie antimikrobielle mittel, die diese stoffe enthalten |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401064A1 true ES8401064A1 (es) | 1983-12-01 |
ES519690A0 ES519690A0 (es) | 1983-12-01 |
Family
ID=6155408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES519690A Granted ES519690A0 (es) | 1982-02-11 | 1983-02-10 | Procedimiento para la obtencion de azolil-fenoxi-tetrahidrofuran-2-iliden-metanos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4487776A (es) |
EP (1) | EP0088874B1 (es) |
JP (1) | JPS58148881A (es) |
KR (1) | KR850001518B1 (es) |
AT (1) | ATE19079T1 (es) |
CA (1) | CA1199640A (es) |
DE (2) | DE3204795A1 (es) |
ES (1) | ES519690A0 (es) |
GR (1) | GR78106B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3204692A1 (de) * | 1982-02-11 | 1983-08-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2-chlormethylen-3,3-dimethyl-tetrahydrofuran |
DE3336859A1 (de) * | 1983-10-11 | 1985-04-25 | Bayer Ag, 5090 Leverkusen | Substituierte azolyl-tetrahydro-furan-2-yliden-methan-derivate |
DE3336861A1 (de) * | 1983-10-11 | 1985-04-25 | Bayer Ag, 5090 Leverkusen | Azolyl-tetrahydrofuran-2-yliden-methan-derivate |
CA1269994A (en) * | 1985-04-05 | 1990-06-05 | Noritada Matsuo | Method for producing cyclopropanecarboxylic acid derivatives |
DE3716023A1 (de) * | 1987-05-14 | 1988-12-08 | Bayer Ag | Azolyl-tetrahydrofuran-2-yliden-methane |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK3395372T3 (da) | 2009-02-20 | 2022-04-19 | Enhanx Biopharm Inc | System til afgivelse af glutathion-baseret medikament |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4259505A (en) * | 1980-03-04 | 1981-03-31 | Ciba-Geigy Corporation | Process for the preparation of 1H-azole derivatives |
-
1982
- 1982-02-11 DE DE19823204795 patent/DE3204795A1/de not_active Withdrawn
-
1983
- 1983-01-27 US US06/461,369 patent/US4487776A/en not_active Expired - Fee Related
- 1983-02-01 EP EP83100898A patent/EP0088874B1/de not_active Expired
- 1983-02-01 DE DE8383100898T patent/DE3362859D1/de not_active Expired
- 1983-02-01 AT AT83100898T patent/ATE19079T1/de active
- 1983-02-02 KR KR1019840000512A patent/KR850001518B1/ko not_active Application Discontinuation
- 1983-02-09 GR GR70456A patent/GR78106B/el unknown
- 1983-02-10 ES ES519690A patent/ES519690A0/es active Granted
- 1983-02-10 CA CA000421366A patent/CA1199640A/en not_active Expired
- 1983-02-10 JP JP58019903A patent/JPS58148881A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GR78106B (es) | 1984-09-26 |
EP0088874A3 (en) | 1984-07-18 |
DE3362859D1 (en) | 1986-05-15 |
KR850001518B1 (ko) | 1985-10-16 |
KR840003631A (ko) | 1984-09-15 |
CA1199640A (en) | 1986-01-21 |
JPS58148881A (ja) | 1983-09-05 |
ES519690A0 (es) | 1983-12-01 |
EP0088874A2 (de) | 1983-09-21 |
ATE19079T1 (de) | 1986-04-15 |
EP0088874B1 (de) | 1986-04-09 |
US4487776A (en) | 1984-12-11 |
DE3204795A1 (de) | 1983-08-18 |
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