ES480426A1 - Procedimiento para la obtencion de hidroxipropil-imidazoles. - Google Patents

Procedimiento para la obtencion de hidroxipropil-imidazoles.

Info

Publication number
ES480426A1
ES480426A1 ES480426A ES480426A ES480426A1 ES 480426 A1 ES480426 A1 ES 480426A1 ES 480426 A ES480426 A ES 480426A ES 480426 A ES480426 A ES 480426A ES 480426 A1 ES480426 A1 ES 480426A1
Authority
ES
Spain
Prior art keywords
preparation
medicaments containing
imidazoles
hydroxypropyl
hydroxypropyl imidazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480426A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782820489 external-priority patent/DE2820489A1/de
Priority claimed from DE19782832677 external-priority patent/DE2832677A1/de
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES480426A1 publication Critical patent/ES480426A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la obtención de hidroxipropilimidazoles de fórmula general **(Fórmula)** donde R significa fenilo, en caso dado sustituido, naftilo, ó tetrahidronaftilo, R1 significa fenilo, en caso dado sustituido, ó cicloalquilo y R2 significa hidrógeno, ó R1 y R2 juntos en la posición orto entre sí están por un puente metileno de varios miembros, en caso dado sustituido, ó junto con el anillo fenilo por naftilo, R3 significa halógeno, alquilo, alcoxi o halógenoalquilo, y n está por 0, 1, 2 ó 3, y sus sales de adición de ácido fisiológicamente compatibles.
ES480426A 1978-05-10 1979-05-10 Procedimiento para la obtencion de hidroxipropil-imidazoles. Expired ES480426A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782820489 DE2820489A1 (de) 1978-05-10 1978-05-10 Hydroxypropyl-imidazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE19782832677 DE2832677A1 (de) 1978-07-26 1978-07-26 Hydroxypropyl-imidazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES480426A1 true ES480426A1 (es) 1979-12-01

Family

ID=25774448

Family Applications (1)

Application Number Title Priority Date Filing Date
ES480426A Expired ES480426A1 (es) 1978-05-10 1979-05-10 Procedimiento para la obtencion de hidroxipropil-imidazoles.

Country Status (5)

Country Link
US (1) US4246274A (es)
EP (1) EP0005250B1 (es)
DE (1) DE2960621D1 (es)
ES (1) ES480426A1 (es)
IL (1) IL57229A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277486A (en) * 1979-03-09 1981-07-07 Syntex (U.S.A.) Inc. 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives
DE2920375A1 (de) * 1979-05-19 1980-11-20 Bayer Ag Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
DE3018865A1 (de) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen Antimikrobielle mittel
AU542623B2 (en) * 1980-05-16 1985-02-28 Bayer Aktiengesellschaft 1-hydroxyethyl-azole derivatives
US5006513A (en) * 1987-11-09 1991-04-09 Miles Inc. Antimycotic compositions of nikkomycin compounds and azole antimycotica
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US5096889A (en) * 1987-11-09 1992-03-17 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US4914087A (en) * 1988-02-29 1990-04-03 Bayer Ag Nikkomycin derivatives, antimycotic compositions of nikkomycin derivatives and azole antimycotics
FR3035664B1 (fr) 2015-04-29 2020-02-21 Malteries Soufflet Utilisation de cysteine endoprotease pour diminuer le trouble de boissons
CN111108105B (zh) 2017-09-22 2023-03-31 朱比兰特埃皮帕德有限公司 作为pad抑制剂的杂环化合物
WO2019077631A1 (en) 2017-10-18 2019-04-25 Jubilant Biosys Limited IMIDAZO-PYRIDINE COMPOUNDS FOR USE AS PAD INHIBITORS
KR20200085836A (ko) 2017-11-06 2020-07-15 주빌런트 프로델 엘엘씨 Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
BR112020010322A2 (pt) 2017-11-24 2020-11-17 Jubilant Episcribe Llc composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer
WO2019175897A1 (en) 2018-03-13 2019-09-19 Jubilant Biosys Limited Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2213863C3 (de) * 1972-03-22 1982-05-13 Bayer Ag, 5090 Leverkusen Disubstituierte Triphenylmethylimidazole, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2333354C2 (de) * 1973-06-30 1983-12-15 Bayer Ag, 5090 Leverkusen 2-Aryloxy-2-(imidazol-1-yl)-äthanole sowie deren Salze, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
DE2350123C2 (de) * 1973-10-05 1983-04-14 Bayer Ag, 5090 Leverkusen 1-Propyl-imidazol-Derivate und deren Salze, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
US4101664A (en) * 1975-10-06 1978-07-18 Janssen Pharmaceutica N.V. 1-(2-Ar-4-aryloxymethyl-1,3-dioxolan-2-ylmethyl)-imidazoles
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2705676A1 (de) * 1977-02-11 1978-08-17 Bayer Ag Fungizide mittel
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
DE2736122A1 (de) * 1977-08-11 1979-02-22 Basf Ag Fungizide

Also Published As

Publication number Publication date
US4246274A (en) 1981-01-20
IL57229A (en) 1982-08-31
IL57229A0 (en) 1979-09-30
EP0005250B1 (de) 1981-08-12
EP0005250A3 (en) 1979-12-12
DE2960621D1 (en) 1981-11-12
EP0005250A2 (de) 1979-11-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402