ZA811331B - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
ZA811331B
ZA811331B ZA00811331A ZA811331A ZA811331B ZA 811331 B ZA811331 B ZA 811331B ZA 00811331 A ZA00811331 A ZA 00811331A ZA 811331 A ZA811331 A ZA 811331A ZA 811331 B ZA811331 B ZA 811331B
Authority
ZA
South Africa
Prior art keywords
heterocyclic derivatives
heterocyclic
derivatives
Prior art date
Application number
ZA00811331A
Other languages
English (en)
Inventor
Clitherow John Watson
John Watson Clitherow
Bradshaw John
John Bradshaw
Mackinnon John Wils Macfarlane
John Wilson Macfarla Mackinnon
Judd Duncan Bruce
Duncan Bruce Judd
Bays David Edmund
David Edmund Bays
Hayes Roger
Roger Hayes
Pearce Andrew
Andrew Pearce
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA811331B publication Critical patent/ZA811331B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
ZA00811331A 1980-02-28 1981-02-27 Heterocyclic derivatives ZA811331B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8006806 1980-02-28

Publications (1)

Publication Number Publication Date
ZA811331B true ZA811331B (en) 1982-10-27

Family

ID=10511754

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00811331A ZA811331B (en) 1980-02-28 1981-02-27 Heterocyclic derivatives

Country Status (26)

Country Link
US (1) US4670448A (de)
JP (2) JPS56147777A (de)
KR (3) KR850000668B1 (de)
AT (2) AT380240B (de)
AU (1) AU544357B2 (de)
BE (1) BE887730A (de)
CA (1) CA1158649A (de)
CH (1) CH655104A5 (de)
CY (1) CY1335A (de)
DE (1) DE3107628A1 (de)
DK (1) DK90681A (de)
ES (4) ES499931A0 (de)
FI (1) FI76076C (de)
FR (1) FR2477150A1 (de)
GB (1) GB2075007B (de)
HK (1) HK69186A (de)
IE (1) IE50987B1 (de)
IL (1) IL62229A (de)
IT (1) IT1209846B (de)
KE (1) KE3629A (de)
MY (1) MY8500428A (de)
NL (2) NL186812C (de)
NO (1) NO810681L (de)
NZ (1) NZ196365A (de)
SE (1) SE448233B (de)
ZA (1) ZA811331B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57169452A (en) * 1981-04-14 1982-10-19 Teikoku Hormone Mfg Co Ltd Novel phenoxyalkylamide derivative
US4476126A (en) * 1981-06-11 1984-10-09 Glaxo Group Limited 1,2,4 Triazoze amines and their pharmaceutical use
ES8407030A1 (es) * 1982-02-24 1984-04-01 Glaxo Group Ltd Un procedimiento para prepararacion de derivados del triazol.
CA1189508A (en) * 1982-02-25 1985-06-25 Roger Hayes Heterocyclic derivatives as histamine h.sub.2- antagonists
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
GB8628475D0 (en) * 1986-11-28 1987-01-07 Glaxo Group Ltd Medicaments
GB8805268D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JP3328082B2 (ja) * 1994-12-13 2002-09-24 日本カーバイド工業株式会社 N−グアニジノチオ尿素塩及び3−アミノ−5−メルカプト−1,2,4−トリアゾールの製造方法
EP1223932A4 (de) 1999-10-01 2003-01-15 Smithkline Beecham Corp Verbindungen und verfahren
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム 1−置換―1―アミノグアニジン又はその塩、及びこれらの製造方法
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
DE3067920D1 (en) * 1979-03-02 1984-06-28 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
KR850000676B1 (ko) 1985-05-10
IE50987B1 (en) 1986-09-03
AU6793381A (en) 1981-09-03
KR850000682B1 (ko) 1985-05-14
ES8304954A1 (es) 1983-03-16
FI810619L (fi) 1981-08-29
KE3629A (en) 1986-05-16
NZ196365A (en) 1984-07-31
AT387774B (de) 1989-03-10
SE448233B (sv) 1987-02-02
DE3107628A1 (de) 1982-04-01
ES509669A0 (es) 1983-03-16
ES530741A0 (es) 1985-07-01
ES8506292A1 (es) 1985-07-01
GB2075007A (en) 1981-11-11
KR830005164A (ko) 1983-08-03
AU544357B2 (en) 1985-05-23
FR2477150A1 (fr) 1981-09-04
CH655104A5 (fr) 1986-03-27
FI76076B (fi) 1988-05-31
HK69186A (en) 1986-09-26
NL186812B (nl) 1990-10-01
IL62229A0 (en) 1981-03-31
ATA151084A (de) 1988-08-15
KR850002011A (ko) 1985-04-10
DK90681A (da) 1981-08-29
MY8500428A (en) 1985-12-31
FI76076C (fi) 1988-09-09
SE8101311L (sv) 1981-08-29
ES8205208A1 (es) 1982-06-01
ES8405775A1 (es) 1984-06-16
JPS6452763A (en) 1989-02-28
FR2477150B1 (de) 1984-03-16
GB2075007B (en) 1983-07-13
KR850000668B1 (ko) 1985-05-09
NL8802221A (nl) 1989-01-02
ES518305A0 (es) 1984-06-16
NO810681L (no) 1981-08-31
IE810431L (en) 1981-08-28
IT1209846B (it) 1989-08-30
US4670448A (en) 1987-06-02
CA1158649A (en) 1983-12-13
KR850002010A (ko) 1985-04-10
ES499931A0 (es) 1982-06-01
IL62229A (en) 1987-10-30
AT380240B (de) 1986-04-25
IT8147905A0 (it) 1981-02-27
CY1335A (en) 1986-10-24
NL186812C (nl) 1991-03-01
JPS56147777A (en) 1981-11-16
DE3107628C2 (de) 1991-03-14
NL8100979A (nl) 1981-10-01
BE887730A (fr) 1981-08-27
JPH0338269B2 (de) 1991-06-10
ATA93981A (de) 1985-09-15

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