KR850003301A - 옥소옥세판 유도체의 합성방법 - Google Patents

옥소옥세판 유도체의 합성방법

Info

Publication number
KR850003301A
KR850003301A KR1019840006472A KR840006472A KR850003301A KR 850003301 A KR850003301 A KR 850003301A KR 1019840006472 A KR1019840006472 A KR 1019840006472A KR 840006472 A KR840006472 A KR 840006472A KR 850003301 A KR850003301 A KR 850003301A
Authority
KR
South Korea
Prior art keywords
oxooxepan
synthesizing
derivatives
synthesizing oxooxepan
oxooxepan derivatives
Prior art date
Application number
KR1019840006472A
Other languages
English (en)
Other versions
KR850000227B1 (ko
Inventor
죠오지 하아죠오스 졸탄
폴 와치타아 밋첼
Original Assignee
오오소오 화아마슈이티칼 코오포레이숀
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/174,070 external-priority patent/US4276216A/en
Application filed by 오오소오 화아마슈이티칼 코오포레이숀 filed Critical 오오소오 화아마슈이티칼 코오포레이숀
Application granted granted Critical
Publication of KR850000227B1 publication Critical patent/KR850000227B1/ko
Publication of KR850003301A publication Critical patent/KR850003301A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019840006472A 1980-07-31 1984-10-17 옥소옥세판 유도체의 합성방법 KR850000227B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US174,070 1980-07-31
US06/174,070 US4276216A (en) 1980-07-31 1980-07-31 Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes
US23374881A 1981-02-12 1981-02-12
US233,748 1981-02-12
KR1019810002303A KR850000218B1 (ko) 1980-07-31 1981-06-25 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002303A Division KR850000218B1 (ko) 1980-07-31 1981-06-25 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법

Publications (2)

Publication Number Publication Date
KR850000227B1 KR850000227B1 (ko) 1985-03-11
KR850003301A true KR850003301A (ko) 1985-06-13

Family

ID=26869837

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1019810002303A KR850000218B1 (ko) 1980-07-31 1981-06-25 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법
KR1019840006472A KR850000227B1 (ko) 1980-07-31 1984-10-17 옥소옥세판 유도체의 합성방법
KR1019840006473A KR850000228B1 (ko) 1980-07-31 1984-10-18 메톡시이미노 옥세판 에스테르의 합성방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019810002303A KR850000218B1 (ko) 1980-07-31 1981-06-25 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019840006473A KR850000228B1 (ko) 1980-07-31 1984-10-18 메톡시이미노 옥세판 에스테르의 합성방법

Country Status (4)

Country Link
EP (2) EP0045631A3 (ko)
KR (3) KR850000218B1 (ko)
AU (2) AU543267B2 (ko)
CA (1) CA1171422A (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102907A (en) * 1990-09-13 1992-04-07 Merck & Co., Inc. Novel squalene synthetase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4176188A (en) * 1976-11-18 1979-11-27 Ortho Pharmaceutical Corp. Utero-evacuants
US4102895A (en) * 1976-11-18 1978-07-25 Ortho Pharmaceutical Corporation Oxepanes
US4182717A (en) * 1978-06-29 1980-01-08 Ortho Pharmaceutical Corp. Total synthesis of the utero-evacuant substance d,l-zoapatanol
US4215048A (en) * 1979-05-18 1980-07-29 Ortho Pharmaceutical Corporation Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4237055A (en) * 1979-06-18 1980-12-02 Ortho Pharmaceutical Corporation Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4276216A (en) * 1980-07-31 1981-06-30 Ortho Pharmaceutical Corporation Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes

Also Published As

Publication number Publication date
KR850000218B1 (ko) 1985-03-06
CA1171422A (en) 1984-07-24
EP0175427A1 (en) 1986-03-26
AU3820585A (en) 1985-05-30
KR850000228B1 (ko) 1985-03-11
KR850000227B1 (ko) 1985-03-11
EP0045631A2 (en) 1982-02-10
KR850003302A (ko) 1985-06-13
AU7215081A (en) 1982-02-04
AU543267B2 (en) 1985-04-18
EP0045631A3 (en) 1983-07-06
KR830006271A (ko) 1983-09-20

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Legal Events

Date Code Title Description
E701 Decision to grant or registration of patent right