NO322080B1 - 2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse. - Google Patents

2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse. Download PDF

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Publication number
NO322080B1
NO322080B1 NO19995751A NO995751A NO322080B1 NO 322080 B1 NO322080 B1 NO 322080B1 NO 19995751 A NO19995751 A NO 19995751A NO 995751 A NO995751 A NO 995751A NO 322080 B1 NO322080 B1 NO 322080B1
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NO
Norway
Prior art keywords
tnfa
acid
hiv
dione
benzyloxycarbonyl
Prior art date
Application number
NO19995751A
Other languages
English (en)
Norwegian (no)
Other versions
NO995751D0 (no
NO995751L (no
Inventor
George W Muller
David I Stirling
Roger Shen-Chu Chen
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of NO995751D0 publication Critical patent/NO995751D0/no
Publication of NO995751L publication Critical patent/NO995751L/no
Publication of NO322080B1 publication Critical patent/NO322080B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/45Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO19995751A 1997-05-30 1999-11-23 2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse. NO322080B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4827897P 1997-05-30 1997-05-30
PCT/US1998/010886 WO1998054170A1 (fr) 1997-05-30 1998-05-28 1-oxoisoindolines et 2-(2,6-dioxopiperidin-3-yl)-phtalimides substitues et procede pour reduire les taux de fnt alpha

Publications (3)

Publication Number Publication Date
NO995751D0 NO995751D0 (no) 1999-11-23
NO995751L NO995751L (no) 2000-01-28
NO322080B1 true NO322080B1 (no) 2006-08-14

Family

ID=21953674

Family Applications (6)

Application Number Title Priority Date Filing Date
NO19995751A NO322080B1 (no) 1997-05-30 1999-11-23 2,6-dioksopiperidiner samt farmasoytiske preparater som inneholder disse.
NO20061455A NO331367B1 (no) 1997-05-30 2006-03-30 1-okso-2-(2,6 dioksopiperidin-3-yl)-4-aminoisoindolin samt farmasoytisk sammensetning inneholdende en slik forbindelse
NO20092860A NO332270B1 (no) 1997-05-30 2009-08-18 Farmasoytisk sammensetning som omfatter 1,3-diokso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin og en farmasoytisk akseptabel eksipiens, fortynningsmiddel eller baerer
NO20111536A NO332271B1 (no) 1997-05-30 2011-11-08 2,6-dioksopiperidiner, anvendelse derav samt fremgangsmate for fremstilling av et medikament som inneholder en slik forbindelse
NO2012004C NO2012004I2 (no) 1997-05-30 2012-03-06 l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav
NO20120330A NO333641B1 (no) 1997-05-30 2012-03-20 2,6-dioksopiperidinderivater samt farmasoytiske preparater som inneholder disse

Family Applications After (5)

Application Number Title Priority Date Filing Date
NO20061455A NO331367B1 (no) 1997-05-30 2006-03-30 1-okso-2-(2,6 dioksopiperidin-3-yl)-4-aminoisoindolin samt farmasoytisk sammensetning inneholdende en slik forbindelse
NO20092860A NO332270B1 (no) 1997-05-30 2009-08-18 Farmasoytisk sammensetning som omfatter 1,3-diokso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin og en farmasoytisk akseptabel eksipiens, fortynningsmiddel eller baerer
NO20111536A NO332271B1 (no) 1997-05-30 2011-11-08 2,6-dioksopiperidiner, anvendelse derav samt fremgangsmate for fremstilling av et medikament som inneholder en slik forbindelse
NO2012004C NO2012004I2 (no) 1997-05-30 2012-03-06 l-okso-2-(2,6-dioksopiperidin-3-yl)-4-aminoisoindolin i racemisk form eller R-eller S-isomerer derav
NO20120330A NO333641B1 (no) 1997-05-30 2012-03-20 2,6-dioksopiperidinderivater samt farmasoytiske preparater som inneholder disse

Country Status (25)

Country Link
US (3) US6395754B1 (fr)
EP (3) EP1486496B1 (fr)
JP (2) JP4307567B2 (fr)
KR (1) KR100526212B1 (fr)
CN (3) CN1911927A (fr)
AT (2) ATE401319T1 (fr)
AU (1) AU741982B2 (fr)
CA (2) CA2291218C (fr)
CY (1) CY1108348T1 (fr)
CZ (1) CZ299812B6 (fr)
DE (2) DE69825994T2 (fr)
DK (2) DK0984955T3 (fr)
ES (3) ES2403102T3 (fr)
FI (1) FI19992490A (fr)
HK (1) HK1072248A1 (fr)
HU (2) HU228769B1 (fr)
MC (1) MC225A7 (fr)
NO (6) NO322080B1 (fr)
NZ (1) NZ501429A (fr)
PL (1) PL193276B1 (fr)
PT (2) PT1486496E (fr)
RU (1) RU2209207C2 (fr)
SK (1) SK163099A3 (fr)
TR (4) TR200000107T2 (fr)
WO (1) WO1998054170A1 (fr)

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