ITUB20169994A1 - Nuove forme cristalline di farmaci immunomodulatori - Google Patents
Nuove forme cristalline di farmaci immunomodulatoriInfo
- Publication number
- ITUB20169994A1 ITUB20169994A1 ITUB2016A009994A ITUB20169994A ITUB20169994A1 IT UB20169994 A1 ITUB20169994 A1 IT UB20169994A1 IT UB2016A009994 A ITUB2016A009994 A IT UB2016A009994A IT UB20169994 A ITUB20169994 A IT UB20169994A IT UB20169994 A1 ITUB20169994 A1 IT UB20169994A1
- Authority
- IT
- Italy
- Prior art keywords
- crystalline forms
- new crystalline
- immunomodulatory drugs
- immunomodulatory
- drugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2016A009994A ITUB20169994A1 (it) | 2016-01-14 | 2016-01-14 | Nuove forme cristalline di farmaci immunomodulatori |
EP16801233.4A EP3397626B1 (en) | 2016-01-14 | 2016-11-24 | Process for the purification of immunomodulatory drug pomalidomide using a co-crystal with gentisic acid |
PCT/EP2016/078726 WO2017121530A1 (en) | 2016-01-14 | 2016-11-24 | Crystal forms of immunomodulatory drug pomalidomide and co-crystal with gentisic acid |
JP2017556876A JP2018515477A (ja) | 2016-01-14 | 2016-11-24 | 免疫調節薬の新規な結晶形 |
US15/560,723 US10155740B2 (en) | 2016-01-14 | 2016-11-24 | Crystal forms of immunomodulatory drug pomalidomide and co-crystal with gentisic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2016A009994A ITUB20169994A1 (it) | 2016-01-14 | 2016-01-14 | Nuove forme cristalline di farmaci immunomodulatori |
Publications (1)
Publication Number | Publication Date |
---|---|
ITUB20169994A1 true ITUB20169994A1 (it) | 2017-07-14 |
Family
ID=55861097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITUB2016A009994A ITUB20169994A1 (it) | 2016-01-14 | 2016-01-14 | Nuove forme cristalline di farmaci immunomodulatori |
Country Status (5)
Country | Link |
---|---|
US (1) | US10155740B2 (it) |
EP (1) | EP3397626B1 (it) |
JP (1) | JP2018515477A (it) |
IT (1) | ITUB20169994A1 (it) |
WO (1) | WO2017121530A1 (it) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014170909A2 (en) | 2013-04-01 | 2014-10-23 | Hetero Research Foundation | Process for pomalidomide |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011050962A1 (en) * | 2009-10-29 | 2011-05-05 | Ratiopharm Gmbh | Acid addition salts of lenalidomide |
CN103626738A (zh) * | 2013-12-23 | 2014-03-12 | 重庆泰濠制药有限公司 | 一种泊马度胺晶型及其制备方法 |
WO2014160690A1 (en) * | 2013-03-26 | 2014-10-02 | Celgene Corporation | Solid forms comprising 4-amino-2-(2.6-dioxopiperidine-3-yl) isoindoline-1,3-dione and a coformer, compositions and methods of use thereof |
WO2014170909A2 (en) * | 2013-04-01 | 2014-10-23 | Hetero Research Foundation | Process for pomalidomide |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2701709B1 (fr) * | 1993-02-17 | 1995-04-07 | Rhone Poulenc Rorer Sa | Forme purifiée de streptograminés, sa préparation et les compositions pharmaceutiques qui la contiennent. |
US6281230B1 (en) | 1996-07-24 | 2001-08-28 | Celgene Corporation | Isoindolines, method of use, and pharmaceutical compositions |
US5635517B1 (en) | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
HU228769B1 (en) | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
JP5069905B2 (ja) * | 2003-01-21 | 2012-11-07 | アプテュイト (ウエスト ラファイエット)、エルエルシー | 新規な共結晶化 |
ME01513B (me) | 2005-06-30 | 2014-04-20 | Celgene Corp | Postupak dobijanja spojeva 4-amin0-2-(2,6-dioksopiperidin-3-il)izoindolin-1,3-diona |
WO2013012485A2 (en) | 2011-07-19 | 2013-01-24 | Amplio Pharma, Llc | Novel crystalline forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
WO2013126326A1 (en) | 2012-02-21 | 2013-08-29 | Celgene Corporation | Solid forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, compositions and methods of use thereof |
CN103288797B (zh) | 2013-05-17 | 2016-03-02 | 宁波百思佳医药科技有限公司 | 一种用亚砜类溶剂纯化Pomalidomide的方法 |
CN103275062B (zh) * | 2013-05-17 | 2016-04-13 | 宁波百思佳医药科技有限公司 | 一种Pomalidomide的纯化方法 |
PT107166B (pt) * | 2013-09-16 | 2018-12-28 | Hovione Farm S A | Síntese e engenharia de partículas de cocristais |
-
2016
- 2016-01-14 IT ITUB2016A009994A patent/ITUB20169994A1/it unknown
- 2016-11-24 US US15/560,723 patent/US10155740B2/en active Active
- 2016-11-24 WO PCT/EP2016/078726 patent/WO2017121530A1/en active Application Filing
- 2016-11-24 EP EP16801233.4A patent/EP3397626B1/en active Active
- 2016-11-24 JP JP2017556876A patent/JP2018515477A/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011050962A1 (en) * | 2009-10-29 | 2011-05-05 | Ratiopharm Gmbh | Acid addition salts of lenalidomide |
WO2014160690A1 (en) * | 2013-03-26 | 2014-10-02 | Celgene Corporation | Solid forms comprising 4-amino-2-(2.6-dioxopiperidine-3-yl) isoindoline-1,3-dione and a coformer, compositions and methods of use thereof |
WO2014170909A2 (en) * | 2013-04-01 | 2014-10-23 | Hetero Research Foundation | Process for pomalidomide |
CN103626738A (zh) * | 2013-12-23 | 2014-03-12 | 重庆泰濠制药有限公司 | 一种泊马度胺晶型及其制备方法 |
Non-Patent Citations (1)
Title |
---|
VISHWESHWAR P ET AL: "Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients", CHEMICAL COMMUNICATIONS - CHEMCOM; [6015D], ROYAL SOCIETY OF CHEMISTRY, GB, no. 36, 28 September 2005 (2005-09-28), pages 4601 - 4603, XP002565290, ISSN: 1359-7345, DOI: 10.1039/B501304F * |
Also Published As
Publication number | Publication date |
---|---|
JP2018515477A (ja) | 2018-06-14 |
EP3397626B1 (en) | 2020-10-28 |
US10155740B2 (en) | 2018-12-18 |
WO2017121530A1 (en) | 2017-07-20 |
EP3397626A1 (en) | 2018-11-07 |
US20180099944A1 (en) | 2018-04-12 |
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