ITUB20161079A1 - Procedimento per la preparazione di sofosbuvir - Google Patents
Procedimento per la preparazione di sofosbuvirInfo
- Publication number
- ITUB20161079A1 ITUB20161079A1 ITUB2016A001079A ITUB20161079A ITUB20161079A1 IT UB20161079 A1 ITUB20161079 A1 IT UB20161079A1 IT UB2016A001079 A ITUB2016A001079 A IT UB2016A001079A IT UB20161079 A ITUB20161079 A IT UB20161079A IT UB20161079 A1 ITUB20161079 A1 IT UB20161079A1
- Authority
- IT
- Italy
- Prior art keywords
- sofosbuvir
- procedure
- preparation
- Prior art date
Links
- TTZHDVOVKQGIBA-IQWMDFIBSA-N sofosbuvir Chemical compound N1([C@@H]2O[C@@H]([C@H]([C@]2(F)C)O)CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC=2C=CC=CC=2)C=CC(=O)NC1=O TTZHDVOVKQGIBA-IQWMDFIBSA-N 0.000 title 1
- 229960002063 sofosbuvir Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2016A001079A ITUB20161079A1 (it) | 2016-02-25 | 2016-02-25 | Procedimento per la preparazione di sofosbuvir |
| US15/358,850 US10112967B2 (en) | 2016-02-25 | 2016-11-22 | Process for the preparation of sofosbuvir |
| ES17705157T ES2936819T3 (es) | 2016-02-25 | 2017-02-20 | Procedimiento de preparación de sofosbuvir |
| EP17705157.0A EP3419983B1 (en) | 2016-02-25 | 2017-02-20 | Process for the preparation of sofosbuvir |
| PCT/EP2017/053815 WO2017144423A1 (en) | 2016-02-25 | 2017-02-20 | Process for the preparation of sofosbuvir |
| ARP170100460A AR107712A1 (es) | 2016-02-25 | 2017-02-23 | Proceso para preparar sofosbuvir |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2016A001079A ITUB20161079A1 (it) | 2016-02-25 | 2016-02-25 | Procedimento per la preparazione di sofosbuvir |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITUB20161079A1 true ITUB20161079A1 (it) | 2017-08-25 |
Family
ID=56134469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITUB2016A001079A ITUB20161079A1 (it) | 2016-02-25 | 2016-02-25 | Procedimento per la preparazione di sofosbuvir |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10112967B2 (it) |
| EP (1) | EP3419983B1 (it) |
| AR (1) | AR107712A1 (it) |
| ES (1) | ES2936819T3 (it) |
| IT (1) | ITUB20161079A1 (it) |
| WO (1) | WO2017144423A1 (it) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7964580B2 (en) | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
| WO2015017713A1 (en) | 2013-08-01 | 2015-02-05 | Idenix Pharmaceuticals, Inc. | D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease |
| EP3105238A4 (en) | 2014-02-13 | 2017-11-08 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
| WO2015123353A1 (en) | 2014-02-14 | 2015-08-20 | Kci Licensing, Inc. | Systems and methods for increasing absorbent capacity of a dressing |
| CN104327138B (zh) | 2014-10-21 | 2017-05-10 | 齐鲁制药有限公司 | Psi‑7977中间体化合物的制备方法 |
-
2016
- 2016-02-25 IT ITUB2016A001079A patent/ITUB20161079A1/it unknown
- 2016-11-22 US US15/358,850 patent/US10112967B2/en active Active
-
2017
- 2017-02-20 EP EP17705157.0A patent/EP3419983B1/en active Active
- 2017-02-20 WO PCT/EP2017/053815 patent/WO2017144423A1/en not_active Ceased
- 2017-02-20 ES ES17705157T patent/ES2936819T3/es active Active
- 2017-02-23 AR ARP170100460A patent/AR107712A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017144423A1 (en) | 2017-08-31 |
| EP3419983A1 (en) | 2019-01-02 |
| US20170247404A1 (en) | 2017-08-31 |
| ES2936819T3 (es) | 2023-03-22 |
| US10112967B2 (en) | 2018-10-30 |
| EP3419983B1 (en) | 2022-10-26 |
| AR107712A1 (es) | 2018-05-23 |
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