NO314562B1 - Enzymbasert fôradditiv, samt fôr inneholdende dette - Google Patents
Enzymbasert fôradditiv, samt fôr inneholdende dette Download PDFInfo
- Publication number
- NO314562B1 NO314562B1 NO19953218A NO953218A NO314562B1 NO 314562 B1 NO314562 B1 NO 314562B1 NO 19953218 A NO19953218 A NO 19953218A NO 953218 A NO953218 A NO 953218A NO 314562 B1 NO314562 B1 NO 314562B1
- Authority
- NO
- Norway
- Prior art keywords
- enzyme
- cellulase
- additive
- egi
- egii
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title claims description 71
- 108090000790 Enzymes Proteins 0.000 title claims description 71
- 239000003674 animal food additive Substances 0.000 title description 7
- 108010059892 Cellulase Proteins 0.000 claims abstract description 179
- 241000223262 Trichoderma longibrachiatum Species 0.000 claims abstract description 36
- 238000010353 genetic engineering Methods 0.000 claims abstract description 5
- 229940106157 cellulase Drugs 0.000 claims description 83
- 229940088598 enzyme Drugs 0.000 claims description 70
- 229920002678 cellulose Polymers 0.000 claims description 60
- 239000001913 cellulose Substances 0.000 claims description 59
- 101710126559 Endoglucanase EG-II Proteins 0.000 claims description 50
- 230000027455 binding Effects 0.000 claims description 42
- 238000000034 method Methods 0.000 claims description 40
- 239000000654 additive Substances 0.000 claims description 39
- 230000000996 additive effect Effects 0.000 claims description 35
- 235000013339 cereals Nutrition 0.000 claims description 32
- 241001465754 Metazoa Species 0.000 claims description 30
- 241000223259 Trichoderma Species 0.000 claims description 26
- 108010008885 Cellulose 1,4-beta-Cellobiosidase Proteins 0.000 claims description 19
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 claims description 19
- 235000007340 Hordeum vulgare Nutrition 0.000 claims description 14
- 108090000787 Subtilisin Proteins 0.000 claims description 9
- 241000223261 Trichoderma viride Species 0.000 claims description 9
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 241000209140 Triticum Species 0.000 claims description 7
- 235000021307 Triticum Nutrition 0.000 claims description 7
- 241000499912 Trichoderma reesei Species 0.000 claims description 6
- 240000008042 Zea mays Species 0.000 claims description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 6
- 108091005804 Peptidases Proteins 0.000 claims description 5
- 239000004365 Protease Substances 0.000 claims description 4
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 4
- 235000013373 food additive Nutrition 0.000 claims description 4
- 239000002778 food additive Substances 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 3
- 235000007238 Secale cereale Nutrition 0.000 claims description 3
- 244000082988 Secale cereale Species 0.000 claims description 3
- 235000019714 Triticale Nutrition 0.000 claims description 3
- 241000228158 x Triticosecale Species 0.000 claims description 3
- 108010011619 6-Phytase Proteins 0.000 claims description 2
- 102100032487 Beta-mannosidase Human genes 0.000 claims description 2
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 claims description 2
- 102100022624 Glucoamylase Human genes 0.000 claims description 2
- 102000004882 Lipase Human genes 0.000 claims description 2
- 108090001060 Lipase Proteins 0.000 claims description 2
- 239000004367 Lipase Substances 0.000 claims description 2
- 108010059820 Polygalacturonase Proteins 0.000 claims description 2
- 108090000637 alpha-Amylases Proteins 0.000 claims description 2
- 102000004139 alpha-Amylases Human genes 0.000 claims description 2
- 229940024171 alpha-amylase Drugs 0.000 claims description 2
- 108010055059 beta-Mannosidase Proteins 0.000 claims description 2
- 108010093305 exopolygalacturonase Proteins 0.000 claims description 2
- 235000019421 lipase Nutrition 0.000 claims description 2
- 229940085127 phytase Drugs 0.000 claims description 2
- 240000005979 Hordeum vulgare Species 0.000 claims 2
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims 1
- 235000009973 maize Nutrition 0.000 claims 1
- 108020004414 DNA Proteins 0.000 abstract description 32
- 239000012634 fragment Substances 0.000 abstract description 29
- 230000002538 fungal effect Effects 0.000 abstract description 12
- 108010084185 Cellulases Proteins 0.000 abstract description 10
- 102000005575 Cellulases Human genes 0.000 abstract description 10
- 230000014509 gene expression Effects 0.000 abstract description 10
- 239000013604 expression vector Substances 0.000 abstract description 7
- 238000010367 cloning Methods 0.000 abstract description 4
- 102000053602 DNA Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 description 67
- 230000000694 effects Effects 0.000 description 63
- 235000010980 cellulose Nutrition 0.000 description 58
- 239000000243 solution Substances 0.000 description 39
- 239000000203 mixture Substances 0.000 description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 26
- 230000003197 catalytic effect Effects 0.000 description 25
- 102000004169 proteins and genes Human genes 0.000 description 25
- 239000012153 distilled water Substances 0.000 description 21
- 210000004027 cell Anatomy 0.000 description 19
- 229920001503 Glucan Polymers 0.000 description 16
- 108010076504 Protein Sorting Signals Proteins 0.000 description 16
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 16
- 229960001031 glucose Drugs 0.000 description 16
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 description 15
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
- 150000001413 amino acids Chemical class 0.000 description 15
- 239000008103 glucose Substances 0.000 description 15
- 239000000463 material Substances 0.000 description 15
- 239000000758 substrate Substances 0.000 description 15
- 229920002498 Beta-glucan Polymers 0.000 description 14
- 239000003550 marker Substances 0.000 description 13
- 101150089778 pyr-4 gene Proteins 0.000 description 13
- 238000012360 testing method Methods 0.000 description 13
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 12
- 101710098247 Exoglucanase 1 Proteins 0.000 description 12
- 241000209219 Hordeum Species 0.000 description 12
- 241001494479 Pecora Species 0.000 description 12
- 125000003275 alpha amino acid group Chemical group 0.000 description 11
- 235000019621 digestibility Nutrition 0.000 description 11
- 239000000047 product Substances 0.000 description 11
- 239000008351 acetate buffer Substances 0.000 description 10
- 235000016709 nutrition Nutrition 0.000 description 10
- 239000013612 plasmid Substances 0.000 description 10
- 238000000746 purification Methods 0.000 description 10
- 239000012876 carrier material Substances 0.000 description 9
- 229940079919 digestives enzyme preparation Drugs 0.000 description 9
- 238000010790 dilution Methods 0.000 description 9
- 239000012895 dilution Substances 0.000 description 9
- 230000007062 hydrolysis Effects 0.000 description 9
- 238000006460 hydrolysis reaction Methods 0.000 description 9
- 239000002243 precursor Substances 0.000 description 9
- 238000003756 stirring Methods 0.000 description 9
- 239000013598 vector Substances 0.000 description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 8
- 101710112457 Exoglucanase Proteins 0.000 description 8
- 241000287828 Gallus gallus Species 0.000 description 8
- 108091028043 Nucleic acid sequence Proteins 0.000 description 8
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 description 8
- 235000005911 diet Nutrition 0.000 description 8
- 230000037213 diet Effects 0.000 description 8
- 239000000523 sample Substances 0.000 description 8
- 235000019786 weight gain Nutrition 0.000 description 8
- 101710130006 Beta-glucanase Proteins 0.000 description 7
- 101710098246 Exoglucanase 2 Proteins 0.000 description 7
- 238000002835 absorbance Methods 0.000 description 7
- 239000003153 chemical reaction reagent Substances 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 230000009466 transformation Effects 0.000 description 7
- SEHFUALWMUWDKS-UHFFFAOYSA-N 5-fluoroorotic acid Chemical compound OC(=O)C=1NC(=O)NC(=O)C=1F SEHFUALWMUWDKS-UHFFFAOYSA-N 0.000 description 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- 108700007698 Genetic Terminator Regions Proteins 0.000 description 6
- 238000003556 assay Methods 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 244000005700 microbiome Species 0.000 description 6
- 108090000765 processed proteins & peptides Proteins 0.000 description 6
- 235000000346 sugar Nutrition 0.000 description 6
- 239000006228 supernatant Substances 0.000 description 6
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 5
- 230000009471 action Effects 0.000 description 5
- 230000037396 body weight Effects 0.000 description 5
- 235000005822 corn Nutrition 0.000 description 5
- 238000000855 fermentation Methods 0.000 description 5
- 230000004151 fermentation Effects 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 150000004804 polysaccharides Chemical class 0.000 description 5
- 241000272517 Anseriformes Species 0.000 description 4
- 108091026890 Coding region Proteins 0.000 description 4
- 229920002472 Starch Polymers 0.000 description 4
- 229960000583 acetic acid Drugs 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 230000015556 catabolic process Effects 0.000 description 4
- 235000013330 chicken meat Nutrition 0.000 description 4
- 238000006731 degradation reaction Methods 0.000 description 4
- 238000012217 deletion Methods 0.000 description 4
- 230000037430 deletion Effects 0.000 description 4
- 239000012362 glacial acetic acid Substances 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 230000028327 secretion Effects 0.000 description 4
- 235000019698 starch Nutrition 0.000 description 4
- 238000006467 substitution reaction Methods 0.000 description 4
- 150000008163 sugars Chemical class 0.000 description 4
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 4
- 229940045145 uridine Drugs 0.000 description 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- 108020004705 Codon Proteins 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 244000068988 Glycine max Species 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 241000282887 Suidae Species 0.000 description 3
- 241001557886 Trichoderma sp. Species 0.000 description 3
- 125000000539 amino acid group Chemical group 0.000 description 3
- 150000004783 arabinoxylans Chemical class 0.000 description 3
- 239000006227 byproduct Substances 0.000 description 3
- 210000002421 cell wall Anatomy 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000003925 fat Substances 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 230000000968 intestinal effect Effects 0.000 description 3
- 238000004255 ion exchange chromatography Methods 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 244000144972 livestock Species 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 229920001542 oligosaccharide Polymers 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 244000144977 poultry Species 0.000 description 3
- 235000013594 poultry meat Nutrition 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 239000007974 sodium acetate buffer Substances 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 230000001131 transforming effect Effects 0.000 description 3
- 230000004584 weight gain Effects 0.000 description 3
- GHCZTIFQWKKGSB-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;phosphoric acid Chemical compound OP(O)(O)=O.OC(=O)CC(O)(C(O)=O)CC(O)=O GHCZTIFQWKKGSB-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000193744 Bacillus amyloliquefaciens Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- 208000023514 Barrett esophagus Diseases 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 2
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 101100295959 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) arcB gene Proteins 0.000 description 2
- 241000286209 Phasianidae Species 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 239000012564 Q sepharose fast flow resin Substances 0.000 description 2
- 108020004511 Recombinant DNA Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000002105 Southern blotting Methods 0.000 description 2
- 108010056079 Subtilisins Proteins 0.000 description 2
- 102000005158 Subtilisins Human genes 0.000 description 2
- 238000005349 anion exchange Methods 0.000 description 2
- 101150008194 argB gene Proteins 0.000 description 2
- 108010047754 beta-Glucosidase Proteins 0.000 description 2
- 102000006995 beta-Glucosidase Human genes 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 101150114858 cbh2 gene Proteins 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000013613 expression plasmid Substances 0.000 description 2
- 239000003337 fertilizer Substances 0.000 description 2
- 235000013312 flour Nutrition 0.000 description 2
- 235000012041 food component Nutrition 0.000 description 2
- 239000004459 forage Substances 0.000 description 2
- 230000005714 functional activity Effects 0.000 description 2
- 230000003301 hydrolyzing effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 101150039489 lysZ gene Proteins 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 108020004999 messenger RNA Proteins 0.000 description 2
- 101150095344 niaD gene Proteins 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 235000019419 proteases Nutrition 0.000 description 2
- 229940116540 protein supplement Drugs 0.000 description 2
- 235000005974 protein supplement Nutrition 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- KUIXZSYWBHSYCN-UHFFFAOYSA-L remazol brilliant blue r Chemical compound [Na+].[Na+].C1=C(S([O-])(=O)=O)C(N)=C2C(=O)C3=CC=CC=C3C(=O)C2=C1NC1=CC=CC(S(=O)(=O)CCOS([O-])(=O)=O)=C1 KUIXZSYWBHSYCN-UHFFFAOYSA-L 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000012086 standard solution Substances 0.000 description 2
- 238000013518 transcription Methods 0.000 description 2
- 230000035897 transcription Effects 0.000 description 2
- 230000002103 transcriptional effect Effects 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- 238000001262 western blot Methods 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- 229920001221 xylan Polymers 0.000 description 2
- WDMUXYQIMRDWRC-UHFFFAOYSA-N 2-hydroxy-3,4-dinitrobenzoic acid Chemical compound OC(=O)C1=CC=C([N+]([O-])=O)C([N+]([O-])=O)=C1O WDMUXYQIMRDWRC-UHFFFAOYSA-N 0.000 description 1
- LWFUFLREGJMOIZ-UHFFFAOYSA-N 3,5-dinitrosalicylic acid Chemical compound OC(=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O LWFUFLREGJMOIZ-UHFFFAOYSA-N 0.000 description 1
- 101000899859 Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) Endoglucanase 1 Proteins 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 241000351920 Aspergillus nidulans Species 0.000 description 1
- 241000228257 Aspergillus sp. Species 0.000 description 1
- 241000193375 Bacillus alcalophilus Species 0.000 description 1
- 241000193422 Bacillus lentus Species 0.000 description 1
- 241000194108 Bacillus licheniformis Species 0.000 description 1
- 241000194110 Bacillus sp. (in: Bacteria) Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 1
- 244000188595 Brassica sinapistrum Species 0.000 description 1
- 102000004031 Carboxy-Lyases Human genes 0.000 description 1
- 108090000489 Carboxy-Lyases Proteins 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 description 1
- 241000193169 Clostridium cellulovorans Species 0.000 description 1
- 241000193464 Clostridium sp. Species 0.000 description 1
- 108010042407 Endonucleases Proteins 0.000 description 1
- 102000004533 Endonucleases Human genes 0.000 description 1
- 108050001049 Extracellular proteins Proteins 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 241000223221 Fusarium oxysporum Species 0.000 description 1
- 241001149959 Fusarium sp. Species 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 101000596741 Homo sapiens Testis-specific protein TEX28 Proteins 0.000 description 1
- 241001480714 Humicola insolens Species 0.000 description 1
- 241001373560 Humicola sp. Species 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- 241001558145 Mucor sp. Species 0.000 description 1
- 241001203365 Myceliophthora sp. Species 0.000 description 1
- 101100032401 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) pyr-4 gene Proteins 0.000 description 1
- 238000000636 Northern blotting Methods 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 241000228168 Penicillium sp. Species 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 241000222385 Phanerochaete Species 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- 241000235403 Rhizomucor miehei Species 0.000 description 1
- 241000282849 Ruminantia Species 0.000 description 1
- 241000193448 Ruminiclostridium thermocellum Species 0.000 description 1
- 241000222482 Schizophyllum sp. Species 0.000 description 1
- 229920002684 Sepharose Polymers 0.000 description 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 101100370749 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) trpC1 gene Proteins 0.000 description 1
- 241000187180 Streptomyces sp. Species 0.000 description 1
- 102100035104 Testis-specific protein TEX28 Human genes 0.000 description 1
- 241000378866 Trichoderma koningii Species 0.000 description 1
- 240000000359 Triticum dicoccon Species 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 238000001042 affinity chromatography Methods 0.000 description 1
- 238000000246 agarose gel electrophoresis Methods 0.000 description 1
- 108010050181 aleurone Proteins 0.000 description 1
- 108010030291 alpha-Galactosidase Proteins 0.000 description 1
- 102000005840 alpha-Galactosidase Human genes 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 229940040526 anhydrous sodium acetate Drugs 0.000 description 1
- 235000019728 animal nutrition Nutrition 0.000 description 1
- 229920000617 arabinoxylan Polymers 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000001588 bifunctional effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000012496 blank sample Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 108010085318 carboxymethylcellulase Proteins 0.000 description 1
- 108020001778 catalytic domains Proteins 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000007398 colorimetric assay Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 101150003727 egl2 gene Proteins 0.000 description 1
- 108010091371 endoglucanase 1 Proteins 0.000 description 1
- 108010091384 endoglucanase 2 Proteins 0.000 description 1
- 108010092450 endoglucanase Z Proteins 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- -1 fcrpC Proteins 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000001502 gel electrophoresis Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 244000144980 herd Species 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012886 linear function Methods 0.000 description 1
- 235000019626 lipase activity Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000000520 microinjection Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 238000001426 native polyacrylamide gel electrophoresis Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 description 1
- KYOBSHFOBAOFBF-XVFCMESISA-N orotidine 5'-phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1C(O)=O KYOBSHFOBAOFBF-XVFCMESISA-N 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 238000009304 pastoral farming Methods 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- LJCNRYVRMXRIQR-OLXYHTOASA-L potassium sodium L-tartrate Chemical compound [Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O LJCNRYVRMXRIQR-OLXYHTOASA-L 0.000 description 1
- 229940074439 potassium sodium tartrate Drugs 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 235000019833 protease Nutrition 0.000 description 1
- 210000001938 protoplast Anatomy 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 235000011006 sodium potassium tartrate Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 101150016309 trpC gene Proteins 0.000 description 1
- 229920000785 ultra high molecular weight polyethylene Polymers 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Plant Pathology (AREA)
- Animal Husbandry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Detergent Compositions (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/169,948 US5861271A (en) | 1993-12-17 | 1993-12-17 | Cellulase enzymes and systems for their expressions |
| PCT/EP1994/004212 WO1995016360A1 (en) | 1993-12-17 | 1994-12-19 | An enzyme feed additive and animal feed including it |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO953218D0 NO953218D0 (no) | 1995-08-16 |
| NO953218L NO953218L (no) | 1995-10-16 |
| NO314562B1 true NO314562B1 (no) | 2003-04-14 |
Family
ID=22617873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19953218A NO314562B1 (no) | 1993-12-17 | 1995-08-16 | Enzymbasert fôradditiv, samt fôr inneholdende dette |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US5861271A (ja) |
| EP (3) | EP1700524B1 (ja) |
| JP (1) | JPH09506514A (ja) |
| CN (1) | CN1093379C (ja) |
| AT (3) | ATE387104T1 (ja) |
| AU (1) | AU685210B2 (ja) |
| CA (2) | CA2178636A1 (ja) |
| DE (3) | DE69435078T2 (ja) |
| DK (2) | DK0684770T3 (ja) |
| ES (1) | ES2160694T3 (ja) |
| FI (2) | FI116965B (ja) |
| HK (1) | HK1097163A1 (ja) |
| NO (1) | NO314562B1 (ja) |
| NZ (1) | NZ278373A (ja) |
| PT (1) | PT684770E (ja) |
| WO (2) | WO1995016782A1 (ja) |
Families Citing this family (252)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6268196B1 (en) | 1993-12-17 | 2001-07-31 | Genencor International, Inc. | Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions |
| US5861271A (en) * | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
| US7005128B1 (en) | 1993-12-17 | 2006-02-28 | Genencor International, Inc. | Enzyme feed additive and animal feed including it |
| FR2715802B1 (fr) * | 1994-02-04 | 1996-03-15 | Rhone Poulenc Nutrition Animal | Utilisation d'enzymes dans l'alimentation des animaux pour réduire les rejets azotés. |
| GB9424661D0 (en) * | 1994-12-07 | 1995-02-01 | Biotal Ltd | Enzymes, microorganisms and their use |
| ATE315083T1 (de) | 1995-03-17 | 2006-02-15 | Novozymes As | Neue endoglukanase |
| US5700686A (en) * | 1995-06-06 | 1997-12-23 | Iogen Corporation | Protease-treated and purified cellulase compositions and methods for reducing backstaining during enzymatic stonewashing |
| EP0850295B2 (en) | 1995-09-08 | 2011-11-30 | Novozymes A/S | Prevention of back-staining in stone washing |
| US5958083A (en) * | 1995-09-08 | 1999-09-28 | Novo Nordisk A/A | Prevention of back-staining in stone washing |
| US6723549B2 (en) | 1995-10-17 | 2004-04-20 | Ab Enzymes Oy | Cellulases, the genes encoding them and uses thereof |
| US6184019B1 (en) | 1995-10-17 | 2001-02-06 | Röhm Enzyme Finland OY | Cellulases, the genes encoding them and uses thereof |
| US6190898B1 (en) * | 1995-10-23 | 2001-02-20 | Genencor International, Inc. | Crystalline cellulase and method for producing same |
| EP0877799A1 (en) * | 1996-01-29 | 1998-11-18 | Novo Nordisk A/S | Process for desizing cellulosic fabric |
| AR005601A1 (es) * | 1996-01-29 | 1999-06-23 | Novozymes As | Proceso para la remocion o blanqueo de suciedad o manchas presentes en telas celulosicas y proceso para el lavado de telas celulosicas manchadas o sucias y composicion detergente |
| US6277596B1 (en) * | 1996-09-13 | 2001-08-21 | Meiji Seika Kaisha, Ltd. | Regulatory sequence of cellulase cbh1 genes originating in trichoderma viride and system for mass-producing proteins or peptides therewith |
| US6451063B1 (en) * | 1996-09-25 | 2002-09-17 | Genencor International, Inc. | Cellulase for use in industrial processes |
| US6017870A (en) * | 1996-10-09 | 2000-01-25 | Genencor International, Inc. | Purified cellulase and method of producing |
| EP0975745B1 (en) * | 1996-10-28 | 2008-02-20 | Novozymes A/S | Extracellular expression of cellulose binding domains (cbd) using bacillus |
| FI964692A0 (fi) * | 1996-11-25 | 1996-11-25 | Primalco Ltd | Foerbaettrad cellulassammansaettning foer bioefterbehandling av textilmaterial som innehaoller cellulosa |
| US5866407A (en) * | 1997-03-18 | 1999-02-02 | Iogen Corporation | Method and enzyme mixture for improved depilling of cotton goods |
| TW409035B (en) | 1997-06-04 | 2000-10-21 | Gist Brocades Bv | Starch-based enzyme granulates |
| ES2234067T5 (es) * | 1997-07-31 | 2009-05-01 | Dsm Ip Assets B.V. | Composicion para mejorar el pan. |
| US6294366B1 (en) * | 1997-09-19 | 2001-09-25 | Clariant Finance (Bvi) Limited | Compositions and methods for treating cellulose containing fabrics using truncated cellulase enzyme compositions |
| US6287839B1 (en) | 1997-11-19 | 2001-09-11 | Genencor International, Inc. | Cellulase producing actinomycetes, cellulase produced therefrom and method of producing same |
| GB9724629D0 (en) * | 1997-11-20 | 1998-01-21 | Genencor Int Bv | Alpha/beta hydrolase-fold enzymes |
| DK1038008T3 (da) * | 1997-12-16 | 2007-03-12 | Genencor Int | Fremgangsmåde til fremstilling af EGIII-lignende enzymer |
| CN101024826B (zh) | 1998-06-10 | 2014-09-03 | 诺沃奇梅兹有限公司 | 新的甘露聚糖酶 |
| US6407046B1 (en) | 1998-09-03 | 2002-06-18 | Genencor International, Inc. | Mutant EGIII cellulase, DNA encoding such EGIII compositions and methods for obtaining same |
| US6268328B1 (en) * | 1998-12-18 | 2001-07-31 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
| US6579841B1 (en) | 1998-12-18 | 2003-06-17 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
| US7977051B2 (en) | 1999-04-10 | 2011-07-12 | Danisco Us Inc. | EGIII-like enzymes, DNA encoding such enzymes and methods for producing such enzymes |
| US7375197B2 (en) * | 2002-01-14 | 2008-05-20 | Midwest Research Institute | Cellobiohydrolase I gene and improved variants |
| US8637293B2 (en) * | 1999-07-13 | 2014-01-28 | Alliance For Sustainable Energy, Llc | Cellobiohydrolase I enzymes |
| DE60045255D1 (de) * | 1999-12-23 | 2010-12-30 | Genencor Int | Cellulase von t. reesei mit verbesserter thermostabilität |
| WO2001072783A2 (en) * | 2000-03-24 | 2001-10-04 | Genencor International, Inc. | Production of secreted proteins by recombinant eukaryotic cells |
| GB0011439D0 (en) * | 2000-05-12 | 2000-06-28 | Novartis Res Found | Cancer diagnosis and assays for screening |
| US6623949B1 (en) | 2000-08-04 | 2003-09-23 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
| JP4557108B2 (ja) * | 2000-08-11 | 2010-10-06 | ライオン株式会社 | キメラ酵素及び洗浄剤組成物 |
| ES2266265T3 (es) * | 2000-09-25 | 2007-03-01 | Iogen Energy Corporation | Metodo para la produccion de glucosa con una mezcla de celulosa que comprende una celulosa modificada. |
| ES2521615T3 (es) | 2001-06-06 | 2014-11-13 | Novozymes A/S | Endo-beta-1,4-glucanasa |
| DE60221266T2 (de) * | 2001-10-26 | 2008-02-14 | Novozymes A/S | Verfahren zur herstellung von esswaren |
| DK1485495T3 (da) * | 2002-03-15 | 2010-11-22 | Iogen Energy Corp | Fremgangsmåde til glucosefremstilling under anvendelse af endoglucanasekerneprotein til forbedret indvinding og genbrug af enzym |
| GB2389584A (en) * | 2002-06-14 | 2003-12-17 | Norsk Hydro As | A fusion protein |
| DK1578943T3 (da) | 2002-08-16 | 2012-01-09 | Danisco Us Inc | Nye variant-Hypocrea jecorina-CBH1-cellulaser |
| SI1627050T1 (sl) * | 2003-04-01 | 2014-01-31 | Danisco Us Inc. | Varianta humicola grisea cbh1.1 |
| EP1618183B1 (en) | 2003-04-29 | 2014-11-19 | Danisco US Inc. | Novel bacillus 029cel cellulase |
| WO2004099370A2 (en) | 2003-04-30 | 2004-11-18 | Genencor International, Inc. | NOVEL BACILLUS mHKcel CELLULASE |
| CN101300335A (zh) | 2003-04-30 | 2008-11-05 | 金克克国际有限公司 | 新颖的杆菌BagCel纤维素酶 |
| ATE478140T1 (de) | 2003-05-02 | 2010-09-15 | Novozymes Inc | Verfahren zur herstellung sezernierter polypeptide |
| WO2005001036A2 (en) | 2003-05-29 | 2005-01-06 | Genencor International, Inc. | Novel trichoderma genes |
| WO2004113551A1 (en) | 2003-06-25 | 2004-12-29 | Novozymes A/S | Process for the hydrolysis of starch |
| WO2005003311A2 (en) | 2003-06-25 | 2005-01-13 | Novozymes A/S | Enzymes for starch processing |
| MXPA06004463A (es) | 2003-10-28 | 2006-06-27 | Novozymes North America Inc | Enzimas hibridas. |
| EP1682655B1 (en) | 2003-10-30 | 2009-09-02 | Novozymes A/S | Carbohydrate-binding modules |
| US7985569B2 (en) | 2003-11-19 | 2011-07-26 | Danisco Us Inc. | Cellulomonas 69B4 serine protease variants |
| BRPI0416797A (pt) | 2003-11-19 | 2007-04-17 | Genencor Int | serina proteases, ácidos nucléicos codificando enzimas de serina e vetores e células hospedeiras incorporando as mesmas |
| CN1875099B (zh) * | 2003-11-21 | 2011-05-04 | 金克克国际有限公司 | 颗粒淀粉水解酶在木霉菌中的表达和从颗粒淀粉底物产生葡萄糖的方法 |
| US20070148741A1 (en) | 2003-12-19 | 2007-06-28 | Novozymes A/S | Mashing process |
| BRPI0509212A (pt) | 2004-03-25 | 2007-08-28 | Genencor Int | proteìna de fusão de celulase e construto de fusão de celulase heterólogo codificando a mesma |
| US8097445B2 (en) | 2004-03-25 | 2012-01-17 | Danisco Us Inc. | Exo-endo cellulase fusion protein |
| DE602005021479D1 (de) * | 2004-04-16 | 2010-07-08 | Ab Enzymes Oy | Verfahren und dna-konstrukte zur erhöhung des produktionsniveaus von kohlenhydrat abbauenden enzymen in filamentösen pilzen |
| US7348172B2 (en) * | 2004-04-16 | 2008-03-25 | Ab Enzymes Oy | Method and DNA constructs for increasing the production level of carbohydrate degrading enzymes in filamentous fungi |
| US7037704B2 (en) * | 2004-05-27 | 2006-05-02 | Genencor International, Inc. | Heterologous expression of an Aspergillus kawachi acid-stable alpha amylase and applications in granular starch hydrolysis |
| US7332319B2 (en) * | 2004-05-27 | 2008-02-19 | Genencor International, Inc. | Heterologous alpha amylase expression in Aspergillus |
| WO2005117756A2 (en) * | 2004-05-27 | 2005-12-15 | Genencor International, Inc. | Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions |
| WO2006069289A2 (en) | 2004-12-22 | 2006-06-29 | Novozymes North America, Inc | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| AR051863A1 (es) | 2004-12-22 | 2007-02-14 | Novozymes As | Enzimas hibridas |
| WO2006074005A2 (en) * | 2004-12-30 | 2006-07-13 | Genencor International, Inc. | Variant hypocrea jecorina cbh2 cellulases |
| JP5087407B2 (ja) | 2004-12-30 | 2012-12-05 | ジェネンコー・インターナショナル・インク | 酸性真菌プロテアーゼ |
| EP2333045B1 (en) * | 2005-04-12 | 2016-11-09 | Danisco US Inc. | Gene inactivated mutants with altered protein production |
| MY145870A (en) * | 2005-12-15 | 2012-05-15 | Lilly Co Eli | Enzymes for reduced immunological stress |
| BRPI0710217A2 (pt) * | 2006-03-30 | 2011-08-02 | Novozymes Inc | polipeptìdeo, polinucleotìdeo, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir o polipeptìdeo, para produzir um mutante a partir de uma célula precursora, para produzir uma proteìna, para produzir um polinucleotìdeo, para degradar ou converter um material celulósico, para produzir uma substáncia e para inibir a expressão de um polinucleotìdeo em uma célula, célula mutante, planta transgênica, parte de planta ou célula de planta, e, molécula de rna de filamento duplo |
| BRPI0713389A2 (pt) | 2006-06-21 | 2012-04-17 | Novozymes North America, Inc. e Novozymes A/S | processo para desengomagem e lavagem combinadas de um tecido engomado, e, composição |
| DK2069512T3 (da) * | 2006-09-22 | 2010-09-20 | Danisco Us Inc Genencor Div | Acetolaktat-syntase fra Trichoderma reesei som selektionsmarkør |
| US9447397B2 (en) | 2006-10-10 | 2016-09-20 | Danisco Us Inc. | Glucoamylase variants with altered properties |
| US8105812B2 (en) * | 2006-12-18 | 2012-01-31 | Danisco Us Inc. | Laccases, compositions and methods of use |
| US20080220498A1 (en) * | 2007-03-06 | 2008-09-11 | Cervin Marguerite A | Variant Buttiauxella sp. phytases having altered properties |
| US8143046B2 (en) | 2007-02-07 | 2012-03-27 | Danisco Us Inc., Genencor Division | Variant Buttiauxella sp. phytases having altered properties |
| CN101636490B (zh) | 2007-03-14 | 2012-05-16 | 丹尼斯科美国公司 | 里氏木霉α-淀粉酶是一种生麦芽糖酶 |
| DK2147104T3 (en) * | 2007-05-21 | 2015-12-14 | Danisco Us Inc | USING A ASPARAGINPROTEASE- (NSP24) SIGNAL SEQUENCE FOR heterologous protein EXPRESSION |
| US8450098B2 (en) * | 2007-05-21 | 2013-05-28 | Danisco Us Inc. | Method for introducing nucleic acids into fungal cells |
| EP2170099B1 (en) * | 2007-06-29 | 2014-11-19 | Kemin Industries (Zhuhai) Co. Ltd. | Enzyme product for ruminants |
| PL2514818T3 (pl) | 2007-10-09 | 2014-11-28 | Danisco Us Inc | Odmiany glukoamylazy |
| US8592194B2 (en) | 2007-10-09 | 2013-11-26 | Danisco Us Inc. | Glucoamylase variants with altered properties |
| US7618801B2 (en) * | 2007-10-30 | 2009-11-17 | Danison US Inc. | Streptomyces protease |
| CN101842479A (zh) * | 2007-11-01 | 2010-09-22 | 丹尼斯科美国公司 | 用于改良宿主细胞内蛋白质生产的信号序列和共表达的分子伴侣 |
| ES2527586T3 (es) | 2007-11-20 | 2015-01-27 | Danisco Us Inc. | Variantes de glucoamilasa con propiedades modificadas |
| SG162265A1 (en) | 2007-12-13 | 2010-07-29 | Danisco Us Inc | Compositions and methods for producing isoprene |
| EP2546338A1 (en) | 2008-01-02 | 2013-01-16 | Danisco US Inc. | A process of obtaining ethanol without glucoamylase using pseudomonas saccharophila g4-amylase and variants thereof |
| NO2254591T3 (ja) | 2008-02-08 | 2017-12-23 | ||
| EP2268806B1 (en) * | 2008-02-11 | 2013-04-10 | Danisco US Inc. | Enzyme with microbial lysis activity from Trichoderma reesei |
| EP2245138A4 (en) | 2008-02-19 | 2011-03-02 | Novozymes As | METHOD FOR STONE WASHING OF TISSUES USING CELLULASE |
| WO2009114380A1 (en) * | 2008-03-07 | 2009-09-17 | Danisco Us Inc., Genencor Division | Expression of catalase in trichoderma |
| US20090253173A1 (en) * | 2008-04-08 | 2009-10-08 | Danisco Us Inc., Genencor Division | Filamentous fungi with inactivated protease genes for altered protein production |
| EP3118309B1 (en) | 2008-04-18 | 2020-09-16 | Danisco US Inc. | Buttiauxella sp. phytase variants |
| US8173410B2 (en) | 2008-04-23 | 2012-05-08 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
| DK2288698T3 (en) | 2008-06-06 | 2017-03-20 | Danisco Us Inc | COMPOSITIONS AND PROCEDURES INCLUDING CELLULASE-VARIABLE VARIETIES FOR CELLULOSE-FREE MATERIALS |
| JP5647976B2 (ja) | 2008-06-06 | 2015-01-07 | ダニスコ・ユーエス・インク | 変異体微生物プロテアーゼを含む組成物及び方法 |
| MY156256A (en) * | 2008-07-02 | 2016-01-29 | Danisco Us Inc | Compositions and methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges |
| WO2010031068A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| CA2737195A1 (en) * | 2008-09-15 | 2010-03-18 | The Goodyear Tire & Rubber Company | Conversion of prenyl derivatives to isoprene |
| SG169640A1 (en) * | 2008-09-15 | 2011-04-29 | Danisco Us Inc | Increased isoprene production using mevalonate kinase and isoprene synthase |
| BRPI0918453A2 (pt) | 2008-09-15 | 2019-12-17 | Danisco Us Inc | sistemas usando cultura de células para a produção de isopreno |
| WO2010031062A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using the archaeal lower mevalonate pathway |
| BRPI0921827A2 (pt) | 2008-11-11 | 2016-09-27 | Danisco Us Inc | composições e métodos compreendendo uma variante de subtilisina |
| EP2647692A3 (en) | 2008-11-11 | 2014-01-22 | The Procter and Gamble Company | Compositions and methods comprising serine protease variants |
| KR20110095260A (ko) | 2008-11-11 | 2011-08-24 | 다니스코 유에스 인크. | 하나 이상의 조합가능 돌연변이를 포함하는 바실러스 서브틸리신 |
| US20100152088A1 (en) | 2008-11-11 | 2010-06-17 | Estell David A | Compositions and methods comprising a subtilisin variant |
| EP2626421B1 (en) | 2008-12-10 | 2014-03-19 | Direvo Industrial Biotechnology GmbH | Improved enzymes for biomass conversion |
| WO2010074999A1 (en) | 2008-12-15 | 2010-07-01 | Danisco Us Inc. | Hybrid alpha-amylases |
| MX2011006779A (es) | 2008-12-24 | 2011-08-03 | Danisco Us Inc | Lacasas y metodos de uso de las mismas a temperatura baja. |
| CA2748887A1 (en) | 2008-12-30 | 2010-07-08 | Danisco Us Inc. | Methods of producing isoprene and a co-product |
| KR20110139206A (ko) | 2009-03-03 | 2011-12-28 | 다니스코 유에스 인크. | 효소적으로 생성된 과산을 사용한 염료의 산화 탈색 - 방법, 조성물 및 파트들의 키트 |
| WO2010124146A2 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| DK3591046T3 (da) | 2009-05-19 | 2021-07-26 | Dupont Nutrition Biosci Aps | Amylasepolypeptide |
| CN104862293A (zh) | 2009-06-03 | 2015-08-26 | 丹尼斯科美国公司 | 具有改善的表达、活性和/或稳定性的纤维素酶变体,及其用途 |
| TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
| TW201412988A (zh) * | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| TW201120213A (en) | 2009-06-17 | 2011-06-16 | Danisco Us Inc | Polymerization of isoprene from renewable resources |
| PE20121504A1 (es) | 2009-08-19 | 2012-11-05 | Dupont Nutrition Biosci Aps | Variantes de glucoamilasa |
| CN102712915B (zh) | 2009-08-19 | 2014-12-10 | 丹尼斯科美国公司 | 具有改良比活和/或热稳定性的葡糖淀粉酶的组合变体 |
| MX2011008848A (es) | 2009-08-27 | 2011-09-29 | Danisco Us Inc | Modificacion de color y desgaste textil, combinados. |
| WO2011072099A2 (en) | 2009-12-09 | 2011-06-16 | Danisco Us Inc. | Compositions and methods comprising protease variants |
| US20120258900A1 (en) | 2009-12-21 | 2012-10-11 | Danisco Us Inc. | Detergent compositions containing bacillus subtilis lipase and methods of use thereof |
| MX2012007168A (es) | 2009-12-21 | 2012-07-23 | Danisco Us Inc | Composiciones de detergentes que contienen lipasa thermobifida fusca y metodos de uso de esta. |
| WO2011084417A1 (en) | 2009-12-21 | 2011-07-14 | Danisco Us Inc. | Detergent compositions containing geobacillus stearothermophilus lipase and methods of use thereof |
| US9107440B2 (en) | 2010-03-29 | 2015-08-18 | Dupont Nutrition Biosciences Aps | Polypeptides having transgalactosylating activity |
| WO2011130222A2 (en) | 2010-04-15 | 2011-10-20 | Danisco Us Inc. | Compositions and methods comprising variant proteases |
| CN108410585A (zh) | 2010-05-06 | 2018-08-17 | 宝洁公司 | 具有蛋白酶变体的消费品 |
| WO2011150157A2 (en) | 2010-05-28 | 2011-12-01 | Danisco Us Inc. | Detergent compositions containing streptomyces griseus lipase and methods of use thereof |
| US8933282B2 (en) | 2010-06-17 | 2015-01-13 | Danisco Us Inc. | Fuel compositions comprising isoprene derivatives |
| US20120034659A1 (en) | 2010-08-06 | 2012-02-09 | Danisco Us Inc. | NEUTRAL pH SACCHARIFICATION AND FERMENTATION |
| US20120045812A1 (en) | 2010-08-06 | 2012-02-23 | Danisco Us Inc. | PRODUCTION OF ISOPRENE UNDER NEUTRAL pH CONDITIONS |
| JP5810489B2 (ja) * | 2010-08-20 | 2015-11-11 | 株式会社豊田中央研究所 | セルラーゼ活性を有するタンパク質及びその利用 |
| EP2608682B1 (en) | 2010-08-24 | 2017-12-13 | Danisco US Inc. | Method of making a snack bar comprising a low temperature rice protein concentrate |
| JP5707494B2 (ja) * | 2010-08-25 | 2015-04-30 | ダニスコ・ユーエス・インク | 粘性の表現型を変化させた糸状菌 |
| CN103189564A (zh) | 2010-10-18 | 2013-07-03 | 丹尼斯科美国公司 | 使用漆酶体系对染色织物进行局部颜色修改 |
| CN103443271A (zh) | 2010-10-27 | 2013-12-11 | 丹尼斯科美国公司 | 用于增加异戊二烯产量的异戊二烯合酶变体 |
| WO2012088462A1 (en) | 2010-12-22 | 2012-06-28 | Danisco Us Inc. | Compositions and methods for improved isoprene production using two types of ispg enzymes |
| US8691541B2 (en) | 2010-12-22 | 2014-04-08 | Danisco Us Inc. | Biological production of pentose sugars using recombinant cells |
| BR112013016491A2 (pt) | 2010-12-30 | 2018-05-22 | Novozymes As | método para tratamento de têxtil |
| GB201102857D0 (en) * | 2011-02-18 | 2011-04-06 | Danisco | Feed additive composition |
| GB201102865D0 (en) * | 2011-02-18 | 2011-04-06 | Danisco | Feed additive composition |
| CN103459594A (zh) | 2011-04-06 | 2013-12-18 | 丹尼斯科美国公司 | 具有提高的表达和/或活性的漆酶变体 |
| CN103649308A (zh) * | 2011-04-28 | 2014-03-19 | 诺维信股份有限公司 | 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸 |
| EP2702072A1 (en) | 2011-04-29 | 2014-03-05 | Danisco US Inc. | Detergent compositions containing bacillus agaradhaerens mannanase and methods of use thereof |
| EP2712363A1 (en) | 2011-04-29 | 2014-04-02 | Danisco US Inc. | Detergent compositions containing geobacillus tepidamans mannanase and methods of use thereof |
| CN103732756A (zh) | 2011-04-29 | 2014-04-16 | 丹尼斯科美国公司 | 用于高密度葡萄糖浆的淀粉液化和糖化的单pH工艺 |
| BR112013026675A2 (pt) | 2011-04-29 | 2016-11-29 | Danisco Us Inc | composições detergentes contendo mananase de bacillus sp., e métodos de uso das mesmas |
| CN106065381B (zh) | 2011-05-05 | 2019-07-26 | 宝洁公司 | 包含丝氨酸蛋白酶变体的组合物和方法 |
| CN103764823B (zh) | 2011-05-05 | 2018-05-11 | 丹尼斯科美国公司 | 包含丝氨酸蛋白酶变体的组合物和方法 |
| US8951764B2 (en) | 2011-08-05 | 2015-02-10 | Danisco Us Inc. | Production of isoprenoids under neutral pH conditions |
| US20140187468A1 (en) | 2011-08-31 | 2014-07-03 | Danisco Us Inc. | Compositions and Methods Comprising a Lipolytic Enzyme Variant |
| WO2013067026A1 (en) | 2011-10-31 | 2013-05-10 | Bp Corporation North America Inc. | Use of plant promoters in filamentous fungi |
| US20130109055A1 (en) | 2011-10-31 | 2013-05-02 | Bp Corporation North America Inc. | Use of mammalian promoters in filamentous fungi |
| CN104024407A (zh) | 2011-12-22 | 2014-09-03 | 丹尼斯科美国公司 | 包含脂解酶变体的组合物和方法 |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
| DK2859098T3 (en) | 2012-06-08 | 2017-12-11 | Dupont Nutrition Biosci Aps | POLYPEPTIDES WITH TRANSGALACTOSYLATION ACTIVITY |
| MX2015002099A (es) | 2012-08-22 | 2015-05-11 | Dupont Nutrition Biosci Aps | Variantes que tienen actividad glucoamilasa. |
| US10005988B2 (en) | 2012-10-05 | 2018-06-26 | Novozymes A/S | Reducing adhesion of bacteria to a surface or releasing bacteria from a surface to which they adhere using endo-beta-A,4-glucanases |
| MX361862B (es) | 2012-10-12 | 2018-12-18 | Danisco Us Inc | Composiciones y métodos que comprenden variante de enzima lipolítica. |
| US20160060611A1 (en) | 2012-11-05 | 2016-03-03 | Danisco Us Inc. | Compositions and methods comprising thermolysin protease variants |
| CA2892786A1 (en) | 2012-12-12 | 2014-06-19 | Danisco Us Inc. | Variants of cellobiohydrolases |
| US20150344858A1 (en) | 2012-12-19 | 2015-12-03 | Danisco Us Inc. | Novel mannanase, compositions and methods of use thereof |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| WO2014145768A2 (en) | 2013-03-15 | 2014-09-18 | Bp Corporation North America Inc. | Use of non-fungal 5' utrs in filamentous fungi |
| EP3004342B1 (en) | 2013-05-29 | 2023-01-11 | Danisco US Inc. | Novel metalloproteases |
| EP3636662B1 (en) | 2013-05-29 | 2022-07-13 | Danisco US Inc. | Novel metalloproteases |
| EP3004341B1 (en) | 2013-05-29 | 2017-08-30 | Danisco US Inc. | Novel metalloproteases |
| WO2014194032A1 (en) | 2013-05-29 | 2014-12-04 | Danisco Us Inc. | Novel metalloproteases |
| ES2956266T3 (es) | 2013-07-19 | 2023-12-18 | Danisco Us Inc | Composiciones y procedimientos que comprenden una variante de enzima lipolítica |
| BR112016002067A2 (pt) | 2013-07-29 | 2017-08-29 | Danisco Us Inc | Variantes de enzimas |
| BR112016005286A2 (pt) | 2013-09-12 | 2017-09-12 | Danisco Us Inc | composições e métodos compreendendo variantes de protease do clado lg12 |
| WO2015049370A1 (en) | 2013-10-03 | 2015-04-09 | Novozymes A/S | Detergent composition and use of detergent composition |
| CN103529024B (zh) * | 2013-10-16 | 2015-12-23 | 天津博菲德科技有限公司 | 果胶酶在饲料原料中的最适添加量配方 |
| MX2016007636A (es) | 2013-12-11 | 2016-10-13 | Dupont Nutrition Biosci Aps | Metodo para preparar un producto lacteo que tiene un contenido estable de galactooligosacarido(s). |
| DK3080262T3 (da) | 2013-12-13 | 2019-05-06 | Danisco Us Inc | Serinproteaser af bacillus-arter |
| DK3553173T3 (da) | 2013-12-13 | 2021-08-23 | Danisco Us Inc | Serinproteaser af bacillus gibsonii-clade |
| RU2546889C1 (ru) * | 2013-12-16 | 2015-04-10 | Государственное научное учреждение Всероссийский научно-исследовательский и технологический институт птицеводства Россельхозакадемии | Способ кормления цыплят-бройлеров и кур-несушек |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| MX2016012044A (es) | 2014-03-21 | 2017-06-29 | Danisco Us Inc | Serina proteasas de especies de bacillus. |
| EP3207129B1 (en) | 2014-10-17 | 2019-11-20 | Danisco US Inc. | Serine proteases of bacillus species |
| WO2016069552A1 (en) | 2014-10-27 | 2016-05-06 | Danisco Us Inc. | Serine proteases |
| EP3224357A1 (en) | 2014-10-27 | 2017-10-04 | Danisco US Inc. | Serine proteases of bacillus species |
| US20170335306A1 (en) | 2014-10-27 | 2017-11-23 | Danisco Us Inc. | Serine proteases |
| EP3550017B1 (en) | 2014-10-27 | 2021-07-14 | Danisco US Inc. | Serine proteases |
| EP3212783B1 (en) | 2014-10-27 | 2024-06-26 | Danisco US Inc. | Serine proteases |
| EP3214942B1 (en) | 2014-11-07 | 2021-02-24 | DuPont Nutrition Biosciences ApS | Recombinant host cell expressing beta-galactosidase and/or transgalactosylating activity deficient in mannanase, cellulase and pectinase. |
| AU2015366380B2 (en) | 2014-12-19 | 2021-07-22 | Novozymes A/S | Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity |
| RU2580154C1 (ru) * | 2014-12-30 | 2016-04-10 | Федеральное государственное бюджетное научное учреждение "Северо-Кавказский научно-исследовательский институт животноводства" | Способ выращивания молодняка свиней и мясной птицы |
| EP3268471B1 (en) | 2015-03-12 | 2019-08-28 | Danisco US Inc. | Compositions and methods comprising lg12-clade protease variants |
| WO2016183509A1 (en) | 2015-05-13 | 2016-11-17 | Danisco Us Inc. | AprL-CLADE PROTEASE VARIANTS AND USES THEREOF |
| US20180142228A1 (en) | 2015-05-22 | 2018-05-24 | Dupont Nutrition Biosciences Aps | Aldc production methods |
| EP3298138B1 (en) | 2015-05-22 | 2022-08-10 | DuPont Nutrition Biosciences ApS | Acetolactate decarboxylase |
| WO2016201040A1 (en) | 2015-06-09 | 2016-12-15 | Danisco Us Inc. | Water-triggered enzyme suspension |
| WO2016201069A1 (en) | 2015-06-09 | 2016-12-15 | Danisco Us Inc | Low-density enzyme-containing particles |
| FI3307427T3 (fi) | 2015-06-09 | 2023-11-09 | Danisco Us Inc | Osmoottiset puhkeavat kapselit |
| US11499146B2 (en) | 2015-06-17 | 2022-11-15 | Danisco Us Inc. | Bacillus gibsonii-clade serine proteases |
| EP3344282B8 (en) | 2015-09-02 | 2020-12-23 | DuPont Nutrition Biosciences ApS | Glycoside hydrolases and their use in preventing and/or treating a pathogenic infection in an animal |
| EP4141113A1 (en) | 2015-11-05 | 2023-03-01 | Danisco US Inc | Paenibacillus sp. mannanases |
| WO2017079756A1 (en) | 2015-11-05 | 2017-05-11 | Danisco Us Inc | Paenibacillus and bacillus spp. mannanases |
| EP3380628B1 (en) | 2015-11-26 | 2022-11-02 | Novozymes A/S | Milling process |
| EP3390625B1 (en) | 2015-12-18 | 2023-09-06 | Danisco US Inc. | Polypeptides with endoglucanase activity and uses thereof |
| TWI553121B (zh) * | 2015-12-23 | 2016-10-11 | 基酵生物科技股份有限公司 | 提升耐溫性的纖維素酶 |
| JP2019518440A (ja) | 2016-05-03 | 2019-07-04 | ダニスコ・ユーエス・インク | プロテアーゼ変異体およびその使用 |
| WO2017192300A1 (en) | 2016-05-05 | 2017-11-09 | Danisco Us Inc | Protease variants and uses thereof |
| CN109477112B (zh) | 2016-05-31 | 2024-09-06 | 丹尼斯科美国公司 | 蛋白酶变体及其用途 |
| JP7152319B2 (ja) | 2016-06-17 | 2022-10-12 | ダニスコ・ユーエス・インク | プロテアーゼ変異体およびその使用 |
| CN109642226A (zh) | 2016-06-30 | 2019-04-16 | 丹尼斯科美国公司 | 天冬氨酸蛋白酶 |
| CA3037083A1 (en) | 2016-09-16 | 2018-03-22 | Dupont Nutrition Biosciences Aps | Acetolactate decarboxylase variants having improved specific activity |
| RU2763378C2 (ru) | 2016-09-23 | 2021-12-28 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | ПРИМЕНЕНИЕ АКТИВНЫХ ПРИ НИЗКОМ ЗНАЧЕНИИ pH АЛЬФА-1,4/1,6-ГЛИКОЗИДГИДРОЛАЗ В КАЧЕСТВЕ КОРМОВОЙ ДОБАВКИ ДЛЯ ЖВАЧНЫХ ЖИВОТНЫХ ДЛЯ УЛУЧШЕНИЯ ПЕРЕВАРИВАНИЯ КРАХМАЛА |
| EP3535365A2 (en) | 2016-11-07 | 2019-09-11 | Danisco US Inc. | Laundry detergent composition |
| WO2018093752A1 (en) | 2016-11-15 | 2018-05-24 | Danisco Us Inc. | Filamentous fungi with improved protein production |
| US11180786B2 (en) | 2016-11-25 | 2021-11-23 | Novozymes A/S | GH10 xylanase, GH62 arabinofuranosidase, milling process and other application |
| US11946081B2 (en) | 2016-12-21 | 2024-04-02 | Danisco Us Inc. | Bacillus gibsonii-clade serine proteases |
| US20200392477A1 (en) | 2016-12-21 | 2020-12-17 | Danisco Us Inc. | Protease variants and uses thereof |
| BR112019018381A2 (pt) | 2017-03-06 | 2020-04-07 | Dupont Nutrition Biosci Aps | fucosidases fúngicas e seu uso na prevenção e/ou no tratamento de uma infecção patogênica em um animal |
| CN110621778A (zh) | 2017-03-15 | 2019-12-27 | 丹尼斯科美国公司 | 胰蛋白酶样丝氨酸蛋白酶及其用途 |
| US20200040283A1 (en) | 2017-03-31 | 2020-02-06 | Danisco Us Inc | Delayed release enzyme formulations for bleach-containing detergents |
| EP3645696A1 (en) | 2017-06-30 | 2020-05-06 | Danisco US Inc. | Low-agglomeration, enzyme-containing particles |
| CN111373039A (zh) | 2017-11-29 | 2020-07-03 | 丹尼斯科美国公司 | 具有改善的稳定性的枯草杆菌蛋白酶变体 |
| BR112020012584A2 (pt) | 2017-12-21 | 2020-11-24 | Danisco Us Inc. | grânulos fundidos a quente contendo enzima que compreendem um dessecante termotolerante |
| BR112020016068A2 (pt) | 2018-02-08 | 2020-12-08 | Danisco Us Inc. | Partículas cera termicamente resistente matriz para encapsulamento de enzima |
| WO2019197318A1 (en) | 2018-04-09 | 2019-10-17 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| US20210363470A1 (en) | 2018-06-19 | 2021-11-25 | Danisco Us Inc | Subtilisin variants |
| WO2019245704A1 (en) | 2018-06-19 | 2019-12-26 | Danisco Us Inc | Subtilisin variants |
| EP3833731A1 (en) | 2018-08-30 | 2021-06-16 | Danisco US Inc. | Compositions comprising a lipolytic enzyme variant and methods of use thereof |
| US20210189295A1 (en) | 2018-08-30 | 2021-06-24 | Danisco Us Inc | Enzyme-containing granules |
| WO2020068486A1 (en) | 2018-09-27 | 2020-04-02 | Danisco Us Inc | Compositions for medical instrument cleaning |
| US11339516B2 (en) * | 2018-09-27 | 2022-05-24 | Sanko Tekstil Isletmeleri San. Ve Tic. A.S. | Dyed fabric finishing process |
| EP3887515A1 (en) | 2018-11-28 | 2021-10-06 | Danisco US Inc. | Subtilisin variants having improved stability |
| EP3976776A1 (en) | 2019-05-24 | 2022-04-06 | Danisco US Inc. | Subtilisin variants and methods of use |
| WO2020247582A1 (en) | 2019-06-06 | 2020-12-10 | Danisco Us Inc | Methods and compositions for cleaning |
| US20230049452A1 (en) | 2020-01-13 | 2023-02-16 | Danisco Us Inc | Compositions comprising a lipolytic enzyme variant and methods of use thereof |
| US11920290B2 (en) | 2020-01-14 | 2024-03-05 | Sanko Tekstil Isletmeleri San. Ve Tic A.S. | Process for dyeing textiles and enzymes used therein |
| CN116323935A (zh) | 2020-08-27 | 2023-06-23 | 丹尼斯科美国公司 | 用于清洁的酶和酶组合物 |
| US20240117275A1 (en) | 2021-01-29 | 2024-04-11 | Danisco Us Inc. | Compositions for cleaning and methods related thereto |
| WO2023278297A1 (en) | 2021-06-30 | 2023-01-05 | Danisco Us Inc | Variant lipases and uses thereof |
| EP4396320A2 (en) | 2021-09-03 | 2024-07-10 | Danisco US Inc. | Laundry compositions for cleaning |
| EP4402258A2 (en) | 2021-09-13 | 2024-07-24 | Danisco US Inc. | Bioactive-containing granules |
| EP4448750A2 (en) | 2021-12-16 | 2024-10-23 | Danisco US Inc. | Subtilisin variants and uses thereof |
| WO2023114939A2 (en) | 2021-12-16 | 2023-06-22 | Danisco Us Inc. | Subtilisin variants and methods of use |
| CN118679251A (zh) | 2021-12-16 | 2024-09-20 | 丹尼斯科美国公司 | 枯草杆菌蛋白酶变体和使用方法 |
| WO2023168234A1 (en) | 2022-03-01 | 2023-09-07 | Danisco Us Inc. | Enzymes and enzyme compositions for cleaning |
| WO2023250301A1 (en) | 2022-06-21 | 2023-12-28 | Danisco Us Inc. | Methods and compositions for cleaning comprising a polypeptide having thermolysin activity |
| WO2024050339A1 (en) | 2022-09-02 | 2024-03-07 | Danisco Us Inc. | Mannanase variants and methods of use |
| WO2024050343A1 (en) | 2022-09-02 | 2024-03-07 | Danisco Us Inc. | Subtilisin variants and methods related thereto |
| WO2024050346A1 (en) | 2022-09-02 | 2024-03-07 | Danisco Us Inc. | Detergent compositions and methods related thereto |
| WO2024064653A1 (en) | 2022-09-20 | 2024-03-28 | Dupont Nutrition Biosciences Aps | Variant anti-viral polypeptides |
| WO2024102698A1 (en) | 2022-11-09 | 2024-05-16 | Danisco Us Inc. | Subtilisin variants and methods of use |
| WO2024163584A1 (en) | 2023-02-01 | 2024-08-08 | Danisco Us Inc. | Subtilisin variants and methods of use |
| WO2024186819A1 (en) | 2023-03-06 | 2024-09-12 | Danisco Us Inc. | Subtilisin variants and methods of use |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1338400C (en) * | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
| FR2555603B1 (fr) * | 1983-11-29 | 1986-10-03 | Inst Francais Du Petrole | Procede de production d'enzymes cellulolytiques |
| FI841500A0 (fi) * | 1984-04-13 | 1984-04-13 | Valtion Teknillinen | Foerfarande foer uppbygnande av cellulolytiska jaeststammar. |
| US5298405A (en) * | 1986-04-30 | 1994-03-29 | Alko Limited | Enzyme preparations with recombinantly-altered cellulose profiles and methods for their production |
| US5137819A (en) * | 1988-07-08 | 1992-08-11 | University Of British Columbia | Cellulose binding fusion proteins for immobilization and purification of polypeptides |
| US5340731A (en) * | 1988-07-08 | 1994-08-23 | University Of British Columbia | Method of preparing a B-1,4 glycan matrix containing a bound fusion protein |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| AU638695B2 (en) * | 1989-02-16 | 1993-07-08 | Akademie Der Wissenschaften Der Ddr | A thermostable (1,3-1,4)-beta-glucanase |
| US5536655A (en) * | 1989-09-26 | 1996-07-16 | Midwest Research Institute | Gene coding for the E1 endoglucanase |
| DK494089D0 (ja) * | 1989-10-06 | 1989-10-06 | Novo Nordisk As | |
| DK16490D0 (da) * | 1990-01-19 | 1990-01-19 | Novo Nordisk As | Enzym |
| DK115890D0 (da) * | 1990-05-09 | 1990-05-09 | Novo Nordisk As | Enzym |
| US5475101A (en) * | 1990-10-05 | 1995-12-12 | Genencor International, Inc. | DNA sequence encoding endoglucanase III cellulase |
| US5290474A (en) * | 1990-10-05 | 1994-03-01 | Genencor International, Inc. | Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp |
| US5650322A (en) * | 1990-10-05 | 1997-07-22 | Genencor International, Inc. | Methods for stonewashing fabrics using endoglucanases |
| DK0551386T3 (da) * | 1990-10-05 | 2004-05-10 | Genencor Int | Fremgangsmåde til behandling af bomuldsholdige stoffer med cellulase |
| WO1993005226A1 (en) * | 1991-08-29 | 1993-03-18 | University Of British Columbia | Method for modification of polysaccharide fibres |
| ES2131518T3 (es) * | 1991-12-23 | 1999-08-01 | Dsm Nv | Sistema de expresion eucariota. |
| LT3208B (en) * | 1992-04-10 | 1995-03-27 | Ssv Dev Oy | Enzyme products for use in the improvement of feed value and conservation of fibrous crops |
| US5861271A (en) * | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
-
1993
- 1993-12-17 US US08/169,948 patent/US5861271A/en not_active Expired - Lifetime
-
1994
- 1994-12-19 EP EP06009062A patent/EP1700524B1/en not_active Revoked
- 1994-12-19 DK DK95905079T patent/DK0684770T3/da active
- 1994-12-19 US US08/507,362 patent/US6562340B1/en not_active Expired - Lifetime
- 1994-12-19 AT AT06009062T patent/ATE387104T1/de active
- 1994-12-19 AT AT95905079T patent/ATE203373T1/de not_active IP Right Cessation
- 1994-12-19 AU AU13836/95A patent/AU685210B2/en not_active Ceased
- 1994-12-19 PT PT95905079T patent/PT684770E/pt unknown
- 1994-12-19 DE DE69435078T patent/DE69435078T2/de not_active Expired - Lifetime
- 1994-12-19 EP EP95904857A patent/EP0733115B1/en not_active Expired - Lifetime
- 1994-12-19 DK DK95904857T patent/DK0733115T3/da active
- 1994-12-19 WO PCT/US1994/014163 patent/WO1995016782A1/en active IP Right Grant
- 1994-12-19 CA CA002178636A patent/CA2178636A1/en not_active Abandoned
- 1994-12-19 DE DE69434759T patent/DE69434759T2/de not_active Expired - Lifetime
- 1994-12-19 JP JP7516853A patent/JPH09506514A/ja active Pending
- 1994-12-19 EP EP95905079A patent/EP0684770B1/en not_active Expired - Lifetime
- 1994-12-19 DE DE69427812T patent/DE69427812T2/de not_active Expired - Lifetime
- 1994-12-19 ES ES95905079T patent/ES2160694T3/es not_active Expired - Lifetime
- 1994-12-19 NZ NZ278373A patent/NZ278373A/en unknown
- 1994-12-19 AT AT95904857T patent/ATE329039T1/de not_active IP Right Cessation
- 1994-12-19 CN CN94191216A patent/CN1093379C/zh not_active Expired - Fee Related
- 1994-12-19 CA CA002156066A patent/CA2156066C/en not_active Expired - Lifetime
- 1994-12-19 WO PCT/EP1994/004212 patent/WO1995016360A1/en active IP Right Grant
-
1995
- 1995-05-24 US US08/448,873 patent/US5874276A/en not_active Expired - Lifetime
- 1995-08-16 FI FI953867A patent/FI116965B/fi not_active IP Right Cessation
- 1995-08-16 NO NO19953218A patent/NO314562B1/no not_active IP Right Cessation
-
1996
- 1996-06-12 FI FI962444A patent/FI119695B/fi not_active IP Right Cessation
-
2007
- 2007-03-13 HK HK07102743A patent/HK1097163A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0684770B1 (en) | An enzyme feed additive and animal feed including it | |
| US8715647B2 (en) | Enzyme feed additive and animal feed including it | |
| AU692596B2 (en) | An enzyme feed additive and animal feed including it | |
| Paloheimo et al. | Xylanases and cellulases as feed additives. | |
| RU2261910C2 (ru) | ШТАММ Penicillium funiculosum, ПРОДУЦИРУЮЩИИЙ КОМПЛЕКС ФЕРМЕНТОВ - ЦЕЛЛЮЛАЗУ, ЭНДО-1,4-β-КСИЛАНАЗУ, ЦЕЛЛОБИОГИДРОЛАЗУ, β-ГЛЮКОЗИДАЗУ, ЭНДО-1,3(4)- β-ГЛЮКАНАЗУ, ФЕРУЛОИЛ-ЭСТЕРАЗУ, ЖИДКАЯ КОРМОВАЯ ДОБАВКА И СУХОЙ КОРМ ДЛЯ СЕЛЬСКОХОЗЯЙСТВЕННЫХ ЖИВОТНЫХ | |
| EP2857490B1 (en) | Novel Mannanase Variants | |
| JP6522010B2 (ja) | タンパク質 | |
| WO2001042433A2 (en) | Talaromyces emersonii xylanase | |
| CN106103707B (zh) | 使用木聚糖酶改善发酵过程副产物的方法 | |
| EP4019629A1 (en) | Xylanase variants | |
| Wang et al. | Characterization of a New 1, 3-1, 4-β-Glucanase Gene |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |