MY123354A - 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives - Google Patents

4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Info

Publication number
MY123354A
MY123354A MYPI98002575A MYPI9802575A MY123354A MY 123354 A MY123354 A MY 123354A MY PI98002575 A MYPI98002575 A MY PI98002575A MY PI9802575 A MYPI9802575 A MY PI9802575A MY 123354 A MY123354 A MY 123354A
Authority
MY
Malaysia
Prior art keywords
formula
compounds
relates
homoerythromycin
deoxo
Prior art date
Application number
MYPI98002575A
Other languages
English (en)
Inventor
Brian Scott Bronk
Michael Anthony Letavic
Takushi Kaneko
Bingwei Vera Yang
Edward Alan Glazer
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY123354(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MY123354A publication Critical patent/MY123354A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MYPI98002575A 1997-06-11 1998-06-09 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives MY123354A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11

Publications (1)

Publication Number Publication Date
MY123354A true MY123354A (en) 2006-05-31

Family

ID=21959336

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI98002575A MY123354A (en) 1997-06-11 1998-06-09 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Country Status (49)

Country Link
US (4) US6420536B1 (enExample)
EP (1) EP0988310B9 (enExample)
JP (2) JP3315704B2 (enExample)
KR (1) KR100396168B1 (enExample)
CN (4) CN1793155B (enExample)
AP (1) AP1231A (enExample)
AR (1) AR013086A1 (enExample)
AT (1) ATE251173T1 (enExample)
AU (1) AU749816B2 (enExample)
BG (1) BG64391B1 (enExample)
BR (1) BRPI9810519B8 (enExample)
CA (1) CA2293823C (enExample)
CO (1) CO4950611A1 (enExample)
CZ (1) CZ298556B6 (enExample)
DE (2) DE122004000018I2 (enExample)
DK (1) DK0988310T3 (enExample)
DZ (1) DZ2514A1 (enExample)
EA (1) EA002441B1 (enExample)
EG (1) EG24081A (enExample)
ES (1) ES2205487T3 (enExample)
FR (1) FR04C0013I2 (enExample)
GT (1) GT199800077A (enExample)
HN (1) HN1998000086A (enExample)
HR (1) HRP980314B1 (enExample)
HU (2) HU228005B1 (enExample)
ID (1) ID22992A (enExample)
IL (1) IL132809A0 (enExample)
IS (1) IS1998B (enExample)
LU (1) LU91076I9 (enExample)
MA (1) MA24564A1 (enExample)
ME (1) ME00876B (enExample)
MY (1) MY123354A (enExample)
NL (1) NL300150I2 (enExample)
NO (1) NO316911B1 (enExample)
NZ (2) NZ514871A (enExample)
OA (1) OA11224A (enExample)
PA (1) PA8452201A1 (enExample)
PE (1) PE79699A1 (enExample)
PL (1) PL191601B1 (enExample)
PT (1) PT988310E (enExample)
RS (1) RS49675B (enExample)
SI (1) SI0988310T1 (enExample)
SK (1) SK284171B6 (enExample)
TN (1) TNSN98082A1 (enExample)
TW (1) TW472060B (enExample)
UA (1) UA67744C2 (enExample)
UY (1) UY25040A1 (enExample)
WO (1) WO1998056802A1 (enExample)
ZA (1) ZA985017B (enExample)

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AU2002317415A1 (en) * 2001-08-01 2003-02-17 Pfizer Products Inc. Azalide antibiotic compositions
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US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
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US7767797B1 (en) * 2004-09-30 2010-08-03 Synovo Gmbh Macrocyclic compounds and methods of use thereof
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
US20080227730A1 (en) * 2005-01-14 2008-09-18 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9A-Carbamoyl and Thiocarbamoyl Azalides With Antimalarial Activity
WO2009055557A1 (en) * 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
DK2358379T3 (en) 2008-10-24 2016-03-07 Cempra Pharmaceuticals Inc BIOFORSVAR USING TRIAZOLHOLDIGE macrolides
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
JP5711352B2 (ja) 2010-03-22 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライドの結晶形、およびその使用
WO2011146829A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
CN103080121B (zh) * 2010-09-20 2015-11-25 瑞士诺华动物保健有限公司 用于制备在二脱氧甲基己糖环的C-4”处被环氧基团修饰的9-脱氧-9a-氮杂-9a-高红霉素A的新方法
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CN102993250B (zh) * 2011-07-06 2016-02-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
EP3027634B1 (en) * 2013-07-31 2018-03-21 Farma GRS, d.o.o. Process for preparation of tulathromycin
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普（天津）生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
FR3048612B1 (fr) * 2016-03-14 2020-10-02 Septeos Tulathromycine potentialisee
CN106046077B (zh) * 2016-08-04 2019-07-26 湖北美天生物科技股份有限公司 一种泰拉霉素a的合成方法
CN108003207B (zh) 2017-12-19 2019-05-10 海门慧聚药业有限公司 制备泰拉霉素的方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法

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Also Published As

Publication number Publication date
BRPI9810519A (pt) 2000-09-19
ID22992A (id) 1999-12-23
CN1793155A (zh) 2006-06-28
CA2293823C (en) 2004-02-17
CN1566129A (zh) 2005-01-19
JP2002316933A (ja) 2002-10-31
BRPI9810519B1 (pt) 2012-02-22
AR013086A1 (es) 2000-12-13
PE79699A1 (es) 1999-08-25
HUP0002209A2 (hu) 2000-12-28
GT199800077A (es) 1999-12-02
HUS1200028I1 (hu) 2016-08-29
HK1088014A1 (zh) 2006-10-27
FR04C0013I2 (enExample) 2005-10-21
CO4950611A1 (es) 2000-09-01
FR04C0013I1 (enExample) 2004-06-11
HK1028048A1 (en) 2001-02-02
CN1793155B (zh) 2010-05-12
EG24081A (en) 2008-05-11
CZ442199A3 (cs) 2000-07-12
PT988310E (pt) 2003-12-31
NZ500660A (en) 2002-03-01
IS5252A (is) 1999-11-16
JP2000514098A (ja) 2000-10-24
HU228005B1 (en) 2012-08-28
UY25040A1 (es) 2000-09-29
EA002441B1 (ru) 2002-04-25
ZA985017B (en) 1999-12-17
CZ298556B6 (cs) 2007-11-07
CN1243766C (zh) 2006-03-01
US6936592B2 (en) 2005-08-30
LU91076I2 (fr) 2004-07-05
NO996106L (no) 2000-02-10
HRP980314B1 (en) 2004-04-30
DE122004000018I2 (de) 2011-01-13
CA2293823A1 (en) 1998-12-17
US20040180842A1 (en) 2004-09-16
HN1998000086A (es) 1999-03-08
NL300150I2 (nl) 2004-09-01
ES2205487T3 (es) 2004-05-01
LU91076I9 (en) 2018-07-02
RS49675B (sr) 2007-11-15
ATE251173T1 (de) 2003-10-15
EP0988310A1 (en) 2000-03-29
AP9801255A0 (en) 1998-06-30
DZ2514A1 (fr) 2003-02-01
NL300150I1 (nl) 2004-08-02
YU58699A (enExample) 2002-08-12
DE69818665T2 (de) 2004-04-29
SK168399A3 (en) 2000-11-07
AU7347598A (en) 1998-12-30
US6420536B1 (en) 2002-07-16
EA199901015A1 (ru) 2000-06-26
NO996106D0 (no) 1999-12-10
WO1998056802A1 (en) 1998-12-17
TW472060B (en) 2002-01-11
SI0988310T1 (en) 2004-02-29
DE69818665D1 (de) 2003-11-06
IS1998B (is) 2005-03-15
JP3315704B2 (ja) 2002-08-19
DE122004000018I1 (de) 2004-09-30
IL132809A0 (en) 2001-03-19
PL337505A1 (en) 2000-08-28
ME00876B (me) 2012-06-20
HRP980314A2 (en) 1999-04-30
HUP0002209A3 (en) 2003-05-28
MA24564A1 (fr) 1998-12-31
AP1231A (en) 2003-12-11
PL191601B1 (pl) 2006-06-30
US20040023896A1 (en) 2004-02-05
EP0988310B1 (en) 2003-10-01
BG103945A (en) 2000-07-31
TNSN98082A1 (fr) 2005-03-15
KR100396168B1 (ko) 2003-08-27
DK0988310T3 (da) 2003-12-15
KR20010013632A (ko) 2001-02-26
BRPI9810519B8 (pt) 2022-11-16
SK284171B6 (sk) 2004-10-05
OA11224A (en) 2003-07-16
HK1068893A1 (en) 2005-07-29
NO316911B1 (no) 2004-06-21
NZ514871A (en) 2003-08-29
PA8452201A1 (es) 2000-05-24
US6777393B2 (en) 2004-08-17
UA67744C2 (uk) 2004-07-15
AU749816B2 (en) 2002-07-04
US20020061858A1 (en) 2002-05-23
CN1172947C (zh) 2004-10-27
BG64391B1 (bg) 2004-12-30
EP0988310B9 (en) 2006-03-08
CN101691390A (zh) 2010-04-07
CN1259136A (zh) 2000-07-05

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