NL300150I1 - 4"-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten. - Google Patents

4"-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten.

Info

Publication number
NL300150I1
NL300150I1 NL300150C NL300150C NL300150I1 NL 300150 I1 NL300150 I1 NL 300150I1 NL 300150 C NL300150 C NL 300150C NL 300150 C NL300150 C NL 300150C NL 300150 I1 NL300150 I1 NL 300150I1
Authority
NL
Netherlands
Prior art keywords
homoerythromycin
deoxo
aza
derivatives
substituted
Prior art date
Application number
NL300150C
Other languages
English (en)
Other versions
NL300150I2 (nl
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300150(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NL300150I1 publication Critical patent/NL300150I1/nl
Publication of NL300150I2 publication Critical patent/NL300150I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NL300150C 1997-06-11 2004-05-10 4 "-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten. NL300150I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11
PCT/IB1998/000839 WO1998056802A1 (en) 1997-06-11 1998-05-29 4'-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Publications (2)

Publication Number Publication Date
NL300150I1 true NL300150I1 (nl) 2004-08-02
NL300150I2 NL300150I2 (nl) 2004-09-01

Family

ID=21959336

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300150C NL300150I2 (nl) 1997-06-11 2004-05-10 4 "-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten.

Country Status (50)

Country Link
US (4) US6420536B1 (nl)
EP (1) EP0988310B9 (nl)
JP (2) JP3315704B2 (nl)
KR (1) KR100396168B1 (nl)
CN (4) CN1172947C (nl)
AP (1) AP1231A (nl)
AR (1) AR013086A1 (nl)
AT (1) ATE251173T1 (nl)
AU (1) AU749816B2 (nl)
BG (1) BG64391B1 (nl)
BR (1) BRPI9810519B8 (nl)
CA (1) CA2293823C (nl)
CO (1) CO4950611A1 (nl)
CZ (1) CZ298556B6 (nl)
DE (2) DE122004000018I2 (nl)
DK (1) DK0988310T3 (nl)
DZ (1) DZ2514A1 (nl)
EA (1) EA002441B1 (nl)
EG (1) EG24081A (nl)
ES (1) ES2205487T3 (nl)
FR (1) FR04C0013I2 (nl)
GT (1) GT199800077A (nl)
HK (3) HK1028048A1 (nl)
HN (1) HN1998000086A (nl)
HR (1) HRP980314B1 (nl)
HU (2) HU228005B1 (nl)
ID (1) ID22992A (nl)
IL (1) IL132809A0 (nl)
IS (1) IS1998B (nl)
LU (1) LU91076I9 (nl)
MA (1) MA24564A1 (nl)
ME (1) ME00876B (nl)
MY (1) MY123354A (nl)
NL (1) NL300150I2 (nl)
NO (1) NO316911B1 (nl)
NZ (2) NZ514871A (nl)
OA (1) OA11224A (nl)
PA (1) PA8452201A1 (nl)
PE (1) PE79699A1 (nl)
PL (1) PL191601B1 (nl)
PT (1) PT988310E (nl)
RS (1) RS49675B (nl)
SI (1) SI0988310T1 (nl)
SK (1) SK284171B6 (nl)
TN (1) TNSN98082A1 (nl)
TW (1) TW472060B (nl)
UA (1) UA67744C2 (nl)
UY (1) UY25040A1 (nl)
WO (1) WO1998056802A1 (nl)
ZA (1) ZA985017B (nl)

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EP1779853A3 (en) * 1997-09-10 2010-01-27 Merial Ltd. 9a-azalides as veterinary antimicrobial agents
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EP1437360A3 (en) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11 Carbamates of macrolide antibacterials
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
CA2292359C (en) * 1999-01-28 2004-09-28 Pfizer Products Inc. Novel azalides and methods of making same
PL353316A1 (en) * 1999-05-18 2003-11-17 Pfizer Products Inc. Novel crystalline forms of a macrolide antibiotic
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
EP1206476B1 (en) * 1999-08-24 2006-01-04 Abbott Laboratories 9a-azalides with antibacterial activity
US6608033B1 (en) * 1999-08-27 2003-08-19 Pfizer Inc. Treatment or prevention of coccidiosis
NZ518665A (en) * 2000-01-27 2005-02-25 Pfizer Prod Inc Azalide antibiotic compositions
WO2001081358A1 (en) * 2000-04-27 2001-11-01 Pfizer Products Inc. The use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals
BR0209241A (pt) * 2001-04-27 2004-06-15 Pfizer Prod Inc Processo para preparação de derivados de9-deoxo-9a-aza-9a-homoeritromicina a 4-substituida
WO2003011266A2 (en) * 2001-08-01 2003-02-13 Pfizer Products Inc. Azalide antibiotic compositions
EP3738591A3 (en) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
CN1882360A (zh) * 2003-11-21 2006-12-20 辉瑞产品公司 抗生素作为疫苗佐剂的用途
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US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
US7767797B1 (en) * 2004-09-30 2010-08-03 Synovo Gmbh Macrocyclic compounds and methods of use thereof
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
DE602006006546D1 (de) * 2005-01-14 2009-06-10 Glaxosmithkline Zagreb 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
SI2358379T1 (sl) 2008-10-24 2016-05-31 Cempra Pharmaceuticals, Inc. Postopki biološke obrambe z makrolidi, ki vsebujejo triazol
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
KR20180101643A (ko) 2010-03-22 2018-09-12 셈프라 파마슈티컬스, 인크. 매크로라이드의 결정 형태들 및 그 용도들
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
EP2619214B1 (en) 2010-09-20 2014-12-24 Novartis AG Novel process for the preparation of 9-deoxo-9a-aza-9a-homoerythromycin a modified in the c-4'' of the cladinose ring by an epoxide group
US9145436B2 (en) * 2010-10-10 2015-09-29 Michael W. Burnet Anti-inflammatory macrolides
CN102993250B (zh) * 2011-07-06 2016-02-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
EP2736915A1 (en) 2011-07-27 2014-06-04 Farma GRS, d.o.o. New crystalline forms of tulathromycin
KR20140139083A (ko) 2012-03-27 2014-12-04 셈프라 파마슈티컬스, 인크. 마크롤라이드계 항생제를 투여하기 위한 비경구 제제
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
WO2015014907A1 (en) * 2013-07-31 2015-02-05 Farma Grs, D.O.O. Process for preparation of tulathromycin
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普（天津）生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
FR3048612B1 (fr) * 2016-03-14 2020-10-02 Septeos Tulathromycine potentialisee
CN106046077B (zh) * 2016-08-04 2019-07-26 湖北美天生物科技股份有限公司 一种泰拉霉素a的合成方法
CN108003207B (zh) 2017-12-19 2019-05-10 海门慧聚药业有限公司 制备泰拉霉素的方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法

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Also Published As

Publication number Publication date
AR013086A1 (es) 2000-12-13
DE69818665T2 (de) 2004-04-29
CN1566129A (zh) 2005-01-19
EP0988310B9 (en) 2006-03-08
ME00876B (me) 2012-06-20
NO316911B1 (no) 2004-06-21
SK284171B6 (sk) 2004-10-05
PA8452201A1 (es) 2000-05-24
FR04C0013I2 (nl) 2005-10-21
HN1998000086A (es) 1999-03-08
NZ500660A (en) 2002-03-01
DZ2514A1 (fr) 2003-02-01
DE122004000018I1 (de) 2004-09-30
US6777393B2 (en) 2004-08-17
BRPI9810519A (pt) 2000-09-19
SI0988310T1 (en) 2004-02-29
PL191601B1 (pl) 2006-06-30
AU7347598A (en) 1998-12-30
IS5252A (is) 1999-11-16
JP3315704B2 (ja) 2002-08-19
CA2293823A1 (en) 1998-12-17
JP2002316933A (ja) 2002-10-31
PT988310E (pt) 2003-12-31
CN1243766C (zh) 2006-03-01
LU91076I2 (fr) 2004-07-05
KR100396168B1 (ko) 2003-08-27
ATE251173T1 (de) 2003-10-15
AP1231A (en) 2003-12-11
HRP980314A2 (en) 1999-04-30
CZ442199A3 (cs) 2000-07-12
TW472060B (en) 2002-01-11
CN101691390A (zh) 2010-04-07
DK0988310T3 (da) 2003-12-15
DE69818665D1 (de) 2003-11-06
AP9801255A0 (en) 1998-06-30
KR20010013632A (ko) 2001-02-26
IL132809A0 (en) 2001-03-19
HUP0002209A3 (en) 2003-05-28
MA24564A1 (fr) 1998-12-31
US20040023896A1 (en) 2004-02-05
NO996106D0 (no) 1999-12-10
JP2000514098A (ja) 2000-10-24
BRPI9810519B1 (pt) 2012-02-22
MY123354A (en) 2006-05-31
HK1028048A1 (en) 2001-02-02
BG103945A (en) 2000-07-31
CA2293823C (en) 2004-02-17
IS1998B (is) 2005-03-15
PE79699A1 (es) 1999-08-25
HUS1200028I1 (hu) 2016-08-29
EA002441B1 (ru) 2002-04-25
HK1088014A1 (en) 2006-10-27
DE122004000018I2 (de) 2011-01-13
US20040180842A1 (en) 2004-09-16
HRP980314B1 (en) 2004-04-30
ES2205487T3 (es) 2004-05-01
TNSN98082A1 (fr) 2005-03-15
GT199800077A (es) 1999-12-02
OA11224A (en) 2003-07-16
BRPI9810519B8 (pt) 2022-11-16
HU228005B1 (en) 2012-08-28
NZ514871A (en) 2003-08-29
EP0988310A1 (en) 2000-03-29
HUP0002209A2 (hu) 2000-12-28
CN1259136A (zh) 2000-07-05
CZ298556B6 (cs) 2007-11-07
FR04C0013I1 (nl) 2004-06-11
CN1793155B (zh) 2010-05-12
SK168399A3 (en) 2000-11-07
US6936592B2 (en) 2005-08-30
AU749816B2 (en) 2002-07-04
UY25040A1 (es) 2000-09-29
CO4950611A1 (es) 2000-09-01
ZA985017B (en) 1999-12-17
RS49675B (sr) 2007-11-15
YU58699A (nl) 2002-08-12
BG64391B1 (bg) 2004-12-30
NL300150I2 (nl) 2004-09-01
WO1998056802A1 (en) 1998-12-17
LU91076I9 (en) 2018-07-02
NO996106L (no) 2000-02-10
HK1068893A1 (en) 2005-07-29
UA67744C2 (uk) 2004-07-15
US6420536B1 (en) 2002-07-16
US20020061858A1 (en) 2002-05-23
PL337505A1 (en) 2000-08-28
ID22992A (id) 1999-12-23
EG24081A (en) 2008-05-11
CN1172947C (zh) 2004-10-27
EP0988310B1 (en) 2003-10-01
CN1793155A (zh) 2006-06-28
EA199901015A1 (ru) 2000-06-26

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