MX344293B - Combinacion de una insulina y un agonista de glp-1. - Google Patents

Combinacion de una insulina y un agonista de glp-1.

Info

Publication number
MX344293B
MX344293B MX2011003804A MX2011003804A MX344293B MX 344293 B MX344293 B MX 344293B MX 2011003804 A MX2011003804 A MX 2011003804A MX 2011003804 A MX2011003804 A MX 2011003804A MX 344293 B MX344293 B MX 344293B
Authority
MX
Mexico
Prior art keywords
glp
insulin
agonist
combination
drug
Prior art date
Application number
MX2011003804A
Other languages
English (en)
Other versions
MX2011003804A (es
Inventor
Werner Ulrich
James Smith Christopher
Rotthäuser Bärbel
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42077330&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX344293(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102008051834A external-priority patent/DE102008051834A1/de
Priority claimed from DE102008053048A external-priority patent/DE102008053048A1/de
Priority claimed from DE102009038210A external-priority patent/DE102009038210A1/de
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MX2011003804A publication Critical patent/MX2011003804A/es
Publication of MX344293B publication Critical patent/MX344293B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un medicamento para tratar un paciente con diabetes tipo 1 o 2, para ajustar la concentración de glucosa sanguínea en ayunas, posprandial y/o posabsortiva, para mejorar la tolerancia a la glucosa, para prevenir la hipoglucemia, para la pérdida de peso y/o para prevenir el aumento de peso, dicho medicamento que comprende una primer composición farmacéutica y una segunda composición farmacéutica, la primera composición farmacéutica comprende Gly(A21)-Arg(B31)-Arg(B32) insulina humana y la segunda composición farmacéutica comprende Gly(A21)-Arg(B31)-Arg(B32) insulina humana y desPro36exendina-4(1-39)-Lys6-NH2 o una de sus sales farmacológicamente tolerables.
MX2011003804A 2008-10-17 2009-10-09 Combinacion de una insulina y un agonista de glp-1. MX344293B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102008051834A DE102008051834A1 (de) 2008-10-17 2008-10-17 Kombination von einem Insulin und einem GLP-1-Agonisten
DE102008053048A DE102008053048A1 (de) 2008-10-24 2008-10-24 Kombination von einem Insulin und einem GLP-1-Agonisten
DE102009038210A DE102009038210A1 (de) 2009-08-20 2009-08-20 Kombination von einem Insulin und einem GLP-1-Agonisten
PCT/EP2009/063195 WO2010043566A2 (de) 2008-10-17 2009-10-09 Kombination von einem insulin und einem glp-1-agonisten

Publications (2)

Publication Number Publication Date
MX2011003804A MX2011003804A (es) 2011-05-02
MX344293B true MX344293B (es) 2016-12-13

Family

ID=42077330

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016008764A MX349717B (es) 2008-10-17 2009-10-09 Combinación de una insulina y un agonista de glp-1.
MX2011003804A MX344293B (es) 2008-10-17 2009-10-09 Combinacion de una insulina y un agonista de glp-1.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016008764A MX349717B (es) 2008-10-17 2009-10-09 Combinación de una insulina y un agonista de glp-1.

Country Status (39)

Country Link
US (6) US9526764B2 (es)
EP (3) EP3228320B1 (es)
JP (2) JP5731981B2 (es)
KR (3) KR101939557B1 (es)
CN (3) CN105396126A (es)
AR (1) AR073872A1 (es)
AU (1) AU2009305472B2 (es)
BR (2) BRPI0920881B1 (es)
CA (2) CA2740685C (es)
CL (1) CL2011000851A1 (es)
CO (1) CO6361944A2 (es)
CR (2) CR20170369A (es)
CY (1) CY1119952T1 (es)
DK (2) DK2349324T3 (es)
DO (1) DOP2011000104A (es)
EC (1) ECSP11010986A (es)
ES (3) ES2992698T3 (es)
HK (1) HK1222568A1 (es)
HN (1) HN2011001021A (es)
HR (2) HRP20171894T1 (es)
HU (3) HUE068164T2 (es)
IL (2) IL212258A (es)
LT (2) LT2349324T (es)
MA (1) MA32703B1 (es)
MX (2) MX349717B (es)
NI (1) NI201100068A (es)
NZ (1) NZ592283A (es)
PA (1) PA8845901A1 (es)
PE (1) PE20120060A1 (es)
PL (3) PL2349324T3 (es)
PT (3) PT3228320T (es)
RS (2) RS59913B1 (es)
RU (1) RU2532378C2 (es)
SI (2) SI3228320T1 (es)
TN (1) TN2011000160A1 (es)
TW (1) TWI494121B (es)
UY (1) UY32183A (es)
WO (1) WO2010043566A2 (es)
ZA (1) ZA201102400B (es)

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