DK347086D0 - Novel peptides - Google Patents

Novel peptides

Info

Publication number
DK347086D0
DK347086D0 DK347086A DK347086A DK347086D0 DK 347086 D0 DK347086 D0 DK 347086D0 DK 347086 A DK347086 A DK 347086A DK 347086 A DK347086 A DK 347086A DK 347086 D0 DK347086 D0 DK 347086D0
Authority
DK
Denmark
Prior art keywords
amino acid
solutions
insulin
asn
substituted
Prior art date
Application number
DK347086A
Other languages
English (en)
Inventor
Jan Markussen
Kjeld Norris
Liselotte Langkjaer
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8123250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK347086(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK347086A priority Critical patent/DK347086D0/da
Publication of DK347086D0 publication Critical patent/DK347086D0/da
Priority to IL83243A priority patent/IL83243A/xx
Priority to PT85355A priority patent/PT85355B/pt
Priority to DD87305161A priority patent/DD273839A5/de
Priority to DE2000175024 priority patent/DE10075024I1/de
Priority to US07/075,387 priority patent/US4946828A/en
Priority to ZA875295A priority patent/ZA875295B/xx
Priority to DE3788684T priority patent/DE3788684T2/de
Priority to FI873185A priority patent/FI873185A/fi
Priority to DK376187A priority patent/DK160880C/da
Priority to AT87306405T priority patent/ATE99699T1/de
Priority to CN198787104988A priority patent/CN87104988A/zh
Priority to ES87306405T priority patent/ES2061504T3/es
Priority to MYPI87001062A priority patent/MY102873A/en
Priority to YU01353/87A priority patent/YU135387A/xx
Priority to HU873343A priority patent/HU203371B/hu
Priority to KR1019870007832A priority patent/KR880001701A/ko
Priority to AU75916/87A priority patent/AU612324B2/en
Priority to NO873018A priority patent/NO170978C/no
Priority to NZ221130A priority patent/NZ221130A/xx
Priority to EP87306405A priority patent/EP0254516B1/en
Priority to JP62180168A priority patent/JPS6399096A/ja
Priority to US07/424,503 priority patent/US5008241A/en
Priority to NL300018C priority patent/NL300018I1/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK347086A 1985-03-12 1986-07-21 Novel peptides DK347086D0 (da)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides
NZ221130A NZ221130A (en) 1986-07-21 1987-07-20 Insulin analogues with greater positive charge than human insulin at neutral ph
EP87306405A EP0254516B1 (en) 1986-07-21 1987-07-20 Novel Peptides
DK376187A DK160880C (da) 1986-07-21 1987-07-20 Insulinderivater samt injicerbare oploesninger indeholdende disse
ES87306405T ES2061504T3 (es) 1986-07-21 1987-07-20 Nuevos peptidos.
DD87305161A DD273839A5 (de) 1986-07-21 1987-07-20 Verfahren zur herstellung neuer insulinderivate
DE2000175024 DE10075024I1 (de) 1986-07-21 1987-07-20 Peptide
US07/075,387 US4946828A (en) 1985-03-12 1987-07-20 Novel insulin peptides
ZA875295A ZA875295B (en) 1986-07-21 1987-07-20 Novel peptides
DE3788684T DE3788684T2 (de) 1986-07-21 1987-07-20 Peptide.
FI873185A FI873185A (fi) 1986-07-21 1987-07-20 Nya peptider.
IL83243A IL83243A (en) 1986-07-21 1987-07-20 Insulin derivatives optionally having alterations in the a4, a17, a21, b13, b21 and b27 positions
AT87306405T ATE99699T1 (de) 1986-07-21 1987-07-20 Peptide.
CN198787104988A CN87104988A (zh) 1986-07-21 1987-07-20 新的多肽
PT85355A PT85355B (pt) 1986-07-21 1987-07-20 Processo para a preparacao de novos peptidos
MYPI87001062A MY102873A (en) 1986-07-21 1987-07-20 Novel peptides
YU01353/87A YU135387A (en) 1986-07-21 1987-07-20 Process for obtaining new peptides
HU873343A HU203371B (en) 1986-07-21 1987-07-20 Process for producing new insulin derivatives and injection solutions comprising same
KR1019870007832A KR880001701A (ko) 1986-07-21 1987-07-20 신규한 펩티드
AU75916/87A AU612324B2 (en) 1986-07-21 1987-07-20 Novel peptides and injectable solutions having prolonged insulin action
NO873018A NO170978C (no) 1986-07-21 1987-07-20 Analogifremgangsmaate ved fremstilling av nye peptider
JP62180168A JPS6399096A (ja) 1986-07-21 1987-07-21 インシュリン誘導体
US07/424,503 US5008241A (en) 1985-03-12 1989-10-20 Novel insulin peptides
NL300018C NL300018I1 (nl) 1986-07-21 2000-09-15 Nieuwe peptiden.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides

Publications (1)

Publication Number Publication Date
DK347086D0 true DK347086D0 (da) 1986-07-21

Family

ID=8123250

Family Applications (1)

Application Number Title Priority Date Filing Date
DK347086A DK347086D0 (da) 1985-03-12 1986-07-21 Novel peptides

Country Status (20)

Country Link
EP (1) EP0254516B1 (da)
JP (1) JPS6399096A (da)
KR (1) KR880001701A (da)
CN (1) CN87104988A (da)
AT (1) ATE99699T1 (da)
AU (1) AU612324B2 (da)
DD (1) DD273839A5 (da)
DE (2) DE10075024I1 (da)
DK (1) DK347086D0 (da)
ES (1) ES2061504T3 (da)
FI (1) FI873185A (da)
HU (1) HU203371B (da)
IL (1) IL83243A (da)
MY (1) MY102873A (da)
NL (1) NL300018I1 (da)
NO (1) NO170978C (da)
NZ (1) NZ221130A (da)
PT (1) PT85355B (da)
YU (1) YU135387A (da)
ZA (1) ZA875295B (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006599A1 (en) * 1987-02-25 1988-09-07 Novo Industri A/S Novel insulin derivatives
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
WO1990001038A1 (en) * 1988-07-20 1990-02-08 Nordisk Gentofte A/S Human insulin analogs and preparations containing them
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
AU641631B2 (en) * 1988-12-23 1993-09-30 Novo Nordisk A/S Human insulin analogues
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US7316999B2 (en) 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
WO2003044210A2 (en) 2001-11-19 2003-05-30 Novo Nordisk A/S Process for preparing insulin compounds
GB0206792D0 (en) 2002-03-22 2002-05-01 Leuven K U Res & Dev Normoglycemia
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
DE602004032237D1 (de) 2003-06-27 2011-05-26 Novo Nordisk As Behälter für medizinische flüssigkeiten mit hoher wasserdampfsperre
EP1699629B1 (en) 2003-12-22 2010-10-06 Novo Nordisk A/S Transparent, flexible , impermeable plastic container for storage of pharmaceutical liquids
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
WO2008049711A1 (en) 2006-10-27 2008-05-02 Novo Nordisk A/S Peptide extended insulins
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
MY152979A (en) * 2008-01-09 2014-12-15 Sanofi Aventis Deutschland Novel insulin derivatives having an extremely delayed time-action profile
RU2571857C2 (ru) 2008-03-18 2015-12-20 Ново Нордиск А/С Стабилизированные по отношению к протеазам ацилированные аналоги инсулина
TWI451876B (zh) 2008-06-13 2014-09-11 Lilly Co Eli 聚乙二醇化之離脯胰島素化合物
JP5903269B2 (ja) 2008-08-07 2016-04-13 バイオコン リミテッド インスリン化合物の調製方法
KR101939557B1 (ko) 2008-10-17 2019-01-17 사노피-아벤티스 도이칠란트 게엠베하 인슐린과 ｇｌｐ－1 효능제의 병용물
JP2012532177A (ja) * 2009-07-06 2012-12-13 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 熱及び振動安定性インスリン製剤
AU2010317994B2 (en) 2009-11-13 2014-03-06 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
RU2537239C2 (ru) 2009-11-13 2014-12-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
EP2359843A1 (en) 2010-01-21 2011-08-24 Sanofi Pharmaceutical composition for treating a metabolic syndrome
AR080884A1 (es) 2010-04-14 2012-05-16 Sanofi Aventis Conjugados de insulina-sirna
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
EP2548570A1 (en) 2011-07-19 2013-01-23 Sanofi Pharmaceutical composition for treating a metabolic syndrome
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病患者の血糖コントロールに使用する組合せ医薬
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
MX2014012096A (es) 2012-04-11 2014-11-21 Novo Nordisk As Formulaciones de insulina.
WO2015196174A1 (en) 2014-06-20 2015-12-23 Greene Howard E Infusion delivery devices and methods
NZ733670A (en) 2014-12-12 2021-12-24 Sanofi Aventis Deutschland Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
HRP20221324T1 (hr) 2016-12-16 2022-12-23 Novo Nordisk A/S Farmaceutski pripravci koji sadrže inzulin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033127A1 (de) * 1980-09-03 1982-04-08 Hoechst Ag, 6000 Frankfurt Neue analoga des insulins
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
EP0254516B1 (en) 1994-01-05
NZ221130A (en) 1990-08-28
ATE99699T1 (de) 1994-01-15
EP0254516A3 (en) 1990-06-27
IL83243A (en) 1993-01-14
PT85355B (pt) 1990-04-30
HUT45271A (en) 1988-06-28
DD273839A5 (de) 1989-11-29
ZA875295B (en) 1988-01-21
JPS6399096A (ja) 1988-04-30
DE3788684D1 (de) 1994-02-17
NO873018L (no) 1988-01-22
AU7591687A (en) 1988-01-28
CN87104988A (zh) 1988-03-02
AU612324B2 (en) 1991-07-11
KR880001701A (ko) 1988-04-26
EP0254516A2 (en) 1988-01-27
DE3788684T2 (de) 1994-05-19
PT85355A (en) 1987-08-01
MY102873A (en) 1993-03-31
HU203371B (en) 1991-07-29
ES2061504T3 (es) 1994-12-16
YU135387A (en) 1988-10-31
NO873018D0 (no) 1987-07-20
FI873185A0 (fi) 1987-07-20
NO170978C (no) 1993-01-06
NL300018I1 (nl) 2000-11-01
IL83243A0 (en) 1987-12-31
NO170978B (no) 1992-09-28
DE10075024I1 (de) 2000-11-09
FI873185A (fi) 1988-01-22

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Legal Events

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