MX2018014501A - Modificacion del genoma usando sistemas guia de polinucleotido/cas endonucleasa y metodos de uso. - Google Patents

Modificacion del genoma usando sistemas guia de polinucleotido/cas endonucleasa y metodos de uso.

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Publication number
MX2018014501A
MX2018014501A MX2018014501A MX2018014501A MX2018014501A MX 2018014501 A MX2018014501 A MX 2018014501A MX 2018014501 A MX2018014501 A MX 2018014501A MX 2018014501 A MX2018014501 A MX 2018014501A MX 2018014501 A MX2018014501 A MX 2018014501A
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MX
Mexico
Prior art keywords
methods
genome
cas endonuclease
cell
guide polynucleotide
Prior art date
Application number
MX2018014501A
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English (en)
Inventor
Joshua K Young
Phillip A Patten
Andrew Cigan
Original Assignee
Pioneer Hi Bred Int
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Application filed by Pioneer Hi Bred Int filed Critical Pioneer Hi Bred Int
Publication of MX2018014501A publication Critical patent/MX2018014501A/es

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Abstract

Se proporcionan composiciones y métodos para la modificación genómica de una secuencia objetivo en el genoma de una célula. Los métodos y composiciones usan un sistema de polinucleótido guía/endonucleasa Cas para proporcionar un sistema eficaz para modificar o alterar sitios objetivo dentro del genoma de una célula u organismo. Una vez que se identificó un sitio genómico objetivo puede usarse diversos métodos para modificar, además, los sitios objetivo de manera que contengan diversos polinucleótidos de interés. Además, se proporciona composiciones y métodos para editar una secuencia de nucleótidos en el genoma de una célula. Además, se describen métodos de cultivo y métodos para seleccionar plantas con el uso de un sistema bicomponente de polinucleótido de ARN y endonucleasa CAS.
MX2018014501A 2013-08-22 2016-02-19 Modificacion del genoma usando sistemas guia de polinucleotido/cas endonucleasa y metodos de uso. MX2018014501A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361868706P 2013-08-22 2013-08-22
US201361882532P 2013-09-25 2013-09-25
US201461937045P 2014-02-07 2014-02-07
US201461953090P 2014-03-14 2014-03-14
US201462023239P 2014-07-11 2014-07-11

Publications (1)

Publication Number Publication Date
MX2018014501A true MX2018014501A (es) 2020-09-14

Family

ID=51493053

Family Applications (5)

Application Number Title Priority Date Filing Date
MX2016002306A MX2016002306A (es) 2013-08-22 2014-08-20 Promotor u6 de polimerasa iii de soja y metodos de uso.
MX2016002118A MX2016002118A (es) 2013-08-22 2014-08-20 Modificacion del genoma de plantas por medio del uso de sistemas de ácido ribonucléico (arn) guía/ endonucleasa cas y metodos de uso.
MX2016002266A MX361154B (es) 2013-08-22 2014-08-20 Modificación del genoma usando sistemas guía de polinucleótido/cas endonucleasa y métodos de uso.
MX2016002119A MX363842B (es) 2013-08-22 2014-08-20 Métodos para producir modificaciones genéticas en un genoma vegetal sin incorporar un marcador transgénico seleccionable, y composiciones de éstas.
MX2018014501A MX2018014501A (es) 2013-08-22 2016-02-19 Modificacion del genoma usando sistemas guia de polinucleotido/cas endonucleasa y metodos de uso.

Family Applications Before (4)

Application Number Title Priority Date Filing Date
MX2016002306A MX2016002306A (es) 2013-08-22 2014-08-20 Promotor u6 de polimerasa iii de soja y metodos de uso.
MX2016002118A MX2016002118A (es) 2013-08-22 2014-08-20 Modificacion del genoma de plantas por medio del uso de sistemas de ácido ribonucléico (arn) guía/ endonucleasa cas y metodos de uso.
MX2016002266A MX361154B (es) 2013-08-22 2014-08-20 Modificación del genoma usando sistemas guía de polinucleótido/cas endonucleasa y métodos de uso.
MX2016002119A MX363842B (es) 2013-08-22 2014-08-20 Métodos para producir modificaciones genéticas en un genoma vegetal sin incorporar un marcador transgénico seleccionable, y composiciones de éstas.

Country Status (12)

Country Link
US (16) US20150082478A1 (es)
EP (6) EP3036333B1 (es)
CN (4) CN105916989A (es)
AU (6) AU2014308899B2 (es)
BR (4) BR112016003578A2 (es)
CA (7) CA2922040C (es)
DK (1) DK3036327T3 (es)
ES (1) ES2729635T3 (es)
HU (1) HUE044916T2 (es)
LT (1) LT3036327T (es)
MX (5) MX2016002306A (es)
WO (4) WO2015026883A1 (es)

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MX2013010911A (es) 2011-03-23 2015-03-03 Pioneer Hi Bred Int Metodos para producir un locus de rasgo transgenico complejo.
US10323236B2 (en) 2011-07-22 2019-06-18 President And Fellows Of Harvard College Evaluation and improvement of nuclease cleavage specificity
EP2861737B1 (en) 2012-06-19 2019-04-17 Regents Of The University Of Minnesota Gene targeting in plants using dna viruses
ES2926021T3 (es) * 2012-10-23 2022-10-21 Toolgen Inc Composición para escindir un ADN objetivo que comprende un ARN guía específico para el ADN objetivo y ácido nucleico codificador de proteína Cas o proteína Cas, y uso de la misma
DK2986729T3 (en) 2013-04-16 2018-10-29 Regeneron Pharma TARGETED MODIFICATION OF ROOT THROUGH
WO2014199358A1 (en) 2013-06-14 2014-12-18 Cellectis Methods for non-transgenic genome editing in plants
US20150044192A1 (en) 2013-08-09 2015-02-12 President And Fellows Of Harvard College Methods for identifying a target site of a cas9 nuclease
AU2014308899B2 (en) 2013-08-22 2020-11-19 E. I. Du Pont De Nemours And Company Methods for producing genetic modifications in a plant genome without incorporating a selectable transgene marker, and compositions thereof
US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
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