BR112016001721A2 - Engenharia genômica - Google Patents

Engenharia genômica

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Publication number
BR112016001721A2
BR112016001721A2 BR112016001721A BR112016001721A BR112016001721A2 BR 112016001721 A2 BR112016001721 A2 BR 112016001721A2 BR 112016001721 A BR112016001721 A BR 112016001721A BR 112016001721 A BR112016001721 A BR 112016001721A BR 112016001721 A2 BR112016001721 A2 BR 112016001721A2
Authority
BR
Brazil
Prior art keywords
genomic engineering
genomic
engineering
talen
cas9
Prior art date
Application number
BR112016001721A
Other languages
English (en)
Other versions
BR112016001721B1 (pt
Inventor
Yang Luhan
Lichi Yang Joyce
M Church George
Guell Cargol Marc
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of BR112016001721A2 publication Critical patent/BR112016001721A2/pt
Publication of BR112016001721B1 publication Critical patent/BR112016001721B1/pt

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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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    • C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible

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  • Saccharide Compounds (AREA)
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Abstract

ENGENHARIA GENÔMICA. Métodos de engenharia genômica em células utilizando um TALEN destituido de sequências de repetição ou Cas9 é provido.
BR112016001721-8A 2013-07-26 2014-07-25 Método in vitro de alteração do dna-alvo em célula-tronco tendo ácido nucleico que codifica enzima cas9 BR112016001721B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361858866P 2013-07-26 2013-07-26
US61/858.866 2013-07-26
PCT/US2014/048140 WO2015013583A2 (en) 2013-07-26 2014-07-25 Genome engineering

Publications (2)

Publication Number Publication Date
BR112016001721A2 true BR112016001721A2 (pt) 2017-09-05
BR112016001721B1 BR112016001721B1 (pt) 2023-10-03

Family

ID=52390824

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016001721-8A BR112016001721B1 (pt) 2013-07-26 2014-07-25 Método in vitro de alteração do dna-alvo em célula-tronco tendo ácido nucleico que codifica enzima cas9

Country Status (14)

Country Link
US (4) US10563225B2 (pt)
EP (4) EP3916099B1 (pt)
JP (4) JP6739335B2 (pt)
KR (2) KR20160035017A (pt)
CN (3) CN118028379A (pt)
AU (4) AU2014293015B2 (pt)
BR (1) BR112016001721B1 (pt)
CA (1) CA2918540A1 (pt)
ES (1) ES2715666T3 (pt)
HK (1) HK1218940A1 (pt)
IL (2) IL243560B (pt)
RU (2) RU2688462C2 (pt)
SG (3) SG11201600217QA (pt)
WO (1) WO2015013583A2 (pt)

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