US4281061A
(en)
|
1979-07-27 |
1981-07-28 |
Syva Company |
Double antibody for enhanced sensitivity in immunoassay
|
US4709015A
(en)
|
1979-12-04 |
1987-11-24 |
Ortho Pharmaceutical Corporation |
Monoclonal antibody to human suppressor T cells
|
US5292668A
(en)
|
1981-12-21 |
1994-03-08 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
JP2501190B2
(ja)
|
1985-12-18 |
1996-05-29 |
株式会社日立製作所 |
内燃機関用の吸入空気流量制御装置
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
FR2604092B1
(fr)
|
1986-09-19 |
1990-04-13 |
Immunotech Sa |
Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
|
US5436170A
(en)
|
1987-07-27 |
1995-07-25 |
Commonwealth Scientific And Industrial Research Organization |
Receptor membranes
|
GB8720833D0
(en)
|
1987-09-04 |
1987-10-14 |
Celltech Ltd |
Recombinant dna product
|
US4943525A
(en)
|
1987-11-02 |
1990-07-24 |
Bioventures, Inc. |
Simultaneous immunoassay for the determination of antigens and antibodies
|
US5869053A
(en)
|
1988-03-04 |
1999-02-09 |
Cancer Research Campaign Technology, Ltd. |
5T4 antigen from human trophoblasts
|
US4892824A
(en)
|
1988-03-15 |
1990-01-09 |
Synbiotics Corporation |
Fast track method for producing monoclonal bi-specific immunoglobulins
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
US5851527A
(en)
|
1988-04-18 |
1998-12-22 |
Immunomedics, Inc. |
Method for antibody targeting of therapeutic agents
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
WO1990005144A1
(en)
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
US5980896A
(en)
|
1989-06-30 |
1999-11-09 |
Bristol-Myers Squibb Company |
Antibodies reactive with human carcinomas
|
US5332567A
(en)
|
1989-08-24 |
1994-07-26 |
Immunomedics |
Detection and treatment of infections with immunoconjugates
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
US6197298B1
(en)
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
DE4134982A1
(de)
|
1991-10-23 |
1993-04-29 |
Kernforschungsz Karlsruhe |
Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
DE4140142A1
(de)
|
1991-12-05 |
1993-06-09 |
Boehringer Mannheim Gmbh, 6800 Mannheim, De |
Multivalentes dextranreagenz zum einsatz in praezipitationstests
|
WO1993012232A1
(en)
|
1991-12-10 |
1993-06-24 |
Dana Farber Cancer Institute |
Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof
|
DE69233204T2
(de)
|
1991-12-13 |
2004-07-15 |
Xoma Corp., Berkeley |
Verfahren und materialien zur herstellung von modifizierten variablen antikörperdomänen und ihre therapeutische verwendung
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
EP0625200B1
(en)
|
1992-02-06 |
2005-05-11 |
Chiron Corporation |
Biosynthetic binding protein for cancer marker
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
US6096289A
(en)
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
ZA936260B
(en)
|
1992-09-09 |
1994-03-18 |
Smithkline Beecham Corp |
Novel antibodies for conferring passive immunity against infection by a pathogen in man
|
US20080152586A1
(en)
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
EP0672068A4
(en)
|
1992-09-25 |
1997-02-26 |
Commw Scient Ind Res Org |
TARGET MOLECULES BINDING POLYPEPTIDES.
|
AU5322494A
(en)
|
1992-10-02 |
1994-04-26 |
Trustees Of Dartmouth College |
Bispecific reagents for redirected targeting of low density lipoprotein
|
WO1994009817A1
(en)
|
1992-11-04 |
1994-05-11 |
City Of Hope |
Novel antibody construct
|
US7105159B1
(en)
|
1992-11-05 |
2006-09-12 |
Sloan-Kettering Institute For Cancer Research |
Antibodies to prostate-specific membrane antigen
|
ATE342356T1
(de)
|
1992-11-05 |
2006-11-15 |
Sloan Kettering Inst Cancer |
Prostata-spezifisches membranantigen
|
US6953668B1
(en)
|
1992-11-05 |
2005-10-11 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
US7070782B1
(en)
|
1992-11-05 |
2006-07-04 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
AU5670194A
(en)
|
1992-11-20 |
1994-06-22 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
US5376249A
(en)
|
1992-11-25 |
1994-12-27 |
Perseptive Biosystems, Inc. |
Analysis utilizing isoelectric focusing
|
GB9225453D0
(en)
|
1992-12-04 |
1993-01-27 |
Medical Res Council |
Binding proteins
|
ATE199392T1
(de)
|
1992-12-04 |
2001-03-15 |
Medical Res Council |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
EP0628078B1
(en)
|
1992-12-11 |
1999-12-08 |
The Dow Chemical Company |
Multivalent single chain antibodies
|
US5861156A
(en)
|
1993-01-08 |
1999-01-19 |
Creative Biomolecules |
Methods of delivering agents to target cells
|
US5705614A
(en)
|
1993-04-09 |
1998-01-06 |
Chiron Corporation |
Methods of producing antigen forks
|
US6491916B1
(en)
|
1994-06-01 |
2002-12-10 |
Tolerance Therapeutics, Inc. |
Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
|
US20030108548A1
(en)
|
1993-06-01 |
2003-06-12 |
Bluestone Jeffrey A. |
Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
|
US6001581A
(en)
|
1993-06-04 |
1999-12-14 |
Sibia Neurosciences, Inc. |
Cation-based bioassay using human metabotropic glutamate receptors
|
US5521297A
(en)
|
1993-06-04 |
1996-05-28 |
Salk Institute Biotechnology/Industrial Associates |
Nucleic acids encoding human metabotropic glutamate receptors
|
US5912122A
(en)
|
1993-06-04 |
1999-06-15 |
Sibia Neurosciences, Inc. |
Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6
|
US5869049A
(en)
|
1993-09-02 |
1999-02-09 |
Trustees Of Dartmouth College |
Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists
|
ZA946765B
(en)
|
1993-09-02 |
1996-02-15 |
Dartmouth College |
Methods of prolonged suppression of humoral immunity
|
CA2171206A1
(en)
|
1993-09-20 |
1995-03-30 |
Peter Josef Flor |
Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds
|
US5935818A
(en)
|
1995-02-24 |
1999-08-10 |
Sloan-Kettering Institute For Cancer Research |
Isolated nucleic acid molecule encoding alternatively spliced prostate-specific membrane antigen and uses thereof
|
US6569432B1
(en)
|
1995-02-24 |
2003-05-27 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
GB9324807D0
(en)
|
1993-12-03 |
1994-01-19 |
Cancer Res Campaign Tech |
Tumour antibody
|
US7435802B2
(en)
|
1994-01-25 |
2008-10-14 |
Elan Pharaceuticals, Inc. |
Humanized anti-VLA4 immunoglobulins
|
WO1995022609A2
(en)
|
1994-02-21 |
1995-08-24 |
The Wellcome Foundation Limited |
Human glutamate receptor proteins
|
DE4421391C1
(de)
|
1994-06-18 |
1995-11-30 |
Gsf Forschungszentrum Umwelt |
Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
|
US5559099A
(en)
|
1994-09-08 |
1996-09-24 |
Genvec, Inc. |
Penton base protein and methods of using same
|
US5541087A
(en)
|
1994-09-14 |
1996-07-30 |
Fuji Immunopharmaceuticals Corporation |
Expression and export technology of proteins as immunofusins
|
US5688690A
(en)
|
1994-09-16 |
1997-11-18 |
The Wistar Institute Of Anatomy And Biology |
Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
|
CA2212846A1
(en)
|
1995-02-24 |
1996-08-29 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
GB9504344D0
(en)
|
1995-03-03 |
1995-04-19 |
Unilever Plc |
Antibody fragment production
|
US5747035A
(en)
|
1995-04-14 |
1998-05-05 |
Genentech, Inc. |
Polypeptides with increased half-life for use in treating disorders involving the LFA-1 receptor
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
US5773292A
(en)
|
1995-06-05 |
1998-06-30 |
Cornell University |
Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
|
US5830478A
(en)
|
1995-06-07 |
1998-11-03 |
Boston Biomedical Research Institute |
Method for delivering functional domains of diphtheria toxin to a cellular target
|
EP0873363B1
(en)
|
1995-06-14 |
2010-10-06 |
The Regents of The University of California |
High affinity human antibodies to tumor antigens
|
BR9606706A
(pt)
|
1995-10-16 |
1999-04-06 |
Unilever Nv |
Análogo de fragmento de anticorpo biespecífico ou bivalente uso processo para produzir o mesmo
|
ES2219699T3
(es)
|
1995-10-19 |
2004-12-01 |
Bristol-Myers Squibb Company |
Anticuerpo monoclonal br110 y usos del mismo.
|
US6084084A
(en)
|
1996-02-21 |
2000-07-04 |
Nps Pharmaceuticals, Inc. |
Human metabotropic glutamate receptor
|
US20040253246A1
(en)
|
1996-02-23 |
2004-12-16 |
Israeli Ron S. |
Prostate-specific membrane antigen and uses thereof
|
US6384205B1
(en)
|
1996-03-12 |
2002-05-07 |
Eli Lilly And Company |
Metabotropic glutamate receptor 4 nucleic acid
|
DE69735294T2
(de)
|
1996-03-25 |
2006-09-21 |
Medarex Inc. |
Spezifische monoklonale antikörper für die extrazelluläre domäne von protasta-spezifischem membranantigen
|
US6150508A
(en)
|
1996-03-25 |
2000-11-21 |
Northwest Biotherapeutics, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
JP2000503773A
(ja)
|
1996-05-23 |
2000-03-28 |
ユニリーバー・ナームローゼ・ベンノートシヤープ |
特異的結合アッセイの改良
|
US6221609B1
(en)
|
1996-07-03 |
2001-04-24 |
Eli Lilly And Company |
Isolate nucleic acid encoding human MGLUR8
|
WO1998000543A1
(en)
|
1996-07-03 |
1998-01-08 |
Genentech, Inc. |
Hepatocyte growth factor receptor agonists and uses thereof
|
GB9712818D0
(en)
|
1996-07-08 |
1997-08-20 |
Cambridge Antibody Tech |
Labelling and selection of specific binding molecules
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
PT932417E
(pt)
|
1996-10-17 |
2003-07-31 |
Immunomedics Inc |
Conjugado de toxina nao antigenico e proteina de fusao de sistema receptor de interiorizacao
|
JP4663824B2
(ja)
|
1996-12-31 |
2011-04-06 |
ハイ スループット ジェノミクス インコーポレイテッド |
多重化分子分析装置および方法
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
AU6914098A
(en)
|
1997-04-03 |
1998-10-30 |
Universite Laval |
Transgenic expression in genital tract and sexual accessory glands
|
ES2361267T3
(es)
|
1997-04-07 |
2011-06-15 |
Genentech Inc. |
Procedimiento para la produccion de anticuerpos humanizados mediante mutagénesis aleatoria.
|
DE19721700C1
(de)
|
1997-05-23 |
1998-11-19 |
Deutsches Krebsforsch |
Mutierter OKT3-Antikörper
|
WO1999002567A2
(en)
|
1997-07-08 |
1999-01-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods for producing homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
US6994851B1
(en)
|
1997-07-10 |
2006-02-07 |
Mannkind Corporation |
Method of inducing a CTL response
|
US6977074B2
(en)
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
CA2302360C
(en)
|
1997-09-03 |
2005-11-15 |
Immunomedics, Inc. |
Fluorination of proteins and peptides for f-18 positron emission tomography
|
GB9720054D0
(en)
|
1997-09-19 |
1997-11-19 |
Celltech Therapeutics Ltd |
Biological products
|
US6030792A
(en)
|
1997-11-13 |
2000-02-29 |
Pfizer Inc |
Assays for measurement of protein fragments in biological media
|
US6709844B1
(en)
|
2000-11-16 |
2004-03-23 |
Mannkind Corporation |
Avoidance of undesirable replication intermediates in plasmid propagation
|
DE19911329A1
(de)
|
1998-03-27 |
2000-09-21 |
Benes Ivan Friedrich |
Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
|
US7262280B1
(en)
|
1998-04-03 |
2007-08-28 |
Nps Pharmaceuticals, Inc. |
G-protein fusion receptors and constructs encoding same
|
HUP9900956A2
(hu)
|
1998-04-09 |
2002-04-29 |
Aventis Pharma Deutschland Gmbh. |
Egyláncú, több antigéntkötőhely kialakítására képes molekulák, előállításuk és alkalmazásuk
|
EP2180007B2
(en)
|
1998-04-20 |
2017-08-30 |
Roche Glycart AG |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
US6200765B1
(en)
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
US6071490A
(en)
|
1998-05-07 |
2000-06-06 |
Immunomedics, Inc. |
Position emission tomography using gallium-68 chelates
|
EP1079862B1
(en)
|
1998-05-20 |
2010-07-07 |
Immunomedics, Inc. |
Therapeutics using a bispecific anti-hla class ii invariant chain x anti-pathogen antibody
|
US20060052321A1
(en)
|
2002-04-05 |
2006-03-09 |
Raitano Arthur B |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
US20030149531A1
(en)
|
2000-12-06 |
2003-08-07 |
Hubert Rene S. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
DK1086223T3
(da)
|
1998-06-01 |
2009-11-30 |
Agensys Inc |
Nye serpentintransmembranantigener udtrykt i humane cancerformer og anvendelser deraf
|
US20040141975A1
(en)
|
1998-06-01 |
2004-07-22 |
Raitano Arthur B. |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
US6833438B1
(en)
|
1999-06-01 |
2004-12-21 |
Agensys, Inc. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
WO2000002587A1
(en)
|
1998-07-13 |
2000-01-20 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
|
US6103524A
(en)
|
1998-07-30 |
2000-08-15 |
Eli Lilly And Company |
Metabotropic glutamate receptor protein and nucleic acid
|
WO2000014234A1
(en)
|
1998-09-08 |
2000-03-16 |
Urocor, Inc. |
Prostate specific promoter and regulation of gene expression
|
US6361774B1
(en)
|
1999-09-17 |
2002-03-26 |
Immunomedics, Inc. |
Methods and compositions for increasing the target-specific toxicity of a chemotherapy drug
|
US6284742B1
(en)
|
1998-09-29 |
2001-09-04 |
Uab Research Foundation |
Immunomodulation by genetic modification of dendritic cells and B cells
|
WO2000034461A2
(en)
|
1998-12-10 |
2000-06-15 |
Board Of Regents, The University Of Texas System |
Compositions and methods of modulating cholesterol metabolism
|
EP1175616A4
(en)
|
1999-04-13 |
2003-08-13 |
Northwest Biotherapeutics Inc |
METHODS FOR DIAGNOSING AND TREATING METASTATIC PROSTATE TUMORS
|
US6416758B1
(en)
|
1999-04-28 |
2002-07-09 |
Board Of Regents, The University Of Texax System |
Antibody conjugate kits for selectively inhibiting VEGF
|
US20090087878A9
(en)
|
1999-05-06 |
2009-04-02 |
La Rosa Thomas J |
Nucleic acid molecules associated with plants
|
WO2001009303A2
(en)
|
1999-07-30 |
2001-02-08 |
Vical Inc. |
Flt-3 LIGAND-ENCODING POLYNUCLEOTIDE AS A POLYNUCLEOTIDE-BASED VACCINE ENHANCER
|
KR100510795B1
(en)
|
1999-08-31 |
2005-08-30 |
|
Compositions and Methods for the Treatment of Tumor
|
US20040209314A1
(en)
|
1999-09-06 |
2004-10-21 |
Institut National De La Sante Et De La Recherche Medicale France |
Means for detection and purification of CD8+ T lymphocyte populations specific to peptides presented in the context of HLA
|
US6342587B1
(en)
|
1999-10-22 |
2002-01-29 |
Ludwig Institute For Cancer Research |
A33 antigen specific immunoglobulin products and uses thereof
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
AU2001256325A1
(en)
|
2000-03-17 |
2001-09-24 |
Boehringer Ingelheim Pharma Kg |
Human and humanized fap-alpha-specific antibodies
|
CA2406993A1
(en)
|
2000-03-24 |
2001-09-27 |
Micromet Ag |
Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex
|
US6608176B2
(en)
|
2000-03-31 |
2003-08-19 |
University Of Miami |
Taste receptor for umami (monosodium glutamate) taste
|
US6573096B1
(en)
|
2000-04-01 |
2003-06-03 |
The Research Foundation At State University Of New York |
Compositions and methods for inhibition of cancer invasion and angiogenesis
|
WO2001074905A1
(en)
|
2000-04-03 |
2001-10-11 |
Antisoma Research Limited |
Compounds for targeting
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
CA2405363A1
(en)
|
2000-04-28 |
2001-11-08 |
Ctl Immunotherapies Corp. |
Epitope synchronization in antigen presenting cells
|
US6861234B1
(en)
|
2000-04-28 |
2005-03-01 |
Mannkind Corporation |
Method of epitope discovery
|
US7834146B2
(en)
|
2000-05-08 |
2010-11-16 |
Monsanto Technology Llc |
Recombinant polypeptides associated with plants
|
US8106174B2
(en)
|
2000-05-08 |
2012-01-31 |
Monsanto Technology Llc |
Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
|
US6375991B1
(en)
|
2000-09-08 |
2002-04-23 |
Albemarle Corporation |
Production of concentrated biocidal solutions
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
WO2002098897A2
(en)
|
2001-06-01 |
2002-12-12 |
Cornell Research Foundation, Inc. |
Modified antibodies to prostate-specific membrane antigen and uses thereof
|
US7666414B2
(en)
|
2001-06-01 |
2010-02-23 |
Cornell Research Foundation, Inc. |
Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
|
US7514078B2
(en)
|
2001-06-01 |
2009-04-07 |
Cornell Research Foundation, Inc. |
Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
|
US20030235833A1
(en)
|
2001-06-18 |
2003-12-25 |
National Institute Of Advanced Industrial Science And Technology |
Guanosine triphosphate-binding protein coupled receptors
|
US20030143668A1
(en)
|
2001-06-18 |
2003-07-31 |
National Institute Of Advanced Industrial |
Guanosine triphosphate-binding protein coupled receptors
|
NZ581474A
(en)
|
2001-08-03 |
2011-04-29 |
Glycart Biotechnology Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
CN1142183C
(zh)
|
2001-08-23 |
2004-03-17 |
北京大学人民医院 |
抗独特型微抗体及其制备方法和应用
|
US7494646B2
(en)
|
2001-09-06 |
2009-02-24 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
JP2005505271A
(ja)
|
2001-09-06 |
2005-02-24 |
アジェンシス, インコーポレイテッド |
癌の処置および検出において有用なsteap−1と名称が与えられる核酸および対応するタンパク質
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
JP2005527474A
(ja)
|
2001-09-20 |
2005-09-15 |
コーネル リサーチ ファンデーション インコーポレーテッド |
前立腺特異的膜抗原に特異的な結合剤を用いて、皮膚障害を治療するかまたは防止するための方法および組成物
|
JP4356454B2
(ja)
|
2001-10-23 |
2009-11-04 |
味の素株式会社 |
新規グルタミン酸受容体とその利用
|
MXPA04003798A
(es)
|
2001-10-25 |
2004-07-30 |
Genentech Inc |
Composiciones de glicoproteina.
|
GB0126378D0
(en)
|
2001-11-02 |
2002-01-02 |
Oxford Biomedica Ltd |
Antigen
|
CN1313617C
(zh)
|
2001-11-07 |
2007-05-02 |
曼康公司 |
编码靶相关抗原表位的表达载体及其设计方法
|
US20040018519A1
(en)
|
2001-11-16 |
2004-01-29 |
Wright ,Jr. George L |
Methods and devices for quantitative detection of prostate specific membrane antigen and other prostatic markers
|
WO2003062375A2
(en)
|
2001-12-19 |
2003-07-31 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
DE60325334D1
(de)
|
2002-02-05 |
2009-01-29 |
Genentech Inc |
Proteinaufreinigung
|
US20040018557A1
(en)
|
2002-03-01 |
2004-01-29 |
Immunomedics, Inc. |
Bispecific antibody point mutations for enhancing rate of clearance
|
DK1483294T3
(da)
|
2002-03-01 |
2010-11-08 |
Immunomedics Inc |
Internaliserende anti-CD74-antistoffer og fremgangsmåder til deres anvendelse
|
AU2003234706A1
(en)
|
2002-04-15 |
2003-11-03 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to tl5
|
WO2003089930A1
(en)
|
2002-04-22 |
2003-10-30 |
Georgetown University |
Peripheral-type benzodiazepine receptor expression level as an index of organ damage and regeneration
|
CA2478925C
(en)
|
2002-04-26 |
2016-06-07 |
Robert Lee Fahrner |
Non-affinity purification of proteins
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
US7563433B2
(en)
|
2007-01-11 |
2009-07-21 |
Immunomedics, Inc. |
Methods and compositions for F-18 labeling of proteins, peptides and other molecules
|
US7993626B2
(en)
|
2007-01-11 |
2011-08-09 |
Immunomedics, Inc. |
Methods and compositions for F-18 labeling of proteins, peptides and other molecules
|
US7597876B2
(en)
|
2007-01-11 |
2009-10-06 |
Immunomedics, Inc. |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
|
EP1534331B1
(en)
|
2002-06-21 |
2014-10-29 |
Johns Hopkins University School of Medicine |
Membrane associated tumor endothelium markers
|
US20080260744A1
(en)
|
2002-09-09 |
2008-10-23 |
Omeros Corporation |
G protein coupled receptors and uses thereof
|
EP1581648A2
(en)
|
2002-09-09 |
2005-10-05 |
Nura, Inc. |
G protein coupled receptors and uses thereof
|
US9809654B2
(en)
|
2002-09-27 |
2017-11-07 |
Vaccinex, Inc. |
Targeted CD1d molecules
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
WO2004050836A2
(en)
|
2002-11-27 |
2004-06-17 |
Biogen Idec Ma Inc. |
Humanized antibodies against monocyte chemotactic proteins
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
JP2007520996A
(ja)
|
2003-01-15 |
2007-08-02 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
44390、54181、211、5687、884、1405、636、4421、5410、30905、2045、16405、18560、2047、33751、52872、14063、20739、32544、43239、44373、51164、53010、16852、1587、2207、22245、2387、52908、69112、14990、18547、115、579、15985、15625、760、18603、2395、2554、8675、32720、4809、14303、16816、17827、32620、577、619、1423、2158、8263、15402、16209、16386、21165、30911、41897、1643、2543、9626、13231、32409、84260、2882、8203、32678または55053を用いて泌尿器科障害を処置するための方法および組成物
|
MXPA05007781A
(es)
|
2003-01-22 |
2005-09-30 |
Glycart Biotechnology Ag |
Constructos de fusion y uso de los mismos para producir anticuerpos con afinidad incrementada de enlace al receptor fc y funcion efectora.
|
ATE517638T1
(de)
|
2003-01-31 |
2011-08-15 |
Immunomedics Inc |
Verfahren und zubereitungen zum verabreichen von therapeutischen und diagnostischen mitteln
|
CN1791679A
(zh)
|
2003-03-19 |
2006-06-21 |
伊索格尼斯股份有限公司 |
基于CD8α链的具有降低的免疫原性的基因治疗载体
|
WO2004088279A2
(en)
|
2003-03-28 |
2004-10-14 |
Iowa State University Research Foundation, Inc. |
Allosteric probes and methods
|
GB0308988D0
(en)
|
2003-04-17 |
2003-05-28 |
Univ Singapore |
Molecule
|
US7595379B2
(en)
|
2003-05-30 |
2009-09-29 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
SI1629088T1
(sl)
|
2003-05-30 |
2012-08-31 |
Agensys Inc |
Antigen izvornih celic prostate (psca) in njegova podzaporedja
|
US7541442B2
(en)
|
2003-05-30 |
2009-06-02 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
ATE455127T1
(de)
|
2003-05-31 |
2010-01-15 |
Micromet Ag |
Humane anti-humane cd3-bindungsmoleküle
|
US7919089B2
(en)
|
2003-05-31 |
2011-04-05 |
Micromet Ag |
Pharmaceutical composition comprising a bispecific antibody for EpCAM
|
CN1822857A
(zh)
|
2003-06-02 |
2006-08-23 |
阿莱克申药物公司 |
去免疫原性抗cd3抗体
|
EP1641826A2
(en)
|
2003-06-27 |
2006-04-05 |
Biogen Idec MA Inc. |
Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
|
EP3722309A1
(en)
|
2003-07-28 |
2020-10-14 |
Genentech, Inc. |
Reducing protein a leaching during protein a affinity chromatography
|
GB0321805D0
(en)
|
2003-09-18 |
2003-10-15 |
Univ Wales Medicine |
Human tumour growth patterns
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US7569389B2
(en)
|
2004-09-30 |
2009-08-04 |
Ceres, Inc. |
Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics
|
US20060150283A1
(en)
|
2004-02-13 |
2006-07-06 |
Nickolai Alexandrov |
Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
|
US20120159672A1
(en)
|
2004-02-06 |
2012-06-21 |
Nickolai Alexandrov |
Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
|
US7524813B2
(en)
|
2003-10-10 |
2009-04-28 |
Novo Nordisk Health Care Ag |
Selectively conjugated peptides and methods of making the same
|
BRPI0415457A
(pt)
|
2003-10-16 |
2006-12-05 |
Micromet Ag |
constructo de ligação especìfico de cd3 citotoxicamente ativo, seu processo de produção, composição compreendendo o mesmo, seqüência de ácido nucléico, vetor, hospedeiro, seus usos na preparação de uma composição farmacêutica e kit compreendendo os mesmo
|
US20050176028A1
(en)
|
2003-10-16 |
2005-08-11 |
Robert Hofmeister |
Deimmunized binding molecules to CD3
|
ES2428358T3
(es)
|
2003-10-17 |
2013-11-07 |
Novo Nordisk A/S |
Terapia de combinación
|
ITPD20030264A1
(it)
|
2003-10-30 |
2005-04-30 |
Xeptagen Spa |
Metodo di diagnosi altamente specifico per neoplasie
|
ES2605443T3
(es)
|
2003-11-06 |
2017-03-14 |
Seattle Genetics, Inc. |
Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
EP1704228B1
(en)
|
2004-01-16 |
2012-04-11 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Immunokinases
|
US20060235212A1
(en)
|
2004-12-22 |
2006-10-19 |
Nickolai Alexandrov |
Nucleic acid sequences encoding zinc finger proteins
|
MXPA06009253A
(es)
|
2004-02-16 |
2007-04-18 |
Micromet Ag |
Moleculas de enlace menos inmunogenicas.
|
WO2005082023A2
(en)
|
2004-02-23 |
2005-09-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
WO2005094882A1
(en)
|
2004-03-03 |
2005-10-13 |
Millennium Pharmaceuticals, Inc. |
Modified antibodies to prostate-specific membrane antigen and uses thereof
|
US7273608B2
(en)
|
2004-03-11 |
2007-09-25 |
City Of Hope |
Humanized anti-CEA T84.66 antibody and uses thereof
|
US7662936B2
(en)
|
2004-04-07 |
2010-02-16 |
Genentech, Inc. |
Mass spectrometry of antibody conjugates
|
US8008442B2
(en)
|
2004-04-22 |
2011-08-30 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
DE102004023187A1
(de)
|
2004-05-11 |
2005-12-01 |
Ganymed Pharmaceuticals Ag |
Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
|
CN102973947A
(zh)
|
2004-06-01 |
2013-03-20 |
健泰科生物技术公司 |
抗体-药物偶联物和方法
|
US20080227736A1
(en)
|
2004-06-03 |
2008-09-18 |
Regents Of The University Of California, |
Targeting Pseudotyped Retroviral Vectors
|
US20050281740A1
(en)
|
2004-06-16 |
2005-12-22 |
Glen Gong |
Imaging damaged lung tissue
|
US20060159689A1
(en)
|
2004-06-17 |
2006-07-20 |
Chih-Sheng Chiang |
Combinations of tumor-associated antigens in diagnostics for various types of cancers
|
EA010374B1
(ru)
|
2004-07-16 |
2008-08-29 |
Микромет Аг |
Полипептиды с повышенной экспрессией
|
US7521541B2
(en)
|
2004-09-23 |
2009-04-21 |
Genetech Inc. |
Cysteine engineered antibodies and conjugates
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
WO2006049599A1
(en)
|
2004-10-28 |
2006-05-11 |
The General Hospital Corporation |
Methods of detection and therapy for atheromatous plaques using immune modulation
|
WO2006050058A2
(en)
|
2004-10-28 |
2006-05-11 |
The General Hospital Corporation |
Methods of detection and therapy of inflamed tissues using immune modulation
|
US7947839B2
(en)
|
2004-12-01 |
2011-05-24 |
Genentech, Inc. |
Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use
|
US20070134243A1
(en)
|
2004-12-01 |
2007-06-14 |
Gazzard Lewis J |
Antibody drug conjugates and methods
|
US7335760B2
(en)
|
2004-12-22 |
2008-02-26 |
Ceres, Inc. |
Nucleic acid sequences encoding zinc finger proteins
|
CA2491067A1
(en)
|
2004-12-24 |
2006-06-24 |
Stichting Katholieke Universiteit |
Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
|
WO2006082406A2
(en)
|
2005-02-03 |
2006-08-10 |
Antitope Limited |
Human antibodies and proteins
|
US7678371B2
(en)
|
2005-03-04 |
2010-03-16 |
Biogen Idec Ma Inc. |
Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
|
CN1854295A
(zh)
|
2005-04-25 |
2006-11-01 |
上海新生源医药研究有限公司 |
卵巢癌抗独特型微抗体的生产方法
|
PE20061324A1
(es)
|
2005-04-29 |
2007-01-15 |
Centocor Inc |
Anticuerpos anti-il-6, composiciones, metodos y usos
|
GB2426581A
(en)
|
2005-05-27 |
2006-11-29 |
Univ Nottingham |
Immunoassay methods
|
JP2007014267A
(ja)
|
2005-07-07 |
2007-01-25 |
Toyama Univ |
B型肝炎ウイルスのHBs抗原に対するモノクローナル抗体、それに関連する遺伝子およびペプチド、並びにB型肝炎ウイルスの検定方法、B型肝炎の診断方法、治療方法
|
CA2614640A1
(en)
|
2005-07-11 |
2007-01-18 |
Macrogenics, Inc. |
Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
|
US20080279850A1
(en)
|
2005-07-25 |
2008-11-13 |
Trubion Pharmaceuticals, Inc. |
B-Cell Reduction Using CD37-Specific and CD20-Specific Binding Molecules
|
DK1912675T3
(en)
|
2005-07-25 |
2014-03-24 |
Emergent Product Dev Seattle |
B-cell reduction using specific and cd37-cd20-specific binding molecules
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
WO2007100385A2
(en)
|
2005-10-31 |
2007-09-07 |
Genentech, Inc. |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
WO2007087673A1
(en)
|
2006-02-01 |
2007-08-09 |
Arana Therapeutics Limited |
Domain antibody construct
|
US20070212331A1
(en)
|
2006-03-07 |
2007-09-13 |
Baldassare Joseph J |
Methods and compositions for selectively killing cells
|
ATE509033T1
(de)
|
2006-03-20 |
2011-05-15 |
Univ California |
Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
|
BRPI0708998A2
(pt)
|
2006-03-21 |
2011-06-21 |
Wyeth Corp |
anticorpo que se liga especificamente ao rage; anticorpo quimérico ou um fragmento de ligação rage do mesmo; anticorpo humanizado ou um fragmento de ligação rage do mesmo; anticorpo humanizado que se liga especificamente ao rage ou um fragmento de ligação rage do mesmo; anticorpo que se liga especificamente ao rage e bloqueia a ligação de um parceiro corporal rage; ácido nucléico isolado; método de tratamento de um indivìduo que tem uma doença ou transtorno relacionado com rage; método de tratamento de sepse ou choque séptico em um indivìduo humano; método de tratamento de listeriose sistêmica em um indivìduo humano; e método de inibir a ligação de um parceiro de ligação rage (rage-bp), o rage em um indivìduo mamìfero
|
WO2007112316A2
(en)
|
2006-03-24 |
2007-10-04 |
Morton Donald L |
Mycobacterial immunotherapy for cancer treatment
|
ES2776100T3
(es)
|
2006-03-31 |
2020-07-29 |
Massachusetts Inst Technology |
Sistema para el suministro dirigido de agentes terapéuticos
|
US7566276B2
(en)
|
2006-04-14 |
2009-07-28 |
Dogleg Right Corporation |
Multi-piece putter head having an insert
|
US20110052697A1
(en)
|
2006-05-17 |
2011-03-03 |
Gwangju Institute Of Science & Technology |
Aptamer-Directed Drug Delivery
|
EP2520935A3
(en)
|
2006-08-09 |
2013-02-13 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
AR062223A1
(es)
|
2006-08-09 |
2008-10-22 |
Glycart Biotechnology Ag |
Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas
|
CN101632020B
(zh)
|
2006-09-13 |
2013-11-27 |
昂西免疫有限公司 |
改进的免疫测定方法
|
WO2008050255A2
(en)
|
2006-10-25 |
2008-05-02 |
Koninklijke Philips Electronics N. V. |
Contrast agents for detecting prostate cancer
|
WO2008079280A1
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
US20160045626A1
(en)
|
2007-01-11 |
2016-02-18 |
Immunomedics, Inc. |
Methods and Compositions for Improved Labeling of Targeting Peptides
|
US8545809B2
(en)
|
2007-01-11 |
2013-10-01 |
Immunomedics, Inc. |
Methods and compositions for improved 18F labeling of proteins, peptides and other molecules
|
US8709382B2
(en)
|
2007-01-11 |
2014-04-29 |
Immunomedics, Inc. |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
|
US20150086482A1
(en)
|
2007-01-11 |
2015-03-26 |
Immunomedics, Inc. |
Dye Conjugated Peptides for Fluorescent Imaging
|
US8889100B2
(en)
|
2007-01-11 |
2014-11-18 |
Immunomedics, Inc. |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
|
CN101568352B
(zh)
|
2007-01-11 |
2013-08-21 |
免疫医学股份有限公司 |
用于蛋白质、肽和其他分子的改进的f-18标记的方法和组合物
|
WO2008127735A1
(en)
|
2007-04-13 |
2008-10-23 |
Stemline Therapeutics, Inc. |
Il3ralpha antibody conjugates and uses thereof
|
US20080260738A1
(en)
|
2007-04-18 |
2008-10-23 |
Moore Margaret D |
Single chain fc, methods of making and methods of treatment
|
KR20100021601A
(ko)
|
2007-05-14 |
2010-02-25 |
바이오겐 아이덱 엠에이 인코포레이티드 |
단일-쇄 Fc(ScFc) 부분, 이를 포함하는 결합 폴리펩타이드, 및 이에 관련된 방법
|
KR101580938B1
(ko)
|
2007-06-01 |
2015-12-30 |
유니버시티 오브 매릴랜드, 발티모어 |
면역글로불린 불변영역 Fc 수용체 결합제
|
WO2009017823A2
(en)
|
2007-08-01 |
2009-02-05 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health Of Human Services, National Institutes Of Health |
A fold-back diabody diphtheria toxin immunotoxin and methods of use
|
JP6126773B2
(ja)
|
2007-09-04 |
2017-05-10 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原(psca)抗体
|
KR101922788B1
(ko)
|
2007-09-26 |
2018-11-27 |
추가이 세이야쿠 가부시키가이샤 |
항체 정상영역 개변체
|
EP2220245B1
(en)
|
2007-10-17 |
2015-04-22 |
The Board of Trustees of The Leland Stanford Junior University |
Method and composition for crystallizing g protein-coupled receptors
|
EP2207564B1
(en)
|
2007-10-18 |
2016-10-05 |
Bavarian Nordic A/S |
Use of mva to treat prostate cancer
|
CA2703140A1
(en)
|
2007-10-25 |
2009-04-30 |
Viventia Biotech Inc. |
Antibodies against a cancer-associated epitope of variant hnrnpg and uses thereof
|
US20100322861A1
(en)
|
2007-11-27 |
2010-12-23 |
Gambhir Sanjiv S |
Engineered cells, imaging report gene/probe systems, and methods of imaging
|
US9107858B2
(en)
|
2007-12-05 |
2015-08-18 |
Wisconsin Alumni Research Foundation |
Dendritic cell targeting compositions and uses thereof
|
WO2009097128A1
(en)
|
2008-01-29 |
2009-08-06 |
Ludwig Institute For Cancer Research Ltd. |
Membrane transporter napi2b (slc34a2) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy
|
US8043830B2
(en)
|
2008-02-01 |
2011-10-25 |
The Regents Of The University Of California |
Biotin-ligase system for secretion of biotinylated protein
|
EP2240495B1
(en)
|
2008-02-01 |
2015-07-15 |
Genentech, Inc. |
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
|
ITTO20080313A1
(it)
|
2008-04-22 |
2009-10-23 |
Marco Colombatti |
Anticorpo monoclonale isolato o suo frammento legante l'antigene specifico di membrana della prostata, suoi coniugati e suoi usi
|
TW200947474A
(en)
|
2008-05-05 |
2009-11-16 |
Ren-Huan Pan |
Manufacturing equipment and method of quadratic arc alignment dua-turret formation center, and miniature milliohm current sensors manufactured thereof
|
JP5539971B2
(ja)
|
2008-05-13 |
2014-07-02 |
ジェネンテック, インコーポレイテッド |
ビーズに基づく親和性キャプチャおよび質量分析による抗体薬剤コンジュゲートの分析
|
WO2010003108A2
(en)
|
2008-07-02 |
2010-01-07 |
Trubion Pharmaceuticals, Inc. |
TNF-α ANTAGONIST MULTI-TARGET BINDING PROTEINS
|
US20110177070A1
(en)
|
2008-07-02 |
2011-07-21 |
Emergent Product Development Seatlle, LLC |
TGF-Beta Antagonist Multi-Target Binding Proteins
|
US8728738B2
(en)
|
2008-07-02 |
2014-05-20 |
Assistance Publique-Hopitaux De Paris |
Method for predicting clinical outcome of patients with non-small cell lung carcinoma
|
JP6067222B2
(ja)
|
2008-07-15 |
2017-01-25 |
ジェネンテック, インコーポレイテッド |
アントラサイクリン誘導体コンジュゲート、その調製方法及び抗腫瘍化合物としてのその用途
|
US20100069616A1
(en)
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
JP5309775B2
(ja)
|
2008-08-07 |
2013-10-09 |
セイコーエプソン株式会社 |
放電灯の駆動装置および駆動方法、光源装置並びに画像表示装置
|
MX2011001909A
(es)
|
2008-08-20 |
2011-03-21 |
Centocor Ortho Biotech Inc |
Anticuerpos anti-interleucina-13 modificados, composiciones, metodos y usos.
|
CA2732653C
(en)
|
2008-09-08 |
2014-10-14 |
Conocophillips Company |
System for incondensable component separation in a liquefied natural gas facility
|
US8487077B2
(en)
|
2008-09-16 |
2013-07-16 |
The Regents Of The University Of California |
Simplified one-pot synthesis of [18F]SFB for radiolabeling
|
WO2010037397A1
(en)
|
2008-10-01 |
2010-04-08 |
Dako Denmark A/S |
Mhc multimers in cmv immune monitoring
|
CN107056951A
(zh)
|
2008-10-02 |
2017-08-18 |
阿帕特夫研究和发展有限公司 |
Cd86拮抗物多靶点结合蛋白
|
MX2011003763A
(es)
|
2008-10-10 |
2011-04-27 |
Emergent Product Dev Seattle |
Inmunoterapeuticos de completo tcr.
|
WO2010043927A1
(en)
|
2008-10-13 |
2010-04-22 |
Xeptagen Spa |
Method for the preparation of immunoconjugates and use thereof
|
BRPI0919882A8
(pt)
|
2008-10-30 |
2017-09-19 |
Caris Life Sciences Luxembourg Holdings |
Métodos para avaliar padrões de rna
|
EP2350320A4
(en)
|
2008-11-12 |
2012-11-14 |
Caris Life Sciences Luxembourg Holdings |
METHODS AND SYSTEMS FOR USING EXOSOMES TO DETERMINE PHENOTYPES
|
AU2009313877A1
(en)
|
2008-11-13 |
2011-06-30 |
Emergent Product Development Seattle, Llc |
CD37 immunotherapeutic combination therapies and uses thereof
|
US20100143353A1
(en)
|
2008-12-04 |
2010-06-10 |
Mosser David M |
POLYPEPTIDES COMPRISING Fc FRAGMENTS OF IMMUNOGLOBULIN G (lgG) AND METHODS OF USING THE SAME
|
WO2010074702A1
(en)
|
2008-12-16 |
2010-07-01 |
Millipore Corporation |
Purification of proteins
|
WO2010073462A1
(ja)
|
2008-12-25 |
2010-07-01 |
東海ゴム工業株式会社 |
流体封入式防振装置
|
JP5851842B2
(ja)
|
2009-01-12 |
2016-02-03 |
サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. |
改変した抗体組成物、それを作製および使用する方法
|
US8383778B2
(en)
|
2009-01-29 |
2013-02-26 |
Abbvie Inc. |
IL-1 binding proteins
|
ES2712732T3
(es)
|
2009-02-17 |
2019-05-14 |
Cornell Res Foundation Inc |
Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
|
WO2010102195A2
(en)
|
2009-03-06 |
2010-09-10 |
The Johns Hopkins University |
Annexin a11 and associated genes as biomarkers for cancer
|
JP5923035B2
(ja)
|
2009-03-24 |
2016-05-24 |
バイオセプト インコーポレイティッド |
細胞の捕捉および解析のデバイスおよび方法
|
CA2757897A1
(en)
|
2009-04-08 |
2010-10-14 |
Anna M. Wu |
Human protein scaffold with controlled serum pharmacokinetics
|
ES2708124T3
(es)
|
2009-04-27 |
2019-04-08 |
Oncomed Pharm Inc |
Procedimiento para preparar moléculas heteromultiméricas
|
WO2010136492A2
(en)
|
2009-05-28 |
2010-12-02 |
Glaxo Group Limited |
Antigen-binding proteins
|
TW201107345A
(en)
|
2009-05-28 |
2011-03-01 |
Glaxo Group Ltd |
Immunoglobulins
|
CA2766409C
(en)
|
2009-07-03 |
2023-04-25 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
WO2011003171A1
(en)
|
2009-07-08 |
2011-01-13 |
Smart Technologies Ulc |
Three-dimensional widget manipulation on a multi-touch panel
|
TWM383852U
(en)
|
2009-07-13 |
2010-07-01 |
Speedtech Corp |
An improvement of the universal serial bus connector
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
CN102573925B
(zh)
|
2009-10-05 |
2015-08-05 |
佳能株式会社 |
光声成像用造影剂和使用所述光声成像用造影剂的光声成像方法
|
EP2507383B1
(en)
|
2009-12-02 |
2013-10-16 |
Unilever NV |
Improved method for screening a potential modulator compound of a taste receptor
|
RU2673908C2
(ru)
|
2009-12-02 |
2018-12-03 |
Имэджинэб, Инк. |
Мини-антитела j591 и цис-диатела для направленной доставки простата-специфичного мембранного антигена (psma) человека и способы их применения
|
IN2012DN03177A
(es)
|
2009-12-04 |
2015-09-25 |
Immunomedics Inc |
|
JP2013514788A
(ja)
|
2009-12-23 |
2013-05-02 |
アビペップ ピーティーワイ リミテッド |
イムノコンジュゲート及びその作製方法2
|
AU2010343056A1
(en)
|
2009-12-29 |
2012-08-02 |
Emergent Product Development Seattle, Llc |
Ron binding constructs and methods of use thereof
|
SG183171A1
(en)
*
|
2010-02-04 |
2012-09-27 |
Agency Science Tech & Res |
Use of novel markers of pluripotent stem cells
|
WO2011100270A2
(en)
|
2010-02-09 |
2011-08-18 |
OSI Pharmaceuticals, LLC |
Pet imaging
|
EP2542696B1
(en)
|
2010-03-01 |
2016-09-28 |
Caris Life Sciences Switzerland Holdings GmbH |
Biomarkers for theranostics
|
UA108227C2
(xx)
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
US9812638B2
(en)
|
2010-03-19 |
2017-11-07 |
Globalfoundries Inc. |
Backend of line (BEOL) compatible high current density access device for high density arrays of electronic components
|
GB201014033D0
(en)
*
|
2010-08-20 |
2010-10-06 |
Ucb Pharma Sa |
Biological products
|
WO2012030735A1
(en)
|
2010-08-30 |
2012-03-08 |
Confometrx, Inc. |
Method and composition for crystallizing a family c gpcr
|
ES2495430T3
(es)
|
2010-10-28 |
2014-09-17 |
Avicenna Research Institute |
Una forma de PRELP de 38 KDA como nuevo diagnóstico y objetivo terapéutico
|
US20120144110A1
(en)
|
2010-12-02 |
2012-06-07 |
Lsi Corporation |
Methods and structure for storage migration using storage array managed server agents
|
EP2471543A1
(en)
|
2010-12-02 |
2012-07-04 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Tolerance induction or immunosupression to prevent in particular Graft-versus-Host-Disease (GvHD) by short-term pre-incubation of transplanted cell suspensions, tissues or organs coated with ligands to cell surface molecules
|
EP2476754A1
(en)
|
2011-01-14 |
2012-07-18 |
Bundesrepublik Deutschland, Letztvertreten Durch Den Präsidenten Des Paul-Ehrlich-Instituts |
Methods for the identification and repair of amino acid residues destabilizing single-chain variable fragments (scFv)
|
BR112013017980A2
(pt)
|
2011-01-14 |
2017-06-27 |
Redwood Bioscience Inc |
polipeptídeos de imunoglobulina marcado com aldeído e método de uso dos mesmos
|
CN103796677B
(zh)
|
2011-04-20 |
2019-08-16 |
健玛保 |
针对her2和cd3的双特异性抗体
|
JP6325979B2
(ja)
|
2011-08-03 |
2018-05-16 |
ザ チルドレンズ メディカル センター コーポレーション |
インフルエンザ血球凝集素の受容体結合ポケットを認識する広域中和ヒト抗体
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
GB201203051D0
(en)
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
GB201203071D0
(en)
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
WO2013130177A1
(en)
|
2012-02-28 |
2013-09-06 |
Cornell University |
Psma as a biomarker for androgen activity in prostate cancer
|
US10501513B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides for the production of oncology-related proteins and peptides
|
EP2895203A4
(en)
|
2012-06-15 |
2016-09-28 |
Imaginab Inc |
ANTIGEN BINDING CONSTRUCTIONS FOR CD3
|
SI3495387T1
(sl)
|
2012-07-13 |
2021-12-31 |
Roche Glycart Ag |
Bispecifična protitelesa proti VEGF/proti ANG-2 in njihova uporaba pri zdravljenju bolezni očesnih žil
|
WO2014025828A1
(en)
|
2012-08-06 |
2014-02-13 |
The Regents Of The University Of California |
Engineered antibody fragments for targeting and imaging cd8 expression in vivo
|
JP2016510755A
(ja)
*
|
2013-03-06 |
2016-04-11 |
メリマック ファーマシューティカルズ インコーポレーティッド |
抗C−METタンデムFc二重特異性抗体
|
US20140271462A1
(en)
|
2013-03-13 |
2014-09-18 |
Imaginab, Inc. |
Antigen binding constructs to cd8
|
US9168300B2
(en)
*
|
2013-03-14 |
2015-10-27 |
Oncomed Pharmaceuticals, Inc. |
MET-binding agents and uses thereof
|
SI2970422T1
(en)
*
|
2013-03-15 |
2018-07-31 |
F. Hoffmann-La Roche Ag |
IL-22 polypeptides and IL-22-Fc fusion proteins and procedures for use
|
TWI747803B
(zh)
|
2013-04-29 |
2021-12-01 |
瑞士商赫孚孟拉羅股份公司 |
人類結合fcrn之經修飾抗體及使用方法
|
MX2015015060A
(es)
|
2013-04-29 |
2016-02-25 |
Hoffmann La Roche |
Anticuerpos asimetricos modificados que se unen al receptor fc y metodos de uso.
|
MX2016008782A
(es)
|
2014-01-15 |
2016-09-08 |
Hoffmann La Roche |
Variantes de region fc con union mejorada de la proteina a.
|
KR20160107190A
(ko)
|
2014-01-15 |
2016-09-13 |
에프. 호프만-라 로슈 아게 |
변형된 FcRn-결합 및 유지된 단백질 A-결합 성질을 갖는 Fc-영역 변이체
|
CN105873948B
(zh)
|
2014-01-15 |
2021-04-13 |
豪夫迈·罗氏有限公司 |
具有修饰的FCRN结合性质的Fc区变体
|
KR102460736B1
(ko)
|
2014-05-10 |
2022-10-31 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
화학적으로-로킹된 이중특이적 항체
|
EP2966085A1
(en)
|
2014-07-11 |
2016-01-13 |
Boehringer Ingelheim International GmbH |
Antibody IgG1 with a modified heavy chain constant region
|
WO2016016299A1
(en)
|
2014-07-29 |
2016-02-04 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
CA2982246A1
(en)
|
2015-04-17 |
2016-10-20 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins with tunable affinities
|
WO2016176652A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
JP6985934B2
(ja)
|
2015-04-29 |
2021-12-22 |
フレッド ハッチンソン キャンサー リサーチ センター |
操作された造血幹細胞/前駆細胞及び非tエフェクター細胞、ならびにその使用
|
BR112017023829A2
(pt)
|
2015-05-06 |
2018-07-31 |
Janssen Biotech Inc |
agentes de ligação biespecíficos de antígeno de membrana específico da próstata (psma) e usos dos mesmos
|
US11820807B2
(en)
*
|
2015-06-12 |
2023-11-21 |
Ubi Pharma Inc |
Immunoglobulin fusion proteins and uses thereof
|
US20160362473A1
(en)
*
|
2015-06-12 |
2016-12-15 |
Ubi Pharma Inc |
Immunoglobulin fusion proteins and uses thereof
|
WO2017007807A1
(en)
|
2015-07-07 |
2017-01-12 |
Immunomedics, Inc. |
IMPROVED METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES
|
EP4137158A1
(en)
|
2015-08-07 |
2023-02-22 |
Imaginab, Inc. |
Antigen binding constructs to target molecules
|
JP2018534245A
(ja)
|
2015-09-14 |
2018-11-22 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法
|
WO2017059397A1
(en)
|
2015-10-01 |
2017-04-06 |
Whitehead Institute For Biomedical Research |
Labeling of antibodies
|
KR20180108662A
(ko)
|
2016-02-15 |
2018-10-04 |
프라운호퍼-게젤샤프트 츄어 푀르더룽 데어 안게반텐 포르슝에.파우. |
변형된 이식편의 사전 사용에 의한 이식편 거부의 방지
|
EP3440101B1
(en)
|
2016-04-04 |
2021-10-06 |
Indi Molecular, Inc. |
Cd8-specific capture agents, compositions, and methods of using and making
|
EP3443001A4
(en)
|
2016-04-11 |
2020-04-29 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
US11596699B2
(en)
|
2016-04-29 |
2023-03-07 |
CureVac SE |
RNA encoding an antibody
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
EP3266465A1
(en)
|
2016-07-06 |
2018-01-10 |
Julius-Maximilians-Universität Würzburg |
Immune complexes
|
WO2018053328A1
(en)
|
2016-09-16 |
2018-03-22 |
Duke University |
Bispecific molecules comprising an hiv-1 envelope targeting arm
|
US10626165B2
(en)
|
2016-12-14 |
2020-04-21 |
Janssen Biotech, Inc. |
CD8a-binding fibronectin type III domains
|
CN110418802A
(zh)
|
2017-01-20 |
2019-11-05 |
朱诺治疗学有限公司 |
细胞表面缀合物及相关的细胞组合物和方法
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
WO2018187215A1
(en)
|
2017-04-03 |
2018-10-11 |
Merrimack Pharmaceuticals, Inc. |
Bispecific 4-1bb agonist molecules
|
KR20220147684A
(ko)
|
2017-05-10 |
2022-11-03 |
더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 |
최적화된 핵산 항체 작제물
|
WO2018224951A2
(en)
*
|
2017-06-05 |
2018-12-13 |
Janssen Biotech, Inc. |
Engineered multispecific antibodies and other multimeric proteins with asymmetrical ch2-ch3 region mutations
|
WO2018232188A1
(en)
|
2017-06-15 |
2018-12-20 |
Memorial Sloan Kettering Cancer Center |
Anti-l1-cam antibodies and uses thereof
|
WO2019012147A1
(en)
|
2017-07-13 |
2019-01-17 |
Institut Gustave-Roussy |
RADIOMY-BASED IMAGING TOOL FOR MONITORING INFILTRATION AND TUMOR LYMPHOCYTE AND RESULTS IN CANCER PATIENTS TREATED WITH ANTI-PD-1 / PD-L1 AGENTS
|
AU2018307744A1
(en)
|
2017-07-24 |
2020-02-13 |
Regeneron Pharmaceuticals, Inc. |
Anti-CD8 antibodies and uses thereof
|
CA3069930A1
(en)
|
2017-08-09 |
2019-02-14 |
Orionis Biosciences Inc. |
Cd8 binding agents
|
EP3665197A2
(en)
|
2017-08-11 |
2020-06-17 |
H. Hoffnabb-La Roche Ag |
Anti-cd8 antibodies and uses thereof
|
US11672877B2
(en)
|
2017-08-23 |
2023-06-13 |
Wayne State University |
In vivo immunoimaging of interferon-gamma
|
US11555072B2
(en)
|
2017-09-23 |
2023-01-17 |
Memorial Sloan Kettering Cancer Center |
A33 antibody compositions and methods of using the same in radioimmunotherapy
|
CA3090793A1
(en)
|
2018-02-16 |
2019-08-22 |
Kite Pharma, Inc. |
Modified pluripotent stem cells and methods of making and use
|
EP3765031A4
(en)
|
2018-03-14 |
2022-03-23 |
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|
AU2019282248A1
(en)
|
2018-06-08 |
2021-01-07 |
Imaginab, Inc. |
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|
JP2022501402A
(ja)
|
2018-09-28 |
2022-01-06 |
イマジナブ・インコーポレーテッド |
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|